| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/CSR_LATE_UP.V1_UP |
| Similar Terms | |
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337 genes differentially expressed following the CSR_LATE_UP.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| ACTL6A | actin-like 6A |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| ALKBH7 | alkB, alkylation repair homolog 7 (E. coli) |
| ANKRD32 | ankyrin repeat domain 32 |
| ANLN | anillin, actin binding protein |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ASB6 | ankyrin repeat and SOCS box containing 6 |
| BEX1 | brain expressed, X-linked 1 |
| BIRC5 | baculoviral IAP repeat containing 5 |
| C19ORF48 | chromosome 19 open reading frame 48 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CBFB | core-binding factor, beta subunit |
| CCDC34 | coiled-coil domain containing 34 |
| CCND3 | cyclin D3 |
| CCT6P3 | chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3 |
| CDC6 | cell division cycle 6 |
| CDC7 | cell division cycle 7 |
| CDCA8 | cell division cycle associated 8 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CDK1 | cyclin-dependent kinase 1 |
| CDK5 | cyclin-dependent kinase 5 |
| CHEK2 | checkpoint kinase 2 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 |
| CKAP2 | cytoskeleton associated protein 2 |
| CLSPN | claspin |
| CMC2 | C-x(9)-C motif containing 2 |
| COPS3 | COP9 signalosome subunit 3 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CTPS1 | CTP synthase 1 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 |
| DCTPP1 | dCTP pyrophosphatase 1 |
| DIAPH3 | diaphanous-related formin 3 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) |
| DTYMK | deoxythymidylate kinase (thymidylate kinase) |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B |
| EIF5A | eukaryotic translation initiation factor 5A |
| EML1 | echinoderm microtubule associated protein like 1 |
| EXOSC9 | exosome component 9 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FAM216A | family with sequence similarity 216, member A |
| FAM83D | family with sequence similarity 83, member D |
| FANCA | Fanconi anemia, complementation group A |
| FARSA | phenylalanyl-tRNA synthetase, alpha subunit |
| FARSB | phenylalanyl-tRNA synthetase, beta subunit |
| FEN1 | flap structure-specific endonuclease 1 |
| FKBP1A | FK506 binding protein 1A, 12kDa |
| FOXM1 | forkhead box M1 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GINS3 | GINS complex subunit 3 (Psf3 homolog) |
| GMNN | geminin, DNA replication inhibitor |
| GREM2 | gremlin 2, DAN family BMP antagonist |
| GTF3C6 | general transcription factor IIIC, polypeptide 6, alpha 35kDa |
| GYS1 | glycogen synthase 1 (muscle) |
| HAT1 | histone acetyltransferase 1 |
| HAUS2 | HAUS augmin-like complex, subunit 2 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HIP1 | huntingtin interacting protein 1 |
| HMGB1 | high mobility group box 1 |
| HN1 | hematological and neurological expressed 1 |
| HYPK | huntingtin interacting protein K |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IL7R | interleukin 7 receptor |
| ILF2 | interleukin enhancer binding factor 2 |
| IMP4 | IMP4, U3 small nucleolar ribonucleoprotein |
| ITGA6 | integrin, alpha 6 |
| KATNAL1 | katanin p60 subunit A-like 1 |
| KCNC4 | potassium channel, voltage gated Shaw related subfamily C, member 4 |
| KIF1BP | KIF1 binding protein |
| KIF22 | kinesin family member 22 |
| KISS1 | KiSS-1 metastasis-suppressor |
| KRT18 | keratin 18, type I |
| KRT25 | keratin 25, type I |
| LMNB2 | lamin B2 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LYAR | Ly1 antibody reactive |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 |
| MAZ | MYC-associated zinc finger protein (purine-binding transcription factor) |
| MBL2 | mannose-binding lectin (protein C) 2, soluble |
| MCM3 | minichromosome maintenance complex component 3 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MMP3 | matrix metallopeptidase 3 |
| MRAS | muscle RAS oncogene homolog |
| MT1B | metallothionein 1B |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1L | metallothionein 1L (gene/pseudogene) |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| MYH1 | myosin, heavy chain 1, skeletal muscle, adult |
| MZT1 | mitotic spindle organizing protein 1 |
| NDC1 | NDC1 transmembrane nucleoporin |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| NKX2-1 | NK2 homeobox 1 |
| NMB | neuromedin B |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) |
| NSG1 | neuron specific gene family member 1 |
| NUDC | nudC nuclear distribution protein |
| NUDCD1 | NudC domain containing 1 |
