CUL2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description cullin 2| (NCBI Entrez Gene Database, 8453)
External Link https://ncbi.nlm.nih.gov/gene/8453
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Genes

498 genes differentially expressed following the CUL2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
FGFR3 fibroblast growth factor receptor 3 0.0162602
RPA3 replication protein A3, 14kDa 0.0158779
BEX1 brain expressed, X-linked 1 0.0154227
SEPP1 selenoprotein P, plasma, 1 0.0139402
LTF lactotransferrin 0.0137169
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.0126104
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.0123788
CDCA4 cell division cycle associated 4 0.0121701
SSBP2 single-stranded DNA binding protein 2 0.0119712
MAP7 microtubule-associated protein 7 0.0119545
CLU clusterin 0.0118868
VCAM1 vascular cell adhesion molecule 1 0.0118286
CXCL14 chemokine (C-X-C motif) ligand 14 0.01136
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.0108027
PITX3 paired-like homeodomain 3 0.0106838
ADD3 adducin 3 (gamma) 0.0104108
RPS5 ribosomal protein S5 0.0103969
CPVL carboxypeptidase, vitellogenic-like 0.0102301
TMEM38B transmembrane protein 38B 0.0101887
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.0101858
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.00998971
S100A9 S100 calcium binding protein A9 0.00998532
DCXR dicarbonyl/L-xylulose reductase 0.00998338
NUSAP1 nucleolar and spindle associated protein 1 0.00994498
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00992366
CDKN3 cyclin-dependent kinase inhibitor 3 0.00990535
MMP9 matrix metallopeptidase 9 0.00977333
HILPDA hypoxia inducible lipid droplet-associated 0.0097592
ACAT2 acetyl-CoA acetyltransferase 2 0.00971357
PTTG1 pituitary tumor-transforming 1 0.0095446
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.00950809
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00950809
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00949639
DLK1 delta-like 1 homolog (Drosophila) 0.00948768
DCK deoxycytidine kinase 0.00944997
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00943367
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 0.00941843
AMD1 adenosylmethionine decarboxylase 1 0.0094137
DHCR7 7-dehydrocholesterol reductase 0.00940371
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.00934423
GSTA4 glutathione S-transferase alpha 4 0.00933261
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00933238
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.0093283
COPS4 COP9 signalosome subunit 4 0.00924206
COX7B cytochrome c oxidase subunit VIIb 0.00922449
DNASE1L3 deoxyribonuclease I-like 3 0.00908683
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.00904294
SKP1 S-phase kinase-associated protein 1 0.00899126
CLC Charcot-Leyden crystal galectin 0.00897776
DEFA4 defensin, alpha 4, corticostatin 0.00897678
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00890672
MSMO1 methylsterol monooxygenase 1 0.0088917
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.00887452
COMMD10 COMM domain containing 10 0.00886824
MOCS2 molybdenum cofactor synthesis 2 0.0088133
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00881283
LYZ lysozyme 0.00879075
CYB5A cytochrome b5 type A (microsomal) 0.00876236
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.00874889
TXNDC9 thioredoxin domain containing 9 0.00870616
COMMD8 COMM domain containing 8 0.00870134
LRRC17 leucine rich repeat containing 17 0.00869332
CLCA1 chloride channel accessory 1 0.00862851
BPI bactericidal/permeability-increasing protein 0.0086219
GJA1 gap junction protein, alpha 1, 43kDa 0.00857164
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00857156
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00849876
OIP5 Opa interacting protein 5 0.00849862
CST7 cystatin F (leukocystatin) 0.00849178
ARG1 arginase 1 0.00845551
CCNA2 cyclin A2 0.0084498
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 0.0084372
TEX30 testis expressed 30 0.00842472
TSPAN6 tetraspanin 6 0.00838632
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00837613
BIRC5 baculoviral IAP repeat containing 5 0.0083739
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.00837368
PRKD3 protein kinase D3 0.00835774
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00833104
ATF1 activating transcription factor 1 0.00832972
CTSG cathepsin G 0.00828438
SUMO3 small ubiquitin-like modifier 3 0.00826697
HOPX HOP homeobox 0.00820028
WDR61 WD repeat domain 61 0.0081835
ADK adenosine kinase 0.00817783
METTL7A methyltransferase like 7A 0.00813428
ANGPT1 angiopoietin 1 0.00797545
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.00797148
FBXO5 F-box protein 5 0.00796455
FABP1 fatty acid binding protein 1, liver 0.0079594
CCNF cyclin F 0.00795835
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00791468
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.00786087
CDC42 cell division cycle 42 0.00785726
TMEM14B transmembrane protein 14B 0.00782399
CETN2 centrin, EF-hand protein, 2 0.00776725
POLB polymerase (DNA directed), beta 0.00775824
LYPLA1 lysophospholipase I 0.00774699
CKS2 CDC28 protein kinase regulatory subunit 2 0.00769866
MGAM maltase-glucoamylase 0.0076805
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00767868
HTRA1 HtrA serine peptidase 1 0.00766846
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00766487
SPC25 SPC25, NDC80 kinetochore complex component 0.00761309
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00760787
KIF20A kinesin family member 20A 0.00760388
TMEM126B transmembrane protein 126B 0.00756612
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.00754575
CDK1 cyclin-dependent kinase 1 0.00753576
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00750883
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00749625
FAM162A family with sequence similarity 162, member A 0.00745561
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.00745545
TARP TCR gamma alternate reading frame protein 0.00745214
NXT2 nuclear transport factor 2-like export factor 2 0.00744661
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 0.00742943
SOCS5 suppressor of cytokine signaling 5 0.00742651
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 0.00742525
CXCL12 chemokine (C-X-C motif) ligand 12 0.00741781
FASN fatty acid synthase 0.00738655
DMAC2L distal membrane arm assembly component 2 like 0.00736456
SNRPG small nuclear ribonucleoprotein polypeptide G 0.00731369
AUTS2 autism susceptibility candidate 2 0.00727161
PPA2 pyrophosphatase (inorganic) 2 0.007243
CRIP2 cysteine-rich protein 2 0.00723603
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00718877
C3ORF14 chromosome 3 open reading frame 14 0.00717286
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 0.00716068
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 0.00715549
TMSB15A thymosin beta 15a 0.00713919
PCOLCE2 procollagen C-endopeptidase enhancer 2 0.00713899
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 0.00713162
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00712883
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 0.00712569
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 0.00711602
CSTA cystatin A (stefin A) 0.00710745
RPL26L1 ribosomal protein L26-like 1 0.00710508
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00709785
ATP5PD ATP synthase peripheral stalk subunit d 0.00708439
HSDL2 hydroxysteroid dehydrogenase like 2 0.00708082
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.0070786
AURKA aurora kinase A 0.00703712
COL1A2 collagen, type I, alpha 2 0.00703403
GEMIN2 gem (nuclear organelle) associated protein 2 0.00703007
LAPTM4B lysosomal protein transmembrane 4 beta 0.00701684
MXRA7 matrix-remodelling associated 7 0.00701101
THOC7 THO complex 7 0.00699719
UBE2C ubiquitin-conjugating enzyme E2C 0.00699399
HIGD1A HIG1 hypoxia inducible domain family, member 1A 0.00698603
OLFM4 olfactomedin 4 0.00697731
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.00697165
DBF4 DBF4 zinc finger 0.00697085
PRDX2 peroxiredoxin 2 0.00693621
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00692178
EFHC2 EF-hand domain (C-terminal) containing 2 0.00692147
IFT52 intraflagellar transport 52 0.00691372
COL3A1 collagen, type III, alpha 1 0.00688274
RACGAP1 Rac GTPase activating protein 1 0.00686314
CGRRF1 cell growth regulator with ring finger domain 1 0.00686232
GNG10 guanine nucleotide binding protein (G protein), gamma 10 0.00685957
VBP1 von Hippel-Lindau binding protein 1 0.00685887
NT5C3A 5'-nucleotidase, cytosolic IIIA 0.0068567
