| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | catenin (cadherin-associated protein), beta 1, 88kDa|The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009] (NCBI Entrez Gene Database, 1499) |
| External Link | https://ncbi.nlm.nih.gov/gene/1499 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the CTNNB1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0150845 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0103696 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0100482 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00958412 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00948515 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00941003 |
| ASS1 | argininosuccinate synthase 1 | 0.00938083 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00829403 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00819914 |
| COCH | cochlin | 0.00800188 |
| KRT19 | keratin 19, type I | 0.00799334 |
| CFB | complement factor B | 0.00798199 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.007831 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00779752 |
| ANXA1 | annexin A1 | 0.00765128 |
| TSPAN8 | tetraspanin 8 | 0.00744356 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00720506 |
| XIC | X chromosome inactivation center | 0.0072 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00715607 |
| HGD | homogentisate 1,2-dioxygenase | 0.00708426 |
| S100P | S100 calcium binding protein P | 0.00706317 |
| LCN2 | lipocalin 2 | 0.00694385 |
| MT1X | metallothionein 1X | 0.00688048 |
| HK2 | hexokinase 2 | 0.00680347 |
| KLHL24 | kelch-like family member 24 | 0.00673445 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00672334 |
| LTF | lactotransferrin | 0.00671044 |
| STXBP2 | syntaxin binding protein 2 | 0.00667569 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00659151 |
| GALC | galactosylceramidase | 0.00651409 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00642606 |
| CA12 | carbonic anhydrase XII | 0.006398 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00635455 |
| MT1F | metallothionein 1F | 0.0063494 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00624442 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.00619689 |
| TGFA | transforming growth factor, alpha | 0.00619413 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00613749 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.00605786 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.00605546 |
| VEGFA | vascular endothelial growth factor A | 0.00604587 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00598664 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.00598621 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00596441 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00595571 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00590556 |
| IRF7 | interferon regulatory factor 7 | 0.00584496 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00583572 |
| ZYX | zyxin | 0.00580774 |
| RGS2 | regulator of G-protein signaling 2 | 0.00576371 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | 0.0057397 |
| SPON2 | spondin 2, extracellular matrix protein | 0.00570973 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.00570467 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00568749 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00568687 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00567915 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00564945 |
| S100A11 | S100 calcium binding protein A11 | 0.00564345 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00563903 |
| MSMB | microseminoprotein, beta- | 0.0056304 |
| REG1A | regenerating islet-derived 1 alpha | 0.00560625 |
| TSPO | translocator protein (18kDa) | 0.00559128 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00558378 |
| MT1G | metallothionein 1G | 0.00557571 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00555814 |
| TSPAN1 | tetraspanin 1 | 0.00554133 |
| KRT15 | keratin 15, type I | 0.00549436 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00545675 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00544944 |
| GPR137B | G protein-coupled receptor 137B | 0.00544133 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00540451 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00534664 |
| MT1H | metallothionein 1H | 0.00534316 |
| KRT14 | keratin 14, type I | 0.00533559 |
| WDR45 | WD repeat domain 45 | 0.00530386 |
| FGB | fibrinogen beta chain | 0.00530018 |
| NID2 | nidogen 2 (osteonidogen) | 0.00524806 |
| KRT18 | keratin 18, type I | 0.00524226 |
| MT1M | metallothionein 1M | 0.00523966 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00521835 |
| SYT1 | synaptotagmin I | 0.0052066 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00518799 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.00518086 |
| PLK2 | polo-like kinase 2 | 0.00517135 |
| STC1 | stanniocalcin 1 | 0.00517096 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00515783 |
| FGG | fibrinogen gamma chain | 0.00512387 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00509798 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00508784 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00505402 |
| TMEM45A | transmembrane protein 45A | 0.0050231 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00499678 |
| CTSA | cathepsin A | 0.00499592 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | 0.00497572 |
| NELL2 | NEL-like 2 (chicken) | 0.00496246 |
| PDGFC | platelet derived growth factor C | 0.00494962 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00492886 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00489487 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.00488797 |
