| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cullin 3|This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012] (NCBI Entrez Gene Database, 8452) |
| External Link | https://ncbi.nlm.nih.gov/gene/8452 |
| Similar Terms | |
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499 genes differentially expressed following the CUL3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.0127622 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0121428 |
| SFN | stratifin | 0.0115433 |
| IL32 | interleukin 32 | 0.0105403 |
| KYNU | kynureninase | 0.0104668 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.0104096 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0103353 |
| S100A9 | S100 calcium binding protein A9 | 0.0103182 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.0102326 |
| FOSL1 | FOS-like antigen 1 | 0.00990906 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00984709 |
| LTF | lactotransferrin | 0.00979045 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00956336 |
| TXNRD1 | thioredoxin reductase 1 | 0.00952969 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00942825 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00942451 |
| HOPX | HOP homeobox | 0.00931812 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.0089219 |
| HMOX1 | heme oxygenase 1 | 0.00888798 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00881533 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00875709 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | 0.00868764 |
| CD52 | CD52 molecule | 0.00859995 |
| KRT6A | keratin 6A, type II | 0.00857009 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.00851068 |
| TRIM16 | tripartite motif containing 16 | 0.00850429 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00849395 |
| KLF9 | Kruppel-like factor 9 | 0.00849388 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.00838742 |
| CSTA | cystatin A (stefin A) | 0.00835863 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00833465 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00826752 |
| TRAF1 | TNF receptor-associated factor 1 | 0.00825628 |
| S100A8 | S100 calcium binding protein A8 | 0.00822121 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00817138 |
| S100P | S100 calcium binding protein P | 0.00812081 |
| NAV3 | neuron navigator 3 | 0.00811069 |
| SPRR1B | small proline-rich protein 1B | 0.00809644 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00806058 |
| S100A2 | S100 calcium binding protein A2 | 0.00806049 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00806039 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00804666 |
| ITK | IL2-inducible T-cell kinase | 0.0080209 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00798008 |
| GCH1 | GTP cyclohydrolase 1 | 0.00796168 |
| ABLIM1 | actin binding LIM protein 1 | 0.00793073 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00788148 |
| LYPD3 | LY6/PLAUR domain containing 3 | 0.00788034 |
| BCL2A1 | BCL2-related protein A1 | 0.0078548 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00773056 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00771561 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00771492 |
| IL1RN | interleukin 1 receptor antagonist | 0.00771387 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00765429 |
| CD69 | CD69 molecule | 0.00762219 |
| CLU | clusterin | 0.00761673 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.00756835 |
| ACOT9 | acyl-CoA thioesterase 9 | 0.00745494 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.0073929 |
| TPM4 | tropomyosin 4 | 0.00735674 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.00732535 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00731371 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.00728851 |
| ADRB2 | adrenoceptor beta 2, surface | 0.00725718 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00718422 |
| GPX2 | glutathione peroxidase 2 | 0.00714089 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00705754 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00704818 |
| RIT1 | Ras-like without CAAX 1 | 0.00702649 |
| SMAD3 | SMAD family member 3 | 0.007021 |
| KRT14 | keratin 14, type I | 0.00699723 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00699175 |
| LAMC2 | laminin, gamma 2 | 0.00697098 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00693817 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0069179 |
| PNMA1 | paraneoplastic Ma antigen 1 | 0.00690795 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00690003 |
| DUSP14 | dual specificity phosphatase 14 | 0.00688671 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.00688409 |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.00682647 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00680099 |
| LYRM4 | LYR motif containing 4 | 0.00677999 |
| RHOF | ras homolog family member F (in filopodia) | 0.0067396 |
| AK4 | adenylate kinase 4 | 0.00673592 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00671801 |
| IL7R | interleukin 7 receptor | 0.00669971 |
| ATF3 | activating transcription factor 3 | 0.00667253 |
| SLC38A6 | solute carrier family 38, member 6 | 0.00665785 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00661698 |
| GPR65 | G protein-coupled receptor 65 | 0.00660848 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00658507 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0065606 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 0.00655977 |
| C1S | complement component 1, s subcomponent | 0.00654149 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.00654023 |
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) | 0.00653992 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | 0.00653681 |
