CTCF Gene Set

Dataset JASPAR Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description CCCTC-binding factor (zinc finger protein)|This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] (NCBI Entrez Gene Database, 10664)
External Link http://www.ncbi.nlm.nih.gov/gene/10664
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Genes

35 target genes of the CTCF transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.

Symbol Name
ATP6V1G2-DDX39B ATP6V1G2-DDX39B readthrough (NMD candidate)
BRD2 bromodomain containing 2
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
EHMT2 euchromatic histone-lysine N-methyltransferase 2
FAM101B family with sequence similarity 101, member B
FAM21A family with sequence similarity 21, member A
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FLOT1 flotillin 1
GNL1 guanine nucleotide binding protein-like 1
GPHRB golgi pH regulator B
GTPBP6 GTP binding protein 6 (putative)
HCG26 HLA complex group 26 (non-protein coding)
HCP5 HLA complex P5 (non-protein coding)
HLA-E major histocompatibility complex, class I, E
LINC00685 long intergenic non-protein coding RNA 685
LOC401242 uncharacterized LOC401242
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MILR1 mast cell immunoglobulin-like receptor 1
MIR3648-1 microRNA 3648-1
MIR3687-1 microRNA 3687-1
NBPF14 neuroblastoma breakpoint family, member 14
NEU1 sialidase 1 (lysosomal sialidase)
PRRC2A proline-rich coiled-coil 2A
REXO1L1P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene
REXO1L2P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 2, pseudogene
RNF39 ring finger protein 39
SLC25A26 solute carrier family 25 (S-adenosylmethionine carrier), member 26
TCF19 transcription factor 19
TNF tumor necrosis factor
TNXB tenascin XB
TRIM26 tripartite motif containing 26
TRIM40 tripartite motif containing 40
VARS valyl-tRNA synthetase
ZFP57 ZFP57 zinc finger protein