CX3CL1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description chemokine (C-X3-C motif) ligand 1| (NCBI Entrez Gene Database, 6376)
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Genes

328 genes differentially expressed following the CX3CL1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
CLEC12A C-type lectin domain family 12, member A 3.00015
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 3.00015
IL5RA interleukin 5 receptor, alpha 3.00015
AADACL4 arylacetamide deacetylase-like 4 3.00015
MBD3L3 methyl-CpG binding domain protein 3-like 3 3.00015
SSMEM1 serine-rich single-pass membrane protein 1 3.00015
SIGLEC5 sialic acid binding Ig-like lectin 5 3.00015
ARSF arylsulfatase F 3.00015
OTUD6A OTU deubiquitinase 6A 3.00015
ADGB androglobin 3.00015
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like 3.00015
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 3.00015
PDYN prodynorphin 3.00015
LAX1 lymphocyte transmembrane adaptor 1 3.00015
FAM167A family with sequence similarity 167, member A 3.00015
AKAP14 A kinase (PRKA) anchor protein 14 3.00015
GPR162 G protein-coupled receptor 162 3.00015
CELF6 CUGBP, Elav-like family member 6 3.00015
PLIN1 perilipin 1 3.00015
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) 3.00015
SPINK4 serine peptidase inhibitor, Kazal type 4 3.00015
FGL2 fibrinogen-like 2 3.00015
TRPV6 transient receptor potential cation channel, subfamily V, member 6 3.00015
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 3.00015
OR7A17 olfactory receptor, family 7, subfamily A, member 17 3.00015
NMUR1 neuromedin U receptor 1 3.00015
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 3.00015
HES2 hes family bHLH transcription factor 2 3.00015
ARSH arylsulfatase family, member H 3.00015
FAM161B family with sequence similarity 161, member B 3.00015
PODN podocan 3.00015
SPDEF SAM pointed domain containing ETS transcription factor 3.00015
OR5A2 olfactory receptor, family 5, subfamily A, member 2 3.00015
KRTAP13-4 keratin associated protein 13-4 3.00015
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 3.00015
SPACA7 sperm acrosome associated 7 3.00015
HMX1 H6 family homeobox 1 3.00015
DPPA3 developmental pluripotency associated 3 3.00015
S100A1 S100 calcium binding protein A1 3.00015
PNOC prepronociceptin 3.00015
SPINK14 serine peptidase inhibitor, Kazal type 14 (putative) 3.00015
HBM hemoglobin, mu 3.00015
MANEAL mannosidase, endo-alpha-like 3.00015
MMP20 matrix metallopeptidase 20 3.00015
MMP27 matrix metallopeptidase 27 3.00015
CPLX4 complexin 4 3.00015
IRX4 iroquois homeobox 4 3.00015
LINC02268 long intergenic non-protein coding RNA 2268 3.00015
SPRR2F small proline-rich protein 2F 3.00015
SPRR2E small proline-rich protein 2E 3.00015
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 3.00015
PROC protein C (inactivator of coagulation factors Va and VIIIa) 3.00015
BDKRB1 bradykinin receptor B1 3.00015
HSPA6 heat shock 70kDa protein 6 (HSP70B') 3.00015
DOK7 docking protein 7 3.00015
DOK2 docking protein 2, 56kDa 3.00015
XKR3 XK, Kell blood group complex subunit-related family, member 3 3.00015
KRT86 keratin 86, type II 3.00015
SOHLH1 spermatogenesis and oogenesis specific basic helix-loop-helix 1 3.00015
MCHR1 melanin-concentrating hormone receptor 1 3.00015
CPNE8-AS1 CPNE8 antisense RNA 1 3.00015
REELD1 reeler domain containing 1 3.00015
NHERF4 NHERF family PDZ scaffold protein 4 3.00015
LOC124903372 uncharacterized LOC124903372 3.00015
ELOA2 elongin A2 3.00015
PLAAT4 phospholipase A and acyltransferase 4 3.00015
SMIM33 small integral membrane protein 33 3.00015
PLG plasminogen 3.00015
PCDHGA9 protocadherin gamma subfamily A, 9 3.00015
LTK leukocyte receptor tyrosine kinase 3.00015
ACE2 angiotensin I converting enzyme 2 3.00015
C6 complement component 6 3.00015
RLBP1 retinaldehyde binding protein 1 3.00015
RGS9BP regulator of G protein signaling 9 binding protein 3.00015
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 3.00015
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 3.00015
CATSPERT catsper channel auxiliary subunit tau 3.00015
