| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cytochrome P450, family 2, subfamily C, polypeptide 19|This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1557) |
| External Link | https://ncbi.nlm.nih.gov/gene/1557 |
| Similar Terms | |
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499 genes differentially expressed following the CYP2C19 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0217586 |
| MAP7 | microtubule-associated protein 7 | 0.016977 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.016852 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0149822 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.0144432 |
| S100A8 | S100 calcium binding protein A8 | 0.0142082 |
| HOPX | HOP homeobox | 0.0137492 |
| SELL | selectin L | 0.0136971 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0130251 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.0130038 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0124487 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.0124365 |
| S100A9 | S100 calcium binding protein A9 | 0.0124217 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.0124183 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.0119817 |
| STOM | stomatin | 0.0118415 |
| IL32 | interleukin 32 | 0.0116893 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.011619 |
| LTF | lactotransferrin | 0.0115598 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.0115132 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 0.0114026 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0113269 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.0109384 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0108747 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0108177 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0107697 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.0106542 |
| CTSS | cathepsin S | 0.0105812 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.0105663 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.010508 |
| IFI44L | interferon-induced protein 44-like | 0.0105066 |
| COG7 | component of oligomeric golgi complex 7 | 0.0104786 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.0103716 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.0101589 |
| TRIM22 | tripartite motif containing 22 | 0.0100137 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00995338 |
| GPR171 | G protein-coupled receptor 171 | 0.00989017 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00984486 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00982351 |
| AMACR | alpha-methylacyl-CoA racemase | 0.00981988 |
| TPD52L1 | tumor protein D52-like 1 | 0.00976491 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00975732 |
| IL2RG | interleukin 2 receptor, gamma | 0.00975499 |
| LY75 | lymphocyte antigen 75 | 0.0097419 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00973759 |
| TARP | TCR gamma alternate reading frame protein | 0.00970158 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00963678 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | 0.00961384 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00957409 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00957283 |
| S100A7 | S100 calcium binding protein A7 | 0.00956194 |
| ATF3 | activating transcription factor 3 | 0.0095351 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00941848 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00939379 |
| IL7R | interleukin 7 receptor | 0.00938359 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00930477 |
| BCL2A1 | BCL2-related protein A1 | 0.00928098 |
| TFEC | transcription factor EC | 0.00927921 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00927908 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00927602 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00923539 |
| FGF13 | fibroblast growth factor 13 | 0.00921672 |
| CST7 | cystatin F (leukocystatin) | 0.00913143 |
| GIMAP4 | GTPase, IMAP family member 4 | 0.00912839 |
| MT1G | metallothionein 1G | 0.00912232 |
| ABLIM1 | actin binding LIM protein 1 | 0.00910943 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00910218 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00904736 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00901675 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00888232 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | 0.00886154 |
| SP110 | SP110 nuclear body protein | 0.00886055 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00881277 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00880676 |
| LXN | latexin | 0.00877891 |
| ACE2 | angiotensin I converting enzyme 2 | 0.0087738 |
| PLSCR1 | phospholipid scramblase 1 | 0.00873454 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00873054 |
| COG5 | component of oligomeric golgi complex 5 | 0.0087253 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.00871183 |
| SRGN | serglycin | 0.00867643 |
| AREG | amphiregulin | 0.00864174 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00860733 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00857279 |
| SPRR3 | small proline-rich protein 3 | 0.00855057 |
| CHPT1 | choline phosphotransferase 1 | 0.00853925 |
| ANXA1 | annexin A1 | 0.00850823 |
| C1ORF115 | chromosome 1 open reading frame 115 | 0.00846191 |
| KRT14 | keratin 14, type I | 0.00843883 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.00843845 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00842274 |
| GPM6B | glycoprotein M6B | 0.00842205 |
| TSPAN13 | tetraspanin 13 | 0.00831375 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00827597 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00826466 |
