| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cytochrome P450, family 1, subfamily A, polypeptide 1|This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1543) |
| External Link | https://ncbi.nlm.nih.gov/gene/1543 |
| Similar Terms | |
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476 genes differentially expressed following the CYP1A1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TLCD3A | TLC domain containing 3A | 0.0180462 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.0135939 |
| HOPX | HOP homeobox | 0.0128488 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.0126647 |
| GSTP1 | glutathione S-transferase pi 1 | 0.0113617 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0113132 |
| TOX | thymocyte selection-associated high mobility group box | 0.0108486 |
| GNAS | GNAS complex locus | 0.010199 |
| ABHD4 | abhydrolase domain containing 4 | 0.00997316 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00995192 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00994299 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00982642 |
| TMEM45A | transmembrane protein 45A | 0.00957414 |
| MXRA5 | matrix-remodelling associated 5 | 0.00937953 |
| THY1 | Thy-1 cell surface antigen | 0.00896138 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00893508 |
| CTSH | cathepsin H | 0.00888248 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.00874152 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.00864435 |
| SIRT3 | sirtuin 3 | 0.00863012 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00856001 |
| KIF2C | kinesin family member 2C | 0.00844419 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00840494 |
| CDC20 | cell division cycle 20 | 0.00839241 |
| CFI | complement factor I | 0.0083459 |
| KRT17 | keratin 17, type I | 0.00830947 |
| GPM6B | glycoprotein M6B | 0.00830814 |
| PCNA | proliferating cell nuclear antigen | 0.00823875 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00820353 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00819924 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.00818292 |
| MARCKSL1 | MARCKS-like 1 | 0.0081421 |
| CTSV | cathepsin V | 0.00809007 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00808884 |
| ADD3 | adducin 3 (gamma) | 0.00808801 |
| MSLN | mesothelin | 0.00808192 |
| KRT7 | keratin 7, type II | 0.00807056 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00801534 |
| PDGFD | platelet derived growth factor D | 0.0078928 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00786735 |
| LTF | lactotransferrin | 0.00780567 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.007799 |
| IL32 | interleukin 32 | 0.00778295 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00775172 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00765907 |
| S100A2 | S100 calcium binding protein A2 | 0.00764188 |
| PRODH | proline dehydrogenase (oxidase) 1 | 0.00761581 |
| CTSC | cathepsin C | 0.00754498 |
| TSPAN8 | tetraspanin 8 | 0.00751371 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00746495 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00740712 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 0.0074014 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00740117 |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | 0.00738576 |
| SDC1 | syndecan 1 | 0.0073675 |
| SLC12A8 | solute carrier family 12, member 8 | 0.00734255 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.00727002 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.00724728 |
| MMP7 | matrix metallopeptidase 7 | 0.00723779 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00721976 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00721285 |
| RPS5 | ribosomal protein S5 | 0.00720983 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.00715769 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | 0.00713611 |
| IRS2 | insulin receptor substrate 2 | 0.00711591 |
| FSTL1 | follistatin-like 1 | 0.00709578 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | 0.00708559 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.00708232 |
| BMP2 | bone morphogenetic protein 2 | 0.00705974 |
| SPRR1B | small proline-rich protein 1B | 0.00701459 |
| TNNC1 | troponin C type 1 (slow) | 0.00695502 |
| SYNDIG1 | synapse differentiation inducing 1 | 0.00688046 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00687245 |
| PRDX2 | peroxiredoxin 2 | 0.00685875 |
| LYZ | lysozyme | 0.00685647 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00684569 |
| CD99 | CD99 molecule | 0.00683622 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00683295 |
| CA12 | carbonic anhydrase XII | 0.00680566 |
| FAM162A | family with sequence similarity 162, member A | 0.00679256 |
| DCLK1 | doublecortin-like kinase 1 | 0.00674575 |
| INAVA | innate immunity activator | 0.0067401 |
| GPC3 | glypican 3 | 0.006707 |
| ZNF395 | zinc finger protein 395 | 0.00670663 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.00669534 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | 0.0066604 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00659609 |
| TYMS | thymidylate synthetase | 0.0065595 |
| KRT6A | keratin 6A, type II | 0.00655306 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00654969 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.00652051 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.0065086 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00647292 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00646056 |
