| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | chemokine (C-X-C motif) receptor 4|This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7852) |
| External Link | https://ncbi.nlm.nih.gov/gene/7852 |
| Similar Terms | |
| Downloads & Tools |
477 genes differentially expressed following the CXCR4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 0.018351 |
| OLFM4 | olfactomedin 4 | 0.0161864 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.0154207 |
| LTF | lactotransferrin | 0.0152403 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.0146059 |
| RGS4 | regulator of G-protein signaling 4 | 0.0144253 |
| GATA2 | GATA binding protein 2 | 0.0144153 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.014413 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 0.0142472 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.0137028 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0136243 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.0134861 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0127388 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.0127273 |
| NPTX2 | neuronal pentraxin II | 0.0124775 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.012401 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.012357 |
| PITX3 | paired-like homeodomain 3 | 0.0120282 |
| ASRGL1 | asparaginase like 1 | 0.0120045 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0117307 |
| ELANE | elastase, neutrophil expressed | 0.0117235 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.0116887 |
| GUCY2C | guanylate cyclase 2C | 0.0116845 |
| PXDN | peroxidasin | 0.0116164 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0115849 |
| CSTA | cystatin A (stefin A) | 0.0115592 |
| FBN2 | fibrillin 2 | 0.011442 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.0112206 |
| ANO10 | anoctamin 10 | 0.0111473 |
| REG1A | regenerating islet-derived 1 alpha | 0.0111081 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0109566 |
| NTS | neurotensin | 0.0108096 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.0107868 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0107203 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0105708 |
| ACP3 | acid phosphatase 3 | 0.0104475 |
| SVIL | supervillin | 0.0104333 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0104296 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.010374 |
| TPM2 | tropomyosin 2 (beta) | 0.0103305 |
| SRGN | serglycin | 0.010225 |
| MEIS2 | Meis homeobox 2 | 0.0101939 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.0101775 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.0101227 |
| PLAT | plasminogen activator, tissue | 0.0100796 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.0100582 |
| MAP7 | microtubule-associated protein 7 | 0.0100536 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0100094 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00999623 |
| TPK1 | thiamin pyrophosphokinase 1 | 0.0097499 |
| MSMB | microseminoprotein, beta- | 0.00973557 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0096818 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00965318 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.0095769 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00955408 |
| LXN | latexin | 0.00952651 |
| ANXA2 | annexin A2 | 0.009472 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00945872 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00930383 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00930222 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00927696 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | 0.00923798 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00915728 |
| MGAM | maltase-glucoamylase | 0.00914851 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.00914745 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00908961 |
| NEBL | nebulette | 0.00908631 |
| TMEM47 | transmembrane protein 47 | 0.00902204 |
| TMSB15A | thymosin beta 15a | 0.00898048 |
| GOLM1 | golgi membrane protein 1 | 0.00896673 |
| CAMP | cathelicidin antimicrobial peptide | 0.00896536 |
| EMP3 | epithelial membrane protein 3 | 0.00891857 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.00891656 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.0089121 |
| CETN2 | centrin, EF-hand protein, 2 | 0.0088269 |
| NREP | neuronal regeneration related protein | 0.00882096 |
| COL5A2 | collagen, type V, alpha 2 | 0.00880398 |
| CLDN10 | claudin 10 | 0.00878429 |
| MYBPC1 | myosin binding protein C, slow type | 0.00876089 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00872167 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00871442 |
| H1-2 | H1.2 linker histone, cluster member | 0.00870965 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00870946 |
| GALC | galactosylceramidase | 0.00865141 |
| TSPAN8 | tetraspanin 8 | 0.00864485 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.00859674 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.00857292 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00856582 |
| H1-10 | H1.10 linker histone | 0.00855056 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00854294 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00845863 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 0.00841555 |
| SIRPA | signal-regulatory protein alpha | 0.00838347 |
| AZU1 | azurocidin 1 | 0.0083491 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.00834145 |
| RNF144A | ring finger protein 144A | 0.00833379 |
| TUBA1A | tubulin, alpha 1a | 0.00831372 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.008298 |
| TP53I3 | tumor protein p53 inducible protein 3 | 0.0082827 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00826722 |
| CCNF | cyclin F | 0.0082259 |
| MAL | mal, T-cell differentiation protein | 0.00822347 |
| OGN | osteoglycin | 0.00821795 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.00819755 |
| DPP4 | dipeptidyl-peptidase 4 | 0.00813843 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.0080642 |
| SSPN | sarcospan | 0.00805543 |
| FABP6 | fatty acid binding protein 6, ileal | 0.00804472 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00804411 |
| PDLIM4 | PDZ and LIM domain 4 | 0.00801885 |
| CNN3 | calponin 3, acidic | 0.00801494 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00796584 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00796185 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00793549 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.00791716 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00788344 |
| LYZ | lysozyme | 0.00787283 |
| BAX | BCL2-associated X protein | 0.00780956 |
| TMEM38B | transmembrane protein 38B | 0.00780583 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00776736 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.00775971 |
| VCAN | versican | 0.00775577 |
| TMC5 | transmembrane channel-like 5 | 0.00775397 |
| LOXL2 | lysyl oxidase-like 2 | 0.00773964 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00767735 |
| TSPAN1 | tetraspanin 1 | 0.00764042 |
| NNMT | nicotinamide N-methyltransferase | 0.00762933 |
| WLS | wntless Wnt ligand secretion mediator | 0.00757685 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.00755681 |
| GAS1 | growth arrest-specific 1 | 0.00755578 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00753765 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00753066 |
| EDN3 | endothelin 3 | 0.00752073 |
| CRYM | crystallin, mu | 0.00751305 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.00749862 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00749474 |
| WFDC1 | WAP four-disulfide core domain 1 | 0.0074383 |
| PRAME | preferentially expressed antigen in melanoma | 0.00743659 |
| MORC4 | MORC family CW-type zinc finger 4 | 0.00743087 |
| GAL | galanin/GMAP prepropeptide | 0.00739046 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.00737535 |
| MDFIC | MyoD family inhibitor domain containing | 0.00737013 |
| CCK | cholecystokinin | 0.00736478 |
| NPY | neuropeptide Y | 0.007364 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00736254 |
| FAR2 | fatty acyl CoA reductase 2 | 0.0073528 |
| BICC1 | BicC family RNA binding protein 1 | 0.00734988 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00734749 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00734573 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00729783 |
| PON2 | paraoxonase 2 | 0.00729733 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00729222 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00728558 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | 0.00727931 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | 0.00724739 |
| EMX2 | empty spiracles homeobox 2 | 0.00724734 |
| GOLT1B | golgi transport 1B | 0.00724382 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00724041 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00723004 |
| XIC | X chromosome inactivation center | 0.00721118 |
| CALML5 | calmodulin-like 5 | 0.00720922 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.00720221 |
| NOTCH2NL | notch 2 N-terminal like | 0.00720104 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | 0.00718584 |
| ADD3 | adducin 3 (gamma) | 0.0071858 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00716623 |
| KLK10 | kallikrein-related peptidase 10 | 0.00715395 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.00715392 |
| PLSCR4 | phospholipid scramblase 4 | 0.00714331 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.00711503 |
| NUP85 | nucleoporin 85kDa | 0.00709267 |
| PDZD8 | PDZ domain containing 8 | 0.00708977 |
| NMU | neuromedin U | 0.00708936 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.00708386 |
| REG1B | regenerating islet-derived 1 beta | 0.00706997 |
| FABP7 | fatty acid binding protein 7, brain | 0.00706473 |
| PRKCA | protein kinase C, alpha | 0.00703952 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00703062 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00699684 |
| OCRL | oculocerebrorenal syndrome of Lowe | 0.00699254 |
| EVI2A | ecotropic viral integration site 2A | 0.00697963 |
| CCNB2 | cyclin B2 | 0.00697841 |
| AGTR1 | angiotensin II receptor, type 1 | 0.00697341 |
| SMPX | small muscle protein, X-linked | 0.00697159 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00695597 |
| TMEM135 | transmembrane protein 135 | 0.00695373 |
| EPAS1 | endothelial PAS domain protein 1 | 0.00694992 |
| KLK8 | kallikrein-related peptidase 8 | 0.0069285 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0069134 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00690466 |
| ABLIM1 | actin binding LIM protein 1 | 0.00689994 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 | 0.00686717 |
| KLF6 | Kruppel-like factor 6 | 0.00684994 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00684688 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.00683435 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00682961 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 | 0.00680342 |
| S100A12 | S100 calcium binding protein A12 | 0.006792 |
| KRT7 | keratin 7, type II | 0.00679066 |
| QPRT | quinolinate phosphoribosyltransferase | 0.0067769 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.00676799 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00676476 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00676339 |
| S100A7 | S100 calcium binding protein A7 | 0.00674426 |
| PLP1 | proteolipid protein 1 | 0.00674184 |
| RGS10 | regulator of G-protein signaling 10 | 0.0067215 |
| FAM111A | family with sequence similarity 111, member A | 0.00670824 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.00669394 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.00668623 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00668527 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 0.00668103 |
| PAEP | progestagen-associated endometrial protein | 0.00667787 |
| GPX1 | glutathione peroxidase 1 | 0.00667374 |
| COQ9 | coenzyme Q9 | 0.0066692 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.00664861 |
| DUOX2 | dual oxidase 2 | 0.00662708 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00661752 |
| FASN | fatty acid synthase | 0.00660847 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.00660249 |
| LACTB2 | lactamase, beta 2 | 0.00658571 |
| DGKZ | diacylglycerol kinase, zeta | 0.00656965 |
| CALR | calreticulin | 0.00656813 |
| GYG1 | glycogenin 1 | 0.00656222 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00655474 |
| PGAP3 | post-GPI attachment to proteins 3 | 0.00655319 |
| CBFB | core-binding factor, beta subunit | 0.006542 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00653562 |
| WASHC4 | WASH complex subunit 4 | 0.00652029 |
| WWC1 | WW and C2 domain containing 1 | 0.00651872 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | 0.00651702 |
| UPP1 | uridine phosphorylase 1 | 0.00649794 |
| TADA2A | transcriptional adaptor 2A | 0.00646355 |
| STXBP6 | syntaxin binding protein 6 (amisyn) | 0.00645105 |
| REG3A | regenerating islet-derived 3 alpha | 0.00643645 |
| FDXR | ferredoxin reductase | 0.00643244 |
| CAST | calpastatin | 0.00641229 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.00640655 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00640215 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00639961 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00639703 |
| STOM | stomatin | 0.00639084 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.00635186 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 0.00631402 |
| ADRA2A | adrenoceptor alpha 2A | 0.00631296 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CLU | clusterin | -0.0236694 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0183638 |
| CD163 | CD163 molecule | -0.016622 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.0140197 |
| DSP | desmoplakin | -0.013752 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0137482 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0129746 |
| SYNGR3 | synaptogyrin 3 | -0.0129313 |
| EFHD1 | EF-hand domain family, member D1 | -0.0128317 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.0125411 |
| TMEM176B | transmembrane protein 176B | -0.012464 |
| TSPAN7 | tetraspanin 7 | -0.0124417 |
| IFI44L | interferon-induced protein 44-like | -0.0123038 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0117801 |
| GPX3 | glutathione peroxidase 3 | -0.0115022 |
| C1QA | complement component 1, q subcomponent, A chain | -0.0112754 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0111896 |
| SFTPB | surfactant protein B | -0.0108345 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0104778 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0104709 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0103878 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0103872 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0101828 |
| DUSP5 | dual specificity phosphatase 5 | -0.0101536 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0101127 |
| CLEC3B | C-type lectin domain family 3, member B | -0.0100714 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0100567 |
| SOCS2 | suppressor of cytokine signaling 2 | -0.00996663 |
| IRF7 | interferon regulatory factor 7 | -0.00978029 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | -0.00977741 |
| CD14 | CD14 molecule | -0.00974019 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00970491 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00967268 |
| GLUL | glutamate-ammonia ligase | -0.00957494 |
| IFI30 | interferon, gamma-inducible protein 30 | -0.00952527 |
| TOX3 | TOX high mobility group box family member 3 | -0.00950862 |
| IL7R | interleukin 7 receptor | -0.00931536 |
| GNAS | GNAS complex locus | -0.00928064 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00919826 |
| BRD2 | bromodomain containing 2 | -0.00911369 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00897169 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00889364 |
| KRT19 | keratin 19, type I | -0.00875382 |
| GPX2 | glutathione peroxidase 2 | -0.00869146 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.00867333 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00859319 |
| SIRT3 | sirtuin 3 | -0.00858526 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.00854974 |
| ZBED2 | zinc finger, BED-type containing 2 | -0.00854228 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00853567 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.00848367 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00846371 |
| TPD52 | tumor protein D52 | -0.00845867 |
| INSM1 | insulinoma-associated 1 | -0.0084126 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.00831435 |
| NVL | nuclear VCP-like | -0.00830665 |
| RBM47 | RNA binding motif protein 47 | -0.00828452 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00826117 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00826034 |
| REEP1 | receptor accessory protein 1 | -0.00817895 |
| MX1 | MX dynamin-like GTPase 1 | -0.0081598 |
| CA12 | carbonic anhydrase XII | -0.00815486 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00815279 |
| LAMB3 | laminin, beta 3 | -0.00812965 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.00811838 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00810806 |
| RGS16 | regulator of G-protein signaling 16 | -0.00806378 |
| CDV3 | CDV3 homolog (mouse) | -0.00803974 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00799872 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.00798663 |
| AREG | amphiregulin | -0.00797612 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.00793852 |
| MMP9 | matrix metallopeptidase 9 | -0.00792608 |
| SNX11 | sorting nexin 11 | -0.00791876 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00791761 |
| G0S2 | G0/G1 switch 2 | -0.0078953 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0078896 |
| THOC2 | THO complex 2 | -0.00786333 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.00784641 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00779677 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00773882 |
| DSE | dermatan sulfate epimerase | -0.00772342 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 | -0.00770231 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.0076873 |
| S100A9 | S100 calcium binding protein A9 | -0.00763783 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00763547 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00761238 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.00758807 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00752395 |
| CFH | complement factor H | -0.00751607 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00750927 |
| S100A8 | S100 calcium binding protein A8 | -0.0074983 |
| AMOTL2 | angiomotin like 2 | -0.0074327 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00742432 |
| USP18 | ubiquitin specific peptidase 18 | -0.00737369 |
| HP | haptoglobin | -0.00735264 |
| KYNU | kynureninase | -0.00730722 |
| COMP | cartilage oligomeric matrix protein | -0.0073038 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00726532 |
| DHRS1 | dehydrogenase/reductase (SDR family) member 1 | -0.00725452 |
| S100P | S100 calcium binding protein P | -0.00722267 |
| SPP2 | secreted phosphoprotein 2, 24kDa | -0.00719515 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | -0.00718 |
| SSX1 | synovial sarcoma, X breakpoint 1 | -0.00714859 |
| PPA1 | pyrophosphatase (inorganic) 1 | -0.00713911 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00712116 |
| LDHA | lactate dehydrogenase A | -0.00710729 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00705607 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | -0.00704611 |
| IL2RB | interleukin 2 receptor, beta | -0.00704599 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00703698 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.00703567 |
| RETREG2 | reticulophagy regulator family member 2 | -0.00701948 |
| VWF | von Willebrand factor | -0.00700775 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.00699109 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00698348 |
| CLDN4 | claudin 4 | -0.00694985 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | -0.00693833 |
| FRYL | FRY-like | -0.00693782 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00693372 |
| PRDX1 | peroxiredoxin 1 | -0.00692188 |
| CD81 | CD81 molecule | -0.00691065 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00689558 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.00689243 |
| BRD4 | bromodomain containing 4 | -0.00686276 |
| ATF3 | activating transcription factor 3 | -0.0068625 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00684318 |
| CES1 | carboxylesterase 1 | -0.00683054 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.0067664 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | -0.00676171 |
| KIF3B | kinesin family member 3B | -0.00672343 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00670769 |
| SQLE | squalene epoxidase | -0.00668219 |
| PLN | phospholamban | -0.00667587 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | -0.00664425 |
| SLBP | stem-loop binding protein | -0.00663842 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00663143 |
| NIPSNAP2 | nipsnap homolog 2 | -0.00662848 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00661733 |
| IER5 | immediate early response 5 | -0.0065895 |
| FOXG1 | forkhead box G1 | -0.00658798 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00658768 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00658198 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.00657131 |
| ACKR3 | atypical chemokine receptor 3 | -0.00656266 |
| AIM2 | absent in melanoma 2 | -0.00655651 |
| OXTR | oxytocin receptor | -0.00651851 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -0.00649456 |
| ZNHIT1 | zinc finger, HIT-type containing 1 | -0.00649293 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00648788 |
| HNMT | histamine N-methyltransferase | -0.00647218 |
| ATP9A | ATPase, class II, type 9A | -0.00645375 |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide | -0.00645054 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.00644571 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00644312 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0064309 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00642301 |
| SFTPA2 | surfactant protein A2 | -0.00640822 |
| EBI3 | Epstein-Barr virus induced 3 | -0.00640746 |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 | -0.00640462 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00639716 |
| CDO1 | cysteine dioxygenase type 1 | -0.00636656 |
| DIO1 | deiodinase, iodothyronine, type I | -0.00636613 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.00634809 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0063477 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.00633798 |
| DNASE1L3 | deoxyribonuclease I-like 3 | -0.00631877 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00630334 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | -0.00630313 |
| CCL21 | chemokine (C-C motif) ligand 21 | -0.00630124 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00627918 |
| STAB1 | stabilin 1 | -0.006274 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00626246 |
| NOTCH1 | notch 1 | -0.00625136 |
| NRN1 | neuritin 1 | -0.00624959 |
| SOWAHC | sosondowah ankyrin repeat domain family member C | -0.00624873 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00616495 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00616327 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00614886 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.00613497 |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 | -0.00611976 |
| HPR | haptoglobin-related protein | -0.00611583 |
| CCR7 | chemokine (C-C motif) receptor 7 | -0.00610192 |
| ABHD6 | abhydrolase domain containing 6 | -0.00609717 |
| ACOT13 | acyl-CoA thioesterase 13 | -0.00607936 |
| LIPG | lipase, endothelial | -0.00607767 |
| MAGEH1 | melanoma antigen family H1 | -0.0060716 |
| WISP2 | WNT1 inducible signaling pathway protein 2 | -0.00606067 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00605354 |
| F12 | coagulation factor XII (Hageman factor) | -0.00603528 |
| PLIN1 | perilipin 1 | -0.00603026 |
| HBB | hemoglobin, beta | -0.0060282 |
| HIP1 | huntingtin interacting protein 1 | -0.0060231 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | -0.00601622 |
| MELK | maternal embryonic leucine zipper kinase | -0.00598251 |
| POU2AF1 | POU class 2 associating factor 1 | -0.0059725 |
| SIX1 | SIX homeobox 1 | -0.00596309 |
| CLIC3 | chloride intracellular channel 3 | -0.00596289 |
| FGA | fibrinogen alpha chain | -0.00595919 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.00593718 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.00591199 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.00591119 |
| EFNA1 | ephrin-A1 | -0.00591017 |
| PUM1 | pumilio RNA-binding family member 1 | -0.00590715 |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 | -0.00590474 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0059032 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00589063 |
| CHI3L2 | chitinase 3-like 2 | -0.0058902 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | -0.00588757 |
| TALDO1 | transaldolase 1 | -0.00588478 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00587671 |
| SERTAD2 | SERTA domain containing 2 | -0.00587346 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00586963 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.00586878 |
| ZNF281 | zinc finger protein 281 | -0.00586806 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | -0.00585078 |
| TXLNA | taxilin alpha | -0.00584823 |
| GSE1 | Gse1 coiled-coil protein | -0.00583027 |
| CFD | complement factor D (adipsin) | -0.00581679 |
| STX6 | syntaxin 6 | -0.00581358 |
| MYOT | myotilin | -0.00581172 |
| CTR9 | CTR9, Paf1/RNA polymerase II complex component | -0.00581009 |
| RNF34 | ring finger protein 34, E3 ubiquitin protein ligase | -0.00580965 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | -0.00580679 |
| DMAC2L | distal membrane arm assembly component 2 like | -0.0058009 |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 | -0.00579407 |
| SUSD6 | sushi domain containing 6 | -0.0057872 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00578216 |
| SIK1 | salt-inducible kinase 1 | -0.00577986 |
| CD8A | CD8a molecule | -0.00576352 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.00575924 |
| CCDC86 | coiled-coil domain containing 86 | -0.00575214 |
| AHR | aryl hydrocarbon receptor | -0.00574231 |
