CXCL8 Gene Set

Dataset Guide to Pharmacology Protein Ligands of Receptors
Category physical interactions
Type ligand (protein)
Description chemokine (C-X-C motif) ligand 8|The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3576)
External Link http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=3576
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Genes

2 receptors of the CXCL8 ligand (protein) from the curated Guide to Pharmacology Protein Ligands of Receptors dataset.

Symbol Name
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2