| MRTFB | myocardin related transcription factor B | 0.00826075 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.00822272 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00820131 |
| SPRR1B | small proline-rich protein 1B | 0.00816173 |
| ATP5PD | ATP synthase peripheral stalk subunit d | 0.00814525 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00813701 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | 0.0081267 |
| ITK | IL2-inducible T-cell kinase | 0.0081132 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00810588 |
| CFDP1 | craniofacial development protein 1 | 0.00806191 |
| HBB | hemoglobin, beta | 0.00803602 |
| S100A10 | S100 calcium binding protein A10 | 0.00802485 |
| CD69 | CD69 molecule | 0.00801723 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00799992 |
| MYO1C | myosin IC | 0.0079803 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.00795632 |
| IRF7 | interferon regulatory factor 7 | 0.0079416 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 0.00792125 |
| GSTO1 | glutathione S-transferase omega 1 | 0.00786939 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00786523 |
| BFAR | bifunctional apoptosis regulator | 0.00785836 |
| MT1X | metallothionein 1X | 0.00784762 |
| HSBP1 | heat shock factor binding protein 1 | 0.00783253 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 | 0.0078091 |
| HMOX2 | heme oxygenase 2 | 0.00779624 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.00776089 |
| AGTR1 | angiotensin II receptor, type 1 | 0.00775704 |
| NRN1 | neuritin 1 | 0.00774417 |
| DAXX | death-domain associated protein | 0.00771704 |
| MVP | major vault protein | 0.00770889 |
| MREG | melanoregulin | 0.0076989 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | 0.00757568 |
| CLDN8 | claudin 8 | 0.00757549 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.00757459 |
| OPN3 | opsin 3 | 0.00756867 |
| COMT | catechol-O-methyltransferase | 0.0075634 |
| PHF11 | PHD finger protein 11 | 0.00755584 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00753747 |
| MGST3 | microsomal glutathione S-transferase 3 | 0.00753182 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00752445 |
| AVPI1 | arginine vasopressin-induced 1 | 0.00752419 |
| OPTN | optineurin | 0.00752259 |
| ADD3 | adducin 3 (gamma) | 0.00750931 |
| BTN3A2 | butyrophilin, subfamily 3, member A2 | 0.00750552 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00749428 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00749167 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.00748285 |
| XIC | X chromosome inactivation center | 0.00744629 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00743949 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00743418 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.0074309 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | 0.00742861 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 | 0.00741946 |
| WASHC4 | WASH complex subunit 4 | 0.00741869 |
| IL6ST | interleukin 6 signal transducer | 0.00741135 |
| MRPL40 | mitochondrial ribosomal protein L40 | 0.00740693 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00740611 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00739872 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.00738695 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00736125 |
| TLE4 | transducin-like enhancer of split 4 | 0.0073516 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00734093 |
| MPHOSPH8 | M-phase phosphoprotein 8 | 0.00733581 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00731825 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00731589 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00725161 |
| TMEM59 | transmembrane protein 59 | 0.00723827 |
| TRIM38 | tripartite motif containing 38 | 0.00721373 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.00718496 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | 0.00718448 |
| IRF6 | interferon regulatory factor 6 | 0.00717593 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00717173 |
| CA2 | carbonic anhydrase II | 0.00716127 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00715881 |
| SCRG1 | stimulator of chondrogenesis 1 | 0.00714426 |
| HEXB | hexosaminidase B (beta polypeptide) | 0.00710545 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00707964 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | 0.0070795 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.00707582 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | 0.0070758 |
| KRT5 | keratin 5, type II | 0.00707386 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00706363 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00706017 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | 0.00704816 |
| USP18 | ubiquitin specific peptidase 18 | 0.00704405 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.00703588 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.00701718 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | 0.00699585 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.0069958 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | 0.0069924 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.00696057 |
| SMAGP | small cell adhesion glycoprotein | 0.00695996 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00694107 |
| APOL2 | apolipoprotein L, 2 | 0.00694076 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00693227 |
| PROM1 | prominin 1 | 0.00693091 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00691184 |
| KRT17 | keratin 17, type I | 0.00689871 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.00689763 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00688922 |
