CXCL1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)|This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 2919)
External Link https://ncbi.nlm.nih.gov/gene/2919
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Genes

500 genes differentially expressed following the CXCL1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
RGCC regulator of cell cycle 0.0109826
SCGB2A1 secretoglobin, family 2A, member 1 0.0105402
DEFB1 defensin, beta 1 0.0104825
KRT7 keratin 7, type II 0.0104516
SFN stratifin 0.00998658
TUBB2A tubulin, beta 2A class IIa 0.00975723
S100A2 S100 calcium binding protein A2 0.00953044
KRT14 keratin 14, type I 0.0092961
TSPAN1 tetraspanin 1 0.0092608
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.0086909
KRT5 keratin 5, type II 0.00865944
KLF6 Kruppel-like factor 6 0.00864157
KRT17 keratin 17, type I 0.00857516
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.0085034
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00819335
AKAP12 A kinase (PRKA) anchor protein 12 0.0081468
CXCL8 chemokine (C-X-C motif) ligand 8 0.00801653
ASS1 argininosuccinate synthase 1 0.00787504
DHDDS dehydrodolichyl diphosphate synthase 0.00784576
WDR7 WD repeat domain 7 0.00774837
ISG20 interferon stimulated exonuclease gene 20kDa 0.00770801
CHGB chromogranin B 0.00769738
GNAS GNAS complex locus 0.00762783
ATF3 activating transcription factor 3 0.00742736
SCGB2A2 secretoglobin, family 2A, member 2 0.0073647
PODXL podocalyxin-like 0.00732827
BHLHE41 basic helix-loop-helix family, member e41 0.00730826
ABLIM1 actin binding LIM protein 1 0.0072782
TUBB6 tubulin, beta 6 class V 0.00724971
MUC16 mucin 16, cell surface associated 0.00724188
SLPI secretory leukocyte peptidase inhibitor 0.00720185
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.00717354
BIK BCL2-interacting killer (apoptosis-inducing) 0.00709766
YPEL5 yippee-like 5 (Drosophila) 0.00708329
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.00703039
TACSTD2 tumor-associated calcium signal transducer 2 0.00698209
CST1 cystatin SN 0.00697026
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00694653
GREM1 gremlin 1, DAN family BMP antagonist 0.00693858
PLAUR plasminogen activator, urokinase receptor 0.00690178
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.00685284
TRIM29 tripartite motif containing 29 0.00683343
HMOX1 heme oxygenase 1 0.00682961
KRT23 keratin 23, type I 0.00682695
PLK2 polo-like kinase 2 0.00676303
ZNF91 zinc finger protein 91 0.00670992
RGS4 regulator of G-protein signaling 4 0.00667624
PRSS21 protease, serine, 21 (testisin) 0.00664204
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00662955
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00662051
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.00655691
S100A7 S100 calcium binding protein A7 0.00654085
PEG10 paternally expressed 10 0.00635739
LAMC2 laminin, gamma 2 0.00625779
BPHL biphenyl hydrolase-like (serine hydrolase) 0.0062576
TNIP1 TNFAIP3 interacting protein 1 0.00625423
CLDN8 claudin 8 0.00624658
NVL nuclear VCP-like 0.00620792
CPM carboxypeptidase M 0.00615166
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00615085
LCN2 lipocalin 2 0.00612677
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00606188
UBE2J1 ubiquitin-conjugating enzyme E2, J1 0.00591532
CFB complement factor B 0.00588752
SLC38A1 solute carrier family 38, member 1 0.00586313
ZBED2 zinc finger, BED-type containing 2 0.00584226
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.00582426
CD52 CD52 molecule 0.00581709
COG7 component of oligomeric golgi complex 7 0.0057962
OSBPL1A oxysterol binding protein-like 1A 0.00577252
EDN3 endothelin 3 0.00575603
CLDN7 claudin 7 0.00573954
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00570821
ZNF395 zinc finger protein 395 0.00570802
DSP desmoplakin 0.00568391
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 0.00568326
RIOK3 RIO kinase 3 0.00568013
CSTA cystatin A (stefin A) 0.0056796
WFDC2 WAP four-disulfide core domain 2 0.00566342
CD79A CD79a molecule, immunoglobulin-associated alpha 0.00566215
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.00559922
LXN latexin 0.00559001
