CXCL12 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description chemokine (C-X-C motif) ligand 12|This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 6387)
External Link https://ncbi.nlm.nih.gov/gene/6387
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Genes

500 genes differentially expressed following the CXCL12 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
IFI44L interferon-induced protein 44-like 0.0147651
MX1 MX dynamin-like GTPase 1 0.0138724
IFI44 interferon-induced protein 44 0.0136
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.0135049
ISG15 ISG15 ubiquitin-like modifier 0.0131498
IFI27 interferon, alpha-inducible protein 27 0.0123246
IFI6 interferon, alpha-inducible protein 6 0.0114971
BST2 bone marrow stromal cell antigen 2 0.010361
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00997201
MX2 MX dynamin-like GTPase 2 0.00990182
S100A2 S100 calcium binding protein A2 0.00969451
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.00955241
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.00945295
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0093199
CD93 CD93 molecule 0.00917915
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00898113
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00891264
GBP1 guanylate binding protein 1, interferon-inducible 0.00867988
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.0086241
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00861666
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.0083839
XPO7 exportin 7 0.008139
LAMP3 lysosomal-associated membrane protein 3 0.00798955
CCN2 cellular communication network factor 2 0.0079271
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00776922
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.00769702
GBP2 guanylate binding protein 2, interferon-inducible 0.00760587
RSAD2 radical S-adenosyl methionine domain containing 2 0.00752879
OASL 2'-5'-oligoadenylate synthetase-like 0.00743436
TRIM14 tripartite motif containing 14 0.00726653
ANOS1 anosmin 1 0.00721139
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00721039
TRIM22 tripartite motif containing 22 0.00706609
CXCL9 chemokine (C-X-C motif) ligand 9 0.00700532
ZNF185 zinc finger protein 185 (LIM domain) 0.00687383
LYZ lysozyme 0.00682313
SFTPD surfactant protein D 0.00681984
IFIH1 interferon induced with helicase C domain 1 0.00680864
SP110 SP110 nuclear body protein 0.00676787
PRSS21 protease, serine, 21 (testisin) 0.00676478
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.0067637
LAMB3 laminin, beta 3 0.00667906
CXCL10 chemokine (C-X-C motif) ligand 10 0.00664372
USP18 ubiquitin specific peptidase 18 0.0066197
LGALS13 lectin, galactoside-binding, soluble, 13 0.00659239
AQP1 aquaporin 1 (Colton blood group) 0.00655922
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00652499
SFTPC surfactant protein C 0.00648748
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00637422
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.00635742
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.00633013
STAT1 signal transducer and activator of transcription 1, 91kDa 0.00630933
IRF7 interferon regulatory factor 7 0.00630171
C9ORF3 chromosome 9 open reading frame 3 0.00622807
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.00617539
RBM34 RNA binding motif protein 34 0.00615526
KRT14 keratin 14, type I 0.00604436
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00599041
XAF1 XIAP associated factor 1 0.00596597
HSPB1 heat shock 27kDa protein 1 0.00590908
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.00582701
CCNA2 cyclin A2 0.00582136
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00582093
AMIGO2 adhesion molecule with Ig-like domain 2 0.00576931
FGG fibrinogen gamma chain 0.00575633
C7 complement component 7 0.00569135
BAG3 BCL2-associated athanogene 3 0.00567676
IFITM1 interferon induced transmembrane protein 1 0.00566606
AQP3 aquaporin 3 (Gill blood group) 0.00563395
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.00557418
FCN3 ficolin (collagen/fibrinogen domain containing) 3 0.0055665
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00554546
TM4SF1 transmembrane 4 L six family member 1 0.00553388
NEBL nebulette 0.00550706
