CYP2C8 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description cytochrome P450, family 2, subfamily C, polypeptide 8|This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] (NCBI Entrez Gene Database, 1558)
External Link https://ncbi.nlm.nih.gov/gene/1558
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Genes

499 genes differentially expressed following the CYP2C8 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
XPO7 exportin 7 0.0114295
IFI16 interferon, gamma-inducible protein 16 0.0106875
DNTT DNA nucleotidylexotransferase 0.00988336
FBXO11 F-box protein 11 0.00981754
XIC X chromosome inactivation center 0.00952162
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00934034
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00932806
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.0090008
RBM34 RNA binding motif protein 34 0.00895359
TLE4 transducin-like enhancer of split 4 0.00894386
CD200 CD200 molecule 0.00883441
ANXA6 annexin A6 0.00869026
GYPC glycophorin C (Gerbich blood group) 0.00836816
HOXC6 homeobox C6 0.00816908
PDIA3 protein disulfide isomerase family A, member 3 0.00792158
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00789328
DPYSL3 dihydropyrimidinase-like 3 0.00778324
MPO myeloperoxidase 0.00757695
PRPF4 pre-mRNA processing factor 4 0.0075353
S100A7 S100 calcium binding protein A7 0.00746137
TMEM255A transmembrane protein 255A 0.0073067
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00718714
DLD dihydrolipoamide dehydrogenase 0.00715557
SHCBP1 SHC SH2-domain binding protein 1 0.00711547
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.00709469
AUTS2 autism susceptibility candidate 2 0.00707798
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00707194
ALAS2 5'-aminolevulinate synthase 2 0.00703848
PXDN peroxidasin 0.00695519
ADA adenosine deaminase 0.00691024
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00689699
MSN moesin 0.00686705
PBX1 pre-B-cell leukemia homeobox 1 0.00680063
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.00674316
EPB42 erythrocyte membrane protein band 4.2 0.00672165
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00672003
TACC1 transforming, acidic coiled-coil containing protein 1 0.00668081
BNC2 basonuclin 2 0.00667728
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.00661939
FLI1 Fli-1 proto-oncogene, ETS transcription factor 0.00659444
SDC1 syndecan 1 0.0065465
SPRR3 small proline-rich protein 3 0.00651849
AHSP alpha hemoglobin stabilizing protein 0.00650327
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.00649356
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.00648988
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.00642778
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00641087
RAD23B RAD23 homolog B (S. cerevisiae) 0.00632061
CXCL12 chemokine (C-X-C motif) ligand 12 0.00632002
PTHLH parathyroid hormone-like hormone 0.00630349
S100A12 S100 calcium binding protein A12 0.00627822
ZFP36L2 ZFP36 ring finger protein-like 2 0.00621094
RBM38 RNA binding motif protein 38 0.00613054
KIF23 kinesin family member 23 0.00607926
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00607208
MYH10 myosin, heavy chain 10, non-muscle 0.00605057
DHFR dihydrofolate reductase 0.00603238
LMNB1 lamin B1 0.00602856
HBD hemoglobin, delta 0.00601154
FHL1 four and a half LIM domains 1 0.00597395
LARS1 leucyl-tRNA synthetase 1 0.00597338
HDAC6 histone deacetylase 6 0.00597255
RRM2 ribonucleotide reductase M2 0.00597231
PI3 peptidase inhibitor 3, skin-derived 0.00592474
TNS1 tensin 1 0.00592153
TKTL1 transketolase-like 1 0.00589819
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00589406
KIF11 kinesin family member 11 0.00586482
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.00585044
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.0058393
RNF11 ring finger protein 11 0.00582122
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.005799
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.00579074
SELL selectin L 0.00577777
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00575567
VNN1 vanin 1 0.00573953
CD44 CD44 molecule (Indian blood group) 0.00572722