| MT1M | metallothionein 1M | 0.00688314 |
| MT1E | metallothionein 1E | 0.00688231 |
| CLCA2 | chloride channel accessory 2 | 0.00687815 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00687218 |
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.00686798 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00682178 |
| APOD | apolipoprotein D | 0.00679106 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00679064 |
| CCDC28A | coiled-coil domain containing 28A | 0.00678039 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.00677859 |
| KRT6A | keratin 6A, type II | 0.00677304 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | 0.00674163 |
| TPST2 | tyrosylprotein sulfotransferase 2 | 0.00672875 |
| MALL | mal, T-cell differentiation protein-like | 0.00672582 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00671708 |
| ETHE1 | ethylmalonic encephalopathy 1 | 0.00671431 |
| TMPRSS2 | transmembrane protease, serine 2 | 0.00671067 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00670861 |
| PON2 | paraoxonase 2 | 0.00670653 |
| ECM1 | extracellular matrix protein 1 | 0.00669124 |
| RBM34 | RNA binding motif protein 34 | 0.00667902 |
| TMEM140 | transmembrane protein 140 | 0.00666603 |
| RBKS | ribokinase | 0.00666202 |
| CD48 | CD48 molecule | 0.00665572 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00664026 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.0066295 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00662734 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00661957 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00661713 |
| ANXA3 | annexin A3 | 0.00661699 |
| ELOB | elongin B | 0.00660991 |
| TBC1D4 | TBC1 domain family, member 4 | 0.0066094 |
| EIF2D | eukaryotic translation initiation factor 2D | 0.00660711 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00660475 |
| ZNF267 | zinc finger protein 267 | 0.00659716 |
| PRR15L | proline rich 15-like | 0.00659663 |
| NMT2 | N-myristoyltransferase 2 | 0.00659366 |
| GLUD2 | glutamate dehydrogenase 2 | 0.00658966 |
| TJP2 | tight junction protein 2 | 0.00657659 |
| MIA | melanoma inhibitory activity | 0.00657361 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 0.00656355 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00653681 |
| FGFR4 | fibroblast growth factor receptor 4 | 0.00650596 |
| ATG5 | autophagy related 5 | 0.0065041 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00649975 |
| EPCAM | epithelial cell adhesion molecule | 0.00649945 |
| PRKCQ | protein kinase C, theta | 0.00649058 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.00648272 |
| A2M | alpha-2-macroglobulin | 0.00648178 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00648103 |
| NNMT | nicotinamide N-methyltransferase | 0.00645093 |
| CRYL1 | crystallin, lambda 1 | 0.00642818 |
| LCMT1 | leucine carboxyl methyltransferase 1 | 0.00642018 |
| CNIH1 | cornichon family AMPA receptor auxiliary protein 1 | 0.00641401 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00641271 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXLNA | taxilin alpha | -0.0167941 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0144166 |
| ASS1 | argininosuccinate synthase 1 | -0.0123869 |
| RTN2 | reticulon 2 | -0.0120248 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0118398 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.0112975 |
| MXRA5 | matrix-remodelling associated 5 | -0.011081 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.0109423 |
| INSR | insulin receptor | -0.0107529 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.0106614 |
| KRT19 | keratin 19, type I | -0.0104838 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.0102391 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0100571 |
| C9ORF3 | chromosome 9 open reading frame 3 | -0.010045 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00989135 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00942944 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00941786 |
| PCP4 | Purkinje cell protein 4 | -0.00930428 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00929402 |
| RTN3 | reticulon 3 | -0.00923923 |
| FST | follistatin | -0.00921789 |
| CALCA | calcitonin-related polypeptide alpha | -0.00918791 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00915306 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00909616 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.00899804 |
| NLGN4X | neuroligin 4, X-linked | -0.00892595 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | -0.00873988 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.00865468 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.00849564 |
| STC1 | stanniocalcin 1 | -0.00846259 |
| COL9A2 | collagen, type IX, alpha 2 | -0.00844302 |
| THBS4 | thrombospondin 4 | -0.00840783 |
| FEN1 | flap structure-specific endonuclease 1 | -0.00840396 |
| PEG3 | paternally expressed 3 | -0.0084038 |
| ELN | elastin | -0.00831984 |
| HOXD1 | homeobox D1 | -0.00829215 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00827888 |
| NVL | nuclear VCP-like | -0.00818124 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00815719 |
| SRSF6 | serine/arginine-rich splicing factor 6 | -0.00814286 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | -0.00808742 |
| KRT7 | keratin 7, type II | -0.00806775 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00805905 |
| RXRA | retinoid X receptor, alpha | -0.00799566 |
| TBL1X | transducin (beta)-like 1X-linked | -0.00799196 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.00798485 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00798169 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | -0.00794296 |
