| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | colony stimulating factor 1 receptor|The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] (NCBI Entrez Gene Database, 1436) |
| External Link | https://ncbi.nlm.nih.gov/gene/1436 |
| Similar Terms | |
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499 genes differentially expressed following the CSF1R gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | 0.020199 |
| LCN2 | lipocalin 2 | 0.0144127 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.0141248 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.0139253 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.0131009 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.0125486 |
| MSLN | mesothelin | 0.0116925 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.0116861 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.0115729 |
| PLK2 | polo-like kinase 2 | 0.0115349 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.0115232 |
| AMOTL2 | angiomotin like 2 | 0.0115232 |
| TUBA4A | tubulin, alpha 4a | 0.0112025 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0111966 |
| CDA | cytidine deaminase | 0.0110931 |
| FOLR1 | folate receptor 1 (adult) | 0.0110039 |
| ECM1 | extracellular matrix protein 1 | 0.0108278 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0103392 |
| KLK11 | kallikrein-related peptidase 11 | 0.0103117 |
| PEG10 | paternally expressed 10 | 0.0102558 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00997911 |
| G0S2 | G0/G1 switch 2 | 0.00997086 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00995738 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0099372 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00981938 |
| S100A12 | S100 calcium binding protein A12 | 0.0097342 |
| KLK10 | kallikrein-related peptidase 10 | 0.00970668 |
| BST2 | bone marrow stromal cell antigen 2 | 0.009342 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.0092575 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00919871 |
| CLC | Charcot-Leyden crystal galectin | 0.009111 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00905943 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00905751 |
| BEX4 | brain expressed, X-linked 4 | 0.00899686 |
| IPO13 | importin 13 | 0.00896956 |
| MMP1 | matrix metallopeptidase 1 | 0.00891375 |
| ANXA3 | annexin A3 | 0.00889959 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.00888904 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00887254 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.008695 |
| MID1IP1 | MID1 interacting protein 1 | 0.008673 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00866427 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00859886 |
| PLXNC1 | plexin C1 | 0.00859132 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00857993 |
| PXDN | peroxidasin | 0.00855153 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00852601 |
| MGLL | monoglyceride lipase | 0.0084192 |
| PDGFC | platelet derived growth factor C | 0.00836283 |
| WT1 | Wilms tumor 1 | 0.0083228 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00829885 |
| SCG5 | secretogranin V | 0.00824688 |
| ELANE | elastase, neutrophil expressed | 0.00818849 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.0081666 |
| PRSS3 | protease, serine, 3 | 0.00805792 |
| RHOD | ras homolog family member D | 0.00804702 |
| EPHA2 | EPH receptor A2 | 0.00801648 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00796526 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00794594 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.0078829 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 0.00788151 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | 0.00785331 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) | 0.00785322 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.00783569 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.00777264 |
| EGR1 | early growth response 1 | 0.00775439 |
| KLK5 | kallikrein-related peptidase 5 | 0.00775101 |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) | 0.00773798 |
| TGFB1 | transforming growth factor, beta 1 | 0.00770381 |
| BICC1 | BicC family RNA binding protein 1 | 0.00766387 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.00765793 |
| PFKM | phosphofructokinase, muscle | 0.00760997 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00759851 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00756997 |
| TGM1 | transglutaminase 1 | 0.00752825 |
| PLBD1 | phospholipase B domain containing 1 | 0.00750118 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | 0.00748723 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.00743811 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0074323 |
| SMAD7 | SMAD family member 7 | 0.00738445 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00735255 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.00734642 |
| NELL1 | NEL-like 1 (chicken) | 0.0073439 |
| HTRA1 | HtrA serine peptidase 1 | 0.00733096 |
| GLS | glutaminase | 0.0073302 |
| FN1 | fibronectin 1 | 0.00732426 |
| GOLM1 | golgi membrane protein 1 | 0.00732223 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00729314 |
| AGRN | agrin | 0.00729235 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.00725068 |
| MAGED1 | melanoma antigen family D1 | 0.00719156 |
| ACTN4 | actinin, alpha 4 | 0.00717305 |
| XIC | X chromosome inactivation center | 0.00717229 |
| BGN | biglycan | 0.00717118 |
| BTG2 | BTG family, member 2 | 0.00713705 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00712154 |
| PRKCI | protein kinase C, iota | 0.00709641 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00707643 |
