CSK Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description c-src tyrosine kinase| (NCBI Entrez Gene Database, 1445)
Similar Terms
Downloads & Tools

Genes

347 genes differentially expressed following the CSK gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 3.41016
SIRPB1 signal-regulatory protein beta 1 3.41016
OR10A6 olfactory receptor, family 10, subfamily A, member 6 (gene/pseudogene) 3.41016
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 3.41016
FOLR2 folate receptor 2 (fetal) 3.41016
SIGLEC7 sialic acid binding Ig-like lectin 7 3.41016
C19ORF67 chromosome 19 open reading frame 67 3.41016
SLC23A3 solute carrier family 23, member 3 3.41016
CA6 carbonic anhydrase VI 3.41016
TCAF2 TRPM8 channel-associated factor 2 3.41016
THRSP thyroid hormone responsive 3.41016
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 3.41016
SOX18 SRY (sex determining region Y)-box 18 3.41016
NR1H4 nuclear receptor subfamily 1, group H, member 4 3.41016
COLEC10 collectin sub-family member 10 (C-type lectin) 3.41016
MS4A4E membrane-spanning 4-domains, subfamily A, member 4E 3.41016
GPR52 G protein-coupled receptor 52 3.41016
SLC26A9 solute carrier family 26 (anion exchanger), member 9 3.41016
SLC26A4 solute carrier family 26 (anion exchanger), member 4 3.41016
RXFP2 relaxin/insulin-like family peptide receptor 2 3.41016
CELF3 CUGBP, Elav-like family member 3 3.41016
IL22RA1 interleukin 22 receptor, alpha 1 3.41016
NANOS2 nanos homolog 2 (Drosophila) 3.41016
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 3.41016
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 3.41016
GRIFIN galectin-related inter-fiber protein 3.41016
SOST sclerostin 3.41016
DSPP dentin sialophosphoprotein 3.41016
ANKRD30B ankyrin repeat domain 30B 3.41016
BANF2 barrier to autointegration factor 2 3.41016
PGM5 phosphoglucomutase 5 3.41016
ZPLD1 zona pellucida-like domain containing 1 3.41016
SDSL serine dehydratase-like 3.41016
TGM6 transglutaminase 6 3.41016
IFNK interferon, kappa 3.41016
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 3.41016
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 3.41016
CRYGN crystallin, gamma N 3.41016
ACOT12 acyl-CoA thioesterase 12 3.41016
CHD5 chromodomain helicase DNA binding protein 5 3.41016
SLC39A12 solute carrier family 39 (zinc transporter), member 12 3.41016
CPLX3 complexin 3 3.41016
ASGR2 asialoglycoprotein receptor 2 3.41016
RSPH3 radial spoke 3 homolog (Chlamydomonas) 3.41016
SPHK1 sphingosine kinase 1 3.41016
SPACA5 sperm acrosome associated 5 3.41016
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) 3.41016
TEX35 testis expressed 35 3.41016
LOC107986837 uncharacterized LOC107986837 3.41016
CFAP65 cilia and flagella associated protein 65 3.41016
DEFB108B defensin, beta 108B 3.41016
GBP4 guanylate binding protein 4 3.41016
GBP2 guanylate binding protein 2, interferon-inducible 3.41016
FRG2C FSHD region gene 2 family, member C 3.41016
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 3.41016
PROZ protein Z, vitamin K-dependent plasma glycoprotein 3.41016
ASB4 ankyrin repeat and SOCS box containing 4 3.41016
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 3.41016
GATA2 GATA binding protein 2 3.41016
HTD2 hydroxyacyl-thioester dehydratase type 2 3.41016
TMEM275 transmembrane protein 275 3.41016
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 3.41016
