CUL7 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description cullin 7|The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009] (NCBI Entrez Gene Database, 9820)
External Link http://www.ncbi.nlm.nih.gov/gene/9820
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120 interacting proteins for CUL7 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
AMOTL1 angiomotin like 1
ANAPC1 anaphase promoting complex subunit 1
ANAPC5 anaphase promoting complex subunit 5
ARF1 ADP-ribosylation factor 1
ARHGAP12 Rho GTPase activating protein 12
ASB2 ankyrin repeat and SOCS box containing 2
BAG2 BCL2-associated athanogene 2
BAG6 BCL2-associated athanogene 6
CCDC8 coiled-coil domain containing 8
CCND1 cyclin D1
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEP250 centrosomal protein 250kDa
COLGALT1 collagen beta(1-O)galactosyltransferase 1
COMMD1 copper metabolism (Murr1) domain containing 1
COPS4 COP9 signalosome subunit 4
CPVL carboxypeptidase, vitellogenic-like
CUL1 cullin 1
CUL2 cullin 2
CUL9 cullin 9
DCAF7 DDB1 and CUL4 associated factor 7
DUSP9 dual specificity phosphatase 9
EEF2 eukaryotic translation elongation factor 2
ERCC6 excision repair cross-complementation group 6
FBXL16 F-box and leucine-rich repeat protein 16
FBXO2 F-box protein 2
FBXW8 F-box and WD repeat domain containing 8
GRB2 growth factor receptor-bound protein 2
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
INADL InaD-like (Drosophila)
IRS1 insulin receptor substrate 1
LARP1 La ribonucleoprotein domain family, member 1
LATS2 large tumor suppressor kinase 2
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LNX2 ligand of numb-protein X 2
LONP1 lon peptidase 1, mitochondrial
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAPK11 mitogen-activated protein kinase 11
MAPK14 mitogen-activated protein kinase 14
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEGF10 multiple EGF-like-domains 10
MKNK1 MAP kinase interacting serine/threonine kinase 1
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MOB1A MOB kinase activator 1A
MPDZ multiple PDZ domain protein
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MRPL13 mitochondrial ribosomal protein L13
MRPL52 mitochondrial ribosomal protein L52
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
OBSL1 obscurin-like 1
OLA1 Obg-like ATPase 1
PABPC1 poly(A) binding protein, cytoplasmic 1
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PARD3 par-3 family cell polarity regulator
PDCD5 programmed cell death 5
PFDN5 prefoldin subunit 5
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PLXNB3 plexin B3
PNMA2 paraneoplastic Ma antigen 2
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PYCRL pyrroline-5-carboxylate reductase-like
RABGAP1 RAB GTPase activating protein 1
RBX1 ring-box 1, E3 ubiquitin protein ligase
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RPL5 ribosomal protein L5
SF3B2 splicing factor 3b, subunit 2, 145kDa
SF3B3 splicing factor 3b, subunit 3, 130kDa
SIRT7 sirtuin 7
SKP1 S-phase kinase-associated protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SMG5 SMG5 nonsense mediated mRNA decay factor
SMG7 SMG7 nonsense mediated mRNA decay factor
SOX2 SRY (sex determining region Y)-box 2
STXBP4 syntaxin binding protein 4
TCP1 t-complex 1
TDRD12 tudor domain containing 12
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TRAF1 TNF receptor-associated factor 1
TRIP13 thyroid hormone receptor interactor 13
TSPAN10 tetraspanin 10
TSPYL4 TSPY-like 4
TUBB tubulin, beta class I
TUBB2A tubulin, beta 2A class IIa
TUBB3 tubulin, beta 3 class III
TUBB6 tubulin, beta 6 class V
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBC ubiquitin C
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2M ubiquitin-conjugating enzyme E2M
USP28 ubiquitin specific peptidase 28
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
USP9X ubiquitin specific peptidase 9, X-linked
UTRN utrophin
VARS valyl-tRNA synthetase
VBP1 von Hippel-Lindau binding protein 1
VCP valosin containing protein
YBX1 Y box binding protein 1
YBX3 Y box binding protein 3
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta