CXCL10 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description chemokine (C-X-C motif) ligand 10|This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 3627)
External Link https://ncbi.nlm.nih.gov/gene/3627
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Genes

500 genes differentially expressed following the CXCL10 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
LTF lactotransferrin 0.0221293
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.0174434
BMP4 bone morphogenetic protein 4 0.0161459
RPA3 replication protein A3, 14kDa 0.0150069
METRN meteorin, glial cell differentiation regulator 0.0148413
CXCL12 chemokine (C-X-C motif) ligand 12 0.0128848
COLEC12 collectin sub-family member 12 0.0126022
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.0125272
JCHAIN joining chain of multimeric IgA and IgM 0.011997
BRCA1 breast cancer 1, early onset 0.0116125
MYBPC1 myosin binding protein C, slow type 0.0114808
FABP4 fatty acid binding protein 4, adipocyte 0.0113579
CXCL14 chemokine (C-X-C motif) ligand 14 0.0113445
ADIRF adipogenesis regulatory factor 0.011319
S100A9 S100 calcium binding protein A9 0.0111321
DCN decorin 0.0111027
RELN reelin 0.0110868
S100P S100 calcium binding protein P 0.0110819
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 0.0110357
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.0107646
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.0106818
S100A7 S100 calcium binding protein A7 0.0105882
METTL7A methyltransferase like 7A 0.0104717
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.010456
DCXR dicarbonyl/L-xylulose reductase 0.0103825
CLU clusterin 0.0102494
PDLIM3 PDZ and LIM domain 3 0.0101373
STXBP2 syntaxin binding protein 2 0.0101341
GSTO1 glutathione S-transferase omega 1 0.00998664
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00976897
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00975959
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.00974008
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00973039
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00967858
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00964721
POSTN periostin, osteoblast specific factor 0.00962176
SRGN serglycin 0.00958472
ASPN asporin 0.00950569
ZBTB18 zinc finger and BTB domain containing 18 0.00949164
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.0094511
GPM6B glycoprotein M6B 0.00917965
HMGB2 high mobility group box 2 0.00917519
SLN sarcolipin 0.00913361
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00903002
COX7B cytochrome c oxidase subunit VIIb 0.00901546
DAXX death-domain associated protein 0.00898488
EMP3 epithelial membrane protein 3 0.00892504
ICAM2 intercellular adhesion molecule 2 0.00889709
HILPDA hypoxia inducible lipid droplet-associated 0.00886824
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00884587
CFH complement factor H 0.00878675
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00875552
EVI2A ecotropic viral integration site 2A 0.00873629
C1ORF54 chromosome 1 open reading frame 54 0.00865312
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00862498
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 0.00861821
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00852699
LPAR1 lysophosphatidic acid receptor 1 0.00851233
LYPLA1 lysophospholipase I 0.00848096
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00845122
SNRPG small nuclear ribonucleoprotein polypeptide G 0.00845108
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.00843187
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00835905
PADI2 peptidyl arginine deiminase, type II 0.00833121
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.00832046
PCLAF PCNA clamp associated factor 0.00828164
DPYD dihydropyrimidine dehydrogenase 0.00824731
SMYD3 SET and MYND domain containing 3 0.00821151
CPVL carboxypeptidase, vitellogenic-like 0.00820155
FGFR3 fibroblast growth factor receptor 3 0.0081598
GABARAPL2 GABA(A) receptor-associated protein-like 2 0.00815209
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00813344
STOM stomatin 0.00813277
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.00810164
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00809944
IDE insulin-degrading enzyme 0.00805209
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.00802407
FGF1 fibroblast growth factor 1 (acidic) 0.00800338
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00799983
MT1E metallothionein 1E 0.00793158
CD52 CD52 molecule 0.00792235
KLF2 Kruppel-like factor 2 0.00788801
TEX30 testis expressed 30 0.00788252
PLPBP pyridoxal phosphate binding protein 0.00786838
SSBP2 single-stranded DNA binding protein 2 0.00786396
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 0.00782871
CRELD2 cysteine-rich with EGF-like domains 2 0.00781843
CNN3 calponin 3, acidic 0.00777799
PITX3 paired-like homeodomain 3 0.0077572
NAMPT nicotinamide phosphoribosyltransferase 0.0077186
MEF2C myocyte enhancer factor 2C 0.00770525
COMMD10 COMM domain containing 10 0.00766723
SIVA1 SIVA1, apoptosis-inducing factor 0.00765731
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.00761662
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.00761449
MAGT1 magnesium transporter 1 0.00761074
MGP matrix Gla protein 0.00755539
CSRP2 cysteine and glycine-rich protein 2 0.0075345
FXYD1 FXYD domain containing ion transport regulator 1 0.0075246
GMFG glia maturation factor, gamma 0.00748355
CLEC3B C-type lectin domain family 3, member B 0.00744545
SDC2 syndecan 2 0.00742889
CENPU centromere protein U 0.00736908
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00736002
SFRP4 secreted frizzled-related protein 4 0.00734537
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.00731534
ARHGAP15 Rho GTPase activating protein 15 0.00731501
H1-2 H1.2 linker histone, cluster member 0.00728363
ADK adenosine kinase 0.00727912
TIMP3 TIMP metallopeptidase inhibitor 3 0.00727407
FABP7 fatty acid binding protein 7, brain 0.00726759
PLP1 proteolipid protein 1 0.00725698
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.00724579
ANXA1 annexin A1 0.00722384
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 0.00721821
DMAC2L distal membrane arm assembly component 2 like 0.00719347
COQ8A coenzyme Q8A 0.00718154
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.00711102
C10ORF10 chromosome 10 open reading frame 10 0.0070913
CYB5A cytochrome b5 type A (microsomal) 0.00708471
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00704191
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.00702297
RTN2 reticulon 2 0.00700586
NDRG2 NDRG family member 2 0.0069874
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.00697221
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase 0.00696821
PLSCR4 phospholipid scramblase 4 0.00695813
DMD dystrophin 0.00693462
PNMA2 paraneoplastic Ma antigen 2 0.00691946
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa 0.00691542
ORM1 orosomucoid 1 0.00690455
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) 0.00689252
TNNT1 troponin T type 1 (skeletal, slow) 0.00689091
EFHD1 EF-hand domain family, member D1 0.00688391
PDGFRL platelet-derived growth factor receptor-like 0.00688186
TTN titin 0.00686056
LRRC17 leucine rich repeat containing 17 0.00685759
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00683908
CD48 CD48 molecule 0.00683836
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00683174
SAP30 Sin3A-associated protein, 30kDa 0.00682837
FNTA farnesyltransferase, CAAX box, alpha 0.00682193
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00679407
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.00679075
FAR2 fatty acyl CoA reductase 2 0.00678385
PMP2 peripheral myelin protein 2 0.00676845
HOPX HOP homeobox 0.0067672
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.00676239
CRIP2 cysteine-rich protein 2 0.00675239
AQP9 aquaporin 9 0.00669371
PIR pirin (iron-binding nuclear protein) 0.00666957
DPYSL2 dihydropyrimidinase-like 2 0.00664285
EAPP E2F-associated phosphoprotein 0.00664149
BTG3 BTG family, member 3 0.00662003
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.00659922
ECM2 extracellular matrix protein 2, female organ and adipocyte specific 0.00659382
FRZB frizzled-related protein 0.00659174
KCTD12 potassium channel tetramerization domain containing 12 0.00658853
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00656683
THBS1 thrombospondin 1 0.00655872
CLDN8 claudin 8 0.006548
NUTF2 nuclear transport factor 2 0.00654353
TMEM50B transmembrane protein 50B 0.00652492
HSBP1 heat shock factor binding protein 1 0.00652442
SAR1B secretion associated, Ras related GTPase 1B 0.0065143
MAT2B methionine adenosyltransferase II, beta 0.00651175
PEX2 peroxisomal biogenesis factor 2 0.0065023
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00649985
TMEM38B transmembrane protein 38B 0.00647639
HPF1 histone PARylation factor 1 0.00647333
LY86 lymphocyte antigen 86 0.00647224
CDK1 cyclin-dependent kinase 1 0.00646015
KLF9 Kruppel-like factor 9 0.0064553
CRABP1 cellular retinoic acid binding protein 1 0.00644551
RRAGD Ras-related GTP binding D 0.00644269
CDO1 cysteine dioxygenase type 1 0.00643787
S100B S100 calcium binding protein B 0.00643448
MYOT myotilin 0.00642193
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 0.00639793
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00639458
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 0.00639261
MAB21L2 mab-21-like 2 (C. elegans) 0.00638813
C7 complement component 7 0.00638339
ZNHIT1 zinc finger, HIT-type containing 1 0.00638063
APOC2 apolipoprotein C-II 0.0063783
AK4 adenylate kinase 4 0.00637804
THBS2 thrombospondin 2 0.00636697
TMEM255A transmembrane protein 255A 0.00636456
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.00636348
ACAT1 acetyl-CoA acetyltransferase 1 0.00635729
TMSB15A thymosin beta 15a 0.00633971
ATP5MF ATP synthase membrane subunit f 0.00633696
CUTC cutC copper transporter 0.00633373
GTF3A general transcription factor IIIA 0.00633299
DNASE1L3 deoxyribonuclease I-like 3 0.00632592
GLTP glycolipid transfer protein 0.00631336
COCH cochlin 0.00629965
WDR61 WD repeat domain 61 0.0062862
BTK Bruton agammaglobulinemia tyrosine kinase 0.00627655
ANXA6 annexin A6 0.00627297
IFI27 interferon, alpha-inducible protein 27 0.00626869
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.0062633
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00625749
PPIF peptidylprolyl isomerase F 0.00624547
PAK1IP1 PAK1 interacting protein 1 0.00623966
RGL1 ral guanine nucleotide dissociation stimulator-like 1 0.00623419
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.00623196
ELOB elongin B 0.00623136
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00622416
CD36 CD36 molecule (thrombospondin receptor) 0.0062177
TPST2 tyrosylprotein sulfotransferase 2 0.00621607
RPP30 ribonuclease P/MRP 30kDa subunit 0.0062112
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 0.00619508
COL3A1 collagen, type III, alpha 1 0.00619447
PLAT plasminogen activator, tissue 0.00618971
C12ORF29 chromosome 12 open reading frame 29 0.00618369
SLIRP SRA stem-loop interacting RNA binding protein 0.00617744
PLN phospholamban 0.00617439
PTTG1 pituitary tumor-transforming 1 0.00617362
IL17RB interleukin 17 receptor B 0.00616683
CALHM2 calcium homeostasis modulator 2 0.00614612
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 0.00614005
ADAM9 ADAM metallopeptidase domain 9 0.00613586
CKS2 CDC28 protein kinase regulatory subunit 2 0.00612234
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00609673
MPC1 mitochondrial pyruvate carrier 1 0.00608562
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 0.00608537
FSTL1 follistatin-like 1 0.00608326
CFD complement factor D (adipsin) 0.00608037
HIGD1A HIG1 hypoxia inducible domain family, member 1A 0.00607711
FXYD3 FXYD domain containing ion transport regulator 3 0.00606671
ELOC elongin C 0.00606593
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 0.00604736
COMMD8 COMM domain containing 8 0.00604631
MXRA8 matrix-remodelling associated 8 0.00602829
F3 coagulation factor III (thromboplastin, tissue factor) 0.00602106
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00601575
RDX radixin 0.00600664
VDAC3 voltage-dependent anion channel 3 0.00600623
MANF mesencephalic astrocyte-derived neurotrophic factor 0.00600192
PDE4DIP phosphodiesterase 4D interacting protein 0.00600137
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 0.00600001
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.00598472
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00598022
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 0.00597657
RMI1 RecQ mediated genome instability 1 0.00596921
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.00595837
DBF4 DBF4 zinc finger 0.00595795
PLK1 polo-like kinase 1 0.00595389
FAM216A family with sequence similarity 216, member A 0.00595158

decreased expression

Symbol Name Standardized Value
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0208393
XIC X chromosome inactivation center -0.0155622
MAP7 microtubule-associated protein 7 -0.0147742
OSBPL10 oxysterol binding protein-like 10 -0.0127032
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -0.0124286
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.0123771
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.0117015
CXCL11 chemokine (C-X-C motif) ligand 11 -0.0115046
GAB2 GRB2-associated binding protein 2 -0.0111611
KRT14 keratin 14, type I -0.0110022
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0106385
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.0102551
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00998332
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00989287
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00980735
PRAME preferentially expressed antigen in melanoma -0.00978367
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00968212
TRIB3 tribbles pseudokinase 3 -0.00954643
SPATA20 spermatogenesis associated 20 -0.00944797
MMP10 matrix metallopeptidase 10 -0.00934626
KCNK3 potassium channel, two pore domain subfamily K, member 3 -0.00933234
GREB1 growth regulation by estrogen in breast cancer 1 -0.00919209
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.00908312
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00908034
TFPI2 tissue factor pathway inhibitor 2 -0.00905193
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00891153
EMX2 empty spiracles homeobox 2 -0.00890466
TUG1 taurine up-regulated 1 (non-protein coding) -0.00887494
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.00884883
SIRT3 sirtuin 3 -0.00883448
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00883252
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00882016
TFF1 trefoil factor 1 -0.00875468
PCP4 Purkinje cell protein 4 -0.00868209
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.00866597
NDRG1 N-myc downstream regulated 1 -0.00860942
TPP1 tripeptidyl peptidase I -0.00858482
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.00848707
LAMB3 laminin, beta 3 -0.00840903
JAK1 Janus kinase 1 -0.00838393
PDZK1IP1 PDZK1 interacting protein 1 -0.0083253
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00831669
WT1 Wilms tumor 1 -0.00828844
ASS1 argininosuccinate synthase 1 -0.00822895
CRYBG1 crystallin beta-gamma domain containing 1 -0.00818968
TGFBI transforming growth factor, beta-induced, 68kDa -0.00818635
COL9A2 collagen, type IX, alpha 2 -0.00817536
PYGB phosphorylase, glycogen; brain -0.00814821
PRSS21 protease, serine, 21 (testisin) -0.00813322
VEGFA vascular endothelial growth factor A -0.00811071
CHGB chromogranin B -0.00807257
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00803489
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -0.00794403
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.00793156
QPCT glutaminyl-peptide cyclotransferase -0.00791611
MVP major vault protein -0.00786058
TXLNA taxilin alpha -0.00784571
PHB2 prohibitin 2 -0.00774139
STAT1 signal transducer and activator of transcription 1, 91kDa -0.00773186
RBPMS RNA binding protein with multiple splicing -0.007716
IPW imprinted in Prader-Willi syndrome (non-protein coding) -0.00765402
NEFH neurofilament, heavy polypeptide -0.00762152
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 -0.00762043
CXCL5 chemokine (C-X-C motif) ligand 5 -0.0076103
MLF2 myeloid leukemia factor 2 -0.00760585
NBPF10 neuroblastoma breakpoint family, member 10 -0.00756689
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00756548
COL4A6 collagen, type IV, alpha 6 -0.00755584
YBX3 Y box binding protein 3 -0.00754377
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 -0.00750876
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00741233
POU4F1 POU class 4 homeobox 1 -0.00733408
BCL2L2 BCL2-like 2 -0.00732848
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.00732272
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.007312
HMOX1 heme oxygenase 1 -0.00729174
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.00723365
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00722673
CX3CL1 chemokine (C-X3-C motif) ligand 1 -0.0072266
COL4A5 collagen, type IV, alpha 5 -0.00720235
RERE arginine-glutamic acid dipeptide (RE) repeats -0.00718496
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 -0.00717474