MPZL2 myelin protein zero-like 2 0.00549614
IFI35 interferon-induced protein 35 0.00548103
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.00547695
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00547524
HOMER1 homer scaffolding protein 1 0.00543985
SAMD9 sterile alpha motif domain containing 9 0.00541931
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.0054141
CA2 carbonic anhydrase II 0.00541341
ETFB electron-transfer-flavoprotein, beta polypeptide 0.00540077
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00540031
KYNU kynureninase 0.00539235
IFRD2 interferon-related developmental regulator 2 0.00538825
NKX2-1 NK2 homeobox 1 0.00536439
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.00532675
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.00531381
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.00530857
NDNF neuron-derived neurotrophic factor 0.00530401
FBP1 fructose-1,6-bisphosphatase 1 0.00528423
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00527533
RTN1 reticulon 1 0.00526492
SFTPA2 surfactant protein A2 0.00526442
SLPI secretory leukocyte peptidase inhibitor 0.00525522
SARAF store-operated calcium entry-associated regulatory factor 0.00524164
HYAL1 hyaluronoglucosaminidase 1 0.0052377
CHD9 chromodomain helicase DNA binding protein 9 0.00523555
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00522208
SLC43A3 solute carrier family 43, member 3 0.00521846
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00520626
LY6E lymphocyte antigen 6 complex, locus E 0.00520146
FERMT1 fermitin family member 1 0.00517393
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.00516977
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.00516943
AIM2 absent in melanoma 2 0.00516178
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.00513361
CRYBG1 crystallin beta-gamma domain containing 1 0.00513227
COL4A2 collagen, type IV, alpha 2 0.00512988
OSMR oncostatin M receptor 0.00511736
SDC4 syndecan 4 0.00508731
CDCA4 cell division cycle associated 4 0.00507826
PARP12 poly (ADP-ribose) polymerase family, member 12 0.00504394
ZBED2 zinc finger, BED-type containing 2 0.00503902
CXCL13 chemokine (C-X-C motif) ligand 13 0.00503269
CXCL11 chemokine (C-X-C motif) ligand 11 0.0050315
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.005025
RNASET2 ribonuclease T2 0.00501449
GDI2 GDP dissociation inhibitor 2 0.0049767
GCH1 GTP cyclohydrolase 1 0.00495826
MGP matrix Gla protein 0.0049485
FILIP1L filamin A interacting protein 1-like 0.00493804
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 0.00493277
MSLN mesothelin 0.00492514
WFDC1 WAP four-disulfide core domain 1 0.00490855
BFAR bifunctional apoptosis regulator 0.0049024
EFNA1 ephrin-A1 0.00490041
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.00488152
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.00483259
ADGRF5 adhesion G protein-coupled receptor F5 0.00482871
MT2A metallothionein 2A 0.00482271
INHBB inhibin, beta B 0.00477458
MALL mal, T-cell differentiation protein-like 0.00476411
ITGA6 integrin, alpha 6 0.00473622
CD200 CD200 molecule 0.00473621
SIGMAR1 sigma non-opioid intracellular receptor 1 0.00473386
LMO3 LIM domain only 3 (rhombotin-like 2) 0.00470439
NFIB nuclear factor I/B 0.00469435
MT1H metallothionein 1H 0.00466159
NID1 nidogen 1 0.00465116
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00464472
TSPAN13 tetraspanin 13 0.00461934
ALCAM activated leukocyte cell adhesion molecule 0.00461167
LAGE3 L antigen family, member 3 0.00454107
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.00453397
EZR ezrin 0.0045268
PON3 paraoxonase 3 0.004517
MARCKSL1 MARCKS-like 1 0.00451388
ADGRG6 adhesion G protein-coupled receptor G6 0.00450975
KRT17 keratin 17, type I 0.00448008
GPC3 glypican 3 0.00447435
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 0.00446912
DRAM1 DNA-damage regulated autophagy modulator 1 0.00446724
DCTN4 dynactin 4 (p62) 0.00446689
LY6D lymphocyte antigen 6 complex, locus D 0.00446685
RRAD Ras-related associated with diabetes 0.00445979
WWC1 WW and C2 domain containing 1 0.00445234
CNIH4 cornichon family AMPA receptor auxiliary protein 4 0.00444639
MVP major vault protein 0.00444364
LEPROT leptin receptor overlapping transcript 0.00443344
SIK1 salt-inducible kinase 1 0.00441869
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00440831
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.00440019
MYO1C myosin IC 0.0043989
TXLNA taxilin alpha 0.00439884
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.00439045
BCAR3 breast cancer anti-estrogen resistance 3 0.00438167
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00435952
MAGED2 melanoma antigen family D2 0.00435057
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 0.00434638
NELL2 NEL-like 2 (chicken) 0.00433898
IRF9 interferon regulatory factor 9 0.00432292
DMAC2L distal membrane arm assembly component 2 like 0.00431382
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 0.00431108
VAMP8 vesicle-associated membrane protein 8 0.00431064
CAV2 caveolin 2 0.0043034
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) 0.00429975
DCHS1 dachsous cadherin-related 1 0.00429222
RNASEH2A ribonuclease H2, subunit A 0.00428576
TMEM204 transmembrane protein 204 0.0042848
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.0042835
CXCR4 chemokine (C-X-C motif) receptor 4 0.00426896
IER2 immediate early response 2 0.00426487
SCEL sciellin 0.0042641
HBB hemoglobin, beta 0.00425419
HBEGF heparin-binding EGF-like growth factor 0.00423886
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.00423858
CSRP1 cysteine and glycine-rich protein 1 0.00420471
BTN3A2 butyrophilin, subfamily 3, member A2 0.00419628
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00419328
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.00419257
CTTN cortactin 0.00419156
PBX3 pre-B-cell leukemia homeobox 3 0.00418727
EPHB2 EPH receptor B2 0.00418216
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00418163
VAMP5 vesicle-associated membrane protein 5 0.00417655
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.00417441
PNPO pyridoxamine 5'-phosphate oxidase 0.00416774
VEGFA vascular endothelial growth factor A 0.00416487
PDGFC platelet derived growth factor C 0.00416261
TGFB2 transforming growth factor, beta 2 0.00414581
IFI16 interferon, gamma-inducible protein 16 0.00413341
FZD6 frizzled class receptor 6 0.00412705
THBD thrombomodulin 0.00412651
STON1 stonin 1 0.00412019
LAMC2 laminin, gamma 2 0.00411207
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.0040888
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.00407992
PUM1 pumilio RNA-binding family member 1 0.00407626
XIC X chromosome inactivation center 0.00406139
EPHA2 EPH receptor A2 0.00405266
SDC1 syndecan 1 0.00404434
SLCO1B3 solute carrier organic anion transporter family, member 1B3 0.00403087
HOXD1 homeobox D1 0.00401393
GALT galactose-1-phosphate uridylyltransferase 0.00399973
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.00398133
GUCY2C guanylate cyclase 2C 0.00398101
APOLD1 apolipoprotein L domain containing 1 0.00397864
DSC2 desmocollin 2 0.00397193
MTF2 metal response element binding transcription factor 2 0.00397002
BGN biglycan 0.00396333
OSBPL10 oxysterol binding protein-like 10 0.00395617
SYNPO synaptopodin 0.003944
FSCN1 fascin actin-bundling protein 1 0.00393467
BCAP31 B-cell receptor-associated protein 31 0.00392567
SP100 SP100 nuclear antigen 0.00392008
DUSP9 dual specificity phosphatase 9 0.00391886
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00391483
C4BPA complement component 4 binding protein, alpha 0.0038898
IL18 interleukin 18 0.00388723
TMEM45A transmembrane protein 45A 0.00387027
NVL nuclear VCP-like 0.0038626
LBH limb bud and heart development 0.0038606
SFTPB surfactant protein B 0.00385275
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.00385133
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 0.00385022
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) 0.00383314
KRT1 keratin 1, type II 0.00383291
KLF7 Kruppel-like factor 7 (ubiquitous) 0.00382629
MT1HL1 metallothionein 1H-like 1 0.00382134
RXYLT1 ribitol xylosyltransferase 1 0.00381325
ADIRF adipogenesis regulatory factor 0.00380987
ESYT1 extended synaptotagmin-like protein 1 0.00380266
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00379753
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.00379562
CTSH cathepsin H 0.00379497
CRIP2 cysteine-rich protein 2 0.0037741
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 0.00377058
