| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | chemokine (C-X-C motif) ligand 5|This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. [provided by RefSeq, May 2013] (NCBI Entrez Gene Database, 6374) |
| External Link | https://ncbi.nlm.nih.gov/gene/6374 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the CXCL5 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0180181 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0124742 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0122876 |
| DENND2B | DENN domain containing 2B | 0.011896 |
| BCHE | butyrylcholinesterase | 0.0118639 |
| XPO7 | exportin 7 | 0.0115518 |
| PRF1 | perforin 1 (pore forming protein) | 0.0114447 |
| MAGEA3 | melanoma antigen family A3 | 0.011368 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.010999 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.0105436 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0104353 |
| CD8A | CD8a molecule | 0.0103167 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.0102909 |
| SFTPB | surfactant protein B | 0.0101005 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0100293 |
| SVIL | supervillin | 0.0100218 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | 0.0100189 |
| TBX3 | T-box 3 | 0.00993823 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.00957991 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00946817 |
| FASN | fatty acid synthase | 0.00939809 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00930326 |
| RPL10 | ribosomal protein L10 | 0.0092531 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.00923688 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | 0.00918431 |
| MLEC | malectin | 0.00917204 |
| EPHB2 | EPH receptor B2 | 0.00915939 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.00905903 |
| SFTPA2 | surfactant protein A2 | 0.00901686 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00894689 |
| LOC730101 | uncharacterized LOC730101 | 0.00892983 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00892023 |
| SLC38A10 | solute carrier family 38, member 10 | 0.00885393 |
| PRAME | preferentially expressed antigen in melanoma | 0.00882663 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | 0.00871166 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.0086717 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.00863365 |
| IL2RB | interleukin 2 receptor, beta | 0.00854112 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.00844245 |
| PITRM1 | pitrilysin metallopeptidase 1 | 0.00834418 |
| MEIS2 | Meis homeobox 2 | 0.00832985 |
| PRKCA | protein kinase C, alpha | 0.00830111 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00829981 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.00827505 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.00823075 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 0.00821983 |
| KLK3 | kallikrein-related peptidase 3 | 0.00821021 |
| CD2 | CD2 molecule | 0.00815557 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) | 0.00801669 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 0.00790036 |
| MLPH | melanophilin | 0.00789446 |
| TCTA | T-cell leukemia translocation altered | 0.00787354 |
| ZNF266 | zinc finger protein 266 | 0.00786353 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00782687 |
| FANCL | Fanconi anemia, complementation group L | 0.00781356 |
| PCGF2 | polycomb group ring finger 2 | 0.00778275 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00775592 |
| H2AX | H2A.X variant histone | 0.00772665 |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 | 0.00771829 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00771111 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | 0.00769773 |
| PAGE4 | P antigen family, member 4 (prostate associated) | 0.00767834 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.00767454 |
| GSTA4 | glutathione S-transferase alpha 4 | 0.00763412 |
| TYR | tyrosinase | 0.00762852 |
| SRPRA | SRP receptor subunit alpha | 0.00753753 |
| SMTN | smoothelin | 0.00752683 |
| SPATA20 | spermatogenesis associated 20 | 0.00751693 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00750552 |
| CDC20 | cell division cycle 20 | 0.00746746 |
| SPEN | spen family transcriptional repressor | 0.00746629 |
| ACP3 | acid phosphatase 3 | 0.00744535 |
| KLK2 | kallikrein-related peptidase 2 | 0.00744498 |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.00736041 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00735788 |
| GTF3C1 | general transcription factor IIIC, polypeptide 1, alpha 220kDa | 0.0073478 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.00733165 |
