CYCLIN_D1_UP.V1 Gene Set

Dataset MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations
Category transcriptomics
Type gene perturbation
Description gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database)
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379 genes differentially expressed following the CYCLIN_D1_UP.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABLIM1 actin binding LIM protein 1
ADRA2A adrenoceptor alpha 2A
ADRA2B adrenoceptor alpha 2B
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ANPEP alanyl (membrane) aminopeptidase
APOA1 apolipoprotein A-I
APOC4 apolipoprotein C-IV
ARCN1 archain 1
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
AXIN1 axin 1
BATF basic leucine zipper transcription factor, ATF-like
BCL9 B-cell CLL/lymphoma 9
BIN1 bridging integrator 1
BLM Bloom syndrome, RecQ helicase-like
BMP1 bone morphogenetic protein 1
BMP5 bone morphogenetic protein 5
CA4 carbonic anhydrase IV
CA9 carbonic anhydrase IX
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCIN calicin
CCKAR cholecystokinin A receptor
CCL23 chemokine (C-C motif) ligand 23
CD1A CD1a molecule
CD52 CD52 molecule
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CENPB centromere protein B, 80kDa
CETP cholesteryl ester transfer protein, plasma
CGREF1 cell growth regulator with EF-hand domain 1
CHGA chromogranin A
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
COL4A2 collagen, type IV, alpha 2
COX17 COX17 cytochrome c oxidase copper chaperone
CPT2 carnitine palmitoyltransferase 2
CTF1 cardiotrophin 1
CXCR3 chemokine (C-X-C motif) receptor 3
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DCAF7 DDB1 and CUL4 associated factor 7
DEFB1 defensin, beta 1
DMWD dystrophia myotonica, WD repeat containing
DNASE2 deoxyribonuclease II, lysosomal
DRD5 dopamine receptor D5
DVL1 dishevelled segment polarity protein 1
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EGR1 early growth response 1
EIF5A eukaryotic translation initiation factor 5A
EMC1 ER membrane protein complex subunit 1
EPHA2 EPH receptor A2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
ETV4 ets variant 4
EVX1 even-skipped homeobox 1
FAM189A2 family with sequence similarity 189, member A2
FCGBP Fc fragment of IgG binding protein
FDXR ferredoxin reductase
FGD1 FYVE, RhoGEF and PH domain containing 1
FHL2 four and a half LIM domains 2
FOXO4 forkhead box O4
FSHR follicle stimulating hormone receptor
FZD5 frizzled class receptor 5
GADD45A growth arrest and DNA-damage-inducible, alpha
GALNS galactosamine (N-acetyl)-6-sulfatase
GCHFR GTP cyclohydrolase I feedback regulator
GGT5 gamma-glutamyltransferase 5
GLB1 galactosidase, beta 1
GNL1 guanine nucleotide binding protein-like 1
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GP2 glycoprotein 2 (zymogen granule membrane)
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
GUCA2B guanylate cyclase activator 2B (uroguanylin)
HAGH hydroxyacylglutathione hydrolase
HBA2 hemoglobin, alpha 2
HIST1H3B histone cluster 1, H3b
HK3 hexokinase 3 (white cell)
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXB13 homeobox B13
HOXC5 homeobox C5
HRC histidine rich calcium binding protein
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
HSPA1B heat shock 70kDa protein 1B
HSPG2 heparan sulfate proteoglycan 2
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFITM1 interferon induced transmembrane protein 1
INTS9 integrator complex subunit 9
ITGB1BP1 integrin beta 1 binding protein 1
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KDM5C lysine (K)-specific demethylase 5C
KIAA1549L KIAA1549-like
KIF22 kinesin family member 22
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLF4 Kruppel-like factor 4 (gut)
KLK6 kallikrein-related peptidase 6
KMT2A lysine (K)-specific methyltransferase 2A
KSR1 kinase suppressor of ras 1
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MALL mal, T-cell differentiation protein-like
MARK3 MAP/microtubule affinity-regulating kinase 3
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MAT1A methionine adenosyltransferase I, alpha
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MED12 mediator complex subunit 12
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MKI67 marker of proliferation Ki-67
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MNX1 motor neuron and pancreas homeobox 1
MSLN mesothelin
MSN moesin
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYT1 myelin transcription factor 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NCSTN nicastrin
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NEK3 NIMA-related kinase 3
NFE2 nuclear factor, erythroid 2
NKG7 natural killer cell granule protein 7
NSG1 neuron specific gene family member 1
OPRD1 opioid receptor, delta 1
PAX2 paired box 2
PCDHGA12 protocadherin gamma subfamily A, 12
PCGF2 polycomb group ring finger 2
PCSK7 proprotein convertase subtilisin/kexin type 7
PDE1B phosphodiesterase 1B, calmodulin-dependent
PDE2A phosphodiesterase 2A, cGMP-stimulated
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLK3 polo-like kinase 3
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPP5C protein phosphatase 5, catalytic subunit
PPY pancreatic polypeptide
PRRC2A proline-rich coiled-coil 2A
PTMS parathymosin
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PTS 6-pyruvoyltetrahydropterin synthase
RAB31 RAB31, member RAS oncogene family
RABEPK Rab9 effector protein with kelch motifs
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
RCVRN recoverin
REEP5 receptor accessory protein 5
RGR retinal G protein coupled receptor
RHO rhodopsin
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RRAS related RAS viral (r-ras) oncogene homolog
RXRA retinoid X receptor, alpha
RXRB retinoid X receptor, beta
S100B S100 calcium binding protein B
SCAP SREBF chaperone
SELPLG selectin P ligand
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLN sarcolipin
SMOX spermine oxidase
SMTN smoothelin
SNRPC small nuclear ribonucleoprotein polypeptide C
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STAT5A signal transducer and activator of transcription 5A
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SYN1 synapsin I
TAGLN transgelin
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TFPI2 tissue factor pathway inhibitor 2
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
THY1 Thy-1 cell surface antigen
TK2 thymidine kinase 2, mitochondrial
TRAF1 TNF receptor-associated factor 1
TRIM25 tripartite motif containing 25
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TSC2 tuberous sclerosis 2
TTLL12 tubulin tyrosine ligase-like family member 12
UBXN1 UBX domain protein 1
WNT1 wingless-type MMTV integration site family, member 1
WNT10B wingless-type MMTV integration site family, member 10B
WT1-AS WT1 antisense RNA
ZYX zyxin

decreased expression

Symbol Name
ACAA1 acetyl-CoA acyltransferase 1
ACAA2 acetyl-CoA acyltransferase 2
ACKR3 atypical chemokine receptor 3
ACVR1 activin A receptor, type I
AGER advanced glycosylation end product-specific receptor
AKAP6 A kinase (PRKA) anchor protein 6
ALOX5 arachidonate 5-lipoxygenase
ALPPL2 alkaline phosphatase, placental-like 2
AMBP alpha-1-microglobulin/bikunin precursor
AMHR2 anti-Mullerian hormone receptor, type II
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
AP3B1 adaptor-related protein complex 3, beta 1 subunit
ARNT aryl hydrocarbon receptor nuclear translocator
ASGR2 asialoglycoprotein receptor 2
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
ATF2 activating transcription factor 2
ATF7 activating transcription factor 7
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATR ATR serine/threonine kinase
BAG1 BCL2-associated athanogene
BBC3 BCL2 binding component 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA2 breast cancer 2, early onset
BTG1 B-cell translocation gene 1, anti-proliferative
BTN2A1 butyrophilin, subfamily 2, member A1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAPG capping protein (actin filament), gelsolin-like
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CBLN1 cerebellin 1 precursor
CCL11 chemokine (C-C motif) ligand 11
CCNG2 cyclin G2
CCR9 chemokine (C-C motif) receptor 9
CD19 CD19 molecule
CDKL5 cyclin-dependent kinase-like 5
CFB complement factor B
CHRM1 cholinergic receptor, muscarinic 1
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CLP1 cleavage and polyadenylation factor I subunit 1
COG2 component of oligomeric golgi complex 2
CPA3 carboxypeptidase A3 (mast cell)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CUL7 cullin 7
CXCR4 chemokine (C-X-C motif) receptor 4
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DAZL deleted in azoospermia-like
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EMC2 ER membrane protein complex subunit 2
EML1 echinoderm microtubule associated protein like 1
EPHA1 EPH receptor A1
ERCC4 excision repair cross-complementation group 4
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FLOT2 flotillin 2
FXR2 fragile X mental retardation, autosomal homolog 2
G6PC glucose-6-phosphatase, catalytic subunit
GAB1 GRB2-associated binding protein 1
GAL galanin/GMAP prepropeptide
