CXCR1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description chemokine (C-X-C motif) receptor 1|The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3577)
External Link https://ncbi.nlm.nih.gov/gene/3577
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Genes

500 genes differentially expressed following the CXCR1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
ZNF589 zinc finger protein 589 0.0173488
IFI27 interferon, alpha-inducible protein 27 0.0150685
RGS5 regulator of G-protein signaling 5 0.0124299
HSPA1A heat shock 70kDa protein 1A 0.0121976
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.0120583
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.0117661
MT1E metallothionein 1E 0.0108385
TM4SF1 transmembrane 4 L six family member 1 0.0105937
TSPAN8 tetraspanin 8 0.0105637
MYH11 myosin, heavy chain 11, smooth muscle 0.0105304
AKAP12 A kinase (PRKA) anchor protein 12 0.0103887
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.0103494
RFTN1 raftlin, lipid raft linker 1 0.009882
OXA1L oxidase (cytochrome c) assembly 1-like 0.00987912
PLAU plasminogen activator, urokinase 0.00979076
VNN1 vanin 1 0.00956396
SRPX sushi-repeat containing protein, X-linked 0.00944681
SGK1 serum/glucocorticoid regulated kinase 1 0.00923049
PMEPA1 prostate transmembrane protein, androgen induced 1 0.00908721
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.00903888
PCSK5 proprotein convertase subtilisin/kexin type 5 0.00899451
BCHE butyrylcholinesterase 0.00897152
MTUS1 microtubule associated tumor suppressor 1 0.00879739
CAV1 caveolin 1, caveolae protein, 22kDa 0.00879565
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.00853651
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.00850139
LRRC17 leucine rich repeat containing 17 0.00849641
MEF2C myocyte enhancer factor 2C 0.00842696
KCTD12 potassium channel tetramerization domain containing 12 0.00841381
ASPN asporin 0.00831877
MT1HL1 metallothionein 1H-like 1 0.00828945
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.00826626
MCL1 myeloid cell leukemia 1 0.00823859
NELL1 NEL-like 1 (chicken) 0.00821377
MT1G metallothionein 1G 0.00817366
PELI1 pellino E3 ubiquitin protein ligase 1 0.00816138
IFI44L interferon-induced protein 44-like 0.00810492
OGN osteoglycin 0.00809829
CXCL2 chemokine (C-X-C motif) ligand 2 0.00801618
CRP C-reactive protein, pentraxin-related 0.00801512
PRSS3 protease, serine, 3 0.00800712
OLFML2A olfactomedin-like 2A 0.00795383
MGP matrix Gla protein 0.00794491
ACP5 acid phosphatase 5, tartrate resistant 0.00793342
KLF4 Kruppel-like factor 4 (gut) 0.00790547
JPT1 Jupiter microtubule associated homolog 1 0.00789892
CHP1 calcineurin-like EF-hand protein 1 0.00786879
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00784729
TAGLN transgelin 0.00779531
DPYSL3 dihydropyrimidinase-like 3 0.00779263
FN1 fibronectin 1 0.00770157
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00767117
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00766786
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00766634
EMCN endomucin 0.00762659
PTHLH parathyroid hormone-like hormone 0.00758052
SOX4 SRY (sex determining region Y)-box 4 0.00753118
THBD thrombomodulin 0.00749463
TSPAN7 tetraspanin 7 0.00749359
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00749355
AQP1 aquaporin 1 (Colton blood group) 0.00748943
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00747348
PLAT plasminogen activator, tissue 0.00742527
GSTP1 glutathione S-transferase pi 1 0.00741134
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00738318
PLN phospholamban 0.00737897
MT1H metallothionein 1H 0.00737006
ATP10B ATPase, class V, type 10B 0.00735054
NPY1R neuropeptide Y receptor Y1 0.00731403
AREG amphiregulin 0.00730963
ADGRF5 adhesion G protein-coupled receptor F5 0.0072664
MAOA monoamine oxidase A 0.00713378
TRIM22 tripartite motif containing 22 0.00710633
THBS2 thrombospondin 2 0.00709713
CALCRL calcitonin receptor-like 0.00706455
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00704456
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.00703653
MT1F metallothionein 1F 0.00702692
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00701054
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.00695845
MALL mal, T-cell differentiation protein-like 0.00695543
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.00694074
LGALS4 lectin, galactoside-binding, soluble, 4 0.00693743
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.00683456
EDNRA endothelin receptor type A 0.00681344
NES nestin 0.00679026
ADGRL2 adhesion G protein-coupled receptor L2 0.00678044
SFRP4 secreted frizzled-related protein 4 0.00677883
MX1 MX dynamin-like GTPase 1 0.00674498
COL14A1 collagen, type XIV, alpha 1 0.00671877
ALOX15B arachidonate 15-lipoxygenase, type B 0.00670752
JAG1 jagged 1 0.00670743
HMBOX1 homeobox containing 1 0.0067047
DUOX2 dual oxidase 2 0.00669258
GRK5 G protein-coupled receptor kinase 5 0.00668824
MSN moesin 0.00667169
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00665885
PCDH9 protocadherin 9 0.00664839
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00664172
IFI44 interferon-induced protein 44 0.00661289
MT1X metallothionein 1X 0.00660033
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00659936
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.00659401
CRYBG1 crystallin beta-gamma domain containing 1 0.00659105
AQP3 aquaporin 3 (Gill blood group) 0.0065351
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00648989
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00647403
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00646289
TFPI2 tissue factor pathway inhibitor 2 0.00642504
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.00640463
SCPEP1 serine carboxypeptidase 1 0.00635956
ACTG2 actin, gamma 2, smooth muscle, enteric 0.0063588
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00634837
RUFY3 RUN and FYVE domain containing 3 0.00633354
SFRP1 secreted frizzled-related protein 1 0.0063231
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) 0.00632019
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.00630412
ZNF532 zinc finger protein 532 0.00630407
CCL21 chemokine (C-C motif) ligand 21 0.00627906
ECM1 extracellular matrix protein 1 0.00624855
MCAM melanoma cell adhesion molecule 0.00624829
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.00624311
IFI16 interferon, gamma-inducible protein 16 0.006236
KIAA0355 KIAA0355 0.00622218
ABLIM3 actin binding LIM protein family, member 3 0.00621064
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.00616421
KLK10 kallikrein-related peptidase 10 0.00615654
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.00613381
SOCS1 suppressor of cytokine signaling 1 0.00613274
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00612942
CAV2 caveolin 2 0.00612704
TFF3 trefoil factor 3 (intestinal) 0.00612335
MMRN1 multimerin 1 0.00611625
IGF1R insulin-like growth factor 1 receptor 0.00609216
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 0.00608852
RBM23 RNA binding motif protein 23 0.0060693
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 0.00605941
LAMC2 laminin, gamma 2 0.00605726
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00604927
KDR kinase insert domain receptor 0.00604524
CDH5 cadherin 5, type 2 (vascular endothelium) 0.00603175
TIMP1 TIMP metallopeptidase inhibitor 1 0.00601832
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C 0.00601324
RRAD Ras-related associated with diabetes 0.00598046
VWF von Willebrand factor 0.00597779
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00597121
GIMAP6 GTPase, IMAP family member 6 0.00596797
CFH complement factor H 0.00595245
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00594898
PRMT5 protein arginine methyltransferase 5 0.00592309
FXYD5 FXYD domain containing ion transport regulator 5 0.00591829
LDB3 LIM domain binding 3 0.00591604
NKX2-1 NK2 homeobox 1 0.00591043
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00589182
HMOX1 heme oxygenase 1 0.00584163
PMP22 peripheral myelin protein 22 0.00584148
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00583952
C8ORF4 chromosome 8 open reading frame 4 0.00580844
CNOT4 CCR4-NOT transcription complex, subunit 4 0.00578158
EDNRB endothelin receptor type B 0.00577262
SH2B3 SH2B adaptor protein 3 0.0057677
MYOZ2 myozenin 2 0.00576452
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00575579
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.00575264
PHACTR4 phosphatase and actin regulator 4 0.00574681
LUM lumican 0.00574134
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.00573426
POSTN periostin, osteoblast specific factor 0.00572091
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.00571772
NFIB nuclear factor I/B 0.00571102
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00570724
GOLM1 golgi membrane protein 1 0.00565015
DCHS1 dachsous cadherin-related 1 0.00564992
WLS wntless Wnt ligand secretion mediator 0.00564361
THSD7A thrombospondin, type I, domain containing 7A 0.00562923
CXCL11 chemokine (C-X-C motif) ligand 11 0.0056189
RAB38 RAB38, member RAS oncogene family 0.00561769
PDGFD platelet derived growth factor D 0.00561204
DUSP7 dual specificity phosphatase 7 0.005588
DNMBP dynamin binding protein 0.00556221
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00554207
FRY furry homolog (Drosophila) 0.00553802
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00553618
ZW10 zw10 kinetochore protein 0.00553419
C7 complement component 7 0.00552212
LONP2 lon peptidase 2, peroxisomal 0.0055165
TMEM255A transmembrane protein 255A 0.00551368
PI3 peptidase inhibitor 3, skin-derived 0.0055103
CNTN1 contactin 1 0.00548516
ZBTB16 zinc finger and BTB domain containing 16 0.00547392
NT5E 5'-nucleotidase, ecto (CD73) 0.00546112
DOCK4 dedicator of cytokinesis 4 0.00545309
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 0.00543429
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00543168
ZBTB35 zinc finger and BTB domain containing 35 0.00542946
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.00542266
FGD6 FYVE, RhoGEF and PH domain containing 6 0.00541856
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.00541658
RRAS2 related RAS viral (r-ras) oncogene homolog 2 0.00540253
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00539176
COL3A1 collagen, type III, alpha 1 0.00539056
RABEP2 rabaptin, RAB GTPase binding effector protein 2 0.00538692
FRMD4B FERM domain containing 4B 0.00537537
GIMAP4 GTPase, IMAP family member 4 0.00537247
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.00535677
ANKRD10 ankyrin repeat domain 10 0.00535578
CXCL6 chemokine (C-X-C motif) ligand 6 0.00535557
RNF167 ring finger protein 167 0.00533766
GINS4 GINS complex subunit 4 (Sld5 homolog) 0.00531172
CELF2 CUGBP, Elav-like family member 2 0.00530933
KLK5 kallikrein-related peptidase 5 0.0053049
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa 0.00530147
STXBP2 syntaxin binding protein 2 0.0052852
CRCT1 cysteine-rich C-terminal 1 0.00523965
PLXDC1 plexin domain containing 1 0.00523305
PRELP proline/arginine-rich end leucine-rich repeat protein 0.00522974
NDNF neuron-derived neurotrophic factor 0.00522537
LHFP lipoma HMGIC fusion partner 0.00522038
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00521062
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.00520714
FOXO1 forkhead box O1 0.0052029
FRZB frizzled-related protein 0.00517223
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 0.005166
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.00516551
GPX3 glutathione peroxidase 3 0.00516379
BICD1 bicaudal D homolog 1 (Drosophila) 0.00515466
FCN3 ficolin (collagen/fibrinogen domain containing) 3 0.00515031
TMEM100 transmembrane protein 100 0.00514787
GATA6 GATA binding protein 6 0.00514436
CXCL5 chemokine (C-X-C motif) ligand 5 0.00514147
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.00511938
NCAPD3 non-SMC condensin II complex, subunit D3 0.00508329
CDK5RAP3 CDK5 regulatory subunit associated protein 3 0.00507911
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.00505654
PTPRB protein tyrosine phosphatase, receptor type, B 0.00503366
CLDN5 claudin 5 0.00503131
CEP170 centrosomal protein 170kDa 0.00502964
ADRA2A adrenoceptor alpha 2A 0.00502504
COG5 component of oligomeric golgi complex 5 0.00501674
FABP4 fatty acid binding protein 4, adipocyte 0.00501489
MLXIP MLX interacting protein 0.00501423
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.00500752
PDE4B phosphodiesterase 4B, cAMP-specific 0.00500431
GFOD1 glucose-fructose oxidoreductase domain containing 1 0.00500149
XPO7 exportin 7 0.00499939
KCTD5 potassium channel tetramerization domain containing 5 0.00498537
EIF5A eukaryotic translation initiation factor 5A 0.00497292
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.00495137
FCRL2 Fc receptor-like 2 0.00495041
LINC00623 long intergenic non-protein coding RNA 623 0.0049465

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -0.0170246
CLU clusterin -0.015858
S100A9 S100 calcium binding protein A9 -0.0134863
LYZ lysozyme -0.0126033
KRT19 keratin 19, type I -0.0125734
DSP desmoplakin -0.0122428
DLK1 delta-like 1 homolog (Drosophila) -0.0111367
LTF lactotransferrin -0.0111057
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.0110399
RHOB ras homolog family member B -0.0110318
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.0108057
FGFR3 fibroblast growth factor receptor 3 -0.010725
ASS1 argininosuccinate synthase 1 -0.0106084
IKZF1 IKAROS family zinc finger 1 (Ikaros) -0.0104127
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.0104093
S100P S100 calcium binding protein P -0.00966242
PEG3 paternally expressed 3 -0.00957359
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.00955483
S100A12 S100 calcium binding protein A12 -0.00954861
IL2RB interleukin 2 receptor, beta -0.00950955
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -0.00946972
CST7 cystatin F (leukocystatin) -0.00943831
PROM1 prominin 1 -0.00920622
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -0.00917738
RCAN1 regulator of calcineurin 1 -0.00904973
CLDN4 claudin 4 -0.00898817
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -0.00897605
PLIN2 perilipin 2 -0.00890117
BEX1 brain expressed, X-linked 1 -0.0087566
APOA2 apolipoprotein A-II -0.00869422
H1-2 H1.2 linker histone, cluster member -0.0086073
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -0.00860018
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00856681
LOX lysyl oxidase -0.00848964
VCAM1 vascular cell adhesion molecule 1 -0.00837619
KRT23 keratin 23, type I -0.00833997
HBD hemoglobin, delta -0.00822235
MNDA myeloid cell nuclear differentiation antigen -0.00802462
ANPEP alanyl (membrane) aminopeptidase -0.008
CLDN10 claudin 10 -0.00798694
NQO2 NAD(P)H dehydrogenase, quinone 2 -0.00796371
CCDC85B coiled-coil domain containing 85B -0.0078378
DHDDS dehydrodolichyl diphosphate synthase -0.00783409
FBN2 fibrillin 2 -0.00782207
AHSG alpha-2-HS-glycoprotein -0.00769426
PSG5 pregnancy specific beta-1-glycoprotein 5 -0.00764827
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.00755068
SIRT3 sirtuin 3 -0.00752419
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00747748
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00741509
QPCT glutaminyl-peptide cyclotransferase -0.0072631
CHKB choline kinase beta -0.00717424
LCN2 lipocalin 2 -0.00712269
TPM4 tropomyosin 4 -0.00699189
PCP4 Purkinje cell protein 4 -0.00696229
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00695409
OBSL1 obscurin-like 1 -0.00692975
AFP alpha-fetoprotein -0.00692017
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -0.00687641
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00682599
F3 coagulation factor III (thromboplastin, tissue factor) -0.00680852
PLPP3 phospholipid phosphatase 3 -0.00680581
TSPAN6 tetraspanin 6 -0.00678398
PRUNE2 prune homolog 2 (Drosophila) -0.00677714
NPTX2 neuronal pentraxin II -0.00674129
HSDL2 hydroxysteroid dehydrogenase like 2 -0.00673874
CRISP3 cysteine-rich secretory protein 3 -0.00673535
TTC38 tetratricopeptide repeat domain 38 -0.00672248
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00658066
MDK midkine (neurite growth-promoting factor 2) -0.00656994
PTGES prostaglandin E synthase -0.00656926
FTH1 ferritin, heavy polypeptide 1 -0.00656364
PERP PERP, TP53 apoptosis effector -0.00652373
KIF2C kinesin family member 2C -0.00648505
EMX2 empty spiracles homeobox 2 -0.00646564
MMP9 matrix metallopeptidase 9 -0.00643713
F13A1 coagulation factor XIII, A1 polypeptide -0.00641481
SPON1 spondin 1, extracellular matrix protein -0.00639582
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) -0.00639512
DCK deoxycytidine kinase -0.00637749
CHMP4A charged multivesicular body protein 4A -0.00635562
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00634931
KAZN kazrin, periplakin interacting protein -0.00634546
FKBP11 FK506 binding protein 11, 19 kDa -0.00632109
SMC1A structural maintenance of chromosomes 1A -0.006292
CCL5 chemokine (C-C motif) ligand 5 -0.00628117
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -0.00625613
EYA2 EYA transcriptional coactivator and phosphatase 2 -0.00625121
PRF1 perforin 1 (pore forming protein) -0.00624525
VAMP8 vesicle-associated membrane protein 8 -0.00622733
AMBP alpha-1-microglobulin/bikunin precursor -0.00621988
CPVL carboxypeptidase, vitellogenic-like -0.00621601
SEPTIN10 septin 10 -0.00619399
XYLT1 xylosyltransferase I -0.00619132
JUND jun D proto-oncogene -0.00618059
GPX4 glutathione peroxidase 4 -0.00615739
AIF1 allograft inflammatory factor 1 -0.00615686
DEFA4 defensin, alpha 4, corticostatin -0.00615632
UBL3 ubiquitin-like 3 -0.00613138
SHTN1 shootin 1 -0.00611502
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.00610209
RETREG2 reticulophagy regulator family member 2 -0.00605909
NFE2 nuclear factor, erythroid 2 -0.00605541
TRIB2 tribbles pseudokinase 2 -0.00601625
FBXO2 F-box protein 2 -0.00600954
HBB hemoglobin, beta -0.00597898
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00596235
GAMT guanidinoacetate N-methyltransferase -0.00595894
SDC2 syndecan 2 -0.0059562
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 -0.00593921
APOA1 apolipoprotein A-I -0.00593048
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00591358
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.00591134
MACROH2A2 macroH2A.2 histone -0.00586456
CSTA cystatin A (stefin A) -0.00586429
HPGDS hematopoietic prostaglandin D synthase -0.00584512
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -0.00583084
HOXB2 homeobox B2 -0.0058286
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) -0.00582802
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) -0.0058145
CPA3 carboxypeptidase A3 (mast cell) -0.00580607
DUSP2 dual specificity phosphatase 2 -0.00579897
PLEK pleckstrin -0.00578695
ALB albumin -0.0057684
TLE2 transducin-like enhancer of split 2 -0.00576468
ELN elastin -0.00576332
DEAF1 DEAF1 transcription factor -0.00575839
LCK LCK proto-oncogene, Src family tyrosine kinase -0.00574708
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00573377
MPP1 membrane protein, palmitoylated 1, 55kDa -0.00573225
MMP13 matrix metallopeptidase 13 -0.00569647
HNMT histamine N-methyltransferase -0.00568092
PF4 platelet factor 4 -0.00566589
LTBP1 latent transforming growth factor beta binding protein 1 -0.00566309
ATP13A3 ATPase type 13A3 -0.00565654
SUB1 SUB1 homolog (S. cerevisiae) -0.00565322
CEMIP cell migration inducing protein, hyaluronan binding -0.0056527
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.00562787
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 -0.00561701
ETFA electron-transfer-flavoprotein, alpha polypeptide -0.00559023
POR P450 (cytochrome) oxidoreductase -0.00556414
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00554603
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -0.00553551
PRODH proline dehydrogenase (oxidase) 1 -0.00553507
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.00551292
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00551227
KRT7 keratin 7, type II -0.00549751
PENK proenkephalin -0.00546646
PALM paralemmin -0.0054623
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 -0.00545796
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) -0.00545592
SDC1 syndecan 1 -0.00544987
CBS cystathionine-beta-synthase -0.00544193
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.00543868
TMPRSS4 transmembrane protease, serine 4 -0.00543685
TGFBI transforming growth factor, beta-induced, 68kDa -0.00541426
YPEL5 yippee-like 5 (Drosophila) -0.00539851
COMP cartilage oligomeric matrix protein -0.00538457
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00537794
ALAS2 5'-aminolevulinate synthase 2 -0.00536403
CDK14 cyclin-dependent kinase 14 -0.00532537
SAC3D1 SAC3 domain containing 1 -0.00531723
ACAA2 acetyl-CoA acyltransferase 2 -0.00527982
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) -0.00526833
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.00526056
ZNF331 zinc finger protein 331 -0.00525381
TYROBP TYRO protein tyrosine kinase binding protein -0.00524995
MUC16 mucin 16, cell surface associated -0.00524987
HAS2 hyaluronan synthase 2 -0.00524527
ZIC1 Zic family member 1 -0.00524174
HP haptoglobin -0.00523953
SIPA1L1 signal-induced proliferation-associated 1 like 1 -0.00521207
CHPF chondroitin polymerizing factor -0.00520882
NR1D2 nuclear receptor subfamily 1, group D, member 2 -0.00520418
ZBED1 zinc finger, BED-type containing 1 -0.00519448
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.005188
CGA glycoprotein hormones, alpha polypeptide -0.0051644
TNS3 tensin 3 -0.00516136
YEATS4 YEATS domain containing 4 -0.00515792
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B -0.00515744
ENOPH1 enolase-phosphatase 1 -0.00515568
HBQ1 hemoglobin, theta 1 -0.00515178
NFE2L2 nuclear factor, erythroid 2-like 2 -0.00514607
VTN vitronectin -0.00514604
HOXA10 homeobox A10 -0.0051428
SELL selectin L -0.00514227
FST follistatin -0.00514114
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor -0.00514098
ASGR2 asialoglycoprotein receptor 2 -0.00513552
CD14 CD14 molecule -0.00512968
BIN2 bridging integrator 2 -0.0051282
GNLY granulysin -0.00511773
ABHD4 abhydrolase domain containing 4 -0.00510942
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00509486
RFK riboflavin kinase -0.00508739
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.00507607
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 -0.00507287
LOXL1 lysyl oxidase-like 1 -0.00505381
STAT4 signal transducer and activator of transcription 4 -0.00503148
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) -0.00501705
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.00501356
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -0.00500822
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.00500371
KLHDC3 kelch domain containing 3 -0.0049996
GZMK granzyme K (granzyme 3; tryptase II) -0.00499621
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -0.00497628
NEK7 NIMA-related kinase 7 -0.00497462
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B -0.00495666
LEPR leptin receptor -0.00495601
TFRC transferrin receptor -0.00494957
G0S2 G0/G1 switch 2 -0.00494618
PGLYRP1 peptidoglycan recognition protein 1 -0.00494012
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog -0.00492764
ZNF395 zinc finger protein 395 -0.00492427
APOB apolipoprotein B -0.00492384
SEPP1 selenoprotein P, plasma, 1 -0.00491878
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain -0.00491585
KLRK1 killer cell lectin-like receptor subfamily K, member 1 -0.00491272
ABHD11 abhydrolase domain containing 11 -0.00491035
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00490323
ETFB electron-transfer-flavoprotein, beta polypeptide -0.00489198
FPR1 formyl peptide receptor 1 -0.00487807
GLUD1 glutamate dehydrogenase 1 -0.00486917
HIST1H2AC histone cluster 1, H2ac -0.0048611
CD69 CD69 molecule -0.00485467
DDIT3 DNA-damage-inducible transcript 3 -0.00484892
CTSZ cathepsin Z -0.00484514
MCOLN1 mucolipin 1 -0.00484184
PAX6 paired box 6 -0.00483766
CD2 CD2 molecule -0.00483411
TSPAN13 tetraspanin 13 -0.00482816
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -0.00481228
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta -0.00480121
LST1 leukocyte specific transcript 1 -0.00479551
TFR2 transferrin receptor 2 -0.00479279
TWIST1 twist family bHLH transcription factor 1 -0.00479159
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00478251
ZBTB18 zinc finger and BTB domain containing 18 -0.00478244
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 -0.00477405
RB1 retinoblastoma 1 -0.00476145
UBXN6 UBX domain protein 6 -0.00475957
SYNE3 spectrin repeat containing, nuclear envelope family member 3 -0.00475664
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 -0.0047548
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00475331
KIAA0513 KIAA0513 -0.00475154
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -0.0047497
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 -0.00474915
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00474875
SHLD2 shieldin complex subunit 2 -0.00473893
DEPTOR DEP domain containing MTOR-interacting protein -0.0047384