TAL1 T-cell acute lymphocytic leukemia 1 0.00572577
PNMA2 paraneoplastic Ma antigen 2 0.00571753
ARG1 arginase 1 0.00570327
CETN2 centrin, EF-hand protein, 2 0.00569928
RGS4 regulator of G-protein signaling 4 0.00569208
WT1 Wilms tumor 1 0.00568523
MN1 meningioma (disrupted in balanced translocation) 1 0.00567812
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00564556
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.00564473
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 0.00564342
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.00564057
ALDOB aldolase B, fructose-bisphosphate 0.00562131
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.0055981
PRKCA protein kinase C, alpha 0.00558977
CEP55 centrosomal protein 55kDa 0.00551717
TMCC2 transmembrane and coiled-coil domain family 2 0.00551389
SMC2 structural maintenance of chromosomes 2 0.00550607
SOX11 SRY (sex determining region Y)-box 11 0.00550382
C7 complement component 7 0.00545849
KRT13 keratin 13, type I 0.00545719
CYTH1 cytohesin 1 0.00544445
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) 0.00543833
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.0054293
CD48 CD48 molecule 0.00531515
MKI67 marker of proliferation Ki-67 0.00531347
FAM46C family with sequence similarity 46, member C 0.00530801
FANCG Fanconi anemia, complementation group G 0.00529488
BPGM 2,3-bisphosphoglycerate mutase 0.00524442
ITGA8 integrin, alpha 8 0.00523246
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.0052218
EML1 echinoderm microtubule associated protein like 1 0.00521585
CSRP2 cysteine and glycine-rich protein 2 0.00521157
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.0052038
SLIT1 slit homolog 1 (Drosophila) 0.00518403
DCHS1 dachsous cadherin-related 1 0.00516055
RPL10 ribosomal protein L10 0.0051523
PDZK1IP1 PDZK1 interacting protein 1 0.00511888
CANX calnexin 0.00511882
NES nestin 0.00510363
XK X-linked Kx blood group 0.00510227
KIF20A kinesin family member 20A 0.00508583
FOXG1 forkhead box G1 0.00505988
SFRP1 secreted frizzled-related protein 1 0.0050541
HMBS hydroxymethylbilane synthase 0.00504401
LIG1 ligase I, DNA, ATP-dependent 0.00501865
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00501748
SOX17 SRY (sex determining region Y)-box 17 0.0050171
ANK2 ankyrin 2, neuronal 0.00500803
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.00500723
GINS3 GINS complex subunit 3 (Psf3 homolog) 0.00498961
MMRN1 multimerin 1 0.00498068
C9ORF91 chromosome 9 open reading frame 91 0.00496933
KIF18A kinesin family member 18A 0.00493655
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.00493084
DEFB1 defensin, beta 1 0.00489697
FBXO5 F-box protein 5 0.00489329
PRUNE2 prune homolog 2 (Drosophila) 0.00488949
ZNF264 zinc finger protein 264 0.00488428
TRIM68 tripartite motif containing 68 0.00487943
MLEC malectin 0.00487647
ELANE elastase, neutrophil expressed 0.00487137
COL1A2 collagen, type I, alpha 2 0.00486507
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.0048371
LTA4H leukotriene A4 hydrolase 0.00482345
LTBP1 latent transforming growth factor beta binding protein 1 0.00482321
HELLS helicase, lymphoid-specific 0.00481821
KIF5C kinesin family member 5C 0.00479354
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00479333
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 0.00479088
MNDA myeloid cell nuclear differentiation antigen 0.00478725
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 0.00478373
VCAN versican 0.00477248
IL13RA2 interleukin 13 receptor, alpha 2 0.00477227
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00475194
MTMR11 myotubularin related protein 11 0.00474228
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.00473972
GLOD4 glyoxalase domain containing 4 0.00473733
RAD51 RAD51 recombinase 0.00473069
WASF1 WAS protein family, member 1 0.00472946
PRKCH protein kinase C, eta 0.00472411
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.00471558
DPYS dihydropyrimidinase 0.00471056
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.00470773
COPA coatomer protein complex, subunit alpha 0.00470704
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.00469713