PENK proenkephalin 0.00685431
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.00684856
SIVA1 SIVA1, apoptosis-inducing factor 0.0068244
ALG8 ALG8, alpha-1,3-glucosyltransferase 0.00681878
ADI1 acireductone dioxygenase 1 0.00681652
NSL1 NSL1, MIS12 kinetochore complex component 0.00678168
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00675381
SELENBP1 selenium binding protein 1 0.00674961
ESD esterase D 0.00673235
CD59 CD59 molecule, complement regulatory protein 0.00671719
NPY neuropeptide Y 0.00671149
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 0.00670523
CNN3 calponin 3, acidic 0.0066954
IDI1 isopentenyl-diphosphate delta isomerase 1 0.00668846
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00667395
FBXO11 F-box protein 11 0.00666512
HAT1 histone acetyltransferase 1 0.00666401
CHKB choline kinase beta 0.00664248
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00664189
GUCY1B3 guanylate cyclase 1, soluble, beta 3 0.00663973
ZDHHC4 zinc finger, DHHC-type containing 4 0.00663645
RIDA reactive intermediate imine deaminase A homolog 0.0066242
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00661766
SDC2 syndecan 2 0.00661606
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00660278
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.00660205
MED21 mediator complex subunit 21 0.00658622
PRELID3B PRELI domain containing 3B 0.00658558
GTF2A2 general transcription factor IIA, 2, 12kDa 0.00657802
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.00656611
VDAC3 voltage-dependent anion channel 3 0.00656326
APOO apolipoprotein O 0.00655636
HIKESHI heat shock protein nuclear import factor hikeshi 0.00655549
HP haptoglobin 0.00655085
GTF2H5 general transcription factor IIH, polypeptide 5 0.00654594
EAPP E2F-associated phosphoprotein 0.00652372
DOK5 docking protein 5 0.00652077
OLFM1 olfactomedin 1 0.00651537
KRT10 keratin 10, type I 0.00650651
HDAC2 histone deacetylase 2 0.00649734
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 0.00648819
SPRY2 sprouty homolog 2 (Drosophila) 0.00647823
B3GNT1 0.00647594
NELL1 NEL-like 1 (chicken) 0.00647548
MRPL48 mitochondrial ribosomal protein L48 0.00647221
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00646066
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00645003
RPA2 replication protein A2, 32kDa 0.00644917
GSTO1 glutathione S-transferase omega 1 0.00644027
EIF4E eukaryotic translation initiation factor 4E 0.00644011
MED28 mediator complex subunit 28 0.00642809
C1D C1D nuclear receptor corepressor 0.00642682
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00642391
GCA grancalcin, EF-hand calcium binding protein 0.00640644
CKS1B CDC28 protein kinase regulatory subunit 1B 0.00640184
CCNC cyclin C 0.00639157
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.0063897
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 0.00638293
HINT1 histidine triad nucleotide binding protein 1 0.00637502
ANAPC10 anaphase promoting complex subunit 10 0.00637427
ANAPC15 anaphase promoting complex subunit 15 0.00637287
C5ORF28 chromosome 5 open reading frame 28 0.00636559
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.00636372
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 0.00635976
SPTSSA serine palmitoyltransferase, small subunit A 0.00635679
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) 0.00635472
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 0.00633132
PDCD10 programmed cell death 10 0.00632874
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 0.00632579
GSTA1 glutathione S-transferase alpha 1 0.00631689
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.00631348
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.00630867
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.00626702
AK4 adenylate kinase 4 0.00626337
ASF1A anti-silencing function 1A histone chaperone 0.00625258
NINJ2 ninjurin 2 0.00625247
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 0.00624547
SAP30 Sin3A-associated protein, 30kDa 0.00624395
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.00623395
PEX2 peroxisomal biogenesis factor 2 0.0062281
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00621698
MRPL39 mitochondrial ribosomal protein L39 0.00621372
SRGN serglycin 0.00620308
C1ORF174 chromosome 1 open reading frame 174 0.00618919