| SFTPB | surfactant protein B | 0.00646035 |
| KRT16 | keratin 16, type I | 0.00645974 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00644263 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | 0.00643236 |
| COL5A2 | collagen, type V, alpha 2 | 0.00642851 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00640805 |
| AKR1A1 | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 0.00638313 |
| RRAGA | Ras-related GTP binding A | 0.00637728 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00636261 |
| CD200 | CD200 molecule | 0.00635066 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.00634163 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00632576 |
| DAD1 | defender against cell death 1 | 0.0063216 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | 0.00631919 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.0063028 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.00630146 |
| GOLGA8H | golgin A8 family, member H | 0.00630014 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00629772 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.00626053 |
| GSTT1 | glutathione S-transferase theta 1 | 0.00625894 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 | 0.00625738 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.00623226 |
| LRRC17 | leucine rich repeat containing 17 | 0.00623004 |
| NFIB | nuclear factor I/B | 0.00622934 |
| SNX5 | sorting nexin 5 | 0.00622483 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00616039 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0061559 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00614019 |
| FBLN1 | fibulin 1 | 0.00612604 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00612264 |
| TLE4 | transducin-like enhancer of split 4 | 0.00611506 |
| CLIC3 | chloride intracellular channel 3 | 0.00611373 |
| EREG | epiregulin | 0.00611135 |
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle | 0.00609836 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00609696 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 0.00606876 |
| RGS13 | regulator of G-protein signaling 13 | 0.00605902 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.00600568 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00600048 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.0059937 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00599192 |
| SCEL | sciellin | 0.00598121 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00596947 |
| RNASET2 | ribonuclease T2 | 0.00595942 |
| ACKR3 | atypical chemokine receptor 3 | 0.00595677 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00595401 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00595384 |
| OLFML2B | olfactomedin-like 2B | 0.00594815 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0059451 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00593419 |
| BEX1 | brain expressed, X-linked 1 | 0.00592562 |
| PTCH1 | patched 1 | 0.00592244 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00591294 |
| C1R | complement component 1, r subcomponent | 0.00590249 |
| COL5A1 | collagen, type V, alpha 1 | 0.00588869 |
| ITM2A | integral membrane protein 2A | 0.00588808 |
| RAB25 | RAB25, member RAS oncogene family | 0.00585816 |
| DSP | desmoplakin | 0.00584549 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase | 0.00584474 |
| PLLP | plasmolipin | 0.00584432 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00584124 |
| SORD | sorbitol dehydrogenase | 0.00583766 |
| GPX1 | glutathione peroxidase 1 | 0.0058375 |
| MRPL19 | mitochondrial ribosomal protein L19 | 0.0058353 |
| A2M | alpha-2-macroglobulin | 0.00583219 |
| MAGT1 | magnesium transporter 1 | 0.00580565 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.00579072 |
| L1CAM | L1 cell adhesion molecule | 0.0057781 |
| MYO6 | myosin VI | 0.00576683 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | 0.0057594 |
| STK39 | serine threonine kinase 39 | 0.00575071 |
| CHPT1 | choline phosphotransferase 1 | 0.00575026 |
| PPL | periplakin | 0.00574991 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00572911 |
| EHBP1 | EH domain binding protein 1 | 0.00572843 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00571781 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00571069 |
| TP53I3 | tumor protein p53 inducible protein 3 | 0.00569943 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00568224 |
| TBX3 | T-box 3 | 0.00565982 |
| NDUFC1 | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa | 0.00563806 |
| TRAM1 | translocation associated membrane protein 1 | 0.00563603 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.00562941 |
| GAS2 | growth arrest-specific 2 | 0.00562426 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0056219 |
| NKX2-1 | NK2 homeobox 1 | 0.00562036 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.00561594 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.00561318 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00558329 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.00558291 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00557813 |
| PLS3 | plastin 3 | 0.00556914 |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 | 0.00556016 |
| METTL17 | methyltransferase like 17 | 0.00555598 |
| ACSF2 | acyl-CoA synthetase family member 2 | 0.00554158 |
| KRT6B | keratin 6B, type II | 0.00553749 |
| CSTA | cystatin A (stefin A) | 0.00552154 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.0055166 |
| GCH1 | GTP cyclohydrolase 1 | 0.00551187 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00550965 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.00550422 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.0054926 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00546773 |
| MPZL2 | myelin protein zero-like 2 | 0.00545584 |
| LOXL2 | lysyl oxidase-like 2 | 0.00545497 |
| PITX1 | paired-like homeodomain 1 | 0.00543912 |
| THBS2 | thrombospondin 2 | 0.00543809 |
| COL11A1 | collagen, type XI, alpha 1 | 0.00542949 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00542122 |
| IGSF1 | immunoglobulin superfamily, member 1 | 0.00542116 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 0.00539363 |
| CLIC5 | chloride intracellular channel 5 | 0.00539068 |
| MYBPC1 | myosin binding protein C, slow type | 0.00539021 |
| LY86 | lymphocyte antigen 86 | 0.00538178 |
| SFTPA2 | surfactant protein A2 | 0.0053719 |
| CAPN3 | calpain 3, (p94) | 0.0053715 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00535576 |
| TRIM29 | tripartite motif containing 29 | 0.00535439 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta | 0.0053302 |
| MAGED1 | melanoma antigen family D1 | 0.00532685 |
| LAMB3 | laminin, beta 3 | 0.00531434 |
| PEG10 | paternally expressed 10 | 0.00531376 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | 0.00530783 |
| MTMR11 | myotubularin related protein 11 | 0.00530617 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | 0.00528845 |
| ANXA5 | annexin A5 | 0.00527856 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00526548 |
| HDAC4 | histone deacetylase 4 | 0.00525727 |
| DGLUCY | D-glutamate cyclase | 0.00523466 |
| SLBP | stem-loop binding protein | 0.005231 |
| SHTN1 | shootin 1 | 0.00523072 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.00521122 |
| NOTCH2 | notch 2 | 0.00520952 |
| OGN | osteoglycin | 0.00519533 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.0051929 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00518275 |
| CLEC7A | C-type lectin domain family 7, member A | 0.00518219 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00516703 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00516549 |
| PARP2 | poly (ADP-ribose) polymerase 2 | 0.00515625 |
| H2AX | H2A.X variant histone | 0.00515542 |
| KRT10 | keratin 10, type I | 0.00514326 |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 | 0.00513207 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00511997 |
| MFSD10 | major facilitator superfamily domain containing 10 | 0.00511546 |
| NDRG1 | N-myc downstream regulated 1 | 0.00510337 |
| MCM4 | minichromosome maintenance complex component 4 | 0.00510151 |
| FGG | fibrinogen gamma chain | 0.00508856 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.00508664 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RB1 | retinoblastoma 1 | -0.0170687 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0143462 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0121355 |
| CA2 | carbonic anhydrase II | -0.0119269 |
| LCN2 | lipocalin 2 | -0.01153 |
| CHP1 | calcineurin-like EF-hand protein 1 | -0.0112589 |
| MX1 | MX dynamin-like GTPase 1 | -0.0109478 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.0109111 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0108685 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0105889 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0105286 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0102499 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.0102055 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0100999 |
| STMN2 | stathmin 2 | -0.00967951 |
| RELN | reelin | -0.00949369 |
| DUSP5 | dual specificity phosphatase 5 | -0.00945378 |
| C1ORF115 | chromosome 1 open reading frame 115 | -0.00933342 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00923703 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00921294 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00888385 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00876199 |
| APOD | apolipoprotein D | -0.00874984 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00872884 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00854714 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00837178 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) | -0.00836828 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0082731 |
| MT1F | metallothionein 1F | -0.00826478 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00824234 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0082294 |
| MT1M | metallothionein 1M | -0.0082029 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | -0.00814539 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00807111 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00804413 |
| SYT1 | synaptotagmin I | -0.00803929 |
| G0S2 | G0/G1 switch 2 | -0.00801548 |
| IFI44 | interferon-induced protein 44 | -0.00797047 |
| STK10 | serine/threonine kinase 10 | -0.00794928 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00792977 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00787575 |
| TSC22D1 | TSC22 domain family, member 1 | -0.00781818 |
| CCN2 | cellular communication network factor 2 | -0.00776222 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00773819 |
| CD9 | CD9 molecule | -0.00769343 |
| INHBA | inhibin, beta A | -0.0076245 |
| MT1G | metallothionein 1G | -0.00762141 |
| IFI44L | interferon-induced protein 44-like | -0.00761427 |
| MELK | maternal embryonic leucine zipper kinase | -0.00759973 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | -0.00758543 |
| CRYM | crystallin, mu | -0.00757431 |
| TSPAN12 | tetraspanin 12 | -0.00753728 |
| MT1X | metallothionein 1X | -0.00752848 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | -0.007491 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00747067 |
| NEFH | neurofilament, heavy polypeptide | -0.00746392 |
| SCARB2 | scavenger receptor class B, member 2 | -0.00732931 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | -0.00732815 |
| MSMB | microseminoprotein, beta- | -0.00732794 |
| MT1E | metallothionein 1E | -0.00730409 |
| TPBG | trophoblast glycoprotein | -0.00727651 |
| RTN2 | reticulon 2 | -0.0072592 |
| CNN1 | calponin 1, basic, smooth muscle | -0.00725528 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.00717612 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00716548 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00715675 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.0071375 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | -0.00713658 |
| HMP19 | HMP19 protein | -0.00709071 |
| INA | internexin neuronal intermediate filament protein, alpha | -0.00707319 |
| PYCARD | PYD and CARD domain containing | -0.00706137 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00704846 |
| MYO1B | myosin IB | -0.00701955 |
| PROM1 | prominin 1 | -0.00695287 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00690356 |
| RPA3 | replication protein A3, 14kDa | -0.0068628 |
| TFRC | transferrin receptor | -0.00685698 |
| NOTCH1 | notch 1 | -0.00684271 |
| TGFB1 | transforming growth factor, beta 1 | -0.00683294 |
| RIDA | reactive intermediate imine deaminase A homolog | -0.00682638 |
| RGCC | regulator of cell cycle | -0.00679334 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00675004 |
| TSPYL5 | TSPY-like 5 | -0.00673717 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00673331 |
| PCLAF | PCNA clamp associated factor | -0.00672125 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00671074 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0066279 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00660352 |
| FZD6 | frizzled class receptor 6 | -0.0065721 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00657196 |
| CANT1 | calcium activated nucleotidase 1 | -0.0065525 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00654953 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.00651993 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00651755 |
| SYNM | synemin, intermediate filament protein | -0.00647018 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 | -0.00644934 |
| SNX10 | sorting nexin 10 | -0.00644793 |
| CDK17 | cyclin-dependent kinase 17 | -0.00643799 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00643084 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00642627 |
| ARL4A | ADP-ribosylation factor-like 4A | -0.00640397 |
| MRPL13 | mitochondrial ribosomal protein L13 | -0.00639504 |
| KAT2B | K(lysine) acetyltransferase 2B | -0.00638994 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00637208 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00637115 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00635412 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.00635089 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00634341 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.00633174 |
| HIST1H2AE | histone cluster 1, H2ae | -0.00632776 |
| MOK | MOK protein kinase | -0.00627656 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.00623545 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00622886 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.00618774 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 | -0.00617928 |
| HOMER3 | homer scaffolding protein 3 | -0.00616048 |
| TPM2 | tropomyosin 2 (beta) | -0.00613131 |
| GLRX2 | glutaredoxin 2 | -0.00612457 |
| ZIC1 | Zic family member 1 | -0.00611362 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00610732 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | -0.00610315 |
| LY96 | lymphocyte antigen 96 | -0.00608041 |
| POSTN | periostin, osteoblast specific factor | -0.0060797 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00603588 |
| ATP6AP1 | ATPase, H+ transporting, lysosomal accessory protein 1 | -0.00602593 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.00600652 |
| GSN | gelsolin | -0.00598626 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00597672 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.00597143 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00597106 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.00596641 |
| TGM2 | transglutaminase 2 | -0.00595541 |
| FOXD1 | forkhead box D1 | -0.00595195 |
| NRIP3 | nuclear receptor interacting protein 3 | -0.00588597 |
| MMP12 | matrix metallopeptidase 12 | -0.00582876 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.00581617 |
| HMOX1 | heme oxygenase 1 | -0.00581063 |