NUMA1 nuclear mitotic apparatus protein 1 -0.00715309
TRIM44 tripartite motif containing 44 -0.00713723
CEMIP2 cell migration inducing hyaluronidase 2 -0.00713227
ACADVL acyl-CoA dehydrogenase, very long chain -0.00712998
PRUNE2 prune homolog 2 (Drosophila) -0.00712334
KRT17 keratin 17, type I -0.00710222
H1-0 H1.0 linker histone -0.00709892
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked -0.00708783
ESYT1 extended synaptotagmin-like protein 1 -0.00708224
FKBP9 FK506 binding protein 9, 63 kDa -0.00706809
IGF2R insulin-like growth factor 2 receptor -0.00706609
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0070472
TENT5A terminal nucleotidyltransferase 5A -0.00703454
USP18 ubiquitin specific peptidase 18 -0.00703285
RRBP1 ribosome binding protein 1 -0.00700835
CTSZ cathepsin Z -0.00700434
CCS copper chaperone for superoxide dismutase -0.00700172
MMP7 matrix metallopeptidase 7 -0.00699068
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00697245
CTSA cathepsin A -0.00696712
ATP9A ATPase, class II, type 9A -0.00696005
COPS7A COP9 signalosome subunit 7A -0.00695438
OXA1L oxidase (cytochrome c) assembly 1-like -0.00693078
PAEP progestagen-associated endometrial protein -0.0069193
BCR breakpoint cluster region -0.00688346
INPPL1 inositol polyphosphate phosphatase-like 1 -0.00688181
TRIM28 tripartite motif containing 28 -0.00685425
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.00682628
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin -0.00681808
CPB1 carboxypeptidase B1 (tissue) -0.00680991
TBX3 T-box 3 -0.00679007
SEZ6L2 seizure related 6 homolog (mouse)-like 2 -0.00676902
GSTT1 glutathione S-transferase theta 1 -0.00675137
NPIPA1 nuclear pore complex interacting protein family, member A1 -0.00674678
KYNU kynureninase -0.00672994
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.00672457
CACNB2 calcium channel, voltage-dependent, beta 2 subunit -0.00671606
PFKP phosphofructokinase, platelet -0.00670831
MAST4 microtubule associated serine/threonine kinase family member 4 -0.00669453
MOCOS molybdenum cofactor sulfurase -0.00668915
NCOA3 nuclear receptor coactivator 3 -0.00667527
AQP3 aquaporin 3 (Gill blood group) -0.00666466
PERP PERP, TP53 apoptosis effector -0.00663645
TMEM131 transmembrane protein 131 -0.00663078
MYH9 myosin, heavy chain 9, non-muscle -0.00662124
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -0.00659653
RETREG2 reticulophagy regulator family member 2 -0.00655484
CDR2L cerebellar degeneration-related protein 2-like -0.00651752
MX1 MX dynamin-like GTPase 1 -0.00651614
GLG1 golgi glycoprotein 1 -0.00651541
LRP4 low density lipoprotein receptor-related protein 4 -0.00650241
TBL1X transducin (beta)-like 1X-linked -0.00650095
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.00650044
SLC38A1 solute carrier family 38, member 1 -0.00647763
ESR1 estrogen receptor 1 -0.0064738
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00646269
MARCHF6 membrane associated ring-CH-type finger 6 -0.00645214
EPN2 epsin 2 -0.00643181
ZNF83 zinc finger protein 83 -0.00640581
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.00637808
AMDHD2 amidohydrolase domain containing 2 -0.00635425
TRIM22 tripartite motif containing 22 -0.00634317
IFITM3 interferon induced transmembrane protein 3 -0.0063218
KRT7 keratin 7, type II -0.00631922
ETHE1 ethylmalonic encephalopathy 1 -0.00631559
NAV2 neuron navigator 2 -0.00630234
ATF4 activating transcription factor 4 -0.00630128
STX16 syntaxin 16 -0.00628496
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) -0.00627811
AP3D1 adaptor-related protein complex 3, delta 1 subunit -0.00625327
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -0.00622485
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.00622194
S100A10 S100 calcium binding protein A10 -0.00621857
PGD phosphogluconate dehydrogenase -0.00621706
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.00621468
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -0.00621207
KLK11 kallikrein-related peptidase 11 -0.00620734
HYOU1 hypoxia up-regulated 1 -0.006204
FGFR1 fibroblast growth factor receptor 1 -0.00614625
RRAGA Ras-related GTP binding A -0.00611222
BTBD3 BTB (POZ) domain containing 3 -0.00610537
CSAD cysteine sulfinic acid decarboxylase -0.00609867
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 -0.00609585