| RRBP1 | ribosome binding protein 1 | 0.0073071 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.00728728 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00728682 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.00725371 |
| ITK | IL2-inducible T-cell kinase | 0.00724574 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00716134 |
| FAM13A | family with sequence similarity 13, member A | 0.00713583 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 | 0.00705621 |
| PLAT | plasminogen activator, tissue | 0.00705278 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | 0.00704386 |
| PTCH1 | patched 1 | 0.007042 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00703425 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | 0.00702407 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.00702108 |
| NAV2 | neuron navigator 2 | 0.00700945 |
| NINL | ninein-like | 0.00699696 |
| ACACA | acetyl-CoA carboxylase alpha | 0.00699652 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00698081 |
| PRC1 | protein regulator of cytokinesis 1 | 0.00697553 |
| TUG1 | taurine up-regulated 1 (non-protein coding) | 0.00693124 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.00690545 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.00689502 |
| MAGEA12 | melanoma antigen family A12 | 0.00686422 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0068199 |
| BIN2 | bridging integrator 2 | 0.00679661 |
| GANAB | glucosidase, alpha; neutral AB | 0.00677704 |
| ESYT1 | extended synaptotagmin-like protein 1 | 0.00676693 |
| RNF167 | ring finger protein 167 | 0.00675834 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.00675434 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0067387 |
| COL9A2 | collagen, type IX, alpha 2 | 0.00673423 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00671874 |
| XCL1 | chemokine (C motif) ligand 1 | 0.00671508 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.00668787 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.00668765 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00666805 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.00665881 |
| ADGRA2 | adhesion G protein-coupled receptor A2 | 0.00663903 |
| ODC1 | ornithine decarboxylase 1 | 0.00663645 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | 0.00663544 |
| PRPF8 | pre-mRNA processing factor 8 | 0.00663375 |
| ABCC10 | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 | 0.00662994 |
| NEFH | neurofilament, heavy polypeptide | 0.00659723 |
| ELP1 | elongator acetyltransferase complex subunit 1 | 0.00658878 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00658815 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00656132 |
| MZF1 | myeloid zinc finger 1 | 0.00655322 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.0065355 |
| DROSHA | drosha, ribonuclease type III | 0.00650568 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.0064722 |
| UBB | ubiquitin B | 0.00644705 |
| ZNF337 | zinc finger protein 337 | 0.00643051 |
| TRIB2 | tribbles pseudokinase 2 | 0.00639058 |
| FSD1 | fibronectin type III and SPRY domain containing 1 | 0.00638549 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.00637389 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.00637088 |
| TGM2 | transglutaminase 2 | 0.00635379 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.00632861 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00632815 |
| NKG7 | natural killer cell granule protein 7 | 0.00631495 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.00630993 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.00629401 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 0.00625733 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | 0.00622629 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 | 0.00622005 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00621838 |
| FLOT1 | flotillin 1 | 0.00618881 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.00618062 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.00617837 |
| PTCD3 | pentatricopeptide repeat domain 3 | 0.00616254 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00614874 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.00614542 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.00613109 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic | 0.00611903 |
| MPDZ | multiple PDZ domain protein | 0.00610958 |
| EXOC7 | exocyst complex component 7 | 0.0060945 |
| PHB2 | prohibitin 2 | 0.00609012 |
| PGC | progastricsin (pepsinogen C) | 0.00606694 |
| GPATCH8 | G patch domain containing 8 | 0.00605355 |
| APMAP | adipocyte plasma membrane associated protein | 0.00605168 |
| NVL | nuclear VCP-like | 0.00605119 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.00604228 |
| CS | citrate synthase | 0.00603731 |
