CTSG Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description cathepsin G|The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 1511)
External Link http://www.ncbi.nlm.nih.gov/gene/1511
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258 interacting proteins for CTSG from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
A2M alpha-2-macroglobulin
AARD alanine and arginine rich domain containing protein
ACTB actin, beta
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALPP alkaline phosphatase, placental
ALYREF Aly/REF export factor
ANXA1 annexin A1
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOD apolipoprotein D
ARL8B ADP-ribosylation factor-like 8B
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
AZU1 azurocidin 1
BANF1 barrier to autointegration factor 1
C3 complement component 3
CAMP cathelicidin antimicrobial peptide
CAPN6 calpain 6
CASP7 caspase 7, apoptosis-related cysteine peptidase
CBX3 chromobox homolog 3
CGGBP1 CGG triplet repeat binding protein 1
CIRBP cold inducible RNA binding protein
CKB creatine kinase, brain
CKMT1A creatine kinase, mitochondrial 1A
CMSS1 cms1 ribosomal small subunit homolog (yeast)
CNBP CCHC-type zinc finger, nucleic acid binding protein
CRCP CGRP receptor component
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEFA1 defensin, alpha 1
DEFA3 defensin, alpha 3, neutrophil-specific
DEFA4 defensin, alpha 4, corticostatin
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DMBT1 deleted in malignant brain tumors 1
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
ELANE elastase, neutrophil expressed
ELF1 E74-like factor 1 (ets domain transcription factor)
ERBB2IP erbb2 interacting protein
ERI1 exoribonuclease 1
EWSR1 EWS RNA-binding protein 1
EXOSC1 exosome component 1
EXOSC10 exosome component 10
EXOSC2 exosome component 2
EXOSC4 exosome component 4
EXOSC5 exosome component 5
EXOSC6 exosome component 6
EXOSC8 exosome component 8
EXOSC9 exosome component 9
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F2RL2 coagulation factor II (thrombin) receptor-like 2
F5 coagulation factor V (proaccelerin, labile factor)
FOXK1 forkhead box K1
FTSJ3 FtsJ homolog 3 (E. coli)
FUS FUS RNA binding protein
FYTTD1 forty-two-three domain containing 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GBA glucosidase, beta, acid
GFAP glial fibrillary acidic protein
GLB1 galactosidase, beta 1
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPATCH4 G patch domain containing 4
GTF2I general transcription factor IIi
GUSB glucuronidase, beta
H1FX H1 histone family, member X
H2AFJ H2A histone family, member J
HIST1H1B histone cluster 1, H1b
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HIST1H2AB histone cluster 1, H2ab
HIST1H2AC histone cluster 1, H2ac
HIST1H2AD histone cluster 1, H2ad
HIST1H2AH histone cluster 1, H2ah
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BA histone cluster 1, H2ba
HIST1H2BD histone cluster 1, H2bd
HIST1H2BF histone cluster 1, H2bf
HIST1H2BH histone cluster 1, H2bh
HIST1H2BK histone cluster 1, H2bk
HIST1H2BL histone cluster 1, H2bl
HIST1H2BM histone cluster 1, H2bm
HIST1H2BN histone cluster 1, H2bn
HIST1H4F histone cluster 1, H4f
HIST2H2AA4 histone cluster 2, H2aa4
HIST2H2AC histone cluster 2, H2ac
HIST2H2BF histone cluster 2, H2bf
HIST3H2A histone cluster 3, H2a
HMGA1 high mobility group AT-hook 1
HMGB1 high mobility group box 1
HMGB2 high mobility group box 2
HMGB3 high mobility group box 3
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPR heterogeneous nuclear ribonucleoprotein R
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HP1BP3 heterochromatin protein 1, binding protein 3
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFALS insulin-like growth factor binding protein, acid labile subunit
IGFBP3 insulin-like growth factor binding protein 3
IGHA1 immunoglobulin heavy constant alpha 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker)
IGKC immunoglobulin kappa constant
IGLC1 immunoglobulin lambda constant 1 (Mcg marker)
IGLC2 immunoglobulin lambda constant 2 (Kern-Oz- marker)