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.00618022
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.00617868
SPARCL1 SPARC-like 1 (hevin) 0.00617487
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.00617125

decreased expression

Symbol Name Standardized Value
AMIGO2 adhesion molecule with Ig-like domain 2 -0.020086
MX1 MX dynamin-like GTPase 1 -0.0187221
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.0164907
HSPA1A heat shock 70kDa protein 1A -0.01579
LAMB3 laminin, beta 3 -0.0145498
ISG15 ISG15 ubiquitin-like modifier -0.0142039
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.0139734
BTG2 BTG family, member 2 -0.0137366
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0135198
LAMC2 laminin, gamma 2 -0.0134533
IFI6 interferon, alpha-inducible protein 6 -0.0134453
HMOX1 heme oxygenase 1 -0.0131769
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.013103
KRT7 keratin 7, type II -0.012509
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.0125045
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.0124889
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.0124625
MVP major vault protein -0.0122983
IFI44L interferon-induced protein 44-like -0.0122391
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.0121126
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.0121055
IRS2 insulin receptor substrate 2 -0.0119844
PTPRE protein tyrosine phosphatase, receptor type, E -0.0117924
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.0115045
SIK1 salt-inducible kinase 1 -0.0114713
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.0114567
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.0112531
TFPI2 tissue factor pathway inhibitor 2 -0.0111806
OSBPL10 oxysterol binding protein-like 10 -0.0111434
MFAP5 microfibrillar associated protein 5 -0.0109628
TGFA transforming growth factor, alpha -0.010873
MYRF myelin regulatory factor -0.0107898
NT5E 5'-nucleotidase, ecto (CD73) -0.0106232
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.0105568
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.0104689
TRIM22 tripartite motif containing 22 -0.0103969
FN1 fibronectin 1 -0.0103912
KYNU kynureninase -0.0103416
FILIP1L filamin A interacting protein 1-like -0.010309
WDR7 WD repeat domain 7 -0.0102511
CXCL5 chemokine (C-X-C motif) ligand 5 -0.0102437
DOCK9 dedicator of cytokinesis 9 -0.0102338
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.0101795
AIM2 absent in melanoma 2 -0.0100247
GBP2 guanylate binding protein 2, interferon-inducible -0.010004
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0100003
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 -0.00996751
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00992157
EGR2 early growth response 2 -0.00991309
FAM50A family with sequence similarity 50, member A -0.00982463
DUSP4 dual specificity phosphatase 4 -0.00979919
ZMAT3 zinc finger, matrin-type 3 -0.00976732
CCN2 cellular communication network factor 2 -0.00975352
AKAP12 A kinase (PRKA) anchor protein 12 -0.00975202
PLAAT3 phospholipase A and acyltransferase 3 -0.00972137
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00961153
MX2 MX dynamin-like GTPase 2 -0.00954793
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.00948076
STAT1 signal transducer and activator of transcription 1, 91kDa -0.00946916
KLF6 Kruppel-like factor 6 -0.00946264
IGF2R insulin-like growth factor 2 receptor -0.0094191
TGFBI transforming growth factor, beta-induced, 68kDa -0.00929023
IRF9 interferon regulatory factor 9 -0.00920959
FOXO1 forkhead box O1 -0.00920725
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00920284
ZFPM2 zinc finger protein, FOG family member 2 -0.00912594
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00908341
EIF5A eukaryotic translation initiation factor 5A -0.00905787
IFI16 interferon, gamma-inducible protein 16 -0.00905587
NAGK N-acetylglucosamine kinase -0.00905445
SFRP4 secreted frizzled-related protein 4 -0.00900827
PDZK1IP1 PDZK1 interacting protein 1 -0.00900729
GSDME gasdermin E -0.00900388
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 -0.00900147
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.00894699
NVL nuclear VCP-like -0.00891168
SAMD9 sterile alpha motif domain containing 9 -0.0089018
