CSNK2A1 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description casein kinase 2, alpha 1 polypeptide|Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythm. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene. [provided by RefSeq, Jul 2014] (NCBI Entrez Gene Database, 1457)
External Link http://www.ncbi.nlm.nih.gov/gene/1457
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Genes

248 substrates of the kinase CSNK2A1 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ACE angiotensin I converting enzyme
AIP aryl hydrocarbon receptor interacting protein
AKT1 v-akt murine thymoma viral oncogene homolog 1
AMPH amphiphysin
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
APOE apolipoprotein E
ARNT aryl hydrocarbon receptor nuclear translocator
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARRB2 arrestin, beta 2
ASCL1 achaete-scute family bHLH transcription factor 1
ATF1 activating transcription factor 1
ATXN3 ataxin 3
BCAM basal cell adhesion molecule (Lutheran blood group)
BID BH3 interacting domain death agonist
BIK BCL2-interacting killer (apoptosis-inducing)
BIRC5 baculoviral IAP repeat containing 5
BRCA1 breast cancer 1, early onset
C1R complement component 1, r subcomponent
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CARD9 caspase recruitment domain family, member 9
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CASQ2 calsequestrin 2 (cardiac muscle)
CAV2 caveolin 2
CBX1 chromobox homolog 1
CBX5 chromobox homolog 5
CCNH cyclin H
CD5 CD5 molecule
CD6 CD6 molecule
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDC27 cell division cycle 27
CDC34 cell division cycle 34
CDC37 cell division cycle 37
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK1 cyclin-dependent kinase 1
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLIP1 CAP-GLY domain containing linker protein 1
COL17A1 collagen, type XVII, alpha 1
CORO1C coronin, actin binding protein, 1C
CREB1 cAMP responsive element binding protein 1
CREM cAMP responsive element modulator
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2B casein kinase 2, beta polypeptide
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUX1 cut-like homeobox 1
DAXX death-domain associated protein
DDIT3 DNA-damage-inducible transcript 3
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DMBT1 deleted in malignant brain tumors 1
DZIP1 DAZ interacting zinc finger protein 1
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF3J eukaryotic translation initiation factor 3, subunit J
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EIF5 eukaryotic translation initiation factor 5
ERCC3 excision repair cross-complementation group 3
ESR1 estrogen receptor 1
EXOSC9 exosome component 9
F5 coagulation factor V (proaccelerin, labile factor)
FAF1 Fas (TNFRSF6) associated factor 1
FGA fibrinogen alpha chain
FMR1 fragile X mental retardation 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FURIN furin (paired basic amino acid cleaving enzyme)
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GAP43 growth associated protein 43
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GMFB glia maturation factor, beta
GMNN geminin, DNA replication inhibitor
GPI glucose-6-phosphate isomerase
HCLS1 hematopoietic cell-specific Lyn substrate 1
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HDAC6 histone deacetylase 6
HES6 hes family bHLH transcription factor 6
HHEX hematopoietically expressed homeobox
HMGA2 high mobility group AT-hook 2
HMGN1 high mobility group nucleosome binding domain 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HOXB6 homeobox B6
HOXB7 homeobox B7
HSF1 heat shock transcription factor 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPH1 heat shock 105kDa/110kDa protein 1
IFI16 interferon, gamma-inducible protein 16
IGF2R insulin-like growth factor 2 receptor
IGFBP1 insulin-like growth factor binding protein 1
IGFBP3 insulin-like growth factor binding protein 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL16 interleukin 16
IP6K2 inositol hexakisphosphate kinase 2
ITCH itchy E3 ubiquitin protein ligase
JUN jun proto-oncogene
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KLF1 Kruppel-like factor 1 (erythroid)
L1CAM L1 cell adhesion molecule
LEF1 lymphoid enhancer-binding factor 1
LIG1 ligase I, DNA, ATP-dependent
LRP6 low density lipoprotein receptor-related protein 6
M6PR mannose-6-phosphate receptor (cation dependent)
MAPK1 mitogen-activated protein kinase 1
