| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/CYCLIN_D1_UP.V1_UP |
| Similar Terms | |
| Downloads & Tools |
379 genes differentially expressed following the CYCLIN_D1_UP.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABLIM1 | actin binding LIM protein 1 |
| ADRA2A | adrenoceptor alpha 2A |
| ADRA2B | adrenoceptor alpha 2B |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 |
| ANPEP | alanyl (membrane) aminopeptidase |
| APOA1 | apolipoprotein A-I |
| APOC4 | apolipoprotein C-IV |
| ARCN1 | archain 1 |
| ATP4A | ATPase, H+/K+ exchanging, alpha polypeptide |
| AXIN1 | axin 1 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BCL9 | B-cell CLL/lymphoma 9 |
| BIN1 | bridging integrator 1 |
| BLM | Bloom syndrome, RecQ helicase-like |
| BMP1 | bone morphogenetic protein 1 |
| BMP5 | bone morphogenetic protein 5 |
| CA4 | carbonic anhydrase IV |
| CA9 | carbonic anhydrase IX |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCIN | calicin |
| CCKAR | cholecystokinin A receptor |
| CCL23 | chemokine (C-C motif) ligand 23 |
| CD1A | CD1a molecule |
| CD52 | CD52 molecule |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CENPB | centromere protein B, 80kDa |
| CETP | cholesteryl ester transfer protein, plasma |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHGA | chromogranin A |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| COL4A2 | collagen, type IV, alpha 2 |
| COX17 | COX17 cytochrome c oxidase copper chaperone |
| CPT2 | carnitine palmitoyltransferase 2 |
| CTF1 | cardiotrophin 1 |
| CXCR3 | chemokine (C-X-C motif) receptor 3 |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| DCAF7 | DDB1 and CUL4 associated factor 7 |
| DEFB1 | defensin, beta 1 |
| DMWD | dystrophia myotonica, WD repeat containing |
| DNASE2 | deoxyribonuclease II, lysosomal |
| DRD5 | dopamine receptor D5 |
| DVL1 | dishevelled segment polarity protein 1 |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
| EGR1 | early growth response 1 |
| EIF5A | eukaryotic translation initiation factor 5A |
| EMC1 | ER membrane protein complex subunit 1 |
| EPHA2 | EPH receptor A2 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| ETV4 | ets variant 4 |
| EVX1 | even-skipped homeobox 1 |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FCGBP | Fc fragment of IgG binding protein |
| FDXR | ferredoxin reductase |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FHL2 | four and a half LIM domains 2 |
| FOXO4 | forkhead box O4 |
| FSHR | follicle stimulating hormone receptor |
| FZD5 | frizzled class receptor 5 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GALNS | galactosamine (N-acetyl)-6-sulfatase |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GGT5 | gamma-glutamyltransferase 5 |
| GLB1 | galactosidase, beta 1 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GOT1 | glutamic-oxaloacetic transaminase 1, soluble |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GPT | glutamic-pyruvate transaminase (alanine aminotransferase) |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa |
| GUCA2B | guanylate cyclase activator 2B (uroguanylin) |
| HAGH | hydroxyacylglutathione hydrolase |
| HBA2 | hemoglobin, alpha 2 |
| HIST1H3B | histone cluster 1, H3b |
| HK3 | hexokinase 3 (white cell) |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXB13 | homeobox B13 |
| HOXC5 | homeobox C5 |
| HRC | histidine rich calcium binding protein |
| HSD17B10 | hydroxysteroid (17-beta) dehydrogenase 10 |
| HSPA1B | heat shock 70kDa protein 1B |
| HSPG2 | heparan sulfate proteoglycan 2 |
| HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IFITM1 | interferon induced transmembrane protein 1 |
| INTS9 | integrator complex subunit 9 |
| ITGB1BP1 | integrin beta 1 binding protein 1 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA1549L | KIAA1549-like |
| KIF22 | kinesin family member 22 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLK6 | kallikrein-related peptidase 6 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| KSR1 | kinase suppressor of ras 1 |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MALL | mal, T-cell differentiation protein-like |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 |
| MASP1 | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) |
| MAT1A | methionine adenosyltransferase I, alpha |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MED12 | mediator complex subunit 12 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase |
| MKI67 | marker of proliferation Ki-67 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MSLN | mesothelin |
| MSN | moesin |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle |
| MYT1 | myelin transcription factor 1 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NCSTN | nicastrin |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NEK3 | NIMA-related kinase 3 |
| NFE2 | nuclear factor, erythroid 2 |
| NKG7 | natural killer cell granule protein 7 |
| NSG1 | neuron specific gene family member 1 |
| OPRD1 | opioid receptor, delta 1 |
| PAX2 | paired box 2 |
| PCDHGA12 | protocadherin gamma subfamily A, 12 |
| PCGF2 | polycomb group ring finger 2 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDE1B | phosphodiesterase 1B, calmodulin-dependent |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PLK3 | polo-like kinase 3 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PPY | pancreatic polypeptide |
| PRRC2A | proline-rich coiled-coil 2A |
| PTMS | parathymosin |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 |
| PTS | 6-pyruvoyltetrahydropterin synthase |
| RAB31 | RAB31, member RAS oncogene family |
| RABEPK | Rab9 effector protein with kelch motifs |
| RASGRF1 | Ras protein-specific guanine nucleotide-releasing factor 1 |
| RASSF7 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 |
| RCVRN | recoverin |
| REEP5 | receptor accessory protein 5 |
| RGR | retinal G protein coupled receptor |
| RHO | rhodopsin |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| RRAS | related RAS viral (r-ras) oncogene homolog |
| RXRA | retinoid X receptor, alpha |
| RXRB | retinoid X receptor, beta |
| S100B | S100 calcium binding protein B |
| SCAP | SREBF chaperone |
| SELPLG | selectin P ligand |
| SERPINB10 | serpin peptidase inhibitor, clade B (ovalbumin), member 10 |
| SGCA | sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC18A3 | solute carrier family 18 (vesicular acetylcholine transporter), member 3 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SLN | sarcolipin |
| SMOX | spermine oxidase |
| SMTN | smoothelin |
| SNRPC | small nuclear ribonucleoprotein polypeptide C |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| STAT5A | signal transducer and activator of transcription 5A |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| SYN1 | synapsin I |
| TAGLN | transgelin |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TGFB1 | transforming growth factor, beta 1 |
| THBD | thrombomodulin |
| THY1 | Thy-1 cell surface antigen |
| TK2 | thymidine kinase 2, mitochondrial |
| TRAF1 | TNF receptor-associated factor 1 |
| TRIM25 | tripartite motif containing 25 |
| TRPC3 | transient receptor potential cation channel, subfamily C, member 3 |
| TSC2 | tuberous sclerosis 2 |
| TTLL12 | tubulin tyrosine ligase-like family member 12 |
| UBXN1 | UBX domain protein 1 |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| WT1-AS | WT1 antisense RNA |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ACAA1 | acetyl-CoA acyltransferase 1 |
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ACKR3 | atypical chemokine receptor 3 |
| ACVR1 | activin A receptor, type I |
| AGER | advanced glycosylation end product-specific receptor |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| ALOX5 | arachidonate 5-lipoxygenase |
| ALPPL2 | alkaline phosphatase, placental-like 2 |
| AMBP | alpha-1-microglobulin/bikunin precursor |
| AMHR2 | anti-Mullerian hormone receptor, type II |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ASGR2 | asialoglycoprotein receptor 2 |
| ASNA1 | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) |
| ATF2 | activating transcription factor 2 |
| ATF7 | activating transcription factor 7 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A |
| ATR | ATR serine/threonine kinase |
| BAG1 | BCL2-associated athanogene |
| BBC3 | BCL2 binding component 3 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| BRCA2 | breast cancer 2, early onset |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| BTN2A1 | butyrophilin, subfamily 2, member A1 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CAPG | capping protein (actin filament), gelsolin-like |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CBLN1 | cerebellin 1 precursor |
| CCL11 | chemokine (C-C motif) ligand 11 |
| CCNG2 | cyclin G2 |
| CCR9 | chemokine (C-C motif) receptor 9 |
| CD19 | CD19 molecule |
| CDKL5 | cyclin-dependent kinase-like 5 |
| CFB | complement factor B |
| CHRM1 | cholinergic receptor, muscarinic 1 |
| CHRNG | cholinergic receptor, nicotinic, gamma (muscle) |
| CLP1 | cleavage and polyadenylation factor I subunit 1 |
| COG2 | component of oligomeric golgi complex 2 |
| CPA3 | carboxypeptidase A3 (mast cell) |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| CUL7 | cullin 7 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 |
| DAZL | deleted in azoospermia-like |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 |
| EMC2 | ER membrane protein complex subunit 2 |
| EML1 | echinoderm microtubule associated protein like 1 |
| EPHA1 | EPH receptor A1 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FLOT2 | flotillin 2 |
| FXR2 | fragile X mental retardation, autosomal homolog 2 |
| G6PC | glucose-6-phosphatase, catalytic subunit |
| GAB1 | GRB2-associated binding protein 1 |
| GAL | galanin/GMAP prepropeptide |
| GALK1 | galactokinase 1 |