| CCDC86 | coiled-coil domain containing 86 | 0.00603496 |
| KCTD14 | potassium channel tetramerization domain containing 14 | 0.00598756 |
| NOTCH2 | notch 2 | 0.00598133 |
| VLDLR | very low density lipoprotein receptor | 0.00597677 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 0.00595202 |
| HMG20B | high mobility group 20B | 0.00594973 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.00594198 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) | 0.00593414 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00592753 |
| PRMT5 | protein arginine methyltransferase 5 | 0.00592696 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial | 0.00592039 |
| RBPMS | RNA binding protein with multiple splicing | 0.00589641 |
| NCKIPSD | NCK interacting protein with SH3 domain | 0.00589166 |
| TBCD | tubulin folding cofactor D | 0.00588567 |
| CD1D | CD1d molecule | 0.00587946 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | 0.00587555 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta | 0.00586668 |
| MRPS2 | mitochondrial ribosomal protein S2 | 0.00585752 |
| STON1 | stonin 1 | 0.00585093 |
| PPME1 | protein phosphatase methylesterase 1 | 0.00585084 |
| TYK2 | tyrosine kinase 2 | 0.00584928 |
| SNRPA | small nuclear ribonucleoprotein polypeptide A | 0.00584161 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) | 0.00583269 |
| TRMT5 | tRNA methyltransferase 5 | 0.00582448 |
| DUS1L | dihydrouridine synthase 1-like (S. cerevisiae) | 0.00580527 |
| FAM160B2 | family with sequence similarity 160, member B2 | 0.00579805 |
| SLC25A11 | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | 0.00579487 |
| TSPAN9 | tetraspanin 9 | 0.00579132 |
| CD320 | CD320 molecule | 0.00578787 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00578356 |
| TRIM28 | tripartite motif containing 28 | 0.00577189 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | 0.00577163 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.00576413 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.00575862 |
| UCKL1 | uridine-cytidine kinase 1-like 1 | 0.00575721 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.00575349 |
| PLXNA1 | plexin A1 | 0.00574257 |
| NKX2-1 | NK2 homeobox 1 | 0.00573991 |
| RAB3B | RAB3B, member RAS oncogene family | 0.00573848 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog | 0.00572981 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.00572654 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00570283 |
| TEX261 | testis expressed 261 | 0.00569251 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.00569165 |
| CDC25B | cell division cycle 25B | 0.00568944 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 0.0056561 |
| NUP85 | nucleoporin 85kDa | 0.00561021 |
| SIN3B | SIN3 transcription regulator family member B | 0.00560852 |
| PMM2 | phosphomannomutase 2 | 0.00560473 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00560386 |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.00560372 |
| RBM23 | RNA binding motif protein 23 | 0.00559696 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.00559602 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | 0.00558801 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00558236 |
| ATP6AP1 | ATPase, H+ transporting, lysosomal accessory protein 1 | 0.00558147 |
| TLK2 | tousled-like kinase 2 | 0.00557975 |
| DSP | desmoplakin | 0.00556722 |
| GLS | glutaminase | 0.00555389 |
| PRKD1 | protein kinase D1 | 0.00555095 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.00554471 |
| NISCH | nischarin | 0.00553677 |
| IL27RA | interleukin 27 receptor, alpha | 0.00552274 |
| SLC35E2B | solute carrier family 35, member E2B | 0.00552061 |
| G6PD | glucose-6-phosphate dehydrogenase | 0.00551681 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 | 0.00550703 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00549756 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00549451 |
| CRTC3 | CREB regulated transcription coactivator 3 | 0.00548215 |
| LONP1 | lon peptidase 1, mitochondrial | 0.00547406 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 0.00547386 |
| IRS2 | insulin receptor substrate 2 | 0.00546364 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | 0.00545497 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) | 0.00545407 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00544837 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | 0.0054298 |
| RANBP2 | RAN binding protein 2 | 0.00542047 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00542046 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0054175 |
| FAAP100 | FA core complex associated protein 100 | 0.00541456 |
| ARFGAP2 | ADP-ribosylation factor GTPase activating protein 2 | 0.00540581 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00540479 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | 0.00539924 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 0.00539134 |
| NBAS | neuroblastoma amplified sequence | 0.00539034 |
| POLRMT | polymerase (RNA) mitochondrial (DNA directed) | 0.00537392 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 0.0053699 |
| ABHD2 | abhydrolase domain containing 2 | 0.00536288 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.00535372 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | -0.0356598 |
| S100P | S100 calcium binding protein P | -0.0303133 |
| CA2 | carbonic anhydrase II | -0.0197475 |
| KRT23 | keratin 23, type I | -0.0166216 |
| ADIRF | adipogenesis regulatory factor | -0.0161461 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.0156329 |
| KRT19 | keratin 19, type I | -0.0149888 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0140009 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0139872 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0136915 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0134604 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.0133358 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.0133205 |
| HK2 | hexokinase 2 | -0.0130486 |
| LTF | lactotransferrin | -0.0129274 |
| AREG | amphiregulin | -0.0128074 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.0125557 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.0124723 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.0121933 |
| CLC | Charcot-Leyden crystal galectin | -0.0121558 |
| TPM4 | tropomyosin 4 | -0.0119002 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0118723 |
| BLNK | B-cell linker | -0.0118244 |
| CLU | clusterin | -0.0117379 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0116979 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.0115744 |
| TSPAN1 | tetraspanin 1 | -0.0115561 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.0114267 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0113694 |
| S100A8 | S100 calcium binding protein A8 | -0.011272 |
| CFD | complement factor D (adipsin) | -0.0111973 |
| MT1X | metallothionein 1X | -0.0110997 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.011034 |
| CLIC5 | chloride intracellular channel 5 | -0.0109649 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.010924 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0109105 |
| LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 | -0.0108201 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.0107222 |
| COX7B | cytochrome c oxidase subunit VIIb | -0.0107034 |
| METRN | meteorin, glial cell differentiation regulator | -0.0107015 |
| CCNG2 | cyclin G2 | -0.0105737 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.0105618 |
| RGCC | regulator of cell cycle | -0.0104777 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.010381 |
| CSTA | cystatin A (stefin A) | -0.0102381 |
| RBM34 | RNA binding motif protein 34 | -0.0102023 |
| EVI2A | ecotropic viral integration site 2A | -0.010171 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0101405 |
| CRYAB | crystallin, alpha B | -0.0100587 |
| PFDN4 | prefoldin subunit 4 | -0.0100264 |
| EMP1 | epithelial membrane protein 1 | -0.0100099 |
| NPTX2 | neuronal pentraxin II | -0.00999741 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00986606 |
| TMEM70 | transmembrane protein 70 | -0.00983867 |
| DCN | decorin | -0.00983388 |
| GMFG | glia maturation factor, gamma | -0.0098222 |
| MT1F | metallothionein 1F | -0.00981038 |
| S100A9 | S100 calcium binding protein A9 | -0.00977752 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.00972353 |
| XIC | X chromosome inactivation center | -0.00971962 |
| GAS1 | growth arrest-specific 1 | -0.00968968 |
| BEX4 | brain expressed, X-linked 4 | -0.0096746 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00966587 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00964369 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00961746 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00956033 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00954628 |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A | -0.00949217 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00949056 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00945852 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0093303 |
| HTRA1 | HtrA serine peptidase 1 | -0.00932475 |
| ANXA1 | annexin A1 | -0.00932002 |
| MPC1 | mitochondrial pyruvate carrier 1 | -0.00924417 |
| HOXC6 | homeobox C6 | -0.00921872 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00917391 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00916839 |
| METTL7A | methyltransferase like 7A | -0.00916176 |