| PNN | pinin, desmosome associated protein | -0.0079054 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00788769 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00788061 |
| PWWP3A | PWWP domain containing 3A, DNA repair factor | -0.00786551 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.00786394 |
| PTN | pleiotrophin | -0.00780267 |
| AEBP1 | AE binding protein 1 | -0.0077889 |
| ANGPTL2 | angiopoietin-like 2 | -0.00775796 |
| MB | myoglobin | -0.00774777 |
| FLNC | filamin C, gamma | -0.00757186 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.00753749 |
| SCG5 | secretogranin V | -0.00753018 |
| KIF1A | kinesin family member 1A | -0.00750894 |
| HIP1 | huntingtin interacting protein 1 | -0.00748742 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.00747822 |
| CDC20 | cell division cycle 20 | -0.00747302 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | -0.00747118 |
| CTSZ | cathepsin Z | -0.00746271 |
| CERK | ceramide kinase | -0.00745363 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | -0.00745322 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.00743884 |
| OLFM1 | olfactomedin 1 | -0.00743621 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00741698 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00739905 |
| GOLGA8A | golgin A8 family, member A | -0.00739663 |
| MAB21L1 | mab-21-like 1 (C. elegans) | -0.00738814 |
| CHGB | chromogranin B | -0.00738142 |
| ZNF423 | zinc finger protein 423 | -0.007358 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.0073432 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | -0.00732239 |
| MXRA8 | matrix-remodelling associated 8 | -0.00730156 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00729966 |
| MEST | mesoderm specific transcript | -0.0072899 |
| KIAA0232 | KIAA0232 | -0.00728926 |
| MMP1 | matrix metallopeptidase 1 | -0.00727466 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00727077 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00725965 |
| LOXL1 | lysyl oxidase-like 1 | -0.00724481 |
| CCNL2 | cyclin L2 | -0.00723257 |
| FRZB | frizzled-related protein | -0.00723155 |
| NID2 | nidogen 2 (osteonidogen) | -0.00713868 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.00712795 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00710923 |
| PDLIM3 | PDZ and LIM domain 3 | -0.0070958 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | -0.00708483 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | -0.00707602 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.00706251 |
| CREB1 | cAMP responsive element binding protein 1 | -0.00705197 |
| COL1A2 | collagen, type I, alpha 2 | -0.00702479 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00700202 |
| KCTD14 | potassium channel tetramerization domain containing 14 | -0.00699093 |
| CLCN4 | chloride channel, voltage-sensitive 4 | -0.00697939 |
| MATN2 | matrilin 2 | -0.00695802 |
| IRS1 | insulin receptor substrate 1 | -0.00695372 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.00692764 |
| CHKA | choline kinase alpha | -0.00691814 |
| ZNF331 | zinc finger protein 331 | -0.00685255 |
| NREP | neuronal regeneration related protein | -0.00684186 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | -0.00683646 |
| BEX1 | brain expressed, X-linked 1 | -0.00680745 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00676751 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | -0.00676034 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00674919 |
| RAPSN | receptor-associated protein of the synapse | -0.00674913 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -0.00674527 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00674081 |
| PRDX2 | peroxiredoxin 2 | -0.00672089 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | -0.00669505 |
| FKBP9 | FK506 binding protein 9, 63 kDa | -0.00666319 |
| TRIP13 | thyroid hormone receptor interactor 13 | -0.00663866 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | -0.00662771 |
| TARDBP | TAR DNA binding protein | -0.00662108 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | -0.00662102 |
| FNBP1 | formin binding protein 1 | -0.00660175 |
| L1CAM | L1 cell adhesion molecule | -0.00654902 |
| FADS1 | fatty acid desaturase 1 | -0.00653841 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00653042 |
| TCERG1 | transcription elongation regulator 1 | -0.00650386 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.00649716 |
| FAM168B | family with sequence similarity 168, member B | -0.00644968 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic | -0.00643802 |
| LMNB2 | lamin B2 | -0.00643328 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.00643115 |
| PTBP1 | polypyrimidine tract binding protein 1 | -0.00642067 |
| TGFB3 | transforming growth factor, beta 3 | -0.0064111 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | -0.00640724 |
| RECQL | RecQ helicase-like | -0.00638349 |
| SCRIB | scribbled planar cell polarity protein | -0.00637667 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0063745 |
| NEFH | neurofilament, heavy polypeptide | -0.00636197 |
| MRPL12 | mitochondrial ribosomal protein L12 | -0.00635785 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00635687 |
| NMU | neuromedin U | -0.00634907 |
| MCM7 | minichromosome maintenance complex component 7 | -0.00634642 |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) | -0.00633085 |
| GAS1 | growth arrest-specific 1 | -0.00633032 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00632899 |
| HMGB2 | high mobility group box 2 | -0.00631891 |
| GSE1 | Gse1 coiled-coil protein | -0.0063139 |
| NUP50 | nucleoporin 50kDa | -0.00630034 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.00627289 |
| TOR4A | torsin family 4, member A | -0.00627057 |
| MLPH | melanophilin | -0.00626763 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00626416 |
| PCGF3 | polycomb group ring finger 3 | -0.00625 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00624494 |
| KLF13 | Kruppel-like factor 13 | -0.00623179 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B | -0.00622281 |
| HAS2 | hyaluronan synthase 2 | -0.00621867 |
| NXN | nucleoredoxin | -0.00620964 |
| AURKB | aurora kinase B | -0.00619429 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00619044 |
| CBX6 | chromobox homolog 6 | -0.00618371 |
| COL6A1 | collagen, type VI, alpha 1 | -0.00618169 |
| TRMT5 | tRNA methyltransferase 5 | -0.00615671 |
| LETM1 | leucine zipper-EF-hand containing transmembrane protein 1 | -0.0061276 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | -0.00612647 |
| COMP | cartilage oligomeric matrix protein | -0.00612453 |
| HDAC1 | histone deacetylase 1 | -0.00611374 |
| CBX5 | chromobox homolog 5 | -0.00610856 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00610285 |
| AMOTL2 | angiomotin like 2 | -0.00609993 |
| SQLE | squalene epoxidase | -0.00606825 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.00605841 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00605558 |
| CSK | c-src tyrosine kinase | -0.00605344 |
| TLN1 | talin 1 | -0.00603819 |
| MAP1B | microtubule-associated protein 1B | -0.00603272 |
| OSR2 | odd-skipped related transciption factor 2 | -0.0060283 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.00602145 |
| SEPTIN10 | septin 10 | -0.00601061 |
| HRASLS | HRAS-like suppressor | -0.00600633 |
| DGCR8 | DGCR8 microprocessor complex subunit | -0.00600142 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00599499 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.00599489 |
| MEN1 | multiple endocrine neoplasia I | -0.00598146 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00596699 |
| FZD2 | frizzled class receptor 2 | -0.00595893 |
| NINJ2 | ninjurin 2 | -0.00594152 |
| GTPBP3 | GTP binding protein 3 (mitochondrial) | -0.00589814 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.00589781 |
| DACH1 | dachshund family transcription factor 1 | -0.00587701 |
| CFD | complement factor D (adipsin) | -0.00587527 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00587031 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.00586464 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.0058612 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00584759 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.00584096 |
| ZNF211 | zinc finger protein 211 | -0.00583663 |
| TAGLN | transgelin | -0.00582312 |
| PIMREG | PICALM interacting mitotic regulator | -0.00582101 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0058132 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | -0.00580549 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.00580195 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 | -0.00578283 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -0.00578267 |
| SETBP1 | SET binding protein 1 | -0.00576879 |
| ESR1 | estrogen receptor 1 | -0.00576852 |
| SLC43A3 | solute carrier family 43, member 3 | -0.00572453 |
| NAA40 | N(alpha)-acetyltransferase 40, NatD catalytic subunit | -0.00571885 |
| FZD10 | frizzled class receptor 10 | -0.00571272 |
| TTN | titin | -0.00570783 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A | -0.00570409 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.00570393 |
| SFPQ | splicing factor proline/glutamine-rich | -0.00569159 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.00568148 |
| FAM120A | family with sequence similarity 120A | -0.00567393 |
| MECOM | MDS1 and EVI1 complex locus | -0.00566604 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 | -0.00565928 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00564964 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.0056492 |
| RGS16 | regulator of G-protein signaling 16 | -0.00564339 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00562978 |
| TFRC | transferrin receptor | -0.00562086 |
| NCOA3 | nuclear receptor coactivator 3 | -0.00561835 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00561529 |
| STON1 | stonin 1 | -0.00561141 |
| CTBP1 | C-terminal binding protein 1 | -0.00560887 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00560786 |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) | -0.00559966 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00558528 |
| DLG5 | discs, large homolog 5 (Drosophila) | -0.00558357 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | -0.00558274 |
| HAMP | hepcidin antimicrobial peptide | -0.00557742 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | -0.00557551 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | -0.00556364 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | -0.00556197 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00555663 |
| NCOA6 | nuclear receptor coactivator 6 | -0.00554609 |
| WASHC5 | WASH complex subunit 5 | -0.00553577 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.00553421 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.00552135 |
| H2AFV | H2A histone family, member V | -0.00550388 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00549445 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00548811 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00548206 |
| TYMS | thymidylate synthetase | -0.00547979 |
| NCOR2 | nuclear receptor corepressor 2 | -0.00547519 |
| LAMA5 | laminin, alpha 5 | -0.00544687 |
| PER3 | period circadian clock 3 | -0.00544444 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00543554 |