TPD52L1 tumor protein D52-like 1 -0.00609439
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -0.00607746
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00607572
TACC2 transforming, acidic coiled-coil containing protein 2 -0.00607139
TMPRSS2 transmembrane protease, serine 2 -0.0060685
TNIP1 TNFAIP3 interacting protein 1 -0.0060672
MACF1 microtubule-actin crosslinking factor 1 -0.00605316
LAMP1 lysosomal-associated membrane protein 1 -0.00605107
NPC1 Niemann-Pick disease, type C1 -0.00604937
BMP2 bone morphogenetic protein 2 -0.00604302
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.00603977
ARID1A AT rich interactive domain 1A (SWI-like) -0.00602833
ZYX zyxin -0.00602832
SIK3 SIK family kinase 3 -0.00601396
MYO6 myosin VI -0.00600808
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.00600376
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -0.00596127
CA12 carbonic anhydrase XII -0.00595992
PKP1 plakophilin 1 -0.00594047
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) -0.00593785
PVR poliovirus receptor -0.00593533
COL7A1 collagen, type VII, alpha 1 -0.00593325
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) -0.00593091
EXOC7 exocyst complex component 7 -0.00589515
KRT16 keratin 16, type I -0.00589119
IFITM1 interferon induced transmembrane protein 1 -0.00588066
MLXIP MLX interacting protein -0.00586643
MARS1 methionyl-tRNA synthetase 1 -0.00586431
STX4 syntaxin 4 -0.00585417
PXDN peroxidasin -0.00583716
FADS3 fatty acid desaturase 3 -0.00583617
ACIN1 apoptotic chromatin condensation inducer 1 -0.00583077
LGALS2 lectin, galactoside-binding, soluble, 2 -0.00582421
IRF9 interferon regulatory factor 9 -0.00580358
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.00577568
JUNB jun B proto-oncogene -0.00576716
MYO1D myosin ID -0.00573959
MCM2 minichromosome maintenance complex component 2 -0.00573916
DACH1 dachshund family transcription factor 1 -0.00573913
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -0.00573321
FZD5 frizzled class receptor 5 -0.00572326
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.0057169
PRKCSH protein kinase C substrate 80K-H -0.00571633
ARHGAP17 Rho GTPase activating protein 17 -0.00570848
TES testin LIM domain protein -0.00570534
PILRB paired immunoglobin-like type 2 receptor beta -0.00569926
P3H2 prolyl 3-hydroxylase 2 -0.0056932
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.00567931
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.00565252
IGSF3 immunoglobulin superfamily, member 3 -0.00564041
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.00563883
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -0.0056385
KLK2 kallikrein-related peptidase 2 -0.0056356
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -0.00563493
GOLGB1 golgin B1 -0.00563379
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -0.0056113
CCN3 cellular communication network factor 3 -0.00560135
GDI1 GDP dissociation inhibitor 1 -0.00559256
NPAS2 neuronal PAS domain protein 2 -0.00559139
NIT1 nitrilase 1 -0.00559105
CD7 CD7 molecule -0.00558334
GOLGA8A golgin A8 family, member A -0.00556388
SPEN spen family transcriptional repressor -0.00556376
ADGRE5 adhesion G protein-coupled receptor E5 -0.00555439
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00555386
IRS2 insulin receptor substrate 2 -0.00554676
AGRN agrin -0.00552637
STC1 stanniocalcin 1 -0.00550417
WFDC2 WAP four-disulfide core domain 2 -0.00550187
CRABP2 cellular retinoic acid binding protein 2 -0.00550049
ZNF318 zinc finger protein 318 -0.00549131
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -0.0054669
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B -0.00546468
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 -0.00546273
TMEM135 transmembrane protein 135 -0.00545682
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00544379
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A -0.00544038
ZNF638 zinc finger protein 638 -0.0054319
BCAP31 B-cell receptor-associated protein 31 -0.00543187
SMG7 SMG7 nonsense mediated mRNA decay factor -0.00543153
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.00543003
PTPRG protein tyrosine phosphatase, receptor type, G -0.00542404
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 -0.00542355
WARS1 tryptophanyl-tRNA synthetase 1 -0.0054174
DVL3 dishevelled segment polarity protein 3 -0.00541302