| SORBS3 | sorbin and SH3 domain containing 3 | 0.00487618 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00486925 |
| MFSD1 | major facilitator superfamily domain containing 1 | 0.0048679 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00486254 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.00486163 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00485181 |
| KRT13 | keratin 13, type I | 0.00484899 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00483319 |
| ASPA | aspartoacylase | 0.0047982 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00478521 |
| RELN | reelin | 0.00476995 |
| GPM6B | glycoprotein M6B | 0.00474875 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00474477 |
| FEM1C | fem-1 homolog c (C. elegans) | 0.00471869 |
| MGLL | monoglyceride lipase | 0.00470955 |
| NMRK1 | nicotinamide riboside kinase 1 | 0.00470835 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | 0.00470317 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00469005 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 0.0046789 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.00466441 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00466175 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00466058 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00463081 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00462501 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00462161 |
| FAM13A | family with sequence similarity 13, member A | 0.00461844 |
| CALB1 | calbindin 1, 28kDa | 0.00461641 |
| CCNG2 | cyclin G2 | 0.0046066 |
| COG7 | component of oligomeric golgi complex 7 | 0.00459757 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 0.00458967 |
| NDRG1 | N-myc downstream regulated 1 | 0.0045697 |
| TGM2 | transglutaminase 2 | 0.00456667 |
| IRS2 | insulin receptor substrate 2 | 0.00456485 |
| PLPP2 | phospholipid phosphatase 2 | 0.00455662 |
| IPO13 | importin 13 | 0.00455351 |
| MID1IP1 | MID1 interacting protein 1 | 0.00454244 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00453882 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.00452497 |
| KRT17 | keratin 17, type I | 0.00452088 |
| CSTA | cystatin A (stefin A) | 0.00452067 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 | 0.00452036 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00451503 |
| MVP | major vault protein | 0.00451103 |
| IGF1R | insulin-like growth factor 1 receptor | 0.00450949 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.00448431 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00446563 |
| EFNA1 | ephrin-A1 | 0.00446166 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00445471 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00443068 |
| IL32 | interleukin 32 | 0.00441791 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00440309 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00440059 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0043988 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | 0.00439849 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00439187 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | 0.00439124 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.00439079 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.00438472 |
| APOC1 | apolipoprotein C-I | 0.00436627 |
| ATF3 | activating transcription factor 3 | 0.00436537 |
| SLC25A46 | solute carrier family 25, member 46 | 0.00435057 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00434698 |
| MAGEA1 | melanoma antigen family A1 | 0.00431686 |
| TFRC | transferrin receptor | 0.0043156 |
| PBLD | phenazine biosynthesis-like protein domain containing | 0.0043057 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00426271 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00426231 |
| FGF13 | fibroblast growth factor 13 | 0.00425101 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.004247 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.0042426 |
| ECM1 | extracellular matrix protein 1 | 0.00424101 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00422724 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00421948 |
| PTEN | phosphatase and tensin homolog | 0.00421792 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | 0.00421537 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00421167 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.00420746 |
| CD37 | CD37 molecule | 0.00419009 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00418998 |
| KRT8 | keratin 8, type II | 0.00417809 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00415702 |
| TMEM176B | transmembrane protein 176B | 0.0041516 |
| AOC1 | amine oxidase, copper containing 1 | 0.00414719 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0041466 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00414288 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | 0.00413597 |
| PRAME | preferentially expressed antigen in melanoma | 0.00413134 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.00412711 |
| SQSTM1 | sequestosome 1 | 0.00411107 |
| BEX4 | brain expressed, X-linked 4 | 0.00410867 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.004104 |
| LXN | latexin | 0.00410321 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00409426 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.00407841 |
| PRSS21 | protease, serine, 21 (testisin) | 0.00406741 |
| ADIRF | adipogenesis regulatory factor | 0.00406655 |
| SLC22A18 | solute carrier family 22, member 18 | 0.0040635 |
| HLA-B | major histocompatibility complex, class I, B | 0.00405436 |
| MINK1 | misshapen-like kinase 1 | 0.00404268 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | 0.00403863 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.00403766 |