EDN1 endothelin 1 0.00556148
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00551946
CIAPIN1 cytokine induced apoptosis inhibitor 1 0.00549246
RRAGD Ras-related GTP binding D 0.00548078
SYT1 synaptotagmin I 0.00547335
SCG5 secretogranin V 0.00543492
GPX1 glutathione peroxidase 1 0.0054101
VLDLR very low density lipoprotein receptor 0.00540843
MVP major vault protein 0.00540563
IFITM3 interferon induced transmembrane protein 3 0.00538847
NEBL nebulette 0.00538269
KRT6A keratin 6A, type II 0.00537318
CRIP1 cysteine-rich protein 1 (intestinal) 0.00536515
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.00535379
ZMAT3 zinc finger, matrin-type 3 0.00535348
BTG2 BTG family, member 2 0.00535289
ADM adrenomedullin 0.00534828
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00533353
IRF6 interferon regulatory factor 6 0.00532437
TGIF1 TGFB-induced factor homeobox 1 0.00531276
MT1X metallothionein 1X 0.00529404
OPTN optineurin 0.00528812
KYNU kynureninase 0.00528296
GOLGA8A golgin A8 family, member A 0.00527882
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 0.00527539
S100A10 S100 calcium binding protein A10 0.00527172
MEIS1 Meis homeobox 1 0.0052701
EMX2 empty spiracles homeobox 2 0.00527008
PLAAT3 phospholipase A and acyltransferase 3 0.00526888
LBH limb bud and heart development 0.00524924
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.00513604
IER5 immediate early response 5 0.00513591
TM4SF1 transmembrane 4 L six family member 1 0.00513434
IL1RN interleukin 1 receptor antagonist 0.00512162
KLK6 kallikrein-related peptidase 6 0.00510809
PFKP phosphofructokinase, platelet 0.00510349
STXBP2 syntaxin binding protein 2 0.00509446
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00506872
BAMBI BMP and activin membrane-bound inhibitor 0.00506621
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.00504914
AKAP9 A kinase (PRKA) anchor protein 9 0.00504638
MYOF myoferlin 0.00503161
PNMA8A PNMA family member 8A 0.00501697
CRYAB crystallin, alpha B 0.00501002
ZYX zyxin 0.00499521
SFRP4 secreted frizzled-related protein 4 0.004966
PDE1A phosphodiesterase 1A, calmodulin-dependent 0.00495944
EMP1 epithelial membrane protein 1 0.00494977
CD200 CD200 molecule 0.00493584
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.00493184
CD14 CD14 molecule 0.00490275
MICB MHC class I polypeptide-related sequence B 0.00489879
SPRR3 small proline-rich protein 3 0.00489693
AHR aryl hydrocarbon receptor 0.00489296
MIR22HG MIR22 host gene 0.00488972
NRIP1 nuclear receptor interacting protein 1 0.00487609
IFI27 interferon, alpha-inducible protein 27 0.00484894
MCAM melanoma cell adhesion molecule 0.00484386
EGFL6 EGF-like-domain, multiple 6 0.00484194
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00483521
PLIN3 perilipin 3 0.00483319
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.00482856
ADIPOQ adiponectin, C1Q and collagen domain containing 0.00482604
TCL1A T-cell leukemia/lymphoma 1A 0.00482159
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.0048093
MMP7 matrix metallopeptidase 7 0.00480424
GBP2 guanylate binding protein 2, interferon-inducible 0.00479385
SNAP25 synaptosomal-associated protein, 25kDa 0.00477411
DDR2 discoidin domain receptor tyrosine kinase 2 0.00477203
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 0.00477087
KRT81 keratin 81, type II 0.00476753
KIAA0040 KIAA0040 0.00476096
THBS1 thrombospondin 1 0.00475677
STMN2 stathmin 2 0.00472284
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.00472093
BAG3 BCL2-associated athanogene 3 0.00471977
CLDN10 claudin 10 0.00471714
MBL2 mannose-binding lectin (protein C) 2, soluble 0.00470881
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 0.00469766
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00467968
TMPRSS4 transmembrane protease, serine 4 0.0046749
INHBA inhibin, beta A 0.00465308
TMEM243 transmembrane protein 243, mitochondrial 0.00465014
LAMA3 laminin, alpha 3 0.00462979
XIC X chromosome inactivation center 0.00462683
POU2AF1 POU class 2 associating factor 1 0.0046198
INAVA innate immunity activator 0.00461725
COBL cordon-bleu WH2 repeat protein 0.0046131
SCGB1D2 secretoglobin, family 1D, member 2 0.00461237
