| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/CRX_DN.V1_UP |
| Similar Terms | |
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269 genes differentially expressed following the CRX_DN.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| ABCA4 | ATP-binding cassette, sub-family A (ABC1), member 4 |
| AGR2 | anterior gradient 2 |
| ALPK2 | alpha-kinase 2 |
| ALPL | alkaline phosphatase, liver/bone/kidney |
| ANKRD33 | ankyrin repeat domain 33 |
| AQP1 | aquaporin 1 (Colton blood group) |
| ARG2 | arginase 2 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BATF2 | basic leucine zipper transcription factor, ATF-like 2 |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| BMP15 | bone morphogenetic protein 15 |
| BST1 | bone marrow stromal cell antigen 1 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B |
| C14ORF37 | chromosome 14 open reading frame 37 |
| C16ORF74 | chromosome 16 open reading frame 74 |
| CABP4 | calcium binding protein 4 |
| CCDC107 | coiled-coil domain containing 107 |
| CCDC64 | coiled-coil domain containing 64 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa |
| CKMT1A | creatine kinase, mitochondrial 1A |
| CLDN7 | claudin 7 |
| COL19A1 | collagen, type XIX, alpha 1 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| DDHD1 | DDHD domain containing 1 |
| DHH | desert hedgehog |
| DOCK8 | dedicator of cytokinesis 8 |
| DOHH | deoxyhypusine hydroxylase/monooxygenase |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| DUSP14 | dual specificity phosphatase 14 |
| ESRRB | estrogen-related receptor beta |
| FAAH | fatty acid amide hydrolase |
| FAIM | Fas apoptotic inhibitory molecule |
| FAM107B | family with sequence similarity 107, member B |
| FAM161A | family with sequence similarity 161, member A |
| GAS7 | growth arrest-specific 7 |
| GCKR | glucokinase (hexokinase 4) regulator |
| GNAT1 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 |
| GPSM2 | G-protein signaling modulator 2 |
| GPSM3 | G-protein signaling modulator 3 |
| GRK1 | G protein-coupled receptor kinase 1 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GUCA1B | guanylate cyclase activator 1B (retina) |
| GZMM | granzyme M (lymphocyte met-ase 1) |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA1B | heat shock 70kDa protein 1B |
| IER3 | immediate early response 3 |
| INSL5 | insulin-like 5 |
| JAG1 | jagged 1 |
| KCNE2 | potassium channel, voltage gated subfamily E regulatory beta subunit 2 |
| KCNJ14 | potassium channel, inwardly rectifying subfamily J, member 14 |
| KLKB1 | kallikrein B, plasma (Fletcher factor) 1 |
| KRT18 | keratin 18, type I |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MDM1 | Mdm1 nuclear protein homolog (mouse) |
| MEF2C | myocyte enhancer factor 2C |
| MMP23B | matrix metallopeptidase 23B |
| MYLK | myosin light chain kinase |
| MYRF | myelin regulatory factor |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
| NRM | nurim (nuclear envelope membrane protein) |
| NXNL1 | nucleoredoxin-like 1 |
| NXNL2 | nucleoredoxin-like 2 |
| ONECUT1 | one cut homeobox 1 |
| OPN1MW | opsin 1 (cone pigments), medium-wave-sensitive |
| OPN1SW | opsin 1 (cone pigments), short-wave-sensitive |
| OSGEP | O-sialoglycoprotein endopeptidase |
| PACRG | PARK2 co-regulated |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PDE6A | phosphodiesterase 6A, cGMP-specific, rod, alpha |
| PDE6H | phosphodiesterase 6H, cGMP-specific, cone, gamma |
| PDIA5 | protein disulfide isomerase family A, member 5 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit |
| PPAP2C | phosphatidic acid phosphatase type 2C |
| PPP1R42 | protein phosphatase 1, regulatory subunit 42 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 |
| RAD51 | RAD51 recombinase |
| RANGRF | RAN guanine nucleotide release factor |
| RCVRN | recoverin |
| RDH12 | retinol dehydrogenase 12 (all-trans/9-cis/11-cis) |
| RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) |
| REEP6 | receptor accessory protein 6 |
| RGR | retinal G protein coupled receptor |
| RHPN1 | rhophilin, Rho GTPase binding protein 1 |
| RNF123 | ring finger protein 123 |
| RNF207 | ring finger protein 207 |
| RPE65 | retinal pigment epithelium-specific protein 65kDa |
| RPGRIP1 | retinitis pigmentosa GTPase regulator interacting protein 1 |
| RS1 | retinoschisin 1 |
| RTBDN | retbindin |
| SELENBP1 | selenium binding protein 1 |
| SERINC4 | serine incorporator 4 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SH2D1A | SH2 domain containing 1A |
| SH3YL1 | SH3 and SYLF domain containing 1 |
| SLC17A1 | solute carrier family 17 (organic anion transporter), member 1 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC25A25 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 |
| SNTA1 | syntrophin, alpha 1 |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) |
| SNTG2 | syntrophin, gamma 2 |
| SP6 | Sp6 transcription factor |
| ST8SIA1 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 |
| STK17B | serine/threonine kinase 17b |
| STK35 | serine/threonine kinase 35 |
| STRA6 | stimulated by retinoic acid 6 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SYNPO2 | synaptopodin 2 |
| TAOK3 | TAO kinase 3 |
| TCP11 | t-complex 11, testis-specific |
| TMEM218 | transmembrane protein 218 |
| TMEM229B | transmembrane protein 229B |
| TMEM27 | transmembrane protein 27 |