| GAB2 | GRB2-associated binding protein 2 | 0.00707107 |
| PLXNB2 | plexin B2 | 0.00706026 |
| S100A11 | S100 calcium binding protein A11 | 0.00700868 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00700095 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.0070004 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.00699232 |
| CTSA | cathepsin A | 0.00697384 |
| CA2 | carbonic anhydrase II | 0.00694757 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00694724 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00693973 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | 0.00692091 |
| CFB | complement factor B | 0.00691848 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.00690787 |
| IL32 | interleukin 32 | 0.00687631 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.00686452 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00685531 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 0.00685078 |
| MAP7D1 | MAP7 domain containing 1 | 0.00683155 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.00681802 |
| MMP2 | matrix metallopeptidase 2 | 0.00681716 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | 0.00681322 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta | 0.0068048 |
| EGR2 | early growth response 2 | 0.00680409 |
| HOMER3 | homer scaffolding protein 3 | 0.00675027 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00674883 |
| GSTP1 | glutathione S-transferase pi 1 | 0.0067391 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00673766 |
| NXN | nucleoredoxin | 0.00673384 |
| EPS8L1 | EPS8-like 1 | 0.00672757 |
| PILRB | paired immunoglobin-like type 2 receptor beta | 0.00669191 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.00667342 |
| STK38 | serine/threonine kinase 38 | 0.00666811 |
| FAM111A | family with sequence similarity 111, member A | 0.00666543 |
| MIR22HG | MIR22 host gene | 0.00665324 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | 0.00663403 |
| DOCK9 | dedicator of cytokinesis 9 | 0.00660226 |
| RNF167 | ring finger protein 167 | 0.00659676 |
| FAM50A | family with sequence similarity 50, member A | 0.00658818 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 | 0.00656823 |
| LAMB3 | laminin, beta 3 | 0.00656662 |
| VNN1 | vanin 1 | 0.00654417 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.00653896 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 | 0.00653575 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.00652345 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.00651642 |
| GNAS | GNAS complex locus | 0.00651451 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00649698 |
| AURKB | aurora kinase B | 0.00649221 |
| STC2 | stanniocalcin 2 | 0.00647886 |
| CD70 | CD70 molecule | 0.0064636 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.00646101 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.00644168 |
| S100A4 | S100 calcium binding protein A4 | 0.00642712 |
| INAVA | innate immunity activator | 0.00642142 |
| PKM | pyruvate kinase, muscle | 0.0064158 |
| GPX3 | glutathione peroxidase 3 | 0.00639765 |
| RAB5IF | RAB5 interacting factor | 0.0063916 |
| MNT | MAX network transcriptional repressor | 0.00638572 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00637043 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | 0.00636623 |
| CTSG | cathepsin G | 0.00635202 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00635119 |
| COL9A2 | collagen, type IX, alpha 2 | 0.00633675 |
| BRD4 | bromodomain containing 4 | 0.00631895 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | 0.00630348 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.00628808 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.00628475 |
| SST | somatostatin | 0.00627585 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.00625821 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 | 0.00623954 |
| H1-2 | H1.2 linker histone, cluster member | 0.00623779 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.00622959 |
| TUG1 | taurine up-regulated 1 (non-protein coding) | 0.00621001 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.00619746 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.00618562 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00616863 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | 0.0061645 |
| HBD | hemoglobin, delta | 0.00611983 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00610448 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00608906 |
| C9ORF3 | chromosome 9 open reading frame 3 | 0.0060859 |
| ATG2A | autophagy related 2A | 0.00607882 |
| AZU1 | azurocidin 1 | 0.006074 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.00606558 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.00605859 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.0060511 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.00600445 |
| NPIPA1 | nuclear pore complex interacting protein family, member A1 | 0.00599632 |
| CCNE1 | cyclin E1 | 0.00597283 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 0.00596312 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00593909 |
| G6PD | glucose-6-phosphate dehydrogenase | 0.00592767 |
| MICALL2 | MICAL-like 2 | 0.00592573 |
| COL16A1 | collagen, type XVI, alpha 1 | 0.00591434 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00591132 |
| THBS2 | thrombospondin 2 | 0.00590915 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | 0.00590886 |
| CTSE | cathepsin E | 0.00590317 |
| HMOX1 | heme oxygenase 1 | 0.00589536 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00589414 |
| CTSV | cathepsin V | 0.00588792 |
| EHD2 | EH-domain containing 2 | 0.00588681 |
| ATF3 | activating transcription factor 3 | 0.00588384 |