GALK1 galactokinase 1
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA4 GATA binding protein 4
GCK glucokinase (hexokinase 4)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNS glucosamine (N-acetyl)-6-sulfatase
GPR1 G protein-coupled receptor 1
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
GUCY2C guanylate cyclase 2C
GYS1 glycogen synthase 1 (muscle)
HDAC2 histone deacetylase 2
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HPCA hippocalcin
HPS1 Hermansky-Pudlak syndrome 1
HRG histidine-rich glycoprotein
HRH1 histamine receptor H1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IGF1 insulin-like growth factor 1 (somatomedin C)
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL7R interleukin 7 receptor
ILF3 interleukin enhancer binding factor 3, 90kDa
INHBA inhibin, beta A
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGB6 integrin, beta 6
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KIAA0040 KIAA0040
KIAA0141 KIAA0141
KIF1A kinesin family member 1A
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KLF9 Kruppel-like factor 9
KRT17 keratin 17, type I
KRT5 keratin 5, type II
LAMB1 laminin, beta 1
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LMAN2 lectin, mannose-binding 2
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MATK megakaryocyte-associated tyrosine kinase
MFAP3 microfibrillar-associated protein 3
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MPI mannose phosphate isomerase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MT1F metallothionein 1F
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYL5 myosin, light chain 5, regulatory
MYL9 myosin, light chain 9, regulatory
MYO1C myosin IC
MYO1F myosin IF
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NCKAP1L NCK-associated protein 1-like
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NELL1 NEL-like 1 (chicken)
NKX2-5 NK2 homeobox 5
NNT nicotinamide nucleotide transhydrogenase
NOS1 nitric oxide synthase 1 (neuronal)
NR6A1 nuclear receptor subfamily 6, group A, member 1
NTF4 neurotrophin 4
NTHL1 nth endonuclease III-like 1 (E. coli)
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PARG poly (ADP-ribose) glycohydrolase
PBX2 pre-B-cell leukemia homeobox 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDCD2 programmed cell death 2
PDYN prodynorphin
PEPD peptidase D
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
POU3F1 POU class 3 homeobox 1
PPARA peroxisome proliferator-activated receptor alpha
PPIG peptidylprolyl isomerase G (cyclophilin G)
PRKCQ protein kinase C, theta
PSEN2 presenilin 2
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PUM2 pumilio RNA-binding family member 2
PVALB parvalbumin
RAB9A RAB9A, member RAS oncogene family
RAB9BP1 RAB9B, member RAS oncogene family pseudogene 1
RBMS2 RNA binding motif, single stranded interacting protein 2
RGS16 regulator of G-protein signaling 16
RLBP1 retinaldehyde binding protein 1
RNASE4 ribonuclease, RNase A family, 4
RNASE6 ribonuclease, RNase A family, k6
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RXRG retinoid X receptor, gamma
RYK receptor-like tyrosine kinase
S100A4 S100 calcium binding protein A4
S100G S100 calcium binding protein G
SART3 squamous cell carcinoma antigen recognized by T cells 3
SCAF11 SR-related CTD-associated factor 11
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SPHAR S-phase response (cyclin related)
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPINK1 serine peptidase inhibitor, Kazal type 1
SPRR2C small proline-rich protein 2C (pseudogene)
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SSTR1 somatostatin receptor 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYPL1 synaptophysin-like 1
SYT1 synaptotagmin I
TARBP2 TAR (HIV-1) RNA binding protein 2
TBC1D31 TBC1 domain family, member 31
TFCP2 transcription factor CP2
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TNNT3 troponin T type 3 (skeletal, fast)
TOB2 transducer of ERBB2, 2
TPD52 tumor protein D52
TPM2 tropomyosin 2 (beta)
TPM3 tropomyosin 3
TRH thyrotropin-releasing hormone
TUBA4A tubulin, alpha 4a
TXLNA taxilin alpha
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UMPS uridine monophosphate synthetase
UNG uracil-DNA glycosylase
USP9X ubiquitin specific peptidase 9, X-linked
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VASP vasodilator-stimulated phosphoprotein
WTAP Wilms tumor 1 associated protein
WWOX WW domain containing oxidoreductase
YLPM1 YLP motif containing 1
ZNF133 zinc finger protein 133
ZNF266 zinc finger protein 266
ZNF35 zinc finger protein 35