F2R coagulation factor II (thrombin) receptor 0.00376492

decreased expression

Symbol Name Standardized Value
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.0123943
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.01137
LTF lactotransferrin -0.011286
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.0104387
GPNMB glycoprotein (transmembrane) nmb -0.0101659
LPAR1 lysophosphatidic acid receptor 1 -0.0093198
MAP7 microtubule-associated protein 7 -0.00882641
BASP1 brain abundant, membrane attached signal protein 1 -0.00881838
ZIC1 Zic family member 1 -0.00876452
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00875961
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.00870521
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.00852981
TFF3 trefoil factor 3 (intestinal) -0.0084017
DEPTOR DEP domain containing MTOR-interacting protein -0.00821054
REG3A regenerating islet-derived 3 alpha -0.00785361
OLFM4 olfactomedin 4 -0.00746103
NIBAN1 niban apoptosis regulator 1 -0.00744539
SPON2 spondin 2, extracellular matrix protein -0.00722775
RRAGD Ras-related GTP binding D -0.00708334
EREG epiregulin -0.00706784
CDC20 cell division cycle 20 -0.00704651
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00688074
CLU clusterin -0.00677277
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00667522
LCN2 lipocalin 2 -0.00656648
UGP2 UDP-glucose pyrophosphorylase 2 -0.00649803
LSP1 lymphocyte-specific protein 1 -0.00631785
NAMPT nicotinamide phosphoribosyltransferase -0.00626543
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00624156
MYB v-myb avian myeloblastosis viral oncogene homolog -0.00621636
NTS neurotensin -0.00621215
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.00620571
ADA adenosine deaminase -0.00615204
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00613884
PERP PERP, TP53 apoptosis effector -0.00611147
FAM3C family with sequence similarity 3, member C -0.00606898
SRPK2 SRSF protein kinase 2 -0.00606568
DLD dihydrolipoamide dehydrogenase -0.00604837
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00601139
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.00594573
SPRY2 sprouty homolog 2 (Drosophila) -0.00582848
MMP9 matrix metallopeptidase 9 -0.00580241
SNAP25 synaptosomal-associated protein, 25kDa -0.00576598
FKBP11 FK506 binding protein 11, 19 kDa -0.00574911
STC2 stanniocalcin 2 -0.00572352
CXCL12 chemokine (C-X-C motif) ligand 12 -0.0057126
TNC tenascin C -0.00569608
NAV3 neuron navigator 3 -0.00568507
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00565892
WBP5 WW domain binding protein 5 -0.00565205
REG1A regenerating islet-derived 1 alpha -0.00564275
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) -0.00554073
FAM117A family with sequence similarity 117, member A -0.00552762
APOD apolipoprotein D -0.0055216
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00551369
BTF3P11 basic transcription factor 3 pseudogene 11 -0.00548428
PTPRD protein tyrosine phosphatase, receptor type, D -0.00547597
ARMCX1 armadillo repeat containing, X-linked 1 -0.00541103
EFHD2 EF-hand domain family, member D2 -0.00539651
HMGA1 high mobility group AT-hook 1 -0.00539628
XYLT1 xylosyltransferase I -0.00534114
PRUNE2 prune homolog 2 (Drosophila) -0.00532596
STK26 serine/threonine protein kinase 26 -0.00531058
FBN2 fibrillin 2 -0.00530429
CTSK cathepsin K -0.00530395
PCOLCE2 procollagen C-endopeptidase enhancer 2 -0.00527163
IPO13 importin 13 -0.00525289
NRN1 neuritin 1 -0.00525145
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -0.00525134
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.0052379
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00522407
DGKZ diacylglycerol kinase, zeta -0.0051869
PLP1 proteolipid protein 1 -0.00514753
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -0.00508248
HOXB2 homeobox B2 -0.0050819
MMP8 matrix metallopeptidase 8 -0.00507436
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.00506714
COBL cordon-bleu WH2 repeat protein -0.00506028
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.00505299
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 -0.00500316
COL6A1 collagen, type VI, alpha 1 -0.00498882
CLDN10 claudin 10 -0.0049807
VIM vimentin -0.00496094
GDF15 growth differentiation factor 15 -0.00495539
S100A11 S100 calcium binding protein A11 -0.0049548
TAC1 tachykinin, precursor 1 -0.00493457
STMN2 stathmin 2 -0.00493038
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00489917
KRT19 keratin 19, type I -0.0048916
EFHC2 EF-hand domain (C-terminal) containing 2 -0.0048851
GPI glucose-6-phosphate isomerase -0.00486776
PILRB paired immunoglobin-like type 2 receptor beta -0.00485462
ZNF329 zinc finger protein 329 -0.00483523
MFAP5 microfibrillar associated protein 5 -0.00482719
RTN2 reticulon 2 -0.00481506
SYT1 synaptotagmin I -0.00481376
VAV3 vav 3 guanine nucleotide exchange factor -0.00481148
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B -0.00480319
CD9 CD9 molecule -0.00476205
REG1B regenerating islet-derived 1 beta -0.00475749
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00475562
BMP4 bone morphogenetic protein 4 -0.00473807
FBXL7 F-box and leucine-rich repeat protein 7 -0.00473455
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00471468
LGALS3 lectin, galactoside-binding, soluble, 3 -0.00470711
ZSCAN18 zinc finger and SCAN domain containing 18 -0.00469677
GPRC5B G protein-coupled receptor, class C, group 5, member B -0.00467553
HOMER3 homer scaffolding protein 3 -0.00466819
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -0.00464281
HSPA2 heat shock 70kDa protein 2 -0.004605
CORO2B coronin, actin binding protein, 2B -0.00457392
FAM110B family with sequence similarity 110, member B -0.00456016
GAS1 growth arrest-specific 1 -0.00455888
MAN1C1 mannosidase, alpha, class 1C, member 1 -0.00455831
CAMP cathelicidin antimicrobial peptide -0.00454541
AKAP12 A kinase (PRKA) anchor protein 12 -0.0045426
MSMB microseminoprotein, beta- -0.00453409
HMGN5 high mobility group nucleosome binding domain 5 -0.00453252
EML3 echinoderm microtubule associated protein like 3 -0.00451502
CTSD cathepsin D -0.00450145
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog -0.00448922
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00448473
PDE4DIP phosphodiesterase 4D interacting protein -0.00447793
IGFBP6 insulin-like growth factor binding protein 6 -0.00447686
ANPEP alanyl (membrane) aminopeptidase -0.00447176
NRCAM neuronal cell adhesion molecule -0.00446421
GPM6B glycoprotein M6B -0.00445724
AOC1 amine oxidase, copper containing 1 -0.00444288
RORA RAR-related orphan receptor A -0.00443686
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -0.00443402
PEPD peptidase D -0.0044305
COLEC12 collectin sub-family member 12 -0.00442723
DMXL2 Dmx-like 2 -0.00442118
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -0.00439236
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00439228
PKD2 polycystic kidney disease 2 (autosomal dominant) -0.00439222
DEFA5 defensin, alpha 5, Paneth cell-specific -0.00439094
ATP5MF ATP synthase membrane subunit f -0.00438826
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -0.00437055
SNX7 sorting nexin 7 -0.00436755
PDGFRL platelet-derived growth factor receptor-like -0.00435989
ZNF43 zinc finger protein 43 -0.00435952
ARL4C ADP-ribosylation factor-like 4C -0.00434465
PTK2B protein tyrosine kinase 2 beta -0.00434248
ORC5 origin recognition complex, subunit 5 -0.00433827
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00433517
ANK2 ankyrin 2, neuronal -0.00432859
PRR5 proline rich 5 (renal) -0.00432134
MAP1A microtubule-associated protein 1A -0.00431855
ZNF274 zinc finger protein 274 -0.00431257
EFNB2 ephrin-B2 -0.00431247
SC5D sterol-C5-desaturase -0.00429286
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00428075
PTN pleiotrophin -0.00427844
FAM171A1 family with sequence similarity 171, member A1 -0.00427734
TPD52 tumor protein D52 -0.00427339
OSBPL1A oxysterol binding protein-like 1A -0.00427324
BPI bactericidal/permeability-increasing protein -0.00425536
H2AX H2A.X variant histone -0.0042545
COL6A2 collagen, type VI, alpha 2 -0.0042484
NME5 NME/NM23 family member 5 -0.00424302
SOD2 superoxide dismutase 2, mitochondrial -0.0042417
NDP Norrie disease (pseudoglioma) -0.00423942
TARP TCR gamma alternate reading frame protein -0.00423788
PROM1 prominin 1 -0.00423598
OAT ornithine aminotransferase -0.0042152
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.00421426
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -0.00421292