| NUF2 | NUF2, NDC80 kinetochore complex component |
| NUP88 | nucleoporin 88kDa |
| PA2G4 | proliferation-associated 2G4, 38kDa |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| PARP11 | poly (ADP-ribose) polymerase family, member 11 |
| PBK | PDZ binding kinase |
| PDCL3 | phosducin-like 3 |
| PDLIM5 | PDZ and LIM domain 5 |
| PGM2 | phosphoglucomutase 2 |
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PREB | prolactin regulatory element binding |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PRMT5 | protein arginine methyltransferase 5 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 |
| RAD18 | RAD18 E3 ubiquitin protein ligase |
| RPF2 | ribosome production factor 2 homolog (S. cerevisiae) |
| RRM2 | ribonucleotide reductase M2 |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SAMD11 | sterile alpha motif domain containing 11 |
| SERPINB7 | serpin peptidase inhibitor, clade B (ovalbumin), member 7 |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC25A11 | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 |
| SMS | spermine synthase |
| SNORD22 | small nucleolar RNA, C/D box 22 |
| SNRPA1 | small nuclear ribonucleoprotein polypeptide A' |
| SRM | spermidine synthase |
| SSTR1 | somatostatin receptor 1 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| STRA13 | stimulated by retinoic acid 13 |
| TAGLN3 | transgelin 3 |
| TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) |
| TCF19 | transcription factor 19 |
| TEX30 | testis expressed 30 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMEM130 | transmembrane protein 130 |
| TOMM34 | translocase of outer mitochondrial membrane 34 |
| TPM2 | tropomyosin 2 (beta) |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TRNP1 | TMF1-regulated nuclear protein 1 |
| TRPC3 | transient receptor potential cation channel, subfamily C, member 3 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 |
| TSPAN13 | tetraspanin 13 |
| TUBA3C | tubulin, alpha 3c |
| TUBA4A | tubulin, alpha 4a |
| TUBG1 | tubulin, gamma 1 |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UHRF1 | ubiquitin-like with PHD and ring finger domains 1 |
| UMPS | uridine monophosphate synthetase |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) |
| VEGFC | vascular endothelial growth factor C |
| WSB2 | WD repeat and SOCS box containing 2 |
| YEATS4 | YEATS domain containing 4 |
| YIPF3 | Yip1 domain family, member 3 |
| ZNF367 | zinc finger protein 367 |
| ZWILCH | zwilch kinetochore protein |
| ZWINT | ZW10 interacting kinetochore protein |
| Symbol | Name |
|---|---|
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 |
| ACCS | 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional) |
| ACVRL1 | activin A receptor type II-like 1 |
| ADAM17 | ADAM metallopeptidase domain 17 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ADORA2B | adenosine A2b receptor |
| ALPI | alkaline phosphatase, intestinal |
| ANGPTL2 | angiopoietin-like 2 |
| ANKRD29 | ankyrin repeat domain 29 |
| ANKRD33B | ankyrin repeat domain 33B |
| APOL3 | apolipoprotein L, 3 |
| ASS1 | argininosuccinate synthase 1 |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
| BCL10 | B-cell CLL/lymphoma 10 |
| BTBD19 | BTB (POZ) domain containing 19 |
| BTG2 | BTG family, member 2 |
| C10ORF54 | chromosome 10 open reading frame 54 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C1ORF52 | chromosome 1 open reading frame 52 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C6ORF1 | chromosome 6 open reading frame 1 |
| CALD1 | caldesmon 1 |
| CCL11 | chemokine (C-C motif) ligand 11 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 |
| CFH | complement factor H |
| CHL1 | cell adhesion molecule L1-like |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CLEC3B | C-type lectin domain family 3, member B |
| CMBL | carboxymethylenebutenolidase homolog (Pseudomonas) |
| COL8A2 | collagen, type VIII, alpha 2 |
| CTSF | cathepsin F |
| DAAM2 | dishevelled associated activator of morphogenesis 2 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like |
| DENND2A | DENN/MADD domain containing 2A |
| DHCR7 | 7-dehydrocholesterol reductase |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 |
| DPP4 | dipeptidyl-peptidase 4 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| DUSP4 | dual specificity phosphatase 4 |
| DYNC2LI1 | dynein, cytoplasmic 2, light intermediate chain 1 |
| DYRK1B | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B |
| EBP | emopamil binding protein (sterol isomerase) |
| ECH1 | enoyl CoA hydratase 1, peroxisomal |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| EPB41L4A-AS1 | EPB41L4A antisense RNA 1 |