| PRAME | preferentially expressed antigen in melanoma | 0.00653081 |
| MREG | melanoregulin | 0.00650795 |
| ODC1 | ornithine decarboxylase 1 | 0.00649497 |
| CST7 | cystatin F (leukocystatin) | 0.00644975 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.00644848 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.00644771 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00642741 |
| CTTN | cortactin | 0.00642519 |
| DCTPP1 | dCTP pyrophosphatase 1 | 0.00642444 |
| TRIM14 | tripartite motif containing 14 | 0.00640886 |
| CENPU | centromere protein U | 0.00640126 |
| NOX4 | NADPH oxidase 4 | 0.00634105 |
| CHI3L2 | chitinase 3-like 2 | 0.00632494 |
| UCK2 | uridine-cytidine kinase 2 | 0.00631276 |
| CD2 | CD2 molecule | 0.00631071 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 0.0063092 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | 0.00630715 |
| SPRR2B | small proline-rich protein 2B | 0.0062933 |
| COCH | cochlin | 0.00628774 |
| KLHL21 | kelch-like family member 21 | 0.00628275 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.00628134 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing | 0.00627786 |
| CALML5 | calmodulin-like 5 | 0.00627645 |
| ADM | adrenomedullin | 0.00626476 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.00625506 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 0.0062506 |
| MMP9 | matrix metallopeptidase 9 | 0.00624176 |
| RRP15 | ribosomal RNA processing 15 homolog (S. cerevisiae) | 0.00622166 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.0062206 |
| DUSP5 | dual specificity phosphatase 5 | 0.00621276 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.0061894 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00618928 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00615646 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00613943 |
| APOBEC3A | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A | 0.00613178 |
| KRT17 | keratin 17, type I | 0.0061148 |
| WT1 | Wilms tumor 1 | 0.00610869 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00609655 |
| EMP3 | epithelial membrane protein 3 | 0.00608464 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.00607802 |
| HOXB7 | homeobox B7 | 0.00605659 |
| FADD | Fas (TNFRSF6)-associated via death domain | 0.00605439 |
| KRT6B | keratin 6B, type II | 0.00604386 |
| CD96 | CD96 molecule | 0.00604231 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.00602575 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00602 |
| INHBA | inhibin, beta A | 0.00601862 |
| TARP | TCR gamma alternate reading frame protein | 0.00601639 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00601626 |
| GPER1 | G protein-coupled estrogen receptor 1 | 0.005933 |
| HDDC2 | HD domain containing 2 | 0.00591968 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00591554 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.00591119 |
| SCRG1 | stimulator of chondrogenesis 1 | 0.00590296 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.0059007 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.00589678 |
| HBD | hemoglobin, delta | 0.00588776 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00584799 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | 0.00584391 |
| FYB1 | FYN binding protein 1 | 0.00581037 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.00580354 |
| TPD52 | tumor protein D52 | 0.00579972 |
| GPR137B | G protein-coupled receptor 137B | 0.00579948 |
| GIMAP4 | GTPase, IMAP family member 4 | 0.00579503 |
| S100A7 | S100 calcium binding protein A7 | 0.00578322 |
| GSTO1 | glutathione S-transferase omega 1 | 0.00578288 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.0057785 |
| SLN | sarcolipin | 0.00577231 |
| TMEM14A | transmembrane protein 14A | 0.00575624 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 | 0.00574845 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00572037 |
| BAG2 | BCL2-associated athanogene 2 | 0.00571804 |
| CRTAM | cytotoxic and regulatory T cell molecule | 0.00569874 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | 0.00568623 |
| NPR3 | natriuretic peptide receptor 3 | 0.00568362 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | 0.00566788 |
| HMGA1 | high mobility group AT-hook 1 | 0.00566736 |
| HIRA | histone cell cycle regulator | 0.00564987 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.00563388 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00562827 |
| GSTA4 | glutathione S-transferase alpha 4 | 0.00562163 |
| LIF | leukemia inhibitory factor | 0.00561193 |
| NXT2 | nuclear transport factor 2-like export factor 2 | 0.0056108 |
| PTHLH | parathyroid hormone-like hormone | 0.00558582 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00558204 |
| LGALSL | lectin, galactoside-binding-like | 0.00555599 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00554085 |
| SPRR1A | small proline-rich protein 1A | 0.00553146 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00552593 |
| ARL4A | ADP-ribosylation factor-like 4A | 0.00552389 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 0.00551983 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00550137 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00549687 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.00549669 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00547742 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | 0.0054766 |
| MIR22HG | MIR22 host gene | 0.00547457 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00547161 |
| KRT81 | keratin 81, type II | 0.00546246 |
| CTSW | cathepsin W | 0.00545976 |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) | 0.0054595 |