IGLC6 immunoglobulin lambda constant 6 (Kern+Oz- marker, gene/pseudogene)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KNG1 kininogen 1
KPNA3 karyopherin alpha 3 (importin alpha 4)
KPNA4 karyopherin alpha 4 (importin alpha 3)
KPNB1 karyopherin (importin) beta 1
LIG3 ligase III, DNA, ATP-dependent
LRP1 low density lipoprotein receptor-related protein 1
LTF lactotransferrin
LYZ lysozyme
MAOA monoamine oxidase A
MGME1 mitochondrial genome maintenance exonuclease 1
MMP1 matrix metallopeptidase 1
MMP9 matrix metallopeptidase 9
MNDA myeloid cell nuclear differentiation antigen
MPG N-methylpurine-DNA glycosylase
MPO myeloperoxidase
MSH2 mutS homolog 2
MSH3 mutS homolog 3
NCL nucleolin
PARP1 poly (ADP-ribose) polymerase 1
PFN1 profilin 1
PIP prolactin-induced protein
PLAUR plasminogen activator, urokinase receptor
PNKP polynucleotide kinase 3'-phosphatase
POLG polymerase (DNA directed), gamma
POLR1C polymerase (RNA) I polypeptide C, 30kDa
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
POLRMT polymerase (RNA) mitochondrial (DNA directed)
POU2F1 POU class 2 homeobox 1
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRTN3 proteinase 3
PSIP1 PC4 and SFRS1 interacting protein 1
RAD21 RAD21 homolog (S. pombe)
RALY RALY heterogeneous nuclear ribonucleoprotein
RBM14 RNA binding motif protein 14
RBM28 RNA binding motif protein 28
RBM3 RNA binding motif (RNP1, RRM) protein 3
RBMS1 RNA binding motif, single stranded interacting protein 1
RBMX RNA binding motif protein, X-linked
RECQL RecQ helicase-like
REPIN1 replication initiator 1
RFC1 replication factor C (activator 1) 1, 145kDa
RFC2 replication factor C (activator 1) 2, 40kDa
RFC3 replication factor C (activator 1) 3, 38kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RNASE3 ribonuclease, RNase A family, 3
RPA1 replication protein A1, 70kDa
RPA2 replication protein A2, 32kDa
RPA3 replication protein A3, 14kDa
RPL22 ribosomal protein L22
RPL24 ribosomal protein L24
RPL31 ribosomal protein L31
RPL4 ribosomal protein L4
RPS10 ribosomal protein S10
RPS11 ribosomal protein S11
RPS15A ribosomal protein S15a
RPS23 ribosomal protein S23
RPS24 ribosomal protein S24
RPS25 ribosomal protein S25
RPS26 ribosomal protein S26
RPS3 ribosomal protein S3
RPS4X ribosomal protein S4, X-linked
RPS6 ribosomal protein S6
RPS7 ribosomal protein S7
RPS8 ribosomal protein S8
RPUSD3 RNA pseudouridylate synthase domain containing 3
RSL1D1 ribosomal L1 domain containing 1
SATB1 SATB homeobox 1
SCARB2 scavenger receptor class B, member 2
SDC1 syndecan 1
SELPLG selectin P ligand
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SET SET nuclear proto-oncogene
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SNRPA1 small nuclear ribonucleoprotein polypeptide A'
SNRPB2 small nuclear ribonucleoprotein polypeptide B
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa
SPI1 Spi-1 proto-oncogene
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
SRP9 signal recognition particle 9kDa
SRSF2 serine/arginine-rich splicing factor 2
SRSF3 serine/arginine-rich splicing factor 3
SRSF5 serine/arginine-rich splicing factor 5
SSB Sjogren syndrome antigen B (autoantigen La)
SSBP1 single-stranded DNA binding protein 1, mitochondrial
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STS steroid sulfatase (microsomal), isozyme S
SUB1 SUB1 homolog (S. cerevisiae)
TCEANC2 transcription elongation factor A (SII) N-terminal and central domain containing 2
TFAM transcription factor A, mitochondrial
THBS1 thrombospondin 1
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
TOP1 topoisomerase (DNA) I
TPP1 tripeptidyl peptidase I
U2AF2 U2 small nuclear RNA auxiliary factor 2
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UHRF1 ubiquitin-like with PHD and ring finger domains 1
USP10 ubiquitin specific peptidase 10
VCAM1 vascular cell adhesion molecule 1
VDAC1 voltage-dependent anion channel 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YBX1 Y box binding protein 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta