CXCL10 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description chemokine (C-X-C motif) ligand 10|This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 3627)
External Link http://www.ncbi.nlm.nih.gov/gene/3627
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Genes

50 interacting proteins for CXCL10 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ATF2 activating transcription factor 2
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CCR3 chemokine (C-C motif) receptor 3
CHUK conserved helix-loop-helix ubiquitous kinase
CSNK1A1 casein kinase 1, alpha 1
CXCR3 chemokine (C-X-C motif) receptor 3
DNM1 dynamin 1
DPP4 dipeptidyl-peptidase 4
DPP8 dipeptidyl-peptidase 8
E2F1 E2F transcription factor 1
E2F4 E2F transcription factor 4, p107/p130-binding
EP300 E1A binding protein p300
FKBP1A FK506 binding protein 1A, 12kDa
GRK6 G protein-coupled receptor kinase 6
H3F3A H3 histone, family 3A
HDAC3 histone deacetylase 3
HIST1H4F histone cluster 1, H4f
HIST3H3 histone cluster 3, H3
IGFBP7 insulin-like growth factor binding protein 7
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IRF3 interferon regulatory factor 3
JUN jun proto-oncogene
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K6 mitogen-activated protein kinase kinase 6
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MBD1 methyl-CpG binding domain protein 1
MBD2 methyl-CpG binding domain protein 2
MECP2 methyl CpG binding protein 2
NCOR2 nuclear receptor corepressor 2
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS3 nitric oxide synthase 3 (endothelial cell)
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCG protein kinase C, gamma
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBL2 retinoblastoma-like 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SPHK1 sphingosine kinase 1
VCAN versican