| PIR | pirin (iron-binding nuclear protein) | 0.00545551 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.00544367 |
| COG5 | component of oligomeric golgi complex 5 | 0.00544023 |
| NXT1 | nuclear transport factor 2-like export factor 1 | 0.00543739 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.00543376 |
| GATA6 | GATA binding protein 6 | 0.00542624 |
| KRT10 | keratin 10, type I | 0.00542328 |
| JUNB | jun B proto-oncogene | 0.00540025 |
| FOXO1 | forkhead box O1 | 0.00539897 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.00539339 |
| SPHK1 | sphingosine kinase 1 | 0.00538012 |
| POSTN | periostin, osteoblast specific factor | 0.00536864 |
| PFKP | phosphofructokinase, platelet | 0.00535621 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00533871 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00532559 |
| CD84 | CD84 molecule | 0.0053227 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.0053206 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.00531041 |
| WDR61 | WD repeat domain 61 | 0.00529724 |
| SERTAD2 | SERTA domain containing 2 | 0.00526259 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00525973 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 0.00525307 |
| HPGDS | hematopoietic prostaglandin D synthase | 0.00523026 |
| GPR18 | G protein-coupled receptor 18 | 0.00521933 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.00521516 |
| REXO2 | RNA exonuclease 2 | 0.00521018 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00520553 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00520395 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 0.00519493 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00519159 |
| IER2 | immediate early response 2 | 0.00518835 |
| NRN1 | neuritin 1 | 0.0051837 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00516852 |
| TAF9 | TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa | 0.00516228 |
| ADA | adenosine deaminase | 0.00516068 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.00515796 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00515486 |
| ABHD4 | abhydrolase domain containing 4 | 0.00514457 |
| CCNB1 | cyclin B1 | 0.00514382 |
| CD48 | CD48 molecule | 0.00512109 |
| C1ORF115 | chromosome 1 open reading frame 115 | 0.00511663 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00510877 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa | 0.00509315 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | 0.00508764 |
| ASB13 | ankyrin repeat and SOCS box containing 13 | 0.0050832 |
| IL18 | interleukin 18 | 0.00508101 |
| EPHA2 | EPH receptor A2 | 0.00507311 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00506465 |
| HDAC9 | histone deacetylase 9 | 0.00506235 |
| EHD1 | EH-domain containing 1 | 0.00505894 |
| ACTN1 | actinin, alpha 1 | 0.00505758 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BEX1 | brain expressed, X-linked 1 | -0.012387 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.0115584 |
| RGS5 | regulator of G-protein signaling 5 | -0.0114645 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0112245 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0103097 |
| XPO7 | exportin 7 | -0.0101789 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00973737 |
| METTL7A | methyltransferase like 7A | -0.00968897 |
| OLFM4 | olfactomedin 4 | -0.00947864 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00939581 |
| DTX4 | deltex 4, E3 ubiquitin ligase | -0.00906967 |
| PROM1 | prominin 1 | -0.00897875 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.0089744 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | -0.00872395 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00866637 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00857011 |
| ITM2C | integral membrane protein 2C | -0.00852875 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.00828716 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.0082833 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00825326 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.0082466 |
| INSR | insulin receptor | -0.00822388 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.00815676 |
| WASHC4 | WASH complex subunit 4 | -0.0078374 |
| ASRGL1 | asparaginase like 1 | -0.00778313 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.00760116 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.00759979 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.00747079 |
| TRIM2 | tripartite motif containing 2 | -0.00734316 |
| SLC35E2B | solute carrier family 35, member E2B | -0.00732187 |
| STC1 | stanniocalcin 1 | -0.00730673 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.0072497 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00720957 |
| DAPK1 | death-associated protein kinase 1 | -0.00719071 |
| ZNF423 | zinc finger protein 423 | -0.00714466 |
| WDTC1 | WD and tetratricopeptide repeats 1 | -0.00712036 |
| BLNK | B-cell linker | -0.00707254 |
| FADS1 | fatty acid desaturase 1 | -0.00705077 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.00704605 |
| MAOA | monoamine oxidase A | -0.00703152 |
| TM7SF2 | transmembrane 7 superfamily member 2 | -0.00693723 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00692924 |
| SCPEP1 | serine carboxypeptidase 1 | -0.00691972 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00690822 |
| MEIS1 | Meis homeobox 1 | -0.00689636 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00683577 |
| PRDX2 | peroxiredoxin 2 | -0.00683034 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00679505 |