| EDN1 | endothelin 1 | -0.00580901 |
| TPM4 | tropomyosin 4 | -0.00576039 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00575694 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.00575088 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00574248 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | -0.00573746 |
| SVIL | supervillin | -0.00573188 |
| KDM5A | lysine (K)-specific demethylase 5A | -0.00569527 |
| USP3 | ubiquitin specific peptidase 3 | -0.00569064 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.00568983 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00568529 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.00568456 |
| OAT | ornithine aminotransferase | -0.00567368 |
| SNAI2 | snail family zinc finger 2 | -0.0056512 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00564369 |
| ACP2 | acid phosphatase 2, lysosomal | -0.0056281 |
| TAGLN | transgelin | -0.00562534 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00560452 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00557702 |
| WIF1 | WNT inhibitory factor 1 | -0.00556114 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00555734 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00555525 |
| KRT23 | keratin 23, type I | -0.005551 |
| AMOTL2 | angiomotin like 2 | -0.00554283 |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 | -0.0055428 |
| RUBCN | rubicon autophagy regulator | -0.00553038 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00552841 |
| SATB2 | SATB homeobox 2 | -0.00551415 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00551278 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.00549744 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.00549427 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | -0.00548484 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00547173 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) | -0.00546921 |
| SPEN | spen family transcriptional repressor | -0.00545902 |
| FOLR1 | folate receptor 1 (adult) | -0.00545829 |
| SMAD3 | SMAD family member 3 | -0.00545072 |
| HPX | hemopexin | -0.00543878 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.00543666 |
| PODXL | podocalyxin-like | -0.00540801 |
| STK26 | serine/threonine protein kinase 26 | -0.00540204 |
| KCTD5 | potassium channel tetramerization domain containing 5 | -0.00540183 |
| BGN | biglycan | -0.0054007 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.00538434 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00537512 |
| NPTX1 | neuronal pentraxin I | -0.00537469 |
| FNDC3A | fibronectin type III domain containing 3A | -0.00537411 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00536703 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.00535533 |
| TFR2 | transferrin receptor 2 | -0.00534414 |
| CYTIP | cytohesin 1 interacting protein | -0.00533323 |
| IRF9 | interferon regulatory factor 9 | -0.00531803 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00530977 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00530537 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.00530082 |
| RND3 | Rho family GTPase 3 | -0.00529654 |
| TRIB3 | tribbles pseudokinase 3 | -0.00528976 |
| IQSEC1 | IQ motif and Sec7 domain 1 | -0.00528435 |
| PTPRC | protein tyrosine phosphatase, receptor type, C | -0.00527014 |
| AK1 | adenylate kinase 1 | -0.00526843 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | -0.00525096 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 | -0.00523574 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain | -0.00523455 |
| KRT19 | keratin 19, type I | -0.0052343 |
| TAGLN3 | transgelin 3 | -0.00522905 |
| TGOLN2 | trans-golgi network protein 2 | -0.00522876 |
| CCNA2 | cyclin A2 | -0.0052241 |
| CFB | complement factor B | -0.00521595 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00521439 |
| HAT1 | histone acetyltransferase 1 | -0.0052074 |
| EDNRB | endothelin receptor type B | -0.00519801 |
| FOXC1 | forkhead box C1 | -0.00519062 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.00518483 |
| PKP2 | plakophilin 2 | -0.00517434 |
| ZBTB16 | zinc finger and BTB domain containing 16 | -0.0051674 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.00516671 |
| BEX4 | brain expressed, X-linked 4 | -0.00516646 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.00515756 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00515453 |
| CHGB | chromogranin B | -0.00515097 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | -0.00514298 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00512399 |
| TCF21 | transcription factor 21 | -0.00511771 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00511274 |
| SRGN | serglycin | -0.00510698 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | -0.00510548 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00509649 |
| MGLL | monoglyceride lipase | -0.00509215 |
| EMP1 | epithelial membrane protein 1 | -0.00508641 |
| CBS | cystathionine-beta-synthase | -0.00507657 |
| CALML4 | calmodulin-like 4 | -0.00505638 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00505095 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00504983 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.00504746 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -0.00504547 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.00504419 |