| TMEM35 | transmembrane protein 35 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRAFD1 | TRAF-type zinc finger domain containing 1 |
| TTC39C | tetratricopeptide repeat domain 39C |
| UBTD1 | ubiquitin domain containing 1 |
| UBXN11 | UBX domain protein 11 |
| VTN | vitronectin |
| WDR31 | WD repeat domain 31 |
| WDR78 | WD repeat domain 78 |
| WISP1 | WNT1 inducible signaling pathway protein 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| ZDHHC12 | zinc finger, DHHC-type containing 12 |
| ZFP57 | ZFP57 zinc finger protein |
| Symbol | Name |
|---|---|
| ACBD6 | acyl-CoA binding domain containing 6 |
| ACSS1 | acyl-CoA synthetase short-chain family member 1 |
| ANXA2 | annexin A2 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| BCL3 | B-cell CLL/lymphoma 3 |
| C1QC | complement component 1, q subcomponent, C chain |
| C1QTNF6 | C1q and tumor necrosis factor related protein 6 |
| CADPS2 | Ca++-dependent secretion activator 2 |
| CALCA | calcitonin-related polypeptide alpha |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CAPN12 | calpain 12 |
| CCKBR | cholecystokinin B receptor |
| CD44 | CD44 molecule (Indian blood group) |
| CDH20 | cadherin 20, type 2 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CHRNB4 | cholinergic receptor, nicotinic, beta 4 (neuronal) |
| CLRN3 | clarin 3 |
| COL16A1 | collagen, type XVI, alpha 1 |
| COL4A2 | collagen, type IV, alpha 2 |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CSN3 | casein kappa |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 |
| DUSP16 | dual specificity phosphatase 16 |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FABP7 | fatty acid binding protein 7, brain |
| FKBP5 | FK506 binding protein 5 |
| FMN1 | formin 1 |
| FMO3 | flavin containing monooxygenase 3 |
| FOXD1 | forkhead box D1 |
| FRMD6 | FERM domain containing 6 |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| GDAP1L1 | ganglioside induced differentiation associated protein 1-like 1 |
| GFAP | glial fibrillary acidic protein |
| GHRH | growth hormone releasing hormone |
| GLIPR2 | GLI pathogenesis-related 2 |
| GLYCAM1 | glycosylation dependent cell adhesion molecule 1 (pseudogene) |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GULOP | gulonolactone (L-) oxidase, pseudogene |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HNF1A | HNF1 homeobox A |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
| INHBB | inhibin, beta B |
| INSM1 | insulinoma-associated 1 |
| INSM2 | insulinoma-associated 2 |
| IRF5 | interferon regulatory factor 5 |
| JAM3 | junctional adhesion molecule 3 |
| JUNB | jun B proto-oncogene |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KLF10 | Kruppel-like factor 10 |
| KSR1 | kinase suppressor of ras 1 |
| LAD1 | ladinin 1 |
| LDB1 | LIM domain binding 1 |
| LECT1 | leukocyte cell derived chemotaxin 1 |
| LIN28A | lin-28 homolog A (C. elegans) |
| LIX1 | Lix1 homolog (chicken) |
| LRRC4 | leucine rich repeat containing 4 |
| LXN | latexin |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MFSD4 | major facilitator superfamily domain containing 4 |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MYOCD | myocardin |
| MYOZ1 | myozenin 1 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OSMR | oncostatin M receptor |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PCSK2 | proprotein convertase subtilisin/kexin type 2 |
| PHOSPHO1 | phosphatase, orphan 1 |
| PHOX2B | paired-like homeobox 2b |
| PLAT | plasminogen activator, tissue |
| PLEC | plectin |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PPP1R14A | protein phosphatase 1, regulatory (inhibitor) subunit 14A |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PTER | phosphotriesterase related |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RAI14 | retinoic acid induced 14 |
| RBP4 | retinol binding protein 4, plasma |
| RGL3 | ral guanine nucleotide dissociation stimulator-like 3 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RXRG | retinoid X receptor, gamma |
| S100A16 | S100 calcium binding protein A16 |
| S100A6 | S100 calcium binding protein A6 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
| SEMA5B | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
| SH3BP4 | SH3-domain binding protein 4 |
| SKAP2 | src kinase associated phosphoprotein 2 |
| SLC22A7 | solute carrier family 22 (organic anion transporter), member 7 |
| SLC26A4 | solute carrier family 26 (anion exchanger), member 4 |
| SMOC2 | SPARC related modular calcium binding 2 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SOCS3 | suppressor of cytokine signaling 3 |
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) |
| SPSB2 | splA/ryanodine receptor domain and SOCS box containing 2 |
| ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 |
| STEAP4 | STEAP family member 4 |
| TAGLN2 | transgelin 2 |
| TCTE3 | t-complex-associated-testis-expressed 3 |
| TECTA | tectorin alpha |
| TGM2 | transglutaminase 2 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TMEM176A | transmembrane protein 176A |
| TMOD1 | tropomodulin 1 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TNNC2 | troponin C type 2 (fast) |
| TRIM13 | tripartite motif containing 13 |
| TRPC3 | transient receptor potential cation channel, subfamily C, member 3 |
| TUBB6 | tubulin, beta 6 class V |
| WWC1 | WW and C2 domain containing 1 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF474 | zinc finger protein 474 |