IFI44 interferon-induced protein 44 -0.00886733
ANO1 anoctamin 1, calcium activated chloride channel -0.0088629
IFI27 interferon, alpha-inducible protein 27 -0.00878736
TFF1 trefoil factor 1 -0.00877864
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00874946
XIC X chromosome inactivation center -0.00871671
PFKP phosphofructokinase, platelet -0.00869763
MGLL monoglyceride lipase -0.00867809
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00864966
MMP7 matrix metallopeptidase 7 -0.00864158
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00862338
PLXNB2 plexin B2 -0.00855282
C8ORF4 chromosome 8 open reading frame 4 -0.00852405
MAP7D1 MAP7 domain containing 1 -0.00852151
XAF1 XIAP associated factor 1 -0.00847655
SFRP1 secreted frizzled-related protein 1 -0.0084518
CARD10 caspase recruitment domain family, member 10 -0.00843082
COL9A2 collagen, type IX, alpha 2 -0.00843026
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00839207
MLXIP MLX interacting protein -0.00839004
RRAD Ras-related associated with diabetes -0.00836172
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.00834631
PSAP prosaposin -0.00831855
CD163 CD163 molecule -0.00828865
HBEGF heparin-binding EGF-like growth factor -0.00828358
ISG20 interferon stimulated exonuclease gene 20kDa -0.00826877
TXNRD1 thioredoxin reductase 1 -0.00825225
FADS3 fatty acid desaturase 3 -0.00824073
SIRPA signal-regulatory protein alpha -0.00821274
EGR1 early growth response 1 -0.00818747
PLPP2 phospholipid phosphatase 2 -0.00818664
CCND3 cyclin D3 -0.00817554
GREM1 gremlin 1, DAN family BMP antagonist -0.00816994
MLPH melanophilin -0.00813968
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.00812957
ACADVL acyl-CoA dehydrogenase, very long chain -0.00812354
MOCOS molybdenum cofactor sulfurase -0.00811888
TGM2 transglutaminase 2 -0.00811681
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -0.00809281
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -0.00807627
C3 complement component 3 -0.00807254
MET MET proto-oncogene, receptor tyrosine kinase -0.00804544
DST dystonin -0.00803966
LBH limb bud and heart development -0.00803599
APOD apolipoprotein D -0.00802643
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00801057
PCDH9 protocadherin 9 -0.00800135
CTSL cathepsin L -0.0079951
NBPF10 neuroblastoma breakpoint family, member 10 -0.00797465
SP110 SP110 nuclear body protein -0.00796259
EFNA1 ephrin-A1 -0.00795921
MYO6 myosin VI -0.00794335
INHBA inhibin, beta A -0.0079017
GRK5 G protein-coupled receptor kinase 5 -0.00784678
TUBB6 tubulin, beta 6 class V -0.00783675
CRYAB crystallin, alpha B -0.00782029
COL11A1 collagen, type XI, alpha 1 -0.00781722
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -0.00781475
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -0.00780151
PLAU plasminogen activator, urokinase -0.00777107
FHL2 four and a half LIM domains 2 -0.00776323
SQSTM1 sequestosome 1 -0.00775962
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00775705
TNIP1 TNFAIP3 interacting protein 1 -0.00773919
BHLHE41 basic helix-loop-helix family, member e41 -0.00773554
BIK BCL2-interacting killer (apoptosis-inducing) -0.00767421
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene -0.00767164
GOLGB1 golgin B1 -0.00765956
LPP LIM domain containing preferred translocation partner in lipoma -0.00764415
AXL AXL receptor tyrosine kinase -0.00763755
MEF2C myocyte enhancer factor 2C -0.00763505
COL15A1 collagen, type XV, alpha 1 -0.00762869
IRS1 insulin receptor substrate 1 -0.00758283
ELF4 E74-like factor 4 (ets domain transcription factor) -0.00757396
BST2 bone marrow stromal cell antigen 2 -0.00753499
CEMIP2 cell migration inducing hyaluronidase 2 -0.00753446
RIN2 Ras and Rab interactor 2 -0.00752323
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.00751633
MXRA5 matrix-remodelling associated 5 -0.00751137
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00750601
FGD6 FYVE, RhoGEF and PH domain containing 6 -0.00749671
SYNM synemin, intermediate filament protein -0.00749641
CLDN1 claudin 1 -0.00748359
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00748028
MAGEA3 melanoma antigen family A3 -0.00747317
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -0.00745965
JAK1 Janus kinase 1 -0.00744817
