| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | chemokine (C-X-C motif) receptor 3|This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011] (NCBI Entrez Gene Database, 2833) |
| External Link | https://ncbi.nlm.nih.gov/gene/2833 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the CXCR3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.0149574 |
| RB1 | retinoblastoma 1 | 0.0135107 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0119744 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.0105132 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0102762 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.0100979 |
| CDC20 | cell division cycle 20 | 0.0100004 |
| LOXL1 | lysyl oxidase-like 1 | 0.00997211 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00983091 |
| MCOLN1 | mucolipin 1 | 0.00971695 |
| TADA2A | transcriptional adaptor 2A | 0.00945628 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.00945343 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 0.00941529 |
| MEF2C | myocyte enhancer factor 2C | 0.0094123 |
| TMSB15A | thymosin beta 15a | 0.00940472 |
| KRT7 | keratin 7, type II | 0.00939941 |
| TPD52 | tumor protein D52 | 0.00917307 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.0090169 |
| HOPX | HOP homeobox | 0.00884458 |
| CPM | carboxypeptidase M | 0.00876068 |
| F2R | coagulation factor II (thrombin) receptor | 0.0086588 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00864511 |
| C9 | complement component 9 | 0.00830408 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00825807 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00822932 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00819347 |
| TMEM176B | transmembrane protein 176B | 0.008103 |
| RGS1 | regulator of G-protein signaling 1 | 0.00807042 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00804782 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.0080263 |
| NFIB | nuclear factor I/B | 0.00797673 |
| CCDC86 | coiled-coil domain containing 86 | 0.00795347 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.00792282 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00790754 |
| DACH1 | dachshund family transcription factor 1 | 0.00789564 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00787565 |
| FSTL1 | follistatin-like 1 | 0.00785316 |
| FHL1 | four and a half LIM domains 1 | 0.00783464 |
| C7 | complement component 7 | 0.00776034 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00765798 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00762851 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00757761 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00757154 |
| NES | nestin | 0.00751589 |
| KLF6 | Kruppel-like factor 6 | 0.0074401 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 0.00743103 |
| PRMT1 | protein arginine methyltransferase 1 | 0.00738071 |
| CD81 | CD81 molecule | 0.00738049 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | 0.00732846 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | 0.00732351 |
| FAR2 | fatty acyl CoA reductase 2 | 0.00730057 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | 0.0072654 |
| TSPAN12 | tetraspanin 12 | 0.00724662 |
| CD53 | CD53 molecule | 0.00724207 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.00722314 |
| PDLIM3 | PDZ and LIM domain 3 | 0.00721594 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 0.00719986 |
| ANOS1 | anosmin 1 | 0.00719543 |
| NPY | neuropeptide Y | 0.00719495 |
| THY1 | Thy-1 cell surface antigen | 0.00719073 |
| KLHL41 | kelch-like family member 41 | 0.00718523 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00712024 |
| DCN | decorin | 0.00709791 |
| PSAP | prosaposin | 0.00706932 |
| CDO1 | cysteine dioxygenase type 1 | 0.00706207 |
| UGT2B4 | UDP glucuronosyltransferase 2 family, polypeptide B4 | 0.00704958 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00703109 |
| SDC1 | syndecan 1 | 0.00702233 |
| FPGS | folylpolyglutamate synthase | 0.00700355 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 | 0.00698759 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.00698593 |
| MYBPC1 | myosin binding protein C, slow type | 0.00695256 |
| CCP110 | centriolar coiled coil protein 110kDa | 0.0069483 |
| CRIP2 | cysteine-rich protein 2 | 0.0069126 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.00689998 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 0.00686838 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00686365 |
| AOX1 | aldehyde oxidase 1 | 0.0068412 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00680197 |
| COLEC11 | collectin sub-family member 11 | 0.00679176 |
| CD93 | CD93 molecule | 0.0067511 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | 0.00674674 |
| BGN | biglycan | 0.00671577 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 0.00670661 |
| ENO3 | enolase 3 (beta, muscle) | 0.00670322 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00668593 |
| HBB | hemoglobin, beta | 0.0066658 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.00665344 |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.00663282 |
| ZW10 | zw10 kinetochore protein | 0.00660242 |
| LIG1 | ligase I, DNA, ATP-dependent | 0.00658065 |
| GAL | galanin/GMAP prepropeptide | 0.0065717 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00652044 |
| CYTIP | cytohesin 1 interacting protein | 0.00648068 |
| RGS5 | regulator of G-protein signaling 5 | 0.00647346 |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.00647298 |
| CD320 | CD320 molecule | 0.00646143 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00644834 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.0064213 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00639324 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00637545 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00636882 |
| ZFHX4 | zinc finger homeobox 4 | 0.00636322 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 0.00635521 |
| RXYLT1 | ribitol xylosyltransferase 1 | 0.00633857 |
| NNMT | nicotinamide N-methyltransferase | 0.00632349 |
| CD163 | CD163 molecule | 0.00631356 |
| BCHE | butyrylcholinesterase | 0.00631156 |
| UBXN7 | UBX domain protein 7 | 0.00630025 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00626513 |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.00626305 |
| ATP5F1D | ATP synthase F1 subunit delta | 0.00624639 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00624076 |
| IRS2 | insulin receptor substrate 2 | 0.00622589 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | 0.0062162 |
| FUS | FUS RNA binding protein | 0.00620809 |
| CLDN10 | claudin 10 | 0.00620633 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00616669 |
| MYOT | myotilin | 0.00614226 |
| CNR1 | cannabinoid receptor 1 (brain) | 0.00610417 |
| PRPF19 | pre-mRNA processing factor 19 | 0.00608399 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00603675 |
| PPID | peptidylprolyl isomerase D | 0.00603204 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.00603125 |
| CRP | C-reactive protein, pentraxin-related | 0.00602286 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00599313 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00597869 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 0.00597636 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00595988 |
| LYZ | lysozyme | 0.00595486 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00595066 |
| MYRIP | myosin VIIA and Rab interacting protein | 0.00593603 |
| ACTN1 | actinin, alpha 1 | 0.00592937 |
| SACS | sacsin molecular chaperone | 0.00592664 |
| CTSS | cathepsin S | 0.00592339 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B | 0.00592319 |
| UNG | uracil-DNA glycosylase | 0.00592292 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 0.00592063 |
| TSPAN8 | tetraspanin 8 | 0.00591771 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) | 0.00590216 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 0.00588566 |
| GANAB | glucosidase, alpha; neutral AB | 0.00586879 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.00585017 |
| JADE1 | jade family PHD finger 1 | 0.00583041 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00582429 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00581594 |
| PALMD | palmdelphin | 0.00580984 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00580775 |
| C1ORF115 | chromosome 1 open reading frame 115 | 0.00580127 |
| TYRP1 | tyrosinase-related protein 1 | 0.00579847 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | 0.00578956 |
| CHN2 | chimerin 2 | 0.00578874 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | 0.00575232 |
| NTAN1 | N-terminal asparagine amidase | 0.00573516 |
| LAPTM5 | lysosomal protein transmembrane 5 | 0.00572427 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.00572191 |
| UQCRC1 | ubiquinol-cytochrome c reductase core protein I | 0.00569904 |
| S100A8 | S100 calcium binding protein A8 | 0.00569615 |
| RPL14 | ribosomal protein L14 | 0.0056926 |
| PLIN3 | perilipin 3 | 0.0056923 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.00568271 |
| TWIST1 | twist family bHLH transcription factor 1 | 0.00567741 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | 0.00566434 |
| CD14 | CD14 molecule | 0.00564494 |
| CYP2C8 | cytochrome P450, family 2, subfamily C, polypeptide 8 | 0.00563162 |
| PRR11 | proline rich 11 | 0.00563033 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.00562576 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00562309 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.00561785 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 0.00560464 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00559656 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00555274 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00555104 |
| SEPTIN11 | septin 11 | 0.00552208 |
| SPON2 | spondin 2, extracellular matrix protein | 0.00551446 |
| DHFR | dihydrofolate reductase | 0.00551234 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00549289 |
| NCF2 | neutrophil cytosolic factor 2 | 0.00548919 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.00548157 |
| ACTN2 | actinin, alpha 2 | 0.00548097 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial | 0.0054786 |
| FABP7 | fatty acid binding protein 7, brain | 0.00546875 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.00546536 |
| TNNI1 | troponin I type 1 (skeletal, slow) | 0.00546225 |
| FEN1 | flap structure-specific endonuclease 1 | 0.00545446 |
| CCNF | cyclin F | 0.00543596 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 | 0.00543232 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | 0.00542881 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.00542597 |
| RAPSN | receptor-associated protein of the synapse | 0.00542587 |
| ANXA5 | annexin A5 | 0.00542366 |
| MTA1 | metastasis associated 1 | 0.00541059 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00539721 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | 0.00539419 |
| CD52 | CD52 molecule | 0.00538519 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.00536468 |
| RAPGEF4 | Rap guanine nucleotide exchange factor (GEF) 4 | 0.00535354 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 | 0.0053354 |
| FKBP2 | FK506 binding protein 2, 13kDa | 0.00531531 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) | 0.00530741 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00530547 |
| EGR2 | early growth response 2 | 0.00529405 |
| GPX1 | glutathione peroxidase 1 | 0.00529389 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00526523 |
| NDUFAF3 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 | 0.00524832 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00524632 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00524587 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.00522908 |
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 0.00522782 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 0.00522113 |
| AIF1 | allograft inflammatory factor 1 | 0.00521715 |
| G0S2 | G0/G1 switch 2 | 0.00520805 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | 0.0052035 |
| ALOX15B | arachidonate 15-lipoxygenase, type B | 0.00519659 |
| MCM5 | minichromosome maintenance complex component 5 | 0.00519395 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00519212 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00518748 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.00517906 |
| CLU | clusterin | 0.00515747 |
| APCS | amyloid P component, serum | 0.00514475 |
| INSR | insulin receptor | 0.0051419 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00514056 |
| ADI1 | acireductone dioxygenase 1 | 0.0051236 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00510444 |
| FANCL | Fanconi anemia, complementation group L | 0.00510239 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.00509284 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.005085 |
| NANOG | Nanog homeobox | 0.00508467 |
| MAP7 | microtubule-associated protein 7 | 0.00508072 |
| SRGN | serglycin | 0.00507184 |
| DENND4C | DENN/MADD domain containing 4C | 0.00507 |
| CD200 | CD200 molecule | 0.00506853 |
| NPTX2 | neuronal pentraxin II | 0.00506664 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00505803 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.00505356 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.00504984 |
| SLN | sarcolipin | 0.00504351 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00504021 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 0.00503757 |
| LAT2 | linker for activation of T cells family, member 2 | 0.005033 |
| PFAS | phosphoribosylformylglycinamidine synthase | 0.00502882 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00502101 |
| C5AR1 | complement component 5a receptor 1 | 0.00501077 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00500588 |
| ELP5 | elongator acetyltransferase complex subunit 5 | 0.00500561 |
| GPM6A | glycoprotein M6A | 0.00499066 |
| ZNF136 | zinc finger protein 136 | 0.00498466 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00498339 |
| RHOA | ras homolog family member A | 0.00497576 |
| SH2B2 | SH2B adaptor protein 2 | 0.00497523 |
| Symbol | Name | Standardized Value |
|---|---|---|
| XIC | X chromosome inactivation center | -0.0131107 |
| CHP1 | calcineurin-like EF-hand protein 1 | -0.0115333 |
| TLCD3A | TLC domain containing 3A | -0.0107452 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0103312 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00959461 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00953131 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00940086 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00904209 |
| KRT15 | keratin 15, type I | -0.00902469 |
| STC2 | stanniocalcin 2 | -0.0088983 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00882329 |
| STK26 | serine/threonine protein kinase 26 | -0.00877396 |
| KRT19 | keratin 19, type I | -0.00851149 |
| GPC3 | glypican 3 | -0.0084658 |
| KYNU | kynureninase | -0.00846013 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00844924 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00840406 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00831374 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00829053 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00826988 |
| FGG | fibrinogen gamma chain | -0.00824147 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00813849 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00813608 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00797384 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00789153 |
| AFP | alpha-fetoprotein | -0.00770353 |
| DLX5 | distal-less homeobox 5 | -0.00764955 |
| MX2 | MX dynamin-like GTPase 2 | -0.00760934 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00756486 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00755505 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0075397 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.00751787 |
| CA12 | carbonic anhydrase XII | -0.00750671 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00748937 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00745398 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.00741908 |
| GCH1 | GTP cyclohydrolase 1 | -0.00733871 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00725626 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00724821 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00722749 |
| PEG3 | paternally expressed 3 | -0.00721782 |
| MATN2 | matrilin 2 | -0.00718665 |
| JAG1 | jagged 1 | -0.00718615 |
| ANXA4 | annexin A4 | -0.0071801 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00717958 |
| TRIB3 | tribbles pseudokinase 3 | -0.0071352 |
| CLTB | clathrin, light chain B | -0.00708346 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00705206 |
| SVIL | supervillin | -0.00703017 |
| KDM5A | lysine (K)-specific demethylase 5A | -0.00696887 |
| TXNDC9 | thioredoxin domain containing 9 | -0.0069162 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | -0.00688973 |
| IFI44L | interferon-induced protein 44-like | -0.00687249 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00683392 |
| TRIM22 | tripartite motif containing 22 | -0.00680113 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00676 |
| WT1 | Wilms tumor 1 | -0.00674881 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00673546 |
| FGB | fibrinogen beta chain | -0.00667389 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | -0.00666775 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00661596 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.00658235 |
| MX1 | MX dynamin-like GTPase 1 | -0.00653641 |
| PANK2 | pantothenate kinase 2 | -0.00649802 |
| RGS10 | regulator of G-protein signaling 10 | -0.00648436 |
| RPA3 | replication protein A3, 14kDa | -0.0064589 |
| PRSS8 | protease, serine, 8 | -0.00642594 |
| HOXC10 | homeobox C10 | -0.0063745 |
| COL9A2 | collagen, type IX, alpha 2 | -0.00637244 |
| ADD3 | adducin 3 (gamma) | -0.00636352 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.0063563 |
| CNTN1 | contactin 1 | -0.00628678 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00626727 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00619347 |
| KLHL21 | kelch-like family member 21 | -0.00618528 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00616095 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00613463 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.00611949 |
| PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta | -0.00609517 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.00609121 |
| RCAN1 | regulator of calcineurin 1 | -0.00608554 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.00605964 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00605902 |
| ARG2 | arginase 2 | -0.00605717 |
| YAP1 | Yes-associated protein 1 | -0.00605569 |
| KRT16 | keratin 16, type I | -0.00604963 |
| RALB | v-ral simian leukemia viral oncogene homolog B | -0.00604642 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00603342 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | -0.00599847 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00599327 |
| EMP1 | epithelial membrane protein 1 | -0.00599218 |
| TOB1 | transducer of ERBB2, 1 | -0.00597947 |
| PENK | proenkephalin | -0.00590435 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00589273 |
| AOC1 | amine oxidase, copper containing 1 | -0.00589109 |
| SPRR2B | small proline-rich protein 2B | -0.00588815 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | -0.00587826 |
| GDF15 | growth differentiation factor 15 | -0.00587645 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00586593 |
| MINK1 | misshapen-like kinase 1 | -0.00583524 |
| ANXA9 | annexin A9 | -0.00581832 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00581034 |
| F5 | coagulation factor V (proaccelerin, labile factor) | -0.00580054 |
| CFB | complement factor B | -0.00578171 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | -0.00577821 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00576652 |
| C3ORF52 | chromosome 3 open reading frame 52 | -0.00576254 |
| GPX2 | glutathione peroxidase 2 | -0.00575227 |
| ZNF148 | zinc finger protein 148 | -0.00574688 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00574474 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00573335 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.00572255 |
| PRODH | proline dehydrogenase (oxidase) 1 | -0.00570609 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.00568193 |
| SPAG1 | sperm associated antigen 1 | -0.00565779 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00565547 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.00564686 |
| PEG10 | paternally expressed 10 | -0.00563524 |
| APOB | apolipoprotein B | -0.00562484 |
| THBD | thrombomodulin | -0.00561289 |
| NTS | neurotensin | -0.00560538 |
| FOXC1 | forkhead box C1 | -0.00558391 |
| PIR | pirin (iron-binding nuclear protein) | -0.00557991 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0055719 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.0055634 |
| GSTO1 | glutathione S-transferase omega 1 | -0.00555143 |
| TNC | tenascin C | -0.00554515 |
| HDAC9 | histone deacetylase 9 | -0.00552984 |
| FGA | fibrinogen alpha chain | -0.00551881 |
| MUC1 | mucin 1, cell surface associated | -0.0055173 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | -0.00550637 |
| MOCOS | molybdenum cofactor sulfurase | -0.00548615 |
| SEC24A | SEC24 family member A | -0.00548053 |
| LIMK2 | LIM domain kinase 2 | -0.00547772 |
| IGSF1 | immunoglobulin superfamily, member 1 | -0.00545718 |
| MXI1 | MAX interactor 1, dimerization protein | -0.00544931 |
| FOLR1 | folate receptor 1 (adult) | -0.00544632 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00544462 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00544113 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00542048 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00542013 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00541656 |
| ACKR3 | atypical chemokine receptor 3 | -0.00541279 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | -0.00540513 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.00538594 |
| GLUD1 | glutamate dehydrogenase 1 | -0.00537669 |
| PDCD10 | programmed cell death 10 | -0.0053541 |
| ACAN | aggrecan | -0.00535175 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00533801 |
| CD7 | CD7 molecule | -0.00532443 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.00530599 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | -0.00529809 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.00529631 |
| HK2 | hexokinase 2 | -0.00529428 |
| RTP4 | receptor (chemosensory) transporter protein 4 | -0.0052927 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | -0.00528629 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00528306 |
| IL1RN | interleukin 1 receptor antagonist | -0.00527884 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -0.00527345 |
| FAM162A | family with sequence similarity 162, member A | -0.00526743 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | -0.00526408 |
| LOX | lysyl oxidase | -0.00525638 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00524487 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00524225 |
| PYCARD | PYD and CARD domain containing | -0.00521937 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00520867 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00519183 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.00518737 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00516799 |
| KRT14 | keratin 14, type I | -0.00516769 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.00516695 |
| ARF3 | ADP-ribosylation factor 3 | -0.00516482 |
| LBH | limb bud and heart development | -0.00515731 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | -0.00515654 |
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 | -0.00515396 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00515197 |
| TJP2 | tight junction protein 2 | -0.0051414 |
| IFI44 | interferon-induced protein 44 | -0.00513939 |
| PRAME | preferentially expressed antigen in melanoma | -0.00513746 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.00513745 |
| GSN | gelsolin | -0.00512629 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | -0.00509744 |
| EAPP | E2F-associated phosphoprotein | -0.00509367 |
| RIT1 | Ras-like without CAAX 1 | -0.00508208 |
| DUSP9 | dual specificity phosphatase 9 | -0.00506846 |
| VEGFA | vascular endothelial growth factor A | -0.00504945 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | -0.00504558 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.00504081 |
| CETN2 | centrin, EF-hand protein, 2 | -0.00502888 |
| FCGBP | Fc fragment of IgG binding protein | -0.00501747 |
| NUP50 | nucleoporin 50kDa | -0.00501718 |
| HIC2 | hypermethylated in cancer 2 | -0.00501672 |
| LRRC8D | leucine rich repeat containing 8 family, member D | -0.00501326 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | -0.0050049 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00499855 |
| IL6ST | interleukin 6 signal transducer | -0.00499382 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00499099 |
| RAP2A | RAP2A, member of RAS oncogene family | -0.00498795 |
| KRT23 | keratin 23, type I | -0.00498784 |
| EPHA4 | EPH receptor A4 | -0.00498583 |
| VIL1 | villin 1 | -0.00497562 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00496309 |
| PTGES | prostaglandin E synthase | -0.00494082 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | -0.00493683 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.00493 |
| SELENBP1 | selenium binding protein 1 | -0.00491554 |
| ACSF2 | acyl-CoA synthetase family member 2 | -0.00491501 |
| LYPLA1 | lysophospholipase I | -0.00490844 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00489414 |
| KIAA0513 | KIAA0513 | -0.0048911 |
| ENDOD1 | endonuclease domain containing 1 | -0.00489077 |
| MICB | MHC class I polypeptide-related sequence B | -0.00487724 |
| HAS1 | hyaluronan synthase 1 | -0.00486741 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00485857 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00485474 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00485123 |
| VGLL1 | vestigial-like family member 1 | -0.00484874 |
| BPGM | 2,3-bisphosphoglycerate mutase | -0.00483548 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00482942 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.0048274 |
| DSP | desmoplakin | -0.00482653 |
| PLPP3 | phospholipid phosphatase 3 | -0.00481943 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | -0.00480432 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.00480365 |
| DSG3 | desmoglein 3 | -0.0048031 |
| DCP2 | decapping mRNA 2 | -0.00480077 |
| GSK3B | glycogen synthase kinase 3 beta | -0.00478879 |
| GRAMD2B | GRAM domain containing 2B | -0.00477564 |
| UVRAG | UV radiation resistance associated | -0.00474503 |
| BTG2 | BTG family, member 2 | -0.00474261 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.0047391 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.00473854 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00473081 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -0.00472951 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.00472566 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein | -0.00470827 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00470686 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.00469336 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.00469073 |
| KLF9 | Kruppel-like factor 9 | -0.00468742 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00468135 |
| SPEN | spen family transcriptional repressor | -0.00467329 |
| CSRP1 | cysteine and glycine-rich protein 1 | -0.00466452 |
| TMEM131 | transmembrane protein 131 | -0.00465686 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0046503 |
| HOXD1 | homeobox D1 | -0.00464341 |
| GOLIM4 | golgi integral membrane protein 4 | -0.00463859 |
| HGD | homogentisate 1,2-dioxygenase | -0.00463626 |
| NOTCH2 | notch 2 | -0.00462225 |