CIMIP2C ciliary microtubule inner protein 2C 3.41016
ERLN endoregulin 3.41016
LOC124906010 uncharacterized LOC124906010 3.41016
GREP1 glycine rich extracellular protein 1 3.41016
CPHXL cytoplasmic polyadenylated homeobox like 3.41016
MEIOSIN meiosis initiator 3.41016
GSTT4 glutathione S-transferase theta 4 3.41016
KASH5 KASH domain containing 5 3.41016
PLAAT4 phospholipase A and acyltransferase 4 3.41016
PRDM7 PR domain containing 7 3.41016
CSAG1 chondrosarcoma associated gene 1 3.41016
FOSL1 FOS-like antigen 1 3.41016
CCDC13 coiled-coil domain containing 13 3.41016
RHOXF2 Rhox homeobox family, member 2 3.41016
IL12RB1 interleukin 12 receptor, beta 1 3.41016
PVRIG poliovirus receptor related immunoglobulin domain containing 3.41016
FPR1 formyl peptide receptor 1 3.41016
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 3.41016
SRPX2 sushi-repeat containing protein, X-linked 2 3.41016
GJA3 gap junction protein, alpha 3, 46kDa 3.41016
FAM187B family with sequence similarity 187, member B 3.41016
CLEC3A C-type lectin domain family 3, member A 3.41016
OR51B5 olfactory receptor, family 51, subfamily B, member 5 3.41016
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus 3.41016
BEST3 bestrophin 3 3.41016
NPIPB8 nuclear pore complex interacting protein family, member B8 3.41016
ZAR1L zygote arrest 1-like 3.41016
LRRC3C leucine rich repeat containing 3C 3.41016
PGC progastricsin (pepsinogen C) 3.41016
ADGRG1 adhesion G protein-coupled receptor G1 3.41016
OR11A1 olfactory receptor, family 11, subfamily A, member 1 3.41016
MSX2 msh homeobox 2 3.41016
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 3.41016
AGTR1 angiotensin II receptor, type 1 3.41016
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 3.41016
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 3.41016
CRYBB2 crystallin, beta B2 3.41016
CYSLTR1 cysteinyl leukotriene receptor 1 3.41016
C2CD4A C2 calcium-dependent domain containing 4A 3.41016
LCN9 lipocalin 9 3.41016
WFDC6 WAP four-disulfide core domain 6 3.41016
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 3.41016
SERINC4 serine incorporator 4 3.41016
C16ORF78 chromosome 16 open reading frame 78 3.41016
CGB2 chorionic gonadotropin, beta polypeptide 2 3.41016
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene) 3.41016
ADGRA1 adhesion G protein-coupled receptor A1 3.41016
SOWAHA sosondowah ankyrin repeat domain family member A 3.41016
MRGPRE MAS-related GPR, member E 3.41016
ERICH4 glutamate-rich 4 3.41016
CT55 cancer/testis antigen 55 3.41016
RNF112 ring finger protein 112 3.41016
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 3.41016
EDN3 endothelin 3 3.41016
NLRC5 NLR family, CARD domain containing 5 3.41016
CERKL ceramide kinase-like 3.41016
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 3.41016
MUC17 mucin 17, cell surface associated 3.41016
TSPAN19 tetraspanin 19 3.41016
FAIM2 Fas apoptotic inhibitory molecule 2 3.41016
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase 3.41016
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 3.41016
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 3.41016
OTP orthopedia homeobox 3.41016
LMX1A LIM homeobox transcription factor 1, alpha 3.41016
C10ORF105 chromosome 10 open reading frame 105 3.41016
EOMES eomesodermin 3.41016
OR13G1 olfactory receptor, family 13, subfamily G, member 1 3.41016
ORM2 orosomucoid 2 3.41016