| COMT | catechol-O-methyltransferase | 0.00402731 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00402531 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00401087 |
| MT2A | metallothionein 2A | 0.00400832 |
| TUBB6 | tubulin, beta 6 class V | 0.00399745 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00399698 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00399482 |
| JUNB | jun B proto-oncogene | 0.00398923 |
| JMJD6 | jumonji domain containing 6 | 0.0039848 |
| PELO | pelota homolog (Drosophila) | 0.00397905 |
| MTF2 | metal response element binding transcription factor 2 | 0.00397193 |
| RRAGD | Ras-related GTP binding D | 0.00397097 |
| R3HDM4 | R3H domain containing 4 | 0.00397056 |
| CTSC | cathepsin C | 0.00396617 |
| CPM | carboxypeptidase M | 0.00396159 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00394172 |
| RIN2 | Ras and Rab interactor 2 | 0.00391919 |
| HMGA1 | high mobility group AT-hook 1 | 0.00391868 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00390617 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00389961 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.00389013 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.00387479 |
| OGFRL1 | opioid growth factor receptor-like 1 | 0.00386841 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00386509 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | 0.00385276 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0038491 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00384905 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00384328 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00383088 |
| DDT | D-dopachrome tautomerase | 0.0038257 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.00382308 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00382112 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | 0.00381965 |
| GOLT1B | golgi transport 1B | 0.00380896 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00380458 |
| CRYAB | crystallin, alpha B | 0.00378813 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00378648 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | 0.00378625 |
| ANK2 | ankyrin 2, neuronal | 0.00378131 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.00377865 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 0.00377399 |
| S100A7 | S100 calcium binding protein A7 | 0.00377269 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00377177 |
| EGR1 | early growth response 1 | 0.00375176 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00372657 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.00371008 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 0.00370447 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00370171 |
| ALDOB | aldolase B, fructose-bisphosphate | 0.00369388 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.00368459 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | -0.0101949 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00816183 |
| CDCA4 | cell division cycle associated 4 | -0.0080739 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00768677 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00753313 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00727653 |
| CCNF | cyclin F | -0.00684788 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.00679604 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.006654 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.006453 |
| CD1E | CD1e molecule | -0.00644274 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.00633392 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0062184 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00612486 |
| GLO1 | glyoxalase I | -0.00612346 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | -0.00606023 |
| PRKD3 | protein kinase D3 | -0.00605919 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00597885 |
| ACTB | actin, beta | -0.00589064 |
| EXPH5 | exophilin 5 | -0.00586711 |
| XPO7 | exportin 7 | -0.00569976 |
| IFT57 | intraflagellar transport 57 | -0.0056237 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00558686 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.00552241 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 | -0.00551393 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | -0.00551033 |
| CALD1 | caldesmon 1 | -0.00548025 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.00547154 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.00546286 |
| HOPX | HOP homeobox | -0.00534172 |
| FABP7 | fatty acid binding protein 7, brain | -0.00530665 |
| AURKB | aurora kinase B | -0.00528549 |
| EREG | epiregulin | -0.00526627 |
| COMP | cartilage oligomeric matrix protein | -0.00522862 |
| CLIC3 | chloride intracellular channel 3 | -0.00519615 |
| CHEK1 | checkpoint kinase 1 | -0.00508395 |
| MFAP5 | microfibrillar associated protein 5 | -0.00505311 |
| CADM1 | cell adhesion molecule 1 | -0.00502604 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00502225 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00497125 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00493496 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.00489965 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.00487856 |
| PLPBP | pyridoxal phosphate binding protein | -0.00483855 |
| CPE | carboxypeptidase E | -0.00479623 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | -0.0047897 |
| NPR3 | natriuretic peptide receptor 3 | -0.00478291 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00475983 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | -0.00475466 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.00473522 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00472695 |
