CTSK Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description cathepsin K|The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. [provided by RefSeq, Apr 2013] (NCBI Entrez Gene Database, 1513)
External Link http://www.ncbi.nlm.nih.gov/gene/1513
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23 interacting proteins for CTSK from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
COL18A1 collagen, type XVIII, alpha 1
FGFR3 fibroblast growth factor receptor 3
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
KNG1 kininogen 1
LIG4 ligase IV, DNA, ATP-dependent
MMP13 matrix metallopeptidase 13
MMP7 matrix metallopeptidase 7
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9