C17ORF99 chromosome 17 open reading frame 99 3.41016
KISS1 KiSS-1 metastasis-suppressor 3.41016
CHIT1 chitinase 1 (chitotriosidase) 3.41016
FGR FGR proto-oncogene, Src family tyrosine kinase 3.41016
PIP prolactin-induced protein 3.41016
NTN5 netrin 5 3.41016
SYNGR4 synaptogyrin 4 3.41016
NOBOX NOBOX oogenesis homeobox 3.41016
LHX2 LIM homeobox 2 3.41016
GJC2 gap junction protein, gamma 2, 47kDa 3.41016
ZNF132 zinc finger protein 132 3.41016
NTSR2 neurotensin receptor 2 3.41016
PRRX1 paired related homeobox 1 3.41016
TECRL trans-2,3-enoyl-CoA reductase-like 3.41016
IL13RA2 interleukin 13 receptor, alpha 2 3.41016
WDFY4 WDFY family member 4 3.41016
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10 3.41016
STMND1 stathmin domain containing 1 3.41016
IGFL1 IGF-like family member 1 3.41016
ZNF474 zinc finger protein 474 3.41016
ZMYND10 zinc finger, MYND-type containing 10 3.41016
IL12A interleukin 12A 3.41016
ANKRD33 ankyrin repeat domain 33 3.41016
NUTM2D NUT family member 2D 3.41016
LRCOL1 leucine rich colipase-like 1 3.41016
ENDOU endonuclease, polyU-specific 3.41016
TSKS testis-specific serine kinase substrate 3.41016
SLC51B solute carrier family 51, beta subunit 3.41016
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 3.41016
PXT1 peroxisomal, testis specific 1 3.41016
AQP10 aquaporin 10 3.41016
ZBTB42 zinc finger and BTB domain containing 42 3.36885
AQP3 aquaporin 3 (Gill blood group) 3.36885
DIO1 deiodinase, iodothyronine, type I 3.36885
MYO16 myosin XVI 3.30494
ANTXR2 anthrax toxin receptor 2 3.25799
ATOSA atos homolog A 3.21362
KRTDAP keratinocyte differentiation-associated protein 3.20502
PTGFR prostaglandin F receptor (FP) 3.03927
CPNE3 copine III 3.03222
MXRA5 matrix-remodelling associated 5 2.97091
ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator 2.92574
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 2.92354
GEM GTP binding protein overexpressed in skeletal muscle 2.87619
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 2.80863
YIPF2 Yip1 domain family, member 2 2.73527
SLX4 SLX4 structure-specific endonuclease subunit 2.56431
SFMBT2 Scm-like with four mbt domains 2 2.54863
KTN1 kinectin 1 (kinesin receptor) 2.54854
MSANTD4 Myb/SANT-like DNA-binding domain containing 4 with coiled-coils 2.51046
HCLS1 hematopoietic cell-specific Lyn substrate 1 2.47156
ADAM29 ADAM metallopeptidase domain 29 2.47156
WDR93 WD repeat domain 93 2.47156
TICAM1 toll-like receptor adaptor molecule 1 2.47156
NCR1 natural cytotoxicity triggering receptor 1 2.47156
DND1 DND microRNA-mediated repression inhibitor 1 2.47156
MOG myelin oligodendrocyte glycoprotein 2.47156
INSM1 insulinoma-associated 1 2.47156
STKLD1 serine/threonine kinase-like domain containing 1 2.47156
CNTNAP4 contactin associated protein-like 4 2.47156
STAB1 stabilin 1 2.45256
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 2.45256
CHEK2 checkpoint kinase 2 2.42933
CCDC166 coiled-coil domain containing 166 2.41991
DENND6A DENN/MADD domain containing 6A 2.41334
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 2.36838
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 2.35676
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) 2.33738
C10ORF88 chromosome 10 open reading frame 88 2.31596
SORBS1 sorbin and SH3 domain containing 1 2.31596
OGA O-GlcNAcase 2.27803
ANKRD36C ankyrin repeat domain 36C 2.26859
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 2.26441
DTX1 deltex 1, E3 ubiquitin ligase 2.26351
SLIRP SRA stem-loop interacting RNA binding protein 2.25661
NCAPD3 non-SMC condensin II complex, subunit D3 2.24184
C3ORF52 chromosome 3 open reading frame 52 2.22933
DACT3 dishevelled-binding antagonist of beta-catenin 3 2.22933
ZNF493 zinc finger protein 493 2.22933
FAM76B family with sequence similarity 76, member B 2.22933
CACTIN cactin, spliceosome C complex subunit 2.22933
ZNF585B zinc finger protein 585B 2.18979
ASTN1 astrotactin 1 2.18114
KYAT3 kynurenine aminotransferase 3 2.17022
NUDCD1 NudC domain containing 1 2.16773
LIN28A lin-28 homolog A (C. elegans) 2.16083
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 2.14993
CERS1 ceramide synthase 1 2.1456
MITD1 MIT, microtubule interacting and transport, domain containing 1 2.14222
NEK10 NIMA-related kinase 10 2.1373
VEGFA vascular endothelial growth factor A 2.13673
GBA2 glucosidase, beta (bile acid) 2 2.13078
BOP1 block of proliferation 1 2.12014
RBM15B RNA binding motif protein 15B 2.08954
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa 2.08835
FBRSL1 fibrosin-like 1 2.0835
CCDC18 coiled-coil domain containing 18 2.0779
NAXD NAD(P)HX dehydratase 2.07774
ZDHHC14 zinc finger, DHHC-type containing 14 2.07774
ZHX3 zinc fingers and homeoboxes 3 2.07774
CABIN1 calcineurin binding protein 1 2.07774
FNDC11 fibronectin type III domain containing 11 2.0743
FUNDC2 FUN14 domain containing 2 2.07093
CLDN19 claudin 19 2.06566
LRRN3 leucine rich repeat neuronal 3 2.06222
DCLK1 doublecortin-like kinase 1 2.0582
MDFI MyoD family inhibitor 2.05683
RMP24 ribonuclease MRP subunit p24 2.05278
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 2.05218
SFT2D2 SFT2 domain containing 2 2.04732
MED24 mediator complex subunit 24 2.04031
EPN1 epsin 1 2.03879
DEDD2 death effector domain containing 2 2.00869
APOM apolipoprotein M 2.00623
SKI SKI proto-oncogene 2.00569

decreased expression

Symbol Name Standardized Value
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) -3.41016
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -3.41016
RPH3A rabphilin 3A -3.41016
ECM1 extracellular matrix protein 1 -3.41016
PCDH19 protocadherin 19 -3.40723
POTEJ POTE ankyrin domain family, member J -3.25799
ACSM4 acyl-CoA synthetase medium-chain family member 4 -3.25799
CD177 CD177 molecule -3.25799
GABRD gamma-aminobutyric acid (GABA) A receptor, delta -3.25799
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 -3.25799
FNDC1 fibronectin type III domain containing 1 -3.25799
MYO1A myosin IA -3.25799
LEP leptin -3.25799
ACTA1 actin, alpha 1, skeletal muscle -3.25799
PDE7B phosphodiesterase 7B -3.25799
PCDH8 protocadherin 8 -3.25799
HCST hematopoietic cell signal transducer -3.25799
MYBPC1 myosin binding protein C, slow type -3.25799
COL15A1 collagen, type XV, alpha 1 -3.25799
SLC46A3 solute carrier family 46, member 3 -3.25799
ACTG2 actin, gamma 2, smooth muscle, enteric -3.25799
RNF39 ring finger protein 39 -3.25799
BRDT bromodomain, testis-specific -3.25799
CA5A carbonic anhydrase VA, mitochondrial -3.25799
PEAK3 PEAK family member 3 -3.25799
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.25799
AKNAD1 AKNA domain containing 1 -3.25799
DEFB131B defensin beta 131B -3.25799
GOLGA6B golgin A6 family, member B -3.25799
EFCC1 EF-hand and coiled-coil domain containing 1 -3.25799
