CXCL8 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description chemokine (C-X-C motif) ligand 8|The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3576)
External Link https://ncbi.nlm.nih.gov/gene/3576
Similar Terms
Downloads & Tools

Genes

499 genes differentially expressed following the CXCL8 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.0176043
ADIRF adipogenesis regulatory factor 0.0172679
TFPI2 tissue factor pathway inhibitor 2 0.0171211
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.0156946
BEX1 brain expressed, X-linked 1 0.0153017
STK10 serine/threonine kinase 10 0.0131587
IFI6 interferon, alpha-inducible protein 6 0.0131382
IFI27 interferon, alpha-inducible protein 27 0.0129711
TSPAN13 tetraspanin 13 0.0129306
TMSB15A thymosin beta 15a 0.0126644
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.012451
PLIN2 perilipin 2 0.0121217
IL13RA2 interleukin 13 receptor, alpha 2 0.0121184
CANT1 calcium activated nucleotidase 1 0.011869
BASP1 brain abundant, membrane attached signal protein 1 0.0116285
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.0115757
EGFL6 EGF-like-domain, multiple 6 0.0115199
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0114437
XIC X chromosome inactivation center 0.0113621
MGLL monoglyceride lipase 0.0111485
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.0110964
ADGRF5 adhesion G protein-coupled receptor F5 0.011041
CXCL14 chemokine (C-X-C motif) ligand 14 0.0109766
ACP5 acid phosphatase 5, tartrate resistant 0.0108751
MECOM MDS1 and EVI1 complex locus 0.0107406
SCG5 secretogranin V 0.0105007
CD36 CD36 molecule (thrombospondin receptor) 0.0104742
GNAS GNAS complex locus 0.0103866
APOLD1 apolipoprotein L domain containing 1 0.0103474
MT1M metallothionein 1M 0.0102095
RETREG1 reticulophagy regulator 1 0.0101828
PPP1R13B protein phosphatase 1, regulatory subunit 13B 0.0101377
TENT5A terminal nucleotidyltransferase 5A 0.0101164
DACH1 dachshund family transcription factor 1 0.0101143
CLEC2B C-type lectin domain family 2, member B 0.0099698
TSPAN8 tetraspanin 8 0.00994216
RGS5 regulator of G-protein signaling 5 0.00990946
ISG15 ISG15 ubiquitin-like modifier 0.00983789
IL6ST interleukin 6 signal transducer 0.00979881
ARG2 arginase 2 0.00977188
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.0097167
ADGRL4 adhesion G protein-coupled receptor L4 0.00971168
CLGN calmegin 0.00956155
BRD4 bromodomain containing 4 0.00951569
ACSL1 acyl-CoA synthetase long-chain family member 1 0.0094506
LSP1 lymphocyte-specific protein 1 0.00938166
CPB1 carboxypeptidase B1 (tissue) 0.0092478
IFI44 interferon-induced protein 44 0.0092257
CRABP2 cellular retinoic acid binding protein 2 0.00915124
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00909395
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00907699
CPM carboxypeptidase M 0.0089778
RGL1 ral guanine nucleotide dissociation stimulator-like 1 0.00895901
DYNLL1 dynein, light chain, LC8-type 1 0.00894875
CLEC3B C-type lectin domain family 3, member B 0.00892261
BRD2 bromodomain containing 2 0.00880826
LUM lumican 0.00880716
SEC61G Sec61 gamma subunit 0.0087552
NPY neuropeptide Y 0.00873392
IFI44L interferon-induced protein 44-like 0.00873235
MT1E metallothionein 1E 0.00868249
PDGFD platelet derived growth factor D 0.00865591
SMAD7 SMAD family member 7 0.00857852
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.00852338
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 0.00848143
PRDX2 peroxiredoxin 2 0.00846169
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.00840573
BST2 bone marrow stromal cell antigen 2 0.00838386
SST somatostatin 0.00836595
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.00832495
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.00824919
KLF5 Kruppel-like factor 5 (intestinal) 0.00820752
TSPYL5 TSPY-like 5 0.00820355
NPY1R neuropeptide Y receptor Y1 0.00820193
SEPHS2 selenophosphate synthetase 2 0.00816261
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.0081604
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00803301
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00802341
TM4SF1 transmembrane 4 L six family member 1 0.00800083
RIT1 Ras-like without CAAX 1 0.00796694
GIMAP6 GTPase, IMAP family member 6 0.00796615
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00796554
SV2C synaptic vesicle glycoprotein 2C 0.00794962
MMD monocyte to macrophage differentiation-associated 0.00791152
PFDN2 prefoldin subunit 2 0.00789862
ATP5ME ATP synthase membrane subunit e 0.0078862
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00787638
RPL26L1 ribosomal protein L26-like 1 0.00786246
TAC1 tachykinin, precursor 1 0.00785893
PEG3 paternally expressed 3 0.00784408
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00784296
CDC42 cell division cycle 42 0.00784283
TPBG trophoblast glycoprotein 0.00783725
CYTIP cytohesin 1 interacting protein 0.00783658
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.00782552
CCL4 chemokine (C-C motif) ligand 4 0.00772351
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.00766289
HMOX1 heme oxygenase 1 0.00765053
UPP1 uridine phosphorylase 1 0.0076385
IRF9 interferon regulatory factor 9 0.0076276
MAGED2 melanoma antigen family D2 0.00757324
BANP BTG3 associated nuclear protein 0.00756622
S100A4 S100 calcium binding protein A4 0.00755975
EXT1 exostosin glycosyltransferase 1 0.00755567
HCP5 HLA complex P5 (non-protein coding) 0.00750211
NENF neudesin neurotrophic factor 0.00749995
ZDHHC11 zinc finger, DHHC-type containing 11 0.00748969
SNAI2 snail family zinc finger 2 0.00746463
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00744123
DCLK1 doublecortin-like kinase 1 0.00743032
EIF5A eukaryotic translation initiation factor 5A 0.00741751
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.00739913
FABP4 fatty acid binding protein 4, adipocyte 0.00739839
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.00738128
PDK4 pyruvate dehydrogenase kinase, isozyme 4 0.00737281
CDH5 cadherin 5, type 2 (vascular endothelium) 0.00736768
FOSL1 FOS-like antigen 1 0.00734336
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.00728898
WASL Wiskott-Aldrich syndrome-like 0.00728802
SNX11 sorting nexin 11 0.00728587
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00728174
HLA-DRA major histocompatibility complex, class II, DR alpha 0.00728146
MAST4 microtubule associated serine/threonine kinase family member 4 0.00727877
FXYD5 FXYD domain containing ion transport regulator 5 0.0072768
AKAP12 A kinase (PRKA) anchor protein 12 0.00725662
ECM1 extracellular matrix protein 1 0.0072381
TLCD3A TLC domain containing 3A 0.0072292
RGS4 regulator of G-protein signaling 4 0.00722763
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00721006
CTSL cathepsin L 0.0072086
ABAT 4-aminobutyrate aminotransferase 0.00719807
SLC38A2 solute carrier family 38, member 2 0.00719382
PEA15 phosphoprotein enriched in astrocytes 15 0.00718762
PDCD6 programmed cell death 6 0.0071856
SPP1 secreted phosphoprotein 1 0.00717939
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00717625
RSAD2 radical S-adenosyl methionine domain containing 2 0.0071704
CTH cystathionine gamma-lyase 0.00716624
KIF5B kinesin family member 5B 0.00715722
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 0.00714698
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00712697
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00711363
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 0.00707138
KRT14 keratin 14, type I 0.00706396
DYNLRB1 dynein, light chain, roadblock-type 1 0.00705737
MX1 MX dynamin-like GTPase 1 0.00705363
C8ORF4 chromosome 8 open reading frame 4 0.00705361
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 0.00704281
ARHGAP29 Rho GTPase activating protein 29 0.00704109
GPX1 glutathione peroxidase 1 0.0070368
CLDN5 claudin 5 0.00701073
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.00699339
CTSK cathepsin K 0.00698742
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.00697628
RGS16 regulator of G-protein signaling 16 0.00696958
CAVIN2 caveolae associated protein 2 0.00696726
NUPR1 nuclear protein, transcriptional regulator, 1 0.00692013
RFTN1 raftlin, lipid raft linker 1 0.00690151
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00689328
NPC1 Niemann-Pick disease, type C1 0.00688
PGF placental growth factor 0.00685892
ELOVL5 ELOVL fatty acid elongase 5 0.00685302
CHMP4A charged multivesicular body protein 4A 0.0068159
STMN2 stathmin 2 0.00679924
GNG5 guanine nucleotide binding protein (G protein), gamma 5 0.00679879
CCL19 chemokine (C-C motif) ligand 19 0.0067891
WTAP Wilms tumor 1 associated protein 0.00673804
MAP2K1 mitogen-activated protein kinase kinase 1 0.00671953
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00670755
CSNK1A1 casein kinase 1, alpha 1 0.00669931
ADRA2A adrenoceptor alpha 2A 0.00669643
THBS4 thrombospondin 4 0.00669465
DDIT3 DNA-damage-inducible transcript 3 0.00669133
ICAM2 intercellular adhesion molecule 2 0.00667561
GPR171 G protein-coupled receptor 171 0.00664604
HAX1 HCLS1 associated protein X-1 0.00664336
ECHDC3 enoyl CoA hydratase domain containing 3 0.0066379
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.00663164
PDLIM4 PDZ and LIM domain 4 0.00662973
TWIST1 twist family bHLH transcription factor 1 0.0066239
RRAGC Ras-related GTP binding C 0.00660923
DNALI1 dynein, axonemal, light intermediate chain 1 0.00660153
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.00658151
ERGIC3 ERGIC and golgi 3 0.00657053
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 0.0065704
NSG1 neuron specific gene family member 1 0.00656243
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00653482
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.0065271
EFNA1 ephrin-A1 0.00652614
PRSS23 protease, serine, 23 0.00652482
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 0.0065245
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa 0.0065005
ARF3 ADP-ribosylation factor 3 0.00649673
PCOLCE procollagen C-endopeptidase enhancer 0.00646209
IFI30 interferon, gamma-inducible protein 30 0.006458
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.00645001
HSBP1 heat shock factor binding protein 1 0.00644966
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00643115
DDRGK1 DDRGK domain containing 1 0.00642874
PRSS8 protease, serine, 8 0.00640956
S100A13 S100 calcium binding protein A13 0.0064011
NPTX2 neuronal pentraxin II 0.00639913
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.00639457
YY1AP1 YY1 associated protein 1 0.00637807
XAF1 XIAP associated factor 1 0.00637714
MLF1 myeloid leukemia factor 1 0.00637354
KIF1A kinesin family member 1A 0.00637147
PRR7 proline rich 7 (synaptic) 0.00635369
C6ORF48 chromosome 6 open reading frame 48 0.00634093
STEAP4 STEAP family member 4 0.00633313
DUSP4 dual specificity phosphatase 4 0.00633051
PITX3 paired-like homeodomain 3 0.00632985
PON3 paraoxonase 3 0.00632917
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00630969
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00630669
LY6E lymphocyte antigen 6 complex, locus E 0.00630655
GOLT1B golgi transport 1B 0.00629114
EMC3 ER membrane protein complex subunit 3 0.00628526
NIT1 nitrilase 1 0.00625427
PPARG peroxisome proliferator-activated receptor gamma 0.00624705
C21ORF91 chromosome 21 open reading frame 91 0.0062422
CSNK1D casein kinase 1, delta 0.00623802
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.00623043
PELO pelota homolog (Drosophila) 0.0062294
CSK c-src tyrosine kinase 0.00622821
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.00620225
IFI16 interferon, gamma-inducible protein 16 0.00620024
CREM cAMP responsive element modulator 0.00619758
MIR22HG MIR22 host gene 0.00619523
AMH anti-Mullerian hormone 0.00619056
KIAA0125 KIAA0125 0.00619048
CNPY2 canopy FGF signaling regulator 2 0.00618711
MAGED1 melanoma antigen family D1 0.00618592
NEU1 sialidase 1 (lysosomal sialidase) 0.00617331
MLPH melanophilin 0.00617131
EIF6 eukaryotic translation initiation factor 6 0.00616877
MYLIP myosin regulatory light chain interacting protein 0.00616668
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 0.00614898
PNOC prepronociceptin 0.00614675
CNIH4 cornichon family AMPA receptor auxiliary protein 4 0.00614355
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.00614152
CHP1 calcineurin-like EF-hand protein 1 0.00613307
INPP1 inositol polyphosphate-1-phosphatase 0.00613032
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 0.00612704
COA3 cytochrome c oxidase assembly factor 3 0.0061255
RPS27L ribosomal protein S27-like 0.00610146
TBC1D4 TBC1 domain family, member 4 0.00608657
KIAA0040 KIAA0040 0.00608349
REC8 REC8 meiotic recombination protein 0.00608156

decreased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0198953
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.0181805
KDM5D lysine (K)-specific demethylase 5D -0.014672
S100A8 S100 calcium binding protein A8 -0.0126337
ACTG2 actin, gamma 2, smooth muscle, enteric -0.0125952
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.0124517
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.0122907
KRT23 keratin 23, type I -0.011475
ELANE elastase, neutrophil expressed -0.0112172
MMP12 matrix metallopeptidase 12 -0.0110905
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0109171
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.0108287
CXCL5 chemokine (C-X-C motif) ligand 5 -0.0106515
ADAM28 ADAM metallopeptidase domain 28 -0.0105451
LRP4 low density lipoprotein receptor-related protein 4 -0.00999707
LTBP1 latent transforming growth factor beta binding protein 1 -0.00982449
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00981178
RNH1 ribonuclease/angiogenin inhibitor 1 -0.00971691
DMD dystrophin -0.00956795
KYNU kynureninase -0.00953882
BHLHE41 basic helix-loop-helix family, member e41 -0.00947103
MMP7 matrix metallopeptidase 7 -0.00931941
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -0.00918792
CHPT1 choline phosphotransferase 1 -0.00918159
SUB1 SUB1 homolog (S. cerevisiae) -0.00910009
STK38L serine/threonine kinase 38 like -0.00906645
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00890164
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.00885057
IL2RG interleukin 2 receptor, gamma -0.00875701
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.00874818
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00870893
PADI2 peptidyl arginine deiminase, type II -0.00866061
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00865682
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 -0.0086152
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.00861116
CEMIP cell migration inducing protein, hyaluronan binding -0.00859573
KIAA0226L KIAA0226-like -0.00853504
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -0.0085157
ZNF451 zinc finger protein 451 -0.00850475
CRYBG1 crystallin beta-gamma domain containing 1 -0.00846741
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.0084559
MEIS1 Meis homeobox 1 -0.00845375
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 -0.008402
AZU1 azurocidin 1 -0.0083249
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) -0.00831824
DST dystonin -0.00829402
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.00812292
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00811076
LTF lactotransferrin -0.00805653
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00805329
SVIL supervillin -0.00803826
YBX3 Y box binding protein 3 -0.00802308
RB1 retinoblastoma 1 -0.00792897
FGFR3 fibroblast growth factor receptor 3 -0.00792256
FUBP1 far upstream element (FUSE) binding protein 1 -0.00791797
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits -0.00791569
NIBAN1 niban apoptosis regulator 1 -0.00790331
NCK1 NCK adaptor protein 1 -0.00788101
TPM2 tropomyosin 2 (beta) -0.00783834
SNCAIP synuclein, alpha interacting protein -0.00781436
MEIS2 Meis homeobox 2 -0.00781109
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 -0.00780121
WNT5A wingless-type MMTV integration site family, member 5A -0.00778167
TARBP1 TAR (HIV-1) RNA binding protein 1 -0.00776896
FOXC1 forkhead box C1 -0.00776894
GRB7 growth factor receptor-bound protein 7 -0.0077624
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -0.00775301
CNN1 calponin 1, basic, smooth muscle -0.00775022
LCN2 lipocalin 2 -0.00772589
TLK1 tousled-like kinase 1 -0.00765269
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00764965
CDK14 cyclin-dependent kinase 14 -0.00764959
CLDN10 claudin 10 -0.00757941
NQO2 NAD(P)H dehydrogenase, quinone 2 -0.00757829
PTBP2 polypyrimidine tract binding protein 2 -0.00755714
YTHDC2 YTH domain containing 2 -0.0075363
PRKCA protein kinase C, alpha -0.00751409
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.0074271
RFC3 replication factor C (activator 1) 3, 38kDa -0.007408
SPRR3 small proline-rich protein 3 -0.00737404
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.00733135
DMPK dystrophia myotonica-protein kinase -0.00728908
ABHD10 abhydrolase domain containing 10 -0.0072468
CD1B CD1b molecule -0.00722816
MYH11 myosin, heavy chain 11, smooth muscle -0.00722011
CD1E CD1e molecule -0.00716802
CSTA cystatin A (stefin A) -0.00716255
H1-10 H1.10 linker histone -0.0071258
PTCH1 patched 1 -0.0070781
EFR3A EFR3 homolog A (S. cerevisiae) -0.00707356
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00707021
RGCC regulator of cell cycle -0.0070571
COL5A2 collagen, type V, alpha 2 -0.00705695
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.00704841
DERA deoxyribose-phosphate aldolase (putative) -0.00703619
MPO myeloperoxidase -0.0070065
GPX2 glutathione peroxidase 2 -0.00699633
TNC tenascin C -0.00698602
SH3YL1 SH3 and SYLF domain containing 1 -0.00698364
FABP7 fatty acid binding protein 7, brain -0.00696466
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -0.00694064
ARHGAP32 Rho GTPase activating protein 32 -0.00692628
MAP3K7 mitogen-activated protein kinase kinase kinase 7 -0.00692587
LYZ lysozyme -0.00692452
TKTL1 transketolase-like 1 -0.00691563
FOXN3 forkhead box N3 -0.00691051
CAV2 caveolin 2 -0.00690915
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.00690243
SEPHS1 selenophosphate synthetase 1 -0.00688941
CDCA4 cell division cycle associated 4 -0.00684638
PRPF4B pre-mRNA processing factor 4B -0.00683614
PDZD8 PDZ domain containing 8 -0.00678839
ATP11B ATPase, class VI, type 11B -0.00677899
NPM3 nucleophosmin/nucleoplasmin 3 -0.00677771
GPATCH8 G patch domain containing 8 -0.00675083
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00673855
ADAM19 ADAM metallopeptidase domain 19 -0.00672651
BUB3 BUB3 mitotic checkpoint protein -0.00668415
FLNA filamin A, alpha -0.00664367
FERMT1 fermitin family member 1 -0.00662607
CLC Charcot-Leyden crystal galectin -0.00662524
DEFB1 defensin, beta 1 -0.00660714
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00660322
NPR3 natriuretic peptide receptor 3 -0.00658522
CETN2 centrin, EF-hand protein, 2 -0.00655565
SDC1 syndecan 1 -0.0065555
CUTC cutC copper transporter -0.00655546
KRT6A keratin 6A, type II -0.00653332
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -0.00652879
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.0065264
MTMR11 myotubularin related protein 11 -0.00651198
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 -0.00651163
ZFP36L2 ZFP36 ring finger protein-like 2 -0.00649753
TARDBP TAR DNA binding protein -0.00649535
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.00648216
ZNF264 zinc finger protein 264 -0.00647464
ASMTL acetylserotonin O-methyltransferase-like -0.00646582
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -0.00644086
SQLE squalene epoxidase -0.00642154
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 -0.00641186
PGAP2 post-GPI attachment to proteins 2 -0.00640848
VWA8 von Willebrand factor A domain containing 8 -0.00640046
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -0.00639789
UBE2N ubiquitin-conjugating enzyme E2N -0.00635068
NTS neurotensin -0.00633107
CLEC5A C-type lectin domain family 5, member A -0.00633011
PLN phospholamban -0.00630845
GAS1 growth arrest-specific 1 -0.0063048
KIF11 kinesin family member 11 -0.00629092
PHIP pleckstrin homology domain interacting protein -0.00628205
MZB1 marginal zone B and B1 cell-specific protein -0.00628051
ADM adrenomedullin -0.00627429
MDFIC MyoD family inhibitor domain containing -0.00626901
TMPO thymopoietin -0.00624773
AFP alpha-fetoprotein -0.00624123
S100A7 S100 calcium binding protein A7 -0.00623718
NLRP2 NLR family, pyrin domain containing 2 -0.0062352
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.00622317
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 -0.00621625
STEAP3 STEAP family member 3, metalloreductase -0.00619854
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.00619683
ELP1 elongator acetyltransferase complex subunit 1 -0.00618262
BLM Bloom syndrome, RecQ helicase-like -0.00618092
OCRL oculocerebrorenal syndrome of Lowe -0.00617443
SPIB Spi-B transcription factor (Spi-1/PU.1 related) -0.00617165
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -0.00615685
CD3E CD3e molecule, epsilon (CD3-TCR complex) -0.00615615
PRKD3 protein kinase D3 -0.00613578
CBR4 carbonyl reductase 4 -0.00613274
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -0.00612952
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 -0.00612242
ARHGAP5 Rho GTPase activating protein 5 -0.00612214
JAG1 jagged 1 -0.00611949
PTHLH parathyroid hormone-like hormone -0.00611593
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 -0.00611361
CALB1 calbindin 1, 28kDa -0.00610475
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.00609951
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -0.00609388
FGF1 fibroblast growth factor 1 (acidic) -0.00608872
PSIP1 PC4 and SFRS1 interacting protein 1 -0.00608662
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -0.00607346
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.00606475
BCAS3 breast carcinoma amplified sequence 3 -0.00605663
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00602614
ADA adenosine deaminase -0.00602359
COL15A1 collagen, type XV, alpha 1 -0.00602265
MOB1A MOB kinase activator 1A -0.00601746
GUCY2C guanylate cyclase 2C -0.0060171
TADA2A transcriptional adaptor 2A -0.00600232
CEP55 centrosomal protein 55kDa -0.00598823
ANXA1 annexin A1 -0.00596955
LPAR6 lysophosphatidic acid receptor 6 -0.00595818
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -0.00595193
LMOD1 leiomodin 1 (smooth muscle) -0.00593063
PRPF4 pre-mRNA processing factor 4 -0.00592999
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) -0.0059222
PDE4B phosphodiesterase 4B, cAMP-specific -0.00590881
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00590825
GLG1 golgi glycoprotein 1 -0.00589649
METAP2 methionyl aminopeptidase 2 -0.00589433
CBX7 chromobox homolog 7 -0.00587257
NUP37 nucleoporin 37kDa -0.00586941
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 -0.00586057
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -0.00585333
API5 apoptosis inhibitor 5 -0.00583668
NOL8 nucleolar protein 8 -0.0058326
ADD3 adducin 3 (gamma) -0.00579974
ACSL4 acyl-CoA synthetase long-chain family member 4 -0.00579634
LAD1 ladinin 1 -0.00578257
PIGB phosphatidylinositol glycan anchor biosynthesis, class B -0.00577225
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 -0.00576632
KLK10 kallikrein-related peptidase 10 -0.00575378
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.00575252
HLA-DOB major histocompatibility complex, class II, DO beta -0.00572566
NOTCH3 notch 3 -0.00572295
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00571186
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B -0.0057115
FGFBP1 fibroblast growth factor binding protein 1 -0.00569777
RFC5 replication factor C (activator 1) 5, 36.5kDa -0.00569549
SNX4 sorting nexin 4 -0.0056954
PLAU plasminogen activator, urokinase -0.00567832
ADAT1 adenosine deaminase, tRNA-specific 1 -0.00567593
LIG1 ligase I, DNA, ATP-dependent -0.00567365
PAQR3 progestin and adipoQ receptor family member III -0.00566635
C1S complement component 1, s subcomponent -0.00566439
TRAPPC2 trafficking protein particle complex 2 -0.0056621
RNASE3 ribonuclease, RNase A family, 3 -0.00566203
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) -0.00565765
OPA1 optic atrophy 1 (autosomal dominant) -0.00565589
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit -0.0056454
PNMA8A PNMA family member 8A -0.00563492
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) -0.0056243
MPHOSPH9 M-phase phosphoprotein 9 -0.00562085
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00560735
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 -0.00560209
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta -0.00559281
TMEM38B transmembrane protein 38B -0.00556646
MYO1C myosin IC -0.00556201
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -0.00555972
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -0.00555632
PDZK1 PDZ domain containing 1 -0.00555234
SIRT3 sirtuin 3 -0.00555151
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00554609
RAI14 retinoic acid induced 14 -0.00553774
ZDHHC17 zinc finger, DHHC-type containing 17 -0.00551138
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -0.00550601
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -0.00549741
KPNA3 karyopherin alpha 3 (importin alpha 4) -0.0054848
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.0054815
ZC3H13 zinc finger CCCH-type containing 13 -0.00548095