CXCR1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description chemokine (C-X-C motif) receptor 1|The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3577)
External Link http://www.ncbi.nlm.nih.gov/gene/3577
Similar Terms
Downloads & Tools

Genes

30 interacting proteins for CXCR1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ADRA1A adrenoceptor alpha 1A
ADRBK1 adrenergic, beta, receptor kinase 1
CDK1 cyclin-dependent kinase 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL6 chemokine (C-X-C motif) ligand 6
CXCR2 chemokine (C-X-C motif) receptor 2
DNM1 dynamin 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GRK6 G protein-coupled receptor kinase 6
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
JAK3 Janus kinase 3
PDCD6IP programmed cell death 6 interacting protein
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
RAB5A RAB5A, member RAS oncogene family
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLA2 Src-like-adaptor 2
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
TUBA1A tubulin, alpha 1a
UBE2C ubiquitin-conjugating enzyme E2C