ZC3H11C zinc finger CCCH-type containing 11C -3.25799
RGCC regulator of cell cycle -3.25799
SYTL3 synaptotagmin-like 3 -3.13791
ZNF562 zinc finger protein 562 -3.04728
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -3.01245
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -3.00311
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) -2.93679
ANGEL2 angel homolog 2 (Drosophila) -2.91032
BCDIN3D BCDIN3 domain containing -2.88869
MOB3C MOB kinase activator 3C -2.80145
HPS6 Hermansky-Pudlak syndrome 6 -2.77915
TEDC1 tubulin epsilon and delta complex 1 -2.73625
GRID2 glutamate receptor, ionotropic, delta 2 -2.73527
ING5 inhibitor of growth family, member 5 -2.69519
PHC1 polyhomeotic homolog 1 (Drosophila) -2.68047
PRCD progressive rod-cone degeneration -2.65373
PDE11A phosphodiesterase 11A -2.65041
U2AF1L4 U2 small nuclear RNA auxiliary factor 1-like 4 -2.57778
TMEM132B transmembrane protein 132B -2.47486
KAT2A K(lysine) acetyltransferase 2A -2.46793
TMEM256 transmembrane protein 256 -2.4228
LCN2 lipocalin 2 -2.41457
SHISA3 shisa family member 3 -2.41457
GPR137 G protein-coupled receptor 137 -2.40335
TCEAL8 transcription elongation factor A (SII)-like 8 -2.39938
IL1R1 interleukin 1 receptor, type I -2.39804
ATP5MK ATP synthase membrane subunit k -2.3903
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 -2.37518
TRAM1L1 translocation associated membrane protein 1-like 1 -2.36838
PTH2 parathyroid hormone 2 -2.36838
DIAPH3 diaphanous-related formin 3 -2.33738
ANKRD45 ankyrin repeat domain 45 -2.3365
STX17 syntaxin 17 -2.31007
GTSE1 G-2 and S-phase expressed 1 -2.28761
ZNF48 zinc finger protein 48 -2.28102
MEA1 male-enhanced antigen 1 -2.27803
UBAP1 ubiquitin associated protein 1 -2.22933
ANKRD31 ankyrin repeat domain 31 -2.22933
C11ORF24 chromosome 11 open reading frame 24 -2.22933
A4GALT alpha 1,4-galactosyltransferase -2.22933
PEA15 phosphoprotein enriched in astrocytes 15 -2.22258
NUBP1 nucleotide binding protein 1 -2.18949
ZC3H15 zinc finger CCCH-type containing 15 -2.18114
NME5 NME/NM23 family member 5 -2.18001
IDE insulin-degrading enzyme -2.16773
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -2.16207
WASHC2C WASH complex subunit 2C -2.14602
MPPED1 metallophosphoesterase domain containing 1 -2.1456
COPS8 COP9 signalosome subunit 8 -2.13126
RER1 retention in endoplasmic reticulum sorting receptor 1 -2.12492
DCBLD1 discoidin, CUB and LCCL domain containing 1 -2.12492
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 -2.12014
PRPH2 peripherin 2 (retinal degeneration, slow) -2.12014
TNC tenascin C -2.12014
KLHL34 kelch-like family member 34 -2.12014
NDE1 nudE neurodevelopment protein 1 -2.11786
ZNF93 zinc finger protein 93 -2.10911
WTAP Wilms tumor 1 associated protein -2.10666
LYRM7 LYR motif containing 7 -2.07774
EIF1 eukaryotic translation initiation factor 1 -2.07774
SAXO6 stabilizer of axonemal microtubules 6 -2.07774
SMIM24 small integral membrane protein 24 -2.0675
TOP3A topoisomerase (DNA) III alpha -2.06448
NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1 -2.05425
NKD1 naked cuticle homolog 1 (Drosophila) -2.04644
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q -2.03879
SH2B3 SH2B adaptor protein 3 -2.03879
UBXN4 UBX domain protein 4 -2.01317
ZSWIM1 zinc finger, SWIM-type containing 1 -2.01076
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled -2.01076
TMEM164 transmembrane protein 164 -2.01076