| KIF15 | kinesin family member 15 | -0.00471468 |
| SCG5 | secretogranin V | -0.00471405 |
| DDHD2 | DDHD domain containing 2 | -0.00470751 |
| TSPAN7 | tetraspanin 7 | -0.00469611 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.00468923 |
| PRMT1 | protein arginine methyltransferase 1 | -0.00465237 |
| CDC20 | cell division cycle 20 | -0.00461034 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00458047 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.00457424 |
| KLK5 | kallikrein-related peptidase 5 | -0.00456706 |
| PPA1 | pyrophosphatase (inorganic) 1 | -0.00456267 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.00455488 |
| HOXA5 | homeobox A5 | -0.00450535 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00450396 |
| FBN1 | fibrillin 1 | -0.00449857 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.00447886 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00447491 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00445666 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00445508 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.00442262 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | -0.00440388 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00440304 |
| CCNA2 | cyclin A2 | -0.00438304 |
| ANXA6 | annexin A6 | -0.00437987 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00436368 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00435858 |
| UNG | uracil-DNA glycosylase | -0.00433739 |
| CSK | c-src tyrosine kinase | -0.00432091 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.00432011 |
| CD1B | CD1b molecule | -0.00430545 |
| CD99 | CD99 molecule | -0.00428431 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | -0.00427556 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00425066 |
| FHL1 | four and a half LIM domains 1 | -0.00421055 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.0042055 |
| DLAT | dihydrolipoamide S-acetyltransferase | -0.00420486 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00419571 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00419156 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00418119 |
| IL18 | interleukin 18 | -0.00418083 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.00417726 |
| ANGPT1 | angiopoietin 1 | -0.00417199 |
| MMP2 | matrix metallopeptidase 2 | -0.00415006 |
| DCPS | decapping enzyme, scavenger | -0.00413391 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -0.00412877 |
| CCNB2 | cyclin B2 | -0.00412234 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00412153 |
| KDM1A | lysine (K)-specific demethylase 1A | -0.00411716 |
| H2AX | H2A.X variant histone | -0.00410365 |
| IFRD2 | interferon-related developmental regulator 2 | -0.00410123 |
| ZW10 | zw10 kinetochore protein | -0.0040964 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00407468 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | -0.00407405 |
| METRN | meteorin, glial cell differentiation regulator | -0.00407379 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.00406733 |
| HYOU1 | hypoxia up-regulated 1 | -0.00406511 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00404431 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | -0.00403399 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00403054 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | -0.0040189 |
| RPA3 | replication protein A3, 14kDa | -0.00401747 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | -0.00401351 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 | -0.0040105 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | -0.00400575 |
| PRDX4 | peroxiredoxin 4 | -0.00399656 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.0039896 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.00398439 |
| ANOS1 | anosmin 1 | -0.0039842 |
| PCLAF | PCNA clamp associated factor | -0.00397728 |
| CD93 | CD93 molecule | -0.00397711 |
| CENPF | centromere protein F, 350/400kDa | -0.00397576 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.00396997 |
| KIF11 | kinesin family member 11 | -0.00396719 |
| GPSM2 | G-protein signaling modulator 2 | -0.00396347 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | -0.00395908 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | -0.00395513 |
| STARD7 | StAR-related lipid transfer (START) domain containing 7 | -0.00393652 |
| IPO5 | importin 5 | -0.00390627 |
| THAP12 | THAP domain containing 12 | -0.00390389 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0038917 |
| MSH2 | mutS homolog 2 | -0.00389053 |
| ZNF395 | zinc finger protein 395 | -0.00388438 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00385433 |
| ELAVL1 | ELAV like RNA binding protein 1 | -0.00384833 |
| CCDC92 | coiled-coil domain containing 92 | -0.00383525 |
| AUTS2 | autism susceptibility candidate 2 | -0.00383163 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 | -0.00382739 |
| HMGB1 | high mobility group box 1 | -0.00382726 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00382526 |
| MIS18A | MIS18 kinetochore protein A | -0.00380864 |
| PTK7 | protein tyrosine kinase 7 (inactive) | -0.00379853 |
| ACOT9 | acyl-CoA thioesterase 9 | -0.00379717 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.00379686 |
| FOCAD | focadhesin | -0.00379328 |
| TLR4 | toll-like receptor 4 | -0.00378067 |
| PROM1 | prominin 1 | -0.00376582 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.00375653 |
| FAM169A | family with sequence similarity 169, member A | -0.00375357 |
| SPON1 | spondin 1, extracellular matrix protein | -0.0037516 |
| KIF14 | kinesin family member 14 | -0.00375106 |