SIX2 SIX homeobox 2 3.00015
FOLR1 folate receptor 1 (adult) 3.00015
CD6 CD6 molecule 3.00015
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 3.00015
PTPRQ protein tyrosine phosphatase, receptor type, Q 3.00015
IRF5 interferon regulatory factor 5 3.00015
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 3.00015
C9 complement component 9 3.00015
C1QTNF9 C1q and tumor necrosis factor related protein 9 3.00015
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 3.00015
SLAMF6 SLAM family member 6 3.00015
TPTE transmembrane phosphatase with tensin homology 3.00015
TLR7 toll-like receptor 7 3.00015
SCRT2 scratch family zinc finger 2 3.00015
ZIC4 Zic family member 4 3.00015
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 3.00015
LRRD1 leucine-rich repeats and death domain containing 1 3.00015
SPINT4 serine peptidase inhibitor, Kunitz type 4 3.00015
SHISA8 shisa family member 8 3.00015
ANKRD55 ankyrin repeat domain 55 3.00015
C18ORF63 chromosome 18 open reading frame 63 3.00015
SHOX2 short stature homeobox 2 3.00015
SMIM22 small integral membrane protein 22 3.00015
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 3.00015
ZNF679 zinc finger protein 679 3.00015
OR13A1 olfactory receptor, family 13, subfamily A, member 1 3.00015
HEMGN hemogen 3.00015
MORN5 MORN repeat containing 5 3.00015
TBC1D28 TBC1 domain family, member 28 3.00015
ALOX15B arachidonate 15-lipoxygenase, type B 3.00015
C5AR2 complement component 5a receptor 2 3.00015
TECRL trans-2,3-enoyl-CoA reductase-like 3.00015
NUTM2B NUT family member 2B 3.00015
GPR61 G protein-coupled receptor 61 3.00015
ITGB7 integrin, beta 7 3.00015
CERKL ceramide kinase-like 3.00015
BTNL3 butyrophilin-like 3 3.00015
CHI3L2 chitinase 3-like 2 3.00015
HRCT1 histidine rich carboxyl terminus 1 3.00015
SNX31 sorting nexin 31 3.00015
CD52 CD52 molecule 3.00015
CD5L CD5 molecule-like 3.00015
TTC16 tetratricopeptide repeat domain 16 3.00015
RNASE11 ribonuclease, RNase A family, 11 (non-active) 3.00015
CHIT1 chitinase 1 (chitotriosidase) 3.00015
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 3.00015
CTAGE4 CTAGE family, member 4 3.00015
CRYBB3 crystallin, beta B3 3.00015
ITGA11 integrin, alpha 11 3.00015
AQP6 aquaporin 6, kidney specific 3.00015
IL19 interleukin 19 3.00015
SPANXN4 SPANX family, member N4 3.00015
POU3F3 POU class 3 homeobox 3 3.00015
MYLK2 myosin light chain kinase 2 3.00015
OR4M2 olfactory receptor, family 4, subfamily M, member 2 3.00015
CLCA4 chloride channel accessory 4 3.00015
TEX29 testis expressed 29 3.00015
FLRT3 fibronectin leucine rich transmembrane protein 3 3.00015
TMEM45B transmembrane protein 45B 3.00015
PTPN7 protein tyrosine phosphatase, non-receptor type 7 3.00015
GPRC5A G protein-coupled receptor, class C, group 5, member A 3.00015
ANGPTL3 angiopoietin-like 3 3.00015
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3.00015
TGM3 transglutaminase 3 3.00015
C10ORF105 chromosome 10 open reading frame 105 3.00015
ZPLD1 zona pellucida-like domain containing 1 3.00015
RERGL RERG/RAS-like 3.00015
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 3.00015
BTG4 B-cell translocation gene 4 3.00015
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 3.00015
AMER2 APC membrane recruitment protein 2 3.00015
PF4V1 platelet factor 4 variant 1 3.00015
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 3.00015
ICAM2 intercellular adhesion molecule 2 3.00015
NPAS4 neuronal PAS domain protein 4 3.00015
ADCY4 adenylate cyclase 4 3.00015
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2 3.00015
TRIM7 tripartite motif containing 7 3.00015
CST4 cystatin S 3.00015
SYNE2 spectrin repeat containing, nuclear envelope 2 2.97145
EMILIN1 elastin microfibril interfacer 1 2.95734
LIME1 Lck interacting transmembrane adaptor 1 2.92666
GPBP1 GC-rich promoter binding protein 1 2.92084
GPHRB golgi pH regulator B 2.91214
DHRS1 dehydrogenase/reductase (SDR family) member 1 2.89057
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma 2.89057
ZNF507 zinc finger protein 507 2.77053
TSGA10 testis specific, 10 2.76372
