CSF1R Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description colony stimulating factor 1 receptor|The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] (NCBI Entrez Gene Database, 1436)
External Link http://www.ncbi.nlm.nih.gov/gene/1436
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1 substrates of the kinase CSF1R from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
CSF1R colony stimulating factor 1 receptor