| FTO | fat mass and obesity associated | -0.00677986 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | -0.00674454 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00673254 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00671918 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00667611 |
| FCGBP | Fc fragment of IgG binding protein | -0.00665354 |
| PLLP | plasmolipin | -0.00664803 |
| GPSM2 | G-protein signaling modulator 2 | -0.00661706 |
| KIF1A | kinesin family member 1A | -0.00661142 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00660565 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00659321 |
| NBEA | neurobeachin | -0.00657309 |
| HMGB3 | high mobility group box 3 | -0.00656899 |
| GOLGA8H | golgin A8 family, member H | -0.0065635 |
| H1-2 | H1.2 linker histone, cluster member | -0.0065564 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.00655119 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00653116 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | -0.00644828 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00644149 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00641754 |
| TFF1 | trefoil factor 1 | -0.00641644 |
| ARG2 | arginase 2 | -0.00637816 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.00635729 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0063361 |
| PRODH | proline dehydrogenase (oxidase) 1 | -0.00630263 |
| L1CAM | L1 cell adhesion molecule | -0.00629402 |
| AFF1 | AF4/FMR2 family, member 1 | -0.00628987 |
| PCDH9 | protocadherin 9 | -0.00626673 |
| CPNE1 | copine I | -0.00623503 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00623163 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.0062155 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | -0.00621242 |
| HSD17B4 | hydroxysteroid (17-beta) dehydrogenase 4 | -0.00621078 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.00620022 |
| USP22 | ubiquitin specific peptidase 22 | -0.00619473 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00619292 |
| GLG1 | golgi glycoprotein 1 | -0.00619022 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.00618561 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | -0.00616744 |
| GOLM1 | golgi membrane protein 1 | -0.00613162 |
| XIC | X chromosome inactivation center | -0.00612521 |
| RSRP1 | arginine/serine-rich protein 1 | -0.00612286 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00611469 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | -0.00610583 |
| NPTX2 | neuronal pentraxin II | -0.00610326 |
| PAIP2B | poly(A) binding protein interacting protein 2B | -0.00607285 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00604802 |
| WNT5B | wingless-type MMTV integration site family, member 5B | -0.00602848 |
| FAM111A | family with sequence similarity 111, member A | -0.00600435 |
| TXLNA | taxilin alpha | -0.00600151 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) | -0.00597774 |
| OPHN1 | oligophrenin 1 | -0.00597249 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00596282 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.00595037 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00590342 |
| ADD3 | adducin 3 (gamma) | -0.00589726 |
| FNBP1L | formin binding protein 1-like | -0.00589201 |
| PEG3 | paternally expressed 3 | -0.00588917 |
| OLFM1 | olfactomedin 1 | -0.00588094 |
| RTN3 | reticulon 3 | -0.00587984 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00586735 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.00585085 |
| C9ORF3 | chromosome 9 open reading frame 3 | -0.00582814 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00581636 |
| ACAD8 | acyl-CoA dehydrogenase family, member 8 | -0.00581532 |
| MST1 | macrophage stimulating 1 | -0.00581039 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00578611 |
| NARF | nuclear prelamin A recognition factor | -0.00577164 |
| ISL1 | ISL LIM homeobox 1 | -0.00576221 |
| REG1A | regenerating islet-derived 1 alpha | -0.00575848 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00575512 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00575443 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | -0.00574604 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00572638 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0057263 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0057178 |
| HYOU1 | hypoxia up-regulated 1 | -0.00571329 |
| SARAF | store-operated calcium entry-associated regulatory factor | -0.00571015 |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | -0.00569293 |
| DLG3 | discs, large homolog 3 (Drosophila) | -0.00569219 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00568539 |
| TUBA1A | tubulin, alpha 1a | -0.00567857 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.00567382 |
| THYN1 | thymocyte nuclear protein 1 | -0.00563966 |
| MAGED1 | melanoma antigen family D1 | -0.00563888 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | -0.00563696 |
| LDB2 | LIM domain binding 2 | -0.00563668 |
| CTBP2 | C-terminal binding protein 2 | -0.00562036 |
| PDE10A | phosphodiesterase 10A | -0.00561723 |
| CALCA | calcitonin-related polypeptide alpha | -0.00561132 |
| POU2AF1 | POU class 2 associating factor 1 | -0.00558425 |
| HOXC6 | homeobox C6 | -0.0055794 |
| LAMB1 | laminin, beta 1 | -0.00557697 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.00556584 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00555372 |
| HDLBP | high density lipoprotein binding protein | -0.00554691 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -0.00554554 |
| MGP | matrix Gla protein | -0.00552459 |
| CPE | carboxypeptidase E | -0.00551335 |
| PXDN | peroxidasin | -0.00550634 |
| PEG10 | paternally expressed 10 | -0.00548478 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00547466 |