| TNS1 | tensin 1 | 0.00588226 |
| IGF2R | insulin-like growth factor 2 receptor | 0.00588021 |
| NOP2 | NOP2 nucleolar protein | 0.00585748 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.00585271 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | 0.00582768 |
| KRT18 | keratin 18, type I | 0.00582738 |
| SPATA20 | spermatogenesis associated 20 | 0.00580712 |
| FAM193A | family with sequence similarity 193, member A | 0.00579748 |
| BMP2 | bone morphogenetic protein 2 | 0.00578712 |
| RBM47 | RNA binding motif protein 47 | 0.00578657 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.00578585 |
| LAMA5 | laminin, alpha 5 | 0.00575691 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0057525 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.00573093 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | 0.00572676 |
| ZSWIM8 | zinc finger, SWIM-type containing 8 | 0.00569979 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00568944 |
| REC8 | REC8 meiotic recombination protein | 0.00568056 |
| FRMD4B | FERM domain containing 4B | 0.00567836 |
| PRPF3 | pre-mRNA processing factor 3 | 0.00566801 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00565386 |
| EDRF1 | erythroid differentiation regulatory factor 1 | 0.00564665 |
| MMP7 | matrix metallopeptidase 7 | 0.00563147 |
| CRYAB | crystallin, alpha B | 0.00563016 |
| SC5D | sterol-C5-desaturase | 0.00562837 |
| DUSP5 | dual specificity phosphatase 5 | 0.00562339 |
| NKTR | natural killer cell triggering receptor | 0.00561654 |
| MINK1 | misshapen-like kinase 1 | 0.00560822 |
| EHD1 | EH-domain containing 1 | 0.00560678 |
| ZNF83 | zinc finger protein 83 | 0.00560325 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00558923 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.00558485 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00558118 |
| FZD2 | frizzled class receptor 2 | 0.00557707 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | 0.00557438 |
| CDV3 | CDV3 homolog (mouse) | 0.00557341 |
| SLTM | SAFB-like, transcription modulator | 0.00555525 |
| PTK2B | protein tyrosine kinase 2 beta | 0.00553306 |
| TMEM147 | transmembrane protein 147 | 0.00553096 |
| PAM | peptidylglycine alpha-amidating monooxygenase | 0.00552942 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.00552772 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | 0.00552564 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.00551946 |
| DEFB1 | defensin, beta 1 | 0.00551142 |
| ORMDL2 | ORMDL sphingolipid biosynthesis regulator 2 | 0.00550811 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0055071 |
| ESR1 | estrogen receptor 1 | 0.00550131 |
| NPC1 | Niemann-Pick disease, type C1 | 0.00549869 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.00548758 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GLUL | glutamate-ammonia ligase | -0.0143977 |
| FCGBP | Fc fragment of IgG binding protein | -0.0133624 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.0132302 |
| OLFM1 | olfactomedin 1 | -0.0131998 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.0127709 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.012459 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0124059 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.0123387 |
| MMP12 | matrix metallopeptidase 12 | -0.0120368 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0119775 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0114474 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0113015 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0112405 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.011098 |
| SDC2 | syndecan 2 | -0.011082 |
| FABP7 | fatty acid binding protein 7, brain | -0.0105611 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.0101605 |
| NEBL | nebulette | -0.0100404 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.010035 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0100042 |
| MYBPC1 | myosin binding protein C, slow type | -0.00996703 |
| VSNL1 | visinin-like 1 | -0.00987906 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00986997 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00986566 |
| S100A7 | S100 calcium binding protein A7 | -0.00978228 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.00978069 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00978014 |
| KRT5 | keratin 5, type II | -0.00968822 |
| CLDN8 | claudin 8 | -0.00968767 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -0.0096835 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00946036 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0093941 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00935941 |
| GPM6A | glycoprotein M6A | -0.00925567 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00915195 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00909694 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | -0.00908959 |
| RBBP4 | retinoblastoma binding protein 4 | -0.00899081 |
| PIR | pirin (iron-binding nuclear protein) | -0.00894538 |
| CLU | clusterin | -0.00885823 |
| HNMT | histamine N-methyltransferase | -0.00879868 |
| DIO2 | deiodinase, iodothyronine, type II | -0.00875463 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00873938 |
| TNC | tenascin C | -0.0087109 |
| IQCG | IQ motif containing G | -0.00870232 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00862769 |
| CSTA | cystatin A (stefin A) | -0.00858846 |
| DMD | dystrophin | -0.00854252 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.00847603 |
| AQP4 | aquaporin 4 | -0.00840698 |
| TMEM14A | transmembrane protein 14A | -0.00839008 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00837487 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | -0.00835754 |