PDZK1IP1 PDZK1 interacting protein 1 0.00459954
ANXA1 annexin A1 0.00458909
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00458294
SHTN1 shootin 1 0.00458049
BID BH3 interacting domain death agonist 0.00457602
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00455394
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 0.00454298
OXA1L oxidase (cytochrome c) assembly 1-like 0.00454197
LMNA lamin A/C 0.00454148
JMJD1C jumonji domain containing 1C 0.00454045
CXCL13 chemokine (C-X-C motif) ligand 13 0.00453724
CCDC176 coiled-coil domain containing 176 0.00453418
CD36 CD36 molecule (thrombospondin receptor) 0.00452658
BMERB1 bMERB domain containing 1 0.00451953
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.0045079
GYPC glycophorin C (Gerbich blood group) 0.00450659
GIMAP4 GTPase, IMAP family member 4 0.00450434
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.0045039
S100A14 S100 calcium binding protein A14 0.00449905
USP18 ubiquitin specific peptidase 18 0.00449671
SPATS2L spermatogenesis associated, serine-rich 2-like 0.00448508
VCAN versican 0.00448212
NOD2 nucleotide-binding oligomerization domain containing 2 0.0044818
APOD apolipoprotein D 0.00447441
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.00447133
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00446637
RTCA RNA 3'-terminal phosphate cyclase 0.00445096
RBM48 RNA binding motif protein 48 0.00444539
LAMP3 lysosomal-associated membrane protein 3 0.00443196
DUSP2 dual specificity phosphatase 2 0.00442223
EYA2 EYA transcriptional coactivator and phosphatase 2 0.00442061
FOLR1 folate receptor 1 (adult) 0.00441313
SFRP1 secreted frizzled-related protein 1 0.00440952
FZD4 frizzled class receptor 4 0.00440269
ZNF394 zinc finger protein 394 0.00439543
CUTA cutA divalent cation tolerance homolog (E. coli) 0.00439526
GMPS guanine monphosphate synthase 0.00438518
GOLGA8H golgin A8 family, member H 0.00437534
ELMO1 engulfment and cell motility 1 0.00437327
NUAK1 NUAK family, SNF1-like kinase, 1 0.00435685
AKIRIN1 akirin 1 0.00434918
CLDN3 claudin 3 0.00434391
ETHE1 ethylmalonic encephalopathy 1 0.0043399
TACC2 transforming, acidic coiled-coil containing protein 2 0.00431646
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 0.00430956
ZNF410 zinc finger protein 410 0.0043071
GUSBP3 glucuronidase, beta pseudogene 3 0.00430537
FCMR Fc fragment of IgM receptor 0.00430428
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00429719
LETMD1 LETM1 domain containing 1 0.0042968
TUBA4A tubulin, alpha 4a 0.00429654
CCN2 cellular communication network factor 2 0.00429381
IER3 immediate early response 3 0.00429209
RRAGC Ras-related GTP binding C 0.00428416
TXNL1 thioredoxin-like 1 0.00427399
PIP prolactin-induced protein 0.00426868
PLK3 polo-like kinase 3 0.00426572
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.00425487
BLNK B-cell linker 0.0042435
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00423931
TP53I3 tumor protein p53 inducible protein 3 0.00421613
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 0.00421495
GSTK1 glutathione S-transferase kappa 1 0.00420294
HSPA1A heat shock 70kDa protein 1A 0.00419496
STC1 stanniocalcin 1 0.00418651
GLRX glutaredoxin (thioltransferase) 0.00418235
NEU1 sialidase 1 (lysosomal sialidase) 0.00417871
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.0041782
GABARAPL1 GABA(A) receptor-associated protein like 1 0.00417069
IQCK IQ motif containing K 0.00416632
SGCE sarcoglycan, epsilon 0.00416427
FBN2 fibrillin 2 0.00415541
BBC3 BCL2 binding component 3 0.00415157
DSG2 desmoglein 2 0.00414485
NARS1 asparaginyl-tRNA synthetase 1 0.00414301
GRB7 growth factor receptor-bound protein 7 0.00413825
CNTN1 contactin 1 0.00413375
TADA2A transcriptional adaptor 2A 0.00412182
ZNF430 zinc finger protein 430 0.00411923

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0146004
FGFR3 fibroblast growth factor receptor 3 -0.0121979
CENPE centromere protein E, 312kDa -0.00808229
DAPK1 death-associated protein kinase 1 -0.00801786
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00798359
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00796247