PTCD2 pentatricopeptide repeat domain 2 2.74723
TUBE1 tubulin, epsilon 1 2.57753
MB21D2 Mab-21 domain containing 2 2.44985
NODAL nodal growth differentiation factor 2.44985
RLN2 relaxin 2 2.4312
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 2.41415
PTX3 pentraxin 3, long 2.41415
HEPHL1 hephaestin-like 1 2.41415
PDCD1LG2 programmed cell death 1 ligand 2 2.41026
SPMIP11 sperm microtubule inner protein 11 2.41026
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2.40995
CCDC9 coiled-coil domain containing 9 2.40995
EIF3M eukaryotic translation initiation factor 3, subunit M 2.39895
LMNTD2 lamin tail domain containing 2 2.39895
GPSM1 G-protein signaling modulator 1 2.39436
THRB thyroid hormone receptor, beta 2.37813
TMUB1 transmembrane and ubiquitin-like domain containing 1 2.37813
CDH7 cadherin 7, type 2 2.37732
TGM2 transglutaminase 2 2.35413
BET1 Bet1 golgi vesicular membrane trafficking protein 2.34007
AKR1C1 aldo-keto reductase family 1, member C1 2.28213
NOL8 nucleolar protein 8 2.22657
CDYL chromodomain protein, Y-like 2.22508
ZFPM2 zinc finger protein, FOG family member 2 2.22508
NFRKB nuclear factor related to kappaB binding protein 2.21664
CTSK cathepsin K 2.20248
DNHD1 dynein heavy chain domain 1 2.19892
CD109 CD109 molecule 2.1851
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 2.17867
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C 2.1673
PDE5A phosphodiesterase 5A, cGMP-specific 2.14474
APLF aprataxin and PNKP like factor 2.14316
FANCF Fanconi anemia, complementation group F 2.14198
TYW5 tRNA-yW synthesizing protein 5 2.13945
DAXX death-domain associated protein 2.13094
RMDN3 regulator of microtubule dynamics 3 2.13094
SCOC short coiled-coil protein 2.12662
HESX1 HESX homeobox 1 2.10872
MED31 mediator complex subunit 31 2.10872
FANCI Fanconi anemia, complementation group I 2.10267
PRKD3 protein kinase D3 2.10102
ZNF148 zinc finger protein 148 2.0958
SSPN sarcospan 2.09542
EYA4 EYA transcriptional coactivator and phosphatase 4 2.0834
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 2.0834
PIWIL2 piwi-like RNA-mediated gene silencing 2 2.0834
XKRX XK, Kell blood group complex subunit-related, X-linked 2.0834
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 2.08154
LRRC23 leucine rich repeat containing 23 2.07897
BTN3A1 butyrophilin, subfamily 3, member A1 2.07589
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 2.07393
CRYBG1 crystallin beta-gamma domain containing 1 2.07367
KCTD13 potassium channel tetramerization domain containing 13 2.07367
SH3KBP1 SH3-domain kinase binding protein 1 2.07015
SENP6 SUMO1/sentrin specific peptidase 6 2.06608
C2ORF42 chromosome 2 open reading frame 42 2.06384
CEP85 centrosomal protein 85kDa 2.05034
NAP1L5 nucleosome assembly protein 1-like 5 2.04535
PHACTR2 phosphatase and actin regulator 2 2.04535
TMEM91 transmembrane protein 91 2.04333
ZNF668 zinc finger protein 668 2.04333
TRIOBP TRIO and F-actin binding protein 2.03503
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 2.02714
DENND6A DENN/MADD domain containing 6A 2.01377
ATL2 atlastin GTPase 2 2.01295
ZNF638 zinc finger protein 638 2.00257

decreased expression

Symbol Name Standardized Value
ERMP1 endoplasmic reticulum metallopeptidase 1 -3.00015
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) -3.00015
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 -3.00015
LYSMD2 LysM, putative peptidoglycan-binding, domain containing 2 -3.00015
PABPC4L poly(A) binding protein, cytoplasmic 4-like -3.00015
GNPDA2 glucosamine-6-phosphate deaminase 2 -3.00015
EFNA5 ephrin-A5 -3.00015
CDNF cerebral dopamine neurotrophic factor -3.00015
MMP3 matrix metallopeptidase 3 -3.00015
EEF1AKMT3 EEF1A lysine methyltransferase 3 -3.00015
GRAMD1A GRAM domain containing 1A -3.00015
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) -2.89057
RPRM reprimo, TP53 dependent G2 arrest mediator candidate -2.89057
GJB5 gap junction protein, beta 5, 31.1kDa -2.89057
CCDC38 coiled-coil domain containing 38 -2.89057
ACKR3 atypical chemokine receptor 3 -2.89057