| MAP7 | microtubule-associated protein 7 | -0.00831933 |
| NDRG2 | NDRG family member 2 | -0.00828383 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00826033 |
| METTL7A | methyltransferase like 7A | -0.00820941 |
| MSX1 | msh homeobox 1 | -0.00820276 |
| F12 | coagulation factor XII (Hageman factor) | -0.00820109 |
| IRF6 | interferon regulatory factor 6 | -0.00819585 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.00815512 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00815484 |
| PLPP3 | phospholipid phosphatase 3 | -0.00810569 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00805945 |
| PIPOX | pipecolic acid oxidase | -0.00799894 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00798335 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00791011 |
| SATB2 | SATB homeobox 2 | -0.00787676 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00779672 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.00774979 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.00768431 |
| COG7 | component of oligomeric golgi complex 7 | -0.00764533 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00762577 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.007599 |
| OPHN1 | oligophrenin 1 | -0.0075815 |
| GPM6B | glycoprotein M6B | -0.00754637 |
| SYT1 | synaptotagmin I | -0.00750262 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00747911 |
| DAXX | death-domain associated protein | -0.00747524 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00745888 |
| PIP | prolactin-induced protein | -0.00745347 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00740289 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00734875 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00727518 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 | -0.00723493 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.00722074 |
| RCAN1 | regulator of calcineurin 1 | -0.00718004 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.00717473 |
| NES | nestin | -0.00714329 |
| CHN1 | chimerin 1 | -0.00713907 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.007121 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00709744 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00704314 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -0.00701724 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00701534 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00699175 |
| HMGB2 | high mobility group box 2 | -0.00695567 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00695483 |
| A2M | alpha-2-macroglobulin | -0.0069274 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00690709 |
| ADORA2B | adenosine A2b receptor | -0.0068833 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00687499 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.00684104 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | -0.00679502 |
| BAALC | brain and acute leukemia, cytoplasmic | -0.00678775 |
| CLCA4 | chloride channel accessory 4 | -0.00677208 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | -0.00674906 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00674312 |
| KIAA0226L | KIAA0226-like | -0.00673896 |
| TFF1 | trefoil factor 1 | -0.00671197 |
| COG5 | component of oligomeric golgi complex 5 | -0.00670849 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | -0.00670516 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | -0.0067046 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0066723 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | -0.00665517 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 | -0.00665208 |
| APOC2 | apolipoprotein C-II | -0.00663054 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00660421 |
| TOX3 | TOX high mobility group box family member 3 | -0.00659289 |
| GPX2 | glutathione peroxidase 2 | -0.00658395 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00658269 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00657112 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00653774 |
| ATG5 | autophagy related 5 | -0.00651596 |
| HAT1 | histone acetyltransferase 1 | -0.0064787 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | -0.00647631 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00646951 |
| TYRP1 | tyrosinase-related protein 1 | -0.00646612 |
| INSM1 | insulinoma-associated 1 | -0.00645205 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -0.00644222 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | -0.00642382 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | -0.00641261 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 | -0.00639106 |
| TMEM100 | transmembrane protein 100 | -0.00637531 |
| IL17RB | interleukin 17 receptor B | -0.00637312 |
| EDNRB | endothelin receptor type B | -0.00636056 |
| S100B | S100 calcium binding protein B | -0.0063567 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 | -0.00632636 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.00630942 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00626183 |
| C9ORF91 | chromosome 9 open reading frame 91 | -0.00624431 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.00623191 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 | -0.006227 |
| CCNA2 | cyclin A2 | -0.00621707 |
| QRSL1 | glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 | -0.00618798 |
| PDLIM1 | PDZ and LIM domain 1 | -0.00617771 |
| PLP1 | proteolipid protein 1 | -0.00617682 |
| LYVE1 | lymphatic vessel endothelial hyaluronan receptor 1 | -0.00616977 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | -0.00615509 |
| SLC6A1 | solute carrier family 6 (neurotransmitter transporter), member 1 | -0.00615508 |