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00421097
GLUL glutamate-ammonia ligase -0.00420615
WASL Wiskott-Aldrich syndrome-like -0.00420542
JAM3 junctional adhesion molecule 3 -0.00420192
MTCL1 microtubule crosslinking factor 1 -0.00420058
HILPDA hypoxia inducible lipid droplet-associated -0.00419235
FGF9 fibroblast growth factor 9 -0.00418804
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.00418649
BCL2A1 BCL2-related protein A1 -0.00418124
GNAS GNAS complex locus -0.00418042
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.0041732
AUTS2 autism susceptibility candidate 2 -0.00416972
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00416683
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -0.00416184
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 -0.00414747
C1QTNF3 C1q and tumor necrosis factor related protein 3 -0.00414603
ATP5MJ ATP synthase membrane subunit j -0.00414537
TPM2 tropomyosin 2 (beta) -0.00414204
COPS7A COP9 signalosome subunit 7A -0.00413878
GAL galanin/GMAP prepropeptide -0.00413269
PMP22 peripheral myelin protein 22 -0.00413057
GPSM3 G-protein signaling modulator 3 -0.00412501
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa -0.00410148
NID2 nidogen 2 (osteonidogen) -0.00409817
KIAA0930 KIAA0930 -0.00409373
CRYAB crystallin, alpha B -0.00408272
IRX5 iroquois homeobox 5 -0.00407052
MGAM maltase-glucoamylase -0.00406794
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.00406065
ISYNA1 inositol-3-phosphate synthase 1 -0.00405768
AQP9 aquaporin 9 -0.00405653
BET1 Bet1 golgi vesicular membrane trafficking protein -0.00403769
FABP7 fatty acid binding protein 7, brain -0.00403364
EFHD1 EF-hand domain family, member D1 -0.00402943
TUBB4A tubulin, beta 4A class IVa -0.00402665
RNF167 ring finger protein 167 -0.00402565
SFRP1 secreted frizzled-related protein 1 -0.00400006
CYBA cytochrome b-245, alpha polypeptide -0.00398563
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -0.00398364
MPC2 mitochondrial pyruvate carrier 2 -0.00397947
REXO2 RNA exonuclease 2 -0.00397598
PHYH phytanoyl-CoA 2-hydroxylase -0.00396853
SFRP4 secreted frizzled-related protein 4 -0.00396817
ADAM9 ADAM metallopeptidase domain 9 -0.00396381
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.00395668
PAMR1 peptidase domain containing associated with muscle regeneration 1 -0.00395183
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.00394947
LTBP1 latent transforming growth factor beta binding protein 1 -0.00394919
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 -0.00392406
CAPN6 calpain 6 -0.00391257
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.0039045
BAG2 BCL2-associated athanogene 2 -0.00388822
EYA2 EYA transcriptional coactivator and phosphatase 2 -0.00388806
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00388505
C14ORF132 chromosome 14 open reading frame 132 -0.00388174
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -0.00387778
CD320 CD320 molecule -0.00387328
PADI2 peptidyl arginine deiminase, type II -0.00387259
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00386714
ARHGAP26 Rho GTPase activating protein 26 -0.00386135
EMX2 empty spiracles homeobox 2 -0.00385436
BMP7 bone morphogenetic protein 7 -0.00384449
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.0038413
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.0038236
ZNF22 zinc finger protein 22 -0.00382307
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -0.00382099
CD37 CD37 molecule -0.00381788
PLAGL1 pleiomorphic adenoma gene-like 1 -0.00380271
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.00378896
PKM pyruvate kinase, muscle -0.00378531
C1S complement component 1, s subcomponent -0.00378219
MME membrane metallo-endopeptidase -0.00377372
SALL1 spalt-like transcription factor 1 -0.00377363
GLCE glucuronic acid epimerase -0.00377241
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.00376609
S100P S100 calcium binding protein P -0.00376429
CALB1 calbindin 1, 28kDa -0.0037615
UBL3 ubiquitin-like 3 -0.00374812
OSR2 odd-skipped related transciption factor 2 -0.0037452
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.00373762
SI sucrase-isomaltase (alpha-glucosidase) -0.00373668
AK5 adenylate kinase 5 -0.00372965