| MT1M | metallothionein 1M | -0.00908558 |
| PEG3 | paternally expressed 3 | -0.00908229 |
| HSBP1 | heat shock factor binding protein 1 | -0.00908098 |
| GPM6B | glycoprotein M6B | -0.00901263 |
| RCAN1 | regulator of calcineurin 1 | -0.00899128 |
| CLDN10 | claudin 10 | -0.0089638 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.00894876 |
| MMP9 | matrix metallopeptidase 9 | -0.0089395 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.00891692 |
| RRAGD | Ras-related GTP binding D | -0.0088611 |
| DAXX | death-domain associated protein | -0.0088313 |
| RTN2 | reticulon 2 | -0.008826 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | -0.00881611 |
| DOK5 | docking protein 5 | -0.00881138 |
| SLN | sarcolipin | -0.00880566 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | -0.00880112 |
| S100A14 | S100 calcium binding protein A14 | -0.00880015 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | -0.00876217 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00871804 |
| THY1 | Thy-1 cell surface antigen | -0.00865547 |
| PROM1 | prominin 1 | -0.00865146 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00859409 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00859134 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00856211 |
| CLDN7 | claudin 7 | -0.00854149 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00853628 |
| ATF3 | activating transcription factor 3 | -0.00849004 |
| RBM47 | RNA binding motif protein 47 | -0.00846615 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00841338 |
| MAP7 | microtubule-associated protein 7 | -0.00839612 |
| MT1E | metallothionein 1E | -0.00839045 |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial | -0.00837891 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0083745 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00835464 |
| CD9 | CD9 molecule | -0.00829154 |
| ADD3 | adducin 3 (gamma) | -0.00827461 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00826008 |
| RAB9A | RAB9A, member RAS oncogene family | -0.00825892 |
| SAP30 | Sin3A-associated protein, 30kDa | -0.00824582 |
| CP | ceruloplasmin (ferroxidase) | -0.00823254 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00821473 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.008173 |
| RPS27L | ribosomal protein S27-like | -0.00817208 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | -0.0081599 |
| SPRR3 | small proline-rich protein 3 | -0.0081499 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00813968 |
| HBB | hemoglobin, beta | -0.00812958 |
| G0S2 | G0/G1 switch 2 | -0.00811482 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | -0.00807643 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00806541 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00806491 |
| TOB1 | transducer of ERBB2, 1 | -0.00806392 |
| TSPAN13 | tetraspanin 13 | -0.00806086 |
| CAMP | cathelicidin antimicrobial peptide | -0.00805387 |
| DEFB1 | defensin, beta 1 | -0.00804966 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -0.0080054 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00799161 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00796662 |
| TXNL1 | thioredoxin-like 1 | -0.00793579 |
| AUTS2 | autism susceptibility candidate 2 | -0.00793218 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0079193 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | -0.00791872 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00786547 |
| PITX3 | paired-like homeodomain 3 | -0.00786307 |
| HOMER1 | homer scaffolding protein 1 | -0.00785519 |
| FST | follistatin | -0.00784276 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00783631 |
| CD52 | CD52 molecule | -0.0077902 |
| MRPL18 | mitochondrial ribosomal protein L18 | -0.00777157 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00776705 |
| ALDOB | aldolase B, fructose-bisphosphate | -0.00776212 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.0077474 |
| H1-2 | H1.2 linker histone, cluster member | -0.00773569 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00772036 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00766663 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.00763042 |
| PLK2 | polo-like kinase 2 | -0.00761736 |
| LYZ | lysozyme | -0.00761124 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00761037 |
| SH3BGR | SH3 domain binding glutamate-rich protein | -0.00759952 |
| ZNF165 | zinc finger protein 165 | -0.00759342 |
| COMP | cartilage oligomeric matrix protein | -0.00758199 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00757911 |
| FRZB | frizzled-related protein | -0.00756815 |
| MT1H | metallothionein 1H | -0.00756577 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -0.00755585 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.0075227 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00749853 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00749694 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00745343 |
| BPI | bactericidal/permeability-increasing protein | -0.00744589 |
| MFAP5 | microfibrillar associated protein 5 | -0.0074003 |
| SST | somatostatin | -0.00738815 |
| SLIRP | SRA stem-loop interacting RNA binding protein | -0.00737598 |
| BUD31 | BUD31 homolog (S. cerevisiae) | -0.00736155 |
| TXN | thioredoxin | -0.0073526 |
| CPE | carboxypeptidase E | -0.00734228 |
| C5AR1 | complement component 5a receptor 1 | -0.00733817 |
| THBS2 | thrombospondin 2 | -0.00731154 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | -0.00727634 |
| TPRKB | TP53RK binding protein | -0.00724774 |
| ACYP2 | acylphosphatase 2, muscle type | -0.00722957 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00722237 |
| PRSS3 | protease, serine, 3 | -0.00722074 |
| TPBG | trophoblast glycoprotein | -0.00720668 |
| SLBP | stem-loop binding protein | -0.00720433 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00718496 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -0.00718448 |
| SGCE | sarcoglycan, epsilon | -0.00718022 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00717662 |
| THBS4 | thrombospondin 4 | -0.00716979 |
| CLCA4 | chloride channel accessory 4 | -0.00716449 |
| ZNF652 | zinc finger protein 652 | -0.00715957 |
| EREG | epiregulin | -0.00715427 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | -0.00715427 |
| NME5 | NME/NM23 family member 5 | -0.00714826 |
| ANXA4 | annexin A4 | -0.00711923 |
| KRT13 | keratin 13, type I | -0.00710666 |
| SSPN | sarcospan | -0.00709439 |
| RWDD1 | RWD domain containing 1 | -0.00708564 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.00705256 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00701047 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00698946 |
| TCL1A | T-cell leukemia/lymphoma 1A | -0.00698376 |
| IL17RB | interleukin 17 receptor B | -0.00697054 |
| IL1RN | interleukin 1 receptor antagonist | -0.00696815 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -0.00696605 |
| TPD52L1 | tumor protein D52-like 1 | -0.00696059 |
| TMEM47 | transmembrane protein 47 | -0.00695728 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00695105 |
| ELOB | elongin B | -0.00694622 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.00693522 |
| LY75 | lymphocyte antigen 75 | -0.00693107 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0069285 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.006913 |
| MGLL | monoglyceride lipase | -0.00691282 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 | -0.00690401 |
| TMEM243 | transmembrane protein 243, mitochondrial | -0.0069032 |
| FDX1 | ferredoxin 1 | -0.0068844 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | -0.00686982 |
| ATP5MG | ATP synthase membrane subunit g | -0.00685963 |
| CA12 | carbonic anhydrase XII | -0.00685534 |
| CCNH | cyclin H | -0.0068315 |
| MRPS33 | mitochondrial ribosomal protein S33 | -0.00681275 |
| MT1G | metallothionein 1G | -0.00681147 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00680248 |
| INAVA | innate immunity activator | -0.00678527 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.00678206 |
| STOM | stomatin | -0.00677517 |
| STXBP2 | syntaxin binding protein 2 | -0.0067721 |
| TFRC | transferrin receptor | -0.00676809 |
| FOLR1 | folate receptor 1 (adult) | -0.00676505 |
| PRODH | proline dehydrogenase (oxidase) 1 | -0.00673462 |
| RPL26L1 | ribosomal protein L26-like 1 | -0.00669433 |
| FPR1 | formyl peptide receptor 1 | -0.00669237 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0066768 |
| ATP5ME | ATP synthase membrane subunit e | -0.00665916 |
| DMAC2L | distal membrane arm assembly component 2 like | -0.00663969 |
| DCLK1 | doublecortin-like kinase 1 | -0.00663363 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | -0.00662895 |
| CLEC3B | C-type lectin domain family 3, member B | -0.0066171 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | -0.00660987 |
| CFH | complement factor H | -0.00659783 |
| PTK2B | protein tyrosine kinase 2 beta | -0.00659594 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.00658296 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00657741 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | -0.00656554 |
| ACKR3 | atypical chemokine receptor 3 | -0.00655051 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00654981 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00654535 |
| MB | myoglobin | -0.0065427 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.00653537 |