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00789183
C1R complement component 1, r subcomponent -0.00730909
ABHD6 abhydrolase domain containing 6 -0.00719125
ASCL1 achaete-scute family bHLH transcription factor 1 -0.00707473
LEPR leptin receptor -0.00706346
TNC tenascin C -0.00695086
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.00685752
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00677356
PDGFC platelet derived growth factor C -0.00671513
IGFBP5 insulin-like growth factor binding protein 5 -0.00667276
ADGRA3 adhesion G protein-coupled receptor A3 -0.00656303
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00656235
XPO7 exportin 7 -0.00652312
ANXA10 annexin A10 -0.00651057
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00650666
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.00641068
CXCL2 chemokine (C-X-C motif) ligand 2 -0.00640852
RUFY3 RUN and FYVE domain containing 3 -0.00628453
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.00626013
VCAM1 vascular cell adhesion molecule 1 -0.00618535
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00616518
ADGRG6 adhesion G protein-coupled receptor G6 -0.0061209
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 -0.00610247
CPB1 carboxypeptidase B1 (tissue) -0.0060931
CAV1 caveolin 1, caveolae protein, 22kDa -0.00609281
KIF18B kinesin family member 18B -0.00609204
BCHE butyrylcholinesterase -0.00608836
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.00608334
SDC2 syndecan 2 -0.00591174
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -0.00585482
HSPA4L heat shock 70kDa protein 4-like -0.00585432
ALOX5 arachidonate 5-lipoxygenase -0.00585213
MEIS2 Meis homeobox 2 -0.0058173
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.00571462
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.00571421
COL6A2 collagen, type VI, alpha 2 -0.00571193
PPA2 pyrophosphatase (inorganic) 2 -0.00564978
ATP10D ATPase, class V, type 10D -0.00564446
ELN elastin -0.00563903
GSTA1 glutathione S-transferase alpha 1 -0.00561886
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -0.00561873
SCRG1 stimulator of chondrogenesis 1 -0.00559713
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00558018
DEFA5 defensin, alpha 5, Paneth cell-specific -0.0055369
PLA1A phospholipase A1 member A -0.00553481
KDM5D lysine (K)-specific demethylase 5D -0.00552843
SRSF1 serine/arginine-rich splicing factor 1 -0.00542416
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -0.00541885
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00538676
TSPAN13 tetraspanin 13 -0.00538294
PRKCB protein kinase C, beta -0.00537117
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.00536577
ADIPOR2 adiponectin receptor 2 -0.00535251
ELOVL6 ELOVL fatty acid elongase 6 -0.00533155
P4HB prolyl 4-hydroxylase, beta polypeptide -0.00531396
NMU neuromedin U -0.00531181
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00529064
UBA6 ubiquitin-like modifier activating enzyme 6 -0.00525723
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -0.00524555
CDCA4 cell division cycle associated 4 -0.00524067
IGFBP1 insulin-like growth factor binding protein 1 -0.00521242
APOB apolipoprotein B -0.00518395
H2AZ1 H2A.Z variant histone 1 -0.00516327
ANKRD10 ankyrin repeat domain 10 -0.00514551
RXRA retinoid X receptor, alpha -0.00514548
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00513206
FRZB frizzled-related protein -0.00511094
TSPAN8 tetraspanin 8 -0.00510396
SNX7 sorting nexin 7 -0.00509774
CXCL3 chemokine (C-X-C motif) ligand 3 -0.00505028
OIP5 Opa interacting protein 5 -0.00504358
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -0.00501693
COL1A2 collagen, type I, alpha 2 -0.0050085
FAM13A family with sequence similarity 13, member A -0.00495722
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -0.00494505
STAB1 stabilin 1 -0.0049372
OLFM4 olfactomedin 4 -0.00492344
TPD52L1 tumor protein D52-like 1 -0.00488791
ARFIP1 ADP-ribosylation factor interacting protein 1 -0.00487853
PGC progastricsin (pepsinogen C) -0.0048594
CCNA2 cyclin A2 -0.00485084
RAPSN receptor-associated protein of the synapse -0.00481319
CD320 CD320 molecule -0.00480954