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.00741591
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.0074053
IGF1R insulin-like growth factor 1 receptor -0.0074046
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00739916
WSB1 WD repeat and SOCS box containing 1 -0.00739236
MACF1 microtubule-actin crosslinking factor 1 -0.00738571
TNNC1 troponin C type 1 (slow) -0.00735315
NAV2 neuron navigator 2 -0.00734662
SAMD4A sterile alpha motif domain containing 4A -0.00733664
HOMER3 homer scaffolding protein 3 -0.00730002
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -0.00728233
CUX1 cut-like homeobox 1 -0.00727826
EIF6 eukaryotic translation initiation factor 6 -0.0072676
METRN meteorin, glial cell differentiation regulator -0.00726709
FHOD3 formin homology 2 domain containing 3 -0.0072492
YBX3 Y box binding protein 3 -0.00723072
HOXB7 homeobox B7 -0.00723053
WARS1 tryptophanyl-tRNA synthetase 1 -0.00722032
LAMA3 laminin, alpha 3 -0.00721762
STX4 syntaxin 4 -0.00721405
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00720796
GOLGA8A golgin A8 family, member A -0.00717443
APOL1 apolipoprotein L, 1 -0.0071563
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -0.00714836
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -0.00712014
DOCK4 dedicator of cytokinesis 4 -0.00711185
INAVA innate immunity activator -0.00711065
MTUS1 microtubule associated tumor suppressor 1 -0.00711033
BAG3 BCL2-associated athanogene 3 -0.00710495
CD70 CD70 molecule -0.00710406
IER5 immediate early response 5 -0.00710042
CYBB cytochrome b-245, beta polypeptide -0.00709166
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00708841
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00708299
EPHA2 EPH receptor A2 -0.00707584
IFIH1 interferon induced with helicase C domain 1 -0.00701994
PLXNA1 plexin A1 -0.00701694
THBS2 thrombospondin 2 -0.00698861
QKI QKI, KH domain containing, RNA binding -0.0069578
ACTG2 actin, gamma 2, smooth muscle, enteric -0.00694772
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00694502
VLDLR very low density lipoprotein receptor -0.00694496
FA2H fatty acid 2-hydroxylase -0.00693364
EHD3 EH-domain containing 3 -0.00692182
CDCP1 CUB domain containing protein 1 -0.00691191
MYH11 myosin, heavy chain 11, smooth muscle -0.0068831
SRPX sushi-repeat containing protein, X-linked -0.0068818
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 -0.00686804
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 -0.00686228
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -0.00685081
IL32 interleukin 32 -0.00684603
AHNAK2 AHNAK nucleoprotein 2 -0.00684103
JAK2 Janus kinase 2 -0.00683566
ASPN asporin -0.00683202
IRF7 interferon regulatory factor 7 -0.00682624
MYOF myoferlin -0.00682578
COPG1 coatomer protein complex, subunit gamma 1 -0.00682218
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -0.00681841
VNN1 vanin 1 -0.00678568
MEAK7 MTOR associated protein, eak-7 homolog -0.00678563
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0067787
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00677774
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.00675652
EIF5B eukaryotic translation initiation factor 5B -0.00675462
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.0067543
HIP1R huntingtin interacting protein 1 related -0.0067456
L1CAM L1 cell adhesion molecule -0.00674225
LRP4 low density lipoprotein receptor-related protein 4 -0.00673631
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.0067263
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00668242
HSPH1 heat shock 105kDa/110kDa protein 1 -0.00668023
KIAA0930 KIAA0930 -0.00667913
FOSL2 FOS-like antigen 2 -0.00667566
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00664342
COL7A1 collagen, type VII, alpha 1 -0.00664215
GPR137B G protein-coupled receptor 137B -0.00663266
MITF microphthalmia-associated transcription factor -0.00663142
SPATA20 spermatogenesis associated 20 -0.00662971
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00662844
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 -0.00662048
TYMP thymidine phosphorylase -0.00661859
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -0.00661732
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -0.00661728
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00661234