| MXRA8 | matrix-remodelling associated 8 | -0.00546886 |
| NLGN4X | neuroligin 4, X-linked | -0.00545689 |
| CCNL2 | cyclin L2 | -0.00545389 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.00545004 |
| IPO13 | importin 13 | -0.00543823 |
| CCNF | cyclin F | -0.00542537 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.00538764 |
| PNMA8A | PNMA family member 8A | -0.00538085 |
| CBX5 | chromobox homolog 5 | -0.00536731 |
| FOXN3 | forkhead box N3 | -0.00535301 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.00535255 |
| RRBP1 | ribosome binding protein 1 | -0.00534203 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00534039 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.00532973 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00532325 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00532299 |
| WFS1 | Wolfram syndrome 1 (wolframin) | -0.0053163 |
| TTC39A | tetratricopeptide repeat domain 39A | -0.00530163 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00528984 |
| BRD8 | bromodomain containing 8 | -0.00528637 |
| MEN1 | multiple endocrine neoplasia I | -0.00526292 |
| RET | ret proto-oncogene | -0.0052404 |
| GAS6 | growth arrest-specific 6 | -0.0052237 |
| CD200 | CD200 molecule | -0.00521511 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00520703 |
| CIT | citron rho-interacting serine/threonine kinase | -0.00519518 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | -0.00518237 |
| MSLN | mesothelin | -0.00517619 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | -0.00517617 |
| CHGB | chromogranin B | -0.00516072 |
| IK | IK cytokine, down-regulator of HLA II | -0.00514186 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.00514152 |
| FABP6 | fatty acid binding protein 6, ileal | -0.00513102 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00513071 |
| TSPAN13 | tetraspanin 13 | -0.00510189 |
| TECR | trans-2,3-enoyl-CoA reductase | -0.00509638 |
| CIRBP | cold inducible RNA binding protein | -0.00509373 |
| NKX2-1 | NK2 homeobox 1 | -0.00508926 |
| DEFB1 | defensin, beta 1 | -0.00507883 |
| ASS1 | argininosuccinate synthase 1 | -0.00506043 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | -0.00506016 |
| VPS51 | vacuolar protein sorting 51 homolog (S. cerevisiae) | -0.00505817 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.00504893 |
| SLC43A3 | solute carrier family 43, member 3 | -0.00504387 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | -0.00504274 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | -0.00503757 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.00503756 |
| UFL1 | UFM1-specific ligase 1 | -0.00503302 |
| TNS1 | tensin 1 | -0.00503297 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | -0.00502569 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.00502499 |
| HMGB1 | high mobility group box 1 | -0.00502023 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00501876 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.00501595 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00501401 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.00501053 |
| NID2 | nidogen 2 (osteonidogen) | -0.00500324 |
| TMEM243 | transmembrane protein 243, mitochondrial | -0.00497276 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00497137 |
| HRASLS | HRAS-like suppressor | -0.00496821 |
| SERINC5 | serine incorporator 5 | -0.00496715 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.00496427 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0049642 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.00496352 |
| CYB5R2 | cytochrome b5 reductase 2 | -0.00496064 |
| LONP2 | lon peptidase 2, peroxisomal | -0.00495685 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 | -0.00495087 |
| ZNF638 | zinc finger protein 638 | -0.00494034 |
| RAB2A | RAB2A, member RAS oncogene family | -0.00491457 |
| TTR | transthyretin | -0.00490114 |
| INHBE | inhibin, beta E | -0.00488663 |
| GOLGA8A | golgin A8 family, member A | -0.00487632 |
| WLS | wntless Wnt ligand secretion mediator | -0.00486698 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00486576 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | -0.00486454 |
| ESRP2 | epithelial splicing regulatory protein 2 | -0.00485735 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.00483027 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00482974 |
| JAK1 | Janus kinase 1 | -0.00482256 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00481714 |
| TXNIP | thioredoxin interacting protein | -0.00481508 |
| RAB5B | RAB5B, member RAS oncogene family | -0.00481087 |
| PSCA | prostate stem cell antigen | -0.00481051 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.00480863 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -0.00479513 |
| FGL1 | fibrinogen-like 1 | -0.00479251 |
| AURKAIP1 | aurora kinase A interacting protein 1 | -0.00478754 |
| SNX7 | sorting nexin 7 | -0.00478679 |
| ETNPPL | ethanolamine-phosphate phospho-lyase | -0.00477907 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00477313 |
| BRINP1 | bone morphogenetic protein/retinoic acid inducible neural-specific 1 | -0.00477244 |
| CAMLG | calcium modulating ligand | -0.00477194 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.00476833 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -0.00476383 |
| NANOG | Nanog homeobox | -0.00474778 |
| TMEM47 | transmembrane protein 47 | -0.00474521 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00474004 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.00473188 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00472978 |
| SUOX | sulfite oxidase | -0.00471178 |