AQP1 aquaporin 1 (Colton blood group) -2.89057
PCDHB13 protocadherin beta 13 -2.89057
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 -2.89057
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -2.89057
ZNF285 zinc finger protein 285 -2.89057
OR10A2 olfactory receptor, family 10, subfamily A, member 2 -2.89057
KIF19 kinesin family member 19 -2.89057
OR6B1 olfactory receptor, family 6, subfamily B, member 1 -2.89057
AFP alpha-fetoprotein -2.89057
AZGP1 alpha-2-glycoprotein 1, zinc-binding -2.89057
KLK4 kallikrein-related peptidase 4 -2.89057
TMEM139 transmembrane protein 139 -2.89057
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 -2.89057
SFRP5 secreted frizzled-related protein 5 -2.89057
KLK5 kallikrein-related peptidase 5 -2.89057
SVOP SV2 related protein homolog (rat) -2.89057
DND1 DND microRNA-mediated repression inhibitor 1 -2.89057
H3-7 H3.7 histone (putative) -2.89057
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 -2.89057
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -2.89057
CYS1 cystin 1 -2.89057
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 -2.89057
ZAR1L zygote arrest 1-like -2.89057
DNAH12 dynein, axonemal, heavy chain 12 -2.89057
OPRK1 opioid receptor, kappa 1 -2.89057
PLN phospholamban -2.89057
TIGD3 tigger transposable element derived 3 -2.89057
ALX4 ALX homeobox 4 -2.89057
TREH trehalase (brush-border membrane glycoprotein) -2.89057
ZNF593 zinc finger protein 593 -2.81901
HGF hepatocyte growth factor (hepapoietin A; scatter factor) -2.78448
IDS iduronate 2-sulfatase -2.74474
CNN1 calponin 1, basic, smooth muscle -2.74474
PAIP2 poly(A) binding protein interacting protein 2 -2.66622
SIAE sialic acid acetylesterase -2.64964
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) -2.6107
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -2.57272
H4C11 H4 clustered histone 11 -2.51665
PTGES3L prostaglandin E synthase 3 (cytosolic)-like -2.47264
SYNGR3 synaptogyrin 3 -2.40618
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 -2.39895
MFGE8 milk fat globule-EGF factor 8 protein -2.39702
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -2.39436
SF3B3 splicing factor 3b, subunit 3, 130kDa -2.38659
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 -2.37813
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa -2.35077
RASA1 RAS p21 protein activator (GTPase activating protein) 1 -2.32942
SOX10 SRY (sex determining region Y)-box 10 -2.21778
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -2.21778
RPUSD2 RNA pseudouridylate synthase domain containing 2 -2.20248
RAI2 retinoic acid induced 2 -2.17867
HSF5 heat shock transcription factor family member 5 -2.17867
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -2.16845
DUSP6 dual specificity phosphatase 6 -2.15842
CUL7 cullin 7 -2.14142
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -2.13341
TDRKH tudor and KH domain containing -2.13094
GHITM growth hormone inducible transmembrane protein -2.12833
HSPA8 heat shock 70kDa protein 8 -2.12706
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -2.12662
CLTRN collectrin, amino acid transport regulator -2.12662
RPL22L1 ribosomal protein L22-like 1 -2.11514
C6ORF163 chromosome 6 open reading frame 163 -2.10872
HSBP1L1 heat shock factor binding protein 1-like 1 -2.10614
EIF5 eukaryotic translation initiation factor 5 -2.10102
RET ret proto-oncogene -2.10102
PDLIM7 PDZ and LIM domain 7 (enigma) -2.0958
NCKAP5L NCK-associated protein 5-like -2.08888
RCOR2 REST corepressor 2 -2.08589
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.07367
FEZF1 FEZ family zinc finger 1 -2.07367
ATP13A1 ATPase type 13A1 -2.07367
PRCD progressive rod-cone degeneration -2.07273
ELP1 elongator acetyltransferase complex subunit 1 -2.06384
LYPLA2 lysophospholipase II -2.04687
CACFD1 calcium channel flower domain containing 1 -2.04687
GPALPP1 GPALPP motifs containing 1 -2.0409
CCNF cyclin F -2.02726
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -2.02714
TPST2 tyrosylprotein sulfotransferase 2 -2.003
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 -2.00257