ATP10B ATPase, class V, type 10B -0.00479421
DEFA6 defensin, alpha 6, Paneth cell-specific -0.00477575
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -0.00477369
GEM GTP binding protein overexpressed in skeletal muscle -0.00476688
NEIL3 nei endonuclease VIII-like 3 (E. coli) -0.00476605
NTS neurotensin -0.00476474
DLX2 distal-less homeobox 2 -0.00474783
CA2 carbonic anhydrase II -0.00474648
NUP54 nucleoporin 54kDa -0.00474574
NECTIN3 nectin cell adhesion molecule 3 -0.00473955
GPX3 glutathione peroxidase 3 -0.00472087
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00471683
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00471654
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -0.00470503
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00468487
CPOX coproporphyrinogen oxidase -0.00466228
CTSK cathepsin K -0.00465929
PRKD3 protein kinase D3 -0.00465919
TSPAN7 tetraspanin 7 -0.0046479
PLS3 plastin 3 -0.0046103
COPS4 COP9 signalosome subunit 4 -0.00460038
ZMIZ1 zinc finger, MIZ-type containing 1 -0.00459682
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00457925
REG3A regenerating islet-derived 3 alpha -0.00455545
REG1A regenerating islet-derived 1 alpha -0.00454632
CFI complement factor I -0.00453967
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) -0.00453031
YTHDC1 YTH domain containing 1 -0.00452668
MEN1 multiple endocrine neoplasia I -0.00451558
FZD5 frizzled class receptor 5 -0.00450455
KIF20A kinesin family member 20A -0.00449195
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00446775
SELENOW selenoprotein W -0.00446698
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00446694
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00446088
NUSAP1 nucleolar and spindle associated protein 1 -0.00446041
FSTL1 follistatin-like 1 -0.00443485
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00442972
DCXR dicarbonyl/L-xylulose reductase -0.00442655
FABP1 fatty acid binding protein 1, liver -0.00442545
NDNF neuron-derived neurotrophic factor -0.00441178
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -0.0044106
LGALS4 lectin, galactoside-binding, soluble, 4 -0.0044066
EDNRB endothelin receptor type B -0.00440071
SUB1 SUB1 homolog (S. cerevisiae) -0.00436112
CLCN3 chloride channel, voltage-sensitive 3 -0.00435678
CPE carboxypeptidase E -0.00435558
SEPP1 selenoprotein P, plasma, 1 -0.0043411
BRCA1 breast cancer 1, early onset -0.00432129
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.00432104
HMGN5 high mobility group nucleosome binding domain 5 -0.00428866
FABP6 fatty acid binding protein 6, ileal -0.00428851
BMI1 BMI1 proto-oncogene, polycomb ring finger -0.00428465
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.00428275
FMO5 flavin containing monooxygenase 5 -0.00428202
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.00427632
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.00426797
MPRIP myosin phosphatase Rho interacting protein -0.00426053
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00423801
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.00423218
TFF3 trefoil factor 3 (intestinal) -0.00423128
DENND1B DENN/MADD domain containing 1B -0.00421854
PCGF3 polycomb group ring finger 3 -0.0042126
SLIT2 slit homolog 2 (Drosophila) -0.0042125
DCHS1 dachsous cadherin-related 1 -0.00420533
CCL14 chemokine (C-C motif) ligand 14 -0.00419582
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -0.00418767
GATA2 GATA binding protein 2 -0.00418609
ZDHHC17 zinc finger, DHHC-type containing 17 -0.004171
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00416119
LTBP2 latent transforming growth factor beta binding protein 2 -0.00415025
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide -0.0041419
KIAA1109 KIAA1109 -0.00412751
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00412221
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -0.0041173
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.00409949
CTSE cathepsin E -0.00409741
PARPBP PARP1 binding protein -0.00409708
DMD dystrophin -0.00409269
SDC3 syndecan 3 -0.00409255
MERTK MER proto-oncogene, tyrosine kinase -0.00408117