| TMEM38B | transmembrane protein 38B | -0.00374424 |
| RDX | radixin | -0.00371888 |
| HMGB3 | high mobility group box 3 | -0.00370398 |
| METTL8 | methyltransferase like 8 | -0.00369935 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00368801 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00367734 |
| MDFIC | MyoD family inhibitor domain containing | -0.00366533 |
| PER3 | period circadian clock 3 | -0.00365057 |
| TPX2 | TPX2, microtubule-associated | -0.00364612 |
| EPHB2 | EPH receptor B2 | -0.00364506 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.00363871 |
| FTO | fat mass and obesity associated | -0.00362716 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00362458 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.0036189 |
| CALCRL | calcitonin receptor-like | -0.00360184 |
| CCND1 | cyclin D1 | -0.00358398 |
| NDNF | neuron-derived neurotrophic factor | -0.00358116 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00357848 |
| PRKCH | protein kinase C, eta | -0.00356136 |
| ANXA3 | annexin A3 | -0.00354672 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00354285 |
| PRRX1 | paired related homeobox 1 | -0.00353447 |
| SUMO3 | small ubiquitin-like modifier 3 | -0.00352898 |
| CFAP298 | cilia and flagella associated protein 298 | -0.00352875 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | -0.00352215 |
| THYN1 | thymocyte nuclear protein 1 | -0.00351753 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | -0.00351748 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00351444 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog | -0.00350799 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | -0.00350325 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.00350032 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | -0.00349996 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.00347453 |
| TYMS | thymidylate synthetase | -0.00346479 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | -0.00345988 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | -0.00345486 |
| SIVA1 | SIVA1, apoptosis-inducing factor | -0.0034542 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | -0.00345377 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | -0.0034459 |
| WWC3 | WWC family member 3 | -0.00344065 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | -0.00343766 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | -0.003437 |
| PROCR | protein C receptor, endothelial | -0.00343555 |
| ELANE | elastase, neutrophil expressed | -0.00342374 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00341597 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | -0.00341407 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.00341339 |
| IVNS1ABP | influenza virus NS1A binding protein | -0.00341295 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00340865 |
| MPZL2 | myelin protein zero-like 2 | -0.00340795 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -0.00340185 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00339707 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00339633 |
| TFDP1 | transcription factor Dp-1 | -0.00339409 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.00339302 |
| MCM6 | minichromosome maintenance complex component 6 | -0.00339295 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -0.00339276 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.00338437 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00338365 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | -0.00338047 |
| TNC | tenascin C | -0.00337343 |
| PON3 | paraoxonase 3 | -0.00336606 |
| CTSZ | cathepsin Z | -0.00336312 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00336302 |
| CEP57 | centrosomal protein 57kDa | -0.00336195 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -0.00335933 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | -0.00335522 |
| TK1 | thymidine kinase 1, soluble | -0.00335045 |
| RBBP4 | retinoblastoma binding protein 4 | -0.00334293 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | -0.00334142 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00334023 |
| CCND2 | cyclin D2 | -0.00333196 |
| ATP6V1B2 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | -0.00332437 |
| DHCR7 | 7-dehydrocholesterol reductase | -0.00332375 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.00332374 |
| H1-0 | H1.0 linker histone | -0.00331826 |
| ILF2 | interleukin enhancer binding factor 2 | -0.00331789 |
| E2F8 | E2F transcription factor 8 | -0.00331777 |
| ASF1B | anti-silencing function 1B histone chaperone | -0.0033111 |
| EPYC | epiphycan | -0.00330891 |
| THOC7 | THO complex 7 | -0.00330613 |
| PRPF8 | pre-mRNA processing factor 8 | -0.00330399 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | -0.0033028 |
| ELN | elastin | -0.00329687 |
| SETMAR | SET domain and mariner transposase fusion gene | -0.00329197 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00328647 |
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial | -0.00328365 |
| RSU1 | Ras suppressor protein 1 | -0.00328319 |
| RPA1 | replication protein A1, 70kDa | -0.0032809 |
| ADA | adenosine deaminase | -0.00327213 |
| RAPSN | receptor-associated protein of the synapse | -0.00327129 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | -0.003249 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.00324528 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.00324186 |
| COL10A1 | collagen, type X, alpha 1 | -0.00323787 |
| CCDC25 | coiled-coil domain containing 25 | -0.00323535 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | -0.00323463 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.00323126 |
| APH1A | APH1A gamma secretase subunit | -0.00323025 |