| GATA1 | GATA binding protein 1 (globin transcription factor 1) |
| GATA4 | GATA binding protein 4 |
| GCK | glucokinase (hexokinase 4) |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNS | glucosamine (N-acetyl)-6-sulfatase |
| GPR1 | G protein-coupled receptor 1 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| GUCY2C | guanylate cyclase 2C |
| GYS1 | glycogen synthase 1 (muscle) |
| HDAC2 | histone deacetylase 2 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha |
| HPCA | hippocalcin |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HRG | histidine-rich glycoprotein |
| HRH1 | histamine receptor H1 |
| HTR1A | 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) |
| IGF1 | insulin-like growth factor 1 (somatomedin C) |
| IL17A | interleukin 17A |
| IL1A | interleukin 1, alpha |
| IL7R | interleukin 7 receptor |
| ILF3 | interleukin enhancer binding factor 3, 90kDa |
| INHBA | inhibin, beta A |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITGB6 | integrin, beta 6 |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KIAA0040 | KIAA0040 |
| KIAA0141 | KIAA0141 |
| KIF1A | kinesin family member 1A |
| KIR2DL4 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 |
| KLF9 | Kruppel-like factor 9 |
| KRT17 | keratin 17, type I |
| KRT5 | keratin 5, type II |
| LAMB1 | laminin, beta 1 |
| LILRB4 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 |
| LMAN2 | lectin, mannose-binding 2 |
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MFAP3 | microfibrillar-associated protein 3 |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| MPI | mannose phosphate isomerase |
| MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) |
| MT1F | metallothionein 1F |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult |
| MYL5 | myosin, light chain 5, regulatory |
| MYL9 | myosin, light chain 9, regulatory |
| MYO1C | myosin IC |
| MYO1F | myosin IF |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NCKAP1L | NCK-associated protein 1-like |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
| NELL1 | NEL-like 1 (chicken) |
| NKX2-5 | NK2 homeobox 5 |
| NNT | nicotinamide nucleotide transhydrogenase |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NTF4 | neurotrophin 4 |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PARG | poly (ADP-ribose) glycohydrolase |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PDCD2 | programmed cell death 2 |
| PDYN | prodynorphin |
| PEPD | peptidase D |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| POU3F1 | POU class 3 homeobox 1 |
| PPARA | peroxisome proliferator-activated receptor alpha |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) |
| PRKCQ | protein kinase C, theta |
| PSEN2 | presenilin 2 |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| PUM2 | pumilio RNA-binding family member 2 |
| PVALB | parvalbumin |
| RAB9A | RAB9A, member RAS oncogene family |
| RAB9BP1 | RAB9B, member RAS oncogene family pseudogene 1 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RGS16 | regulator of G-protein signaling 16 |
| RLBP1 | retinaldehyde binding protein 1 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RNASE6 | ribonuclease, RNase A family, k6 |
| ROS1 | ROS proto-oncogene 1 , receptor tyrosine kinase |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| RXRG | retinoid X receptor, gamma |
| RYK | receptor-like tyrosine kinase |
| S100A4 | S100 calcium binding protein A4 |
| S100G | S100 calcium binding protein G |
| SART3 | squamous cell carcinoma antigen recognized by T cells 3 |
| SCAF11 | SR-related CTD-associated factor 11 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa |
| SPHAR | S-phase response (cyclin related) |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPRR2C | small proline-rich protein 2C (pseudogene) |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SSTR1 | somatostatin receptor 1 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SYPL1 | synaptophysin-like 1 |
| SYT1 | synaptotagmin I |
| TARBP2 | TAR (HIV-1) RNA binding protein 2 |
| TBC1D31 | TBC1 domain family, member 31 |
| TFCP2 | transcription factor CP2 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein |
| TNNT3 | troponin T type 3 (skeletal, fast) |
| TOB2 | transducer of ERBB2, 2 |
| TPD52 | tumor protein D52 |
| TPM2 | tropomyosin 2 (beta) |
| TPM3 | tropomyosin 3 |
| TRH | thyrotropin-releasing hormone |
| TUBA4A | tubulin, alpha 4a |
| TXLNA | taxilin alpha |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| UMPS | uridine monophosphate synthetase |
| UNG | uracil-DNA glycosylase |
| USP9X | ubiquitin specific peptidase 9, X-linked |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VASP | vasodilator-stimulated phosphoprotein |
| WTAP | Wilms tumor 1 associated protein |
| WWOX | WW domain containing oxidoreductase |
| YLPM1 | YLP motif containing 1 |
| ZNF133 | zinc finger protein 133 |
| ZNF266 | zinc finger protein 266 |
| ZNF35 | zinc finger protein 35 |