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.0040786
ADGRL3 adhesion G protein-coupled receptor L3 -0.00407717
DPYSL3 dihydropyrimidinase-like 3 -0.00406402
C4BPA complement component 4 binding protein, alpha -0.00406365
ATP5ME ATP synthase membrane subunit e -0.00406032
RAB28 RAB28, member RAS oncogene family -0.00405989
MED28 mediator complex subunit 28 -0.00405958
WDFY3 WD repeat and FYVE domain containing 3 -0.00405892
NEO1 neogenin 1 -0.00404769
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -0.00404586
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -0.00404243
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 -0.00403867
PLSCR4 phospholipid scramblase 4 -0.00403042
NPTX2 neuronal pentraxin II -0.00402319
CLINT1 clathrin interactor 1 -0.0040226
FCGRT Fc fragment of IgG, receptor, transporter, alpha -0.00400877
ARMT1 acidic residue methyltransferase 1 -0.00400841
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 -0.00400722
MRFAP1L1 Morf4 family associated protein 1-like 1 -0.00398997
CBR4 carbonyl reductase 4 -0.00398977
P3H2 prolyl 3-hydroxylase 2 -0.00398793
PID1 phosphotyrosine interaction domain containing 1 -0.00398471
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00397995
LAPTM4B lysosomal protein transmembrane 4 beta -0.00397992
HAMP hepcidin antimicrobial peptide -0.00397249
UBE2S ubiquitin-conjugating enzyme E2S -0.00397095
ANOS1 anosmin 1 -0.00396638
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00396145
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00395696
NBPF10 neuroblastoma breakpoint family, member 10 -0.00395466
GLS glutaminase -0.00394279
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.0039387
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -0.0039321
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -0.00392831
EML4 echinoderm microtubule associated protein like 4 -0.0039218
FADS1 fatty acid desaturase 1 -0.00392123
ORM1 orosomucoid 1 -0.00391748
PRMT2 protein arginine methyltransferase 2 -0.00390893
PRRX1 paired related homeobox 1 -0.00390861
ARHGAP11A Rho GTPase activating protein 11A -0.00390547
THAP9-AS1 THAP9 antisense RNA 1 -0.00389883
EPHA3 EPH receptor A3 -0.00389748
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 -0.00389564
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00389458
ITGAV integrin, alpha V -0.00389243
MXRA8 matrix-remodelling associated 8 -0.00388801
ENOPH1 enolase-phosphatase 1 -0.00387442
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.00386607
LRP4 low density lipoprotein receptor-related protein 4 -0.00386074
MRPL20 mitochondrial ribosomal protein L20 -0.00385754
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -0.0038548
C9ORF3 chromosome 9 open reading frame 3 -0.00385333
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00385247
PAQR3 progestin and adipoQ receptor family member III -0.00384487
AEBP1 AE binding protein 1 -0.00384087
FBXO21 F-box protein 21 -0.0038376
AGR2 anterior gradient 2 -0.00383747
IL7 interleukin 7 -0.00383699
PTTG1IP pituitary tumor-transforming 1 interacting protein -0.00383562
PON3 paraoxonase 3 -0.00383258
CNN3 calponin 3, acidic -0.00382181
GANAB glucosidase, alpha; neutral AB -0.00380802
TFF2 trefoil factor 2 -0.00380775
CALCA calcitonin-related polypeptide alpha -0.00380674
C1S complement component 1, s subcomponent -0.00379833
UBE2D3 ubiquitin-conjugating enzyme E2D 3 -0.00379265
GIPC2 GIPC PDZ domain containing family, member 2 -0.0037893
PFKL phosphofructokinase, liver -0.00378597
ATAD2 ATPase family, AAA domain containing 2 -0.00378421
ETFDH electron-transferring-flavoprotein dehydrogenase -0.00378153
MTTP microsomal triglyceride transfer protein -0.0037783
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -0.00376992
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.00376081
CCNB1 cyclin B1 -0.00375981
BEX1 brain expressed, X-linked 1 -0.00375651
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -0.00374644
MTCL1 microtubule crosslinking factor 1 -0.00374199
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.0037395
PRC1 protein regulator of cytokinesis 1 -0.0037322
PSAT1 phosphoserine aminotransferase 1 -0.0037317