| NXT2 | nuclear transport factor 2-like export factor 2 | -0.00614755 |
| CHI3L2 | chitinase 3-like 2 | -0.00613366 |
| GLUD2 | glutamate dehydrogenase 2 | -0.00612908 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00612174 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.00611577 |
| MYLK | myosin light chain kinase | -0.0060991 |
| SELE | selectin E | -0.00609678 |
| FABP1 | fatty acid binding protein 1, liver | -0.00609528 |
| SOD1 | superoxide dismutase 1, soluble | -0.00609503 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00608435 |
| ZNF226 | zinc finger protein 226 | -0.00607821 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.00607477 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00606066 |
| LYRM4 | LYR motif containing 4 | -0.00604765 |
| TSPAN31 | tetraspanin 31 | -0.00603382 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00602565 |
| CLCA1 | chloride channel accessory 1 | -0.00601179 |
| EPAS1 | endothelial PAS domain protein 1 | -0.00600953 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00600388 |
| PBK | PDZ binding kinase | -0.00597589 |
| FKBP5 | FK506 binding protein 5 | -0.00595748 |
| HPR | haptoglobin-related protein | -0.00594007 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | -0.00592702 |
| GFAP | glial fibrillary acidic protein | -0.00592656 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | -0.00592512 |
| FMO3 | flavin containing monooxygenase 3 | -0.00591585 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00589425 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00588826 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 | -0.00586456 |
| GSTO1 | glutathione S-transferase omega 1 | -0.00586004 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00585311 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.00584173 |
| IFT52 | intraflagellar transport 52 | -0.00583839 |
| ACTR6 | ARP6 actin-related protein 6 homolog (yeast) | -0.00582595 |
| RHOA | ras homolog family member A | -0.00582164 |
| KRT13 | keratin 13, type I | -0.00580119 |
| CD163 | CD163 molecule | -0.00577772 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -0.00575257 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00572727 |
| SORD | sorbitol dehydrogenase | -0.00571733 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00571482 |
| CPQ | carboxypeptidase Q | -0.00571287 |
| AQP9 | aquaporin 9 | -0.00570689 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00570619 |
| RELN | reelin | -0.00569937 |
| TXNIP | thioredoxin interacting protein | -0.00569774 |
| SCAMP1 | secretory carrier membrane protein 1 | -0.00569719 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00569675 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00569133 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00568782 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | -0.00568646 |
| FERMT2 | fermitin family member 2 | -0.00568527 |
| BCL2A1 | BCL2-related protein A1 | -0.00568339 |
| PMP2 | peripheral myelin protein 2 | -0.00566653 |
| CHPT1 | choline phosphotransferase 1 | -0.00566295 |
| REG3A | regenerating islet-derived 3 alpha | -0.00565279 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | -0.00564322 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.005641 |
| CDO1 | cysteine dioxygenase type 1 | -0.00563897 |
| SERPINC1 | serpin peptidase inhibitor, clade C (antithrombin), member 1 | -0.00563749 |
| TSC22D1 | TSC22 domain family, member 1 | -0.00562942 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.00561164 |
| ALPL | alkaline phosphatase, liver/bone/kidney | -0.00560538 |
| CHRDL1 | chordin-like 1 | -0.00558717 |
| GLUD1 | glutamate dehydrogenase 1 | -0.00556422 |
| NIPSNAP2 | nipsnap homolog 2 | -0.00556164 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.00556022 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.00555754 |
| FMO4 | flavin containing monooxygenase 4 | -0.00555338 |
| ZNF652 | zinc finger protein 652 | -0.0055486 |
| ANXA6 | annexin A6 | -0.00553645 |
| CNN3 | calponin 3, acidic | -0.00553144 |
| PGAP3 | post-GPI attachment to proteins 3 | -0.00550703 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | -0.00549712 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 | -0.00548885 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.00547681 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.00547654 |
| SLC1A2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 | -0.00546294 |
| PRDX4 | peroxiredoxin 4 | -0.00546103 |
| LGALS9 | lectin, galactoside-binding, soluble, 9 | -0.00544438 |
| CFHR2 | complement factor H-related 2 | -0.00544395 |
| NOX1 | NADPH oxidase 1 | -0.00544161 |
| CPB2 | carboxypeptidase B2 (plasma) | -0.00543863 |
| TMEM38B | transmembrane protein 38B | -0.00542622 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.00540093 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase | -0.00539797 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00539739 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00538233 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | -0.00538003 |
| PENK | proenkephalin | -0.00537935 |
| GABRB1 | gamma-aminobutyric acid (GABA) A receptor, beta 1 | -0.00537386 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00536745 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0053481 |
| SYNM | synemin, intermediate filament protein | -0.00534761 |
| MLF1 | myeloid leukemia factor 1 | -0.00533413 |
| FAR2 | fatty acyl CoA reductase 2 | -0.00532892 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) | -0.00531793 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00531 |
| IFNGR1 | interferon gamma receptor 1 | -0.00529615 |