| EPHB6 | EPH receptor B6 |
| EPSTI1 | epithelial stromal interaction 1 (breast) |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| EXOC6 | exocyst complex component 6 |
| F8 | coagulation factor VIII, procoagulant component |
| FADS1 | fatty acid desaturase 1 |
| FADS2 | fatty acid desaturase 2 |
| FAM131C | family with sequence similarity 131, member C |
| FAM213A | family with sequence similarity 213, member A |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
| FDPS | farnesyl diphosphate synthase |
| FDXR | ferredoxin reductase |
| FGGY | FGGY carbohydrate kinase domain containing |
| FIBIN | fin bud initiation factor homolog (zebrafish) |
| FTH1 | ferritin, heavy polypeptide 1 |
| GAS1 | growth arrest-specific 1 |
| GAS6 | growth arrest-specific 6 |
| GFRA1 | GDNF family receptor alpha 1 |
| GJD3 | gap junction protein, delta 3, 31.9kDa |
| GLI3 | GLI family zinc finger 3 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 |
| GSN | gelsolin |
| GYPC | glycophorin C (Gerbich blood group) |
| HHEX | hematopoietically expressed homeobox |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 |
| IGDCC4 | immunoglobulin superfamily, DCC subclass, member 4 |
| IL1B | interleukin 1, beta |
| INSIG1 | insulin induced gene 1 |
| IRS2 | insulin receptor substrate 2 |
| ITGB8 | integrin, beta 8 |
| KIAA0930 | KIAA0930 |
| KIAA1147 | KIAA1147 |
| KIAA1598 | |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLHL29 | kelch-like family member 29 |
| L1CAM | L1 cell adhesion molecule |
| LDLR | low density lipoprotein receptor |
| LOC100287704 | uncharacterized LOC100287704 |
| LOC653602 | uncharacterized LOC653602 |
| LONRF1 | LON peptidase N-terminal domain and ring finger 1 |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LPIN1 | lipin 1 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAMDC2 | MAM domain containing 2 |
| MAMLD1 | mastermind-like domain containing 1 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 |
| MME | membrane metallo-endopeptidase |
| MOB3C | MOB kinase activator 3C |
| MRGPRF | MAS-related GPR, member F |
| MSMO1 | methylsterol monooxygenase 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| MXD4 | MAX dimerization protein 4 |
| NBEA | neurobeachin |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NOV | nephroblastoma overexpressed |
| NTN4 | netrin 4 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OAF | OAF homolog (Drosophila) |
| OLFML2A | olfactomedin-like 2A |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 |
| PDE5A | phosphodiesterase 5A, cGMP-specific |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PGF | placental growth factor |
| PLBD2 | phospholipase B domain containing 2 |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHG4 | pleckstrin homology domain containing, family G (with RhoGef domain) member 4 |
| POR | P450 (cytochrome) oxidoreductase |
| PRKCI | protein kinase C, iota |
| PRKG1 | protein kinase, cGMP-dependent, type I |
| PRRT2 | proline-rich transmembrane protein 2 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| PYROXD2 | pyridine nucleotide-disulphide oxidoreductase domain 2 |
| QPRT | quinolinate phosphoribosyltransferase |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RCAN2 | regulator of calcineurin 2 |
| RNLS | renalase, FAD-dependent amine oxidase |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| SAMD5 | sterile alpha motif domain containing 5 |
| SC5D | sterol-C5-desaturase |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SDPR | serum deprivation response |
| SFTPB | surfactant protein B |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 |
| SLC22A18 | solute carrier family 22, member 18 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
| SNX18 | sorting nexin 18 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 |
| SUMF1 | sulfatase modifying factor 1 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TBC1D2B | TBC1 domain family, member 2B |
| TCEAL7 | transcription elongation factor A (SII)-like 7 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM119 | transmembrane protein 119 |
| TMEM258 | transmembrane protein 258 |
| TNXB | tenascin XB |
| TOX | thymocyte selection-associated high mobility group box |
| TP53INP1 | tumor protein p53 inducible nuclear protein 1 |
| TRERF1 | transcriptional regulating factor 1 |
| TRIM22 | tripartite motif containing 22 |
| TSC22D3 | TSC22 domain family, member 3 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSPAN9 | tetraspanin 9 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 |
| VAMP5 | vesicle-associated membrane protein 5 |
| XAF1 | XIAP associated factor 1 |