MAPK9 mitogen-activated protein kinase 9
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MAX MYC associated factor X
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MCM2 minichromosome maintenance complex component 2
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECOM MDS1 and EVI1 complex locus
MEF2A myocyte enhancer factor 2A
MEF2C myocyte enhancer factor 2C
MME membrane metallo-endopeptidase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MUSK muscle, skeletal, receptor tyrosine kinase
MYB v-myb avian myeloblastosis viral oncogene homolog
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYBPC3 myosin binding protein C, cardiac
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYF5 myogenic factor 5
MYH10 myosin, heavy chain 10, non-muscle
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYH9 myosin, heavy chain 9, non-muscle
MYL12B myosin, light chain 12B, regulatory
NCAPH non-SMC condensin I complex, subunit H
NCF1 neutrophil cytosolic factor 1
NCOA2 nuclear receptor coactivator 2
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NFE2L1 nuclear factor, erythroid 2-like 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NKX2-5 NK2 homeobox 5
NOTCH1 notch 1
NPHP1 nephronophthisis 1 (juvenile)
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
OAZ2 ornithine decarboxylase antizyme 2
OCLN occludin
ODC1 ornithine decarboxylase 1
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
PACS1 phosphofurin acidic cluster sorting protein 1
PACSIN1 protein kinase C and casein kinase substrate in neurons 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAWR PRKC, apoptosis, WT1, regulator
PAX3 paired box 3
PDCD5 programmed cell death 5
PDCL phosducin-like
PDIA6 protein disulfide isomerase family A, member 6
PDX1 pancreatic and duodenal homeobox 1
PEA15 phosphoprotein enriched in astrocytes 15
PER2 period circadian clock 2
PGR progesterone receptor
PIAS1 protein inhibitor of activated STAT, 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLD1 phospholipase D1, phosphatidylcholine-specific
PML promyelocytic leukemia
PPARG peroxisome proliferator-activated receptor gamma
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PRPF3 pre-mRNA processing factor 3
PSEN2 presenilin 2
PTEN phosphatase and tensin homolog
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTPRC protein tyrosine phosphatase, receptor type, C
RAD1 RAD1 checkpoint DNA exonuclease
RAD51 RAD51 recombinase
RAD9A RAD9 homolog A (S. pombe)
RANGAP1 Ran GTPase activating protein 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGS19 regulator of G-protein signaling 19
RNF7 ring finger protein 7
RNPS1 RNA binding protein S1, serine-rich domain
RPS5 ribosomal protein S5
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RRAD Ras-related associated with diabetes
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPT2 septin 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SET SET nuclear proto-oncogene
SHOX short stature homeobox
SIRT1 sirtuin 1
SLBP stem-loop binding protein
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLITRK1 SLIT and NTRK-like family, member 1
SMC3 structural maintenance of chromosomes 3
SNAI1 snail family zinc finger 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPI1 Spi-1 proto-oncogene
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRPK1 SRSF protein kinase 1
SSB Sjogren syndrome antigen B (autoantigen La)
SSRP1 structure specific recognition protein 1
STARD10 StAR-related lipid transfer (START) domain containing 10
STAT1 signal transducer and activator of transcription 1, 91kDa
STC2 stanniocalcin 2
STIP1 stress-induced phosphoprotein 1
STX1A syntaxin 1A (brain)
TARDBP TAR DNA binding protein
TELO2 telomere maintenance 2
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THRA thyroid hormone receptor, alpha
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TOP1 topoisomerase (DNA) I
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TSPY1 testis specific protein, Y-linked 1
TTI1 TELO2 interacting protein 1
TWIST1 twist family bHLH transcription factor 1
TYMS thymidylate synthetase
UBE2R2 ubiquitin-conjugating enzyme E2R 2
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VAMP4 vesicle-associated membrane protein 4
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VTN vitronectin
WAS Wiskott-Aldrich syndrome
WASF2 WAS protein family, member 2
WEE1 WEE1 G2 checkpoint kinase
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YY1 YY1 transcription factor