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00467952
CBR3 carbonyl reductase 3 0.00466899
UBB ubiquitin B 0.0046612
COG7 component of oligomeric golgi complex 7 0.00465918
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00464858
RECK reversion-inducing-cysteine-rich protein with kazal motifs 0.00464813
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 0.00464616
SRSF1 serine/arginine-rich splicing factor 1 0.00463963
SALL1 spalt-like transcription factor 1 0.00463683
CCNG1 cyclin G1 0.00463386
FECH ferrochelatase 0.00463126
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 0.00461901
CENPN centromere protein N 0.00460355
STC2 stanniocalcin 2 0.00459066
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.00458654
ACOT7 acyl-CoA thioesterase 7 0.00458119
VTCN1 V-set domain containing T cell activation inhibitor 1 0.00457521
NFASC neurofascin 0.00457506
ZNF652 zinc finger protein 652 0.00457403
IRF4 interferon regulatory factor 4 0.00456315
KIF15 kinesin family member 15 0.00456095
NELL2 NEL-like 2 (chicken) 0.0045591
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa 0.00455645
SET SET nuclear proto-oncogene 0.00455325
RRM1 ribonucleotide reductase M1 0.00455177
LAPTM5 lysosomal protein transmembrane 5 0.0045459
NCAPD2 non-SMC condensin I complex, subunit D2 0.00454096
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 0.00452241
CHTOP chromatin target of PRMT1 0.00451423
RNF130 ring finger protein 130 0.00450757
METTL9 methyltransferase like 9 0.00450663
FTO fat mass and obesity associated 0.00450501
LY9 lymphocyte antigen 9 0.00447593
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.00447372
TRAPPC3 trafficking protein particle complex 3 0.00446989
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 0.00446968
RSL1D1 ribosomal L1 domain containing 1 0.00446806
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00446182
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.00444753
SLC35E2B solute carrier family 35, member E2B 0.00444055
CFDP1 craniofacial development protein 1 0.00442101
ALCAM activated leukocyte cell adhesion molecule 0.00440815
GET1 guided entry of tail-anchored proteins factor 1 0.00440565
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.00440522
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.00439897
SMC1A structural maintenance of chromosomes 1A 0.00438971
KLK13 kallikrein-related peptidase 13 0.00438946
KIF18B kinesin family member 18B 0.00438807
STIL SCL/TAL1 interrupting locus 0.00438782
DIAPH2 diaphanous-related formin 2 0.00438424
FKBP14 FK506 binding protein 14, 22 kDa 0.00437958
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.00437199
RCAN1 regulator of calcineurin 1 0.00436402
FSTL1 follistatin-like 1 0.0043564
ERP29 endoplasmic reticulum protein 29 0.00434663
SHB Src homology 2 domain containing adaptor protein B 0.00434373
NIBAN1 niban apoptosis regulator 1 0.00433924
RPA2 replication protein A2, 32kDa 0.00433397
ESD esterase D 0.00431961
CHEK1 checkpoint kinase 1 0.00431954
MRPL24 mitochondrial ribosomal protein L24 0.00431819
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.00431719
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 0.00431168
FBXW11 F-box and WD repeat domain containing 11 0.00430959
COL6A1 collagen, type VI, alpha 1 0.00430722
ADD3 adducin 3 (gamma) 0.00430472
FSD1 fibronectin type III and SPRY domain containing 1 0.00429033
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.00429006
TMX4 thioredoxin-related transmembrane protein 4 0.0042897
PDE4B phosphodiesterase 4B, cAMP-specific 0.00428851
TMOD1 tropomodulin 1 0.00428755
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.00428711
PNMA8A PNMA family member 8A 0.00428034
UIMC1 ubiquitin interaction motif containing 1 0.00427514
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.00427248
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 0.00427043
HCRT hypocretin (orexin) neuropeptide precursor 0.00425967
LGALS13 lectin, galactoside-binding, soluble, 13 0.00425824
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 0.00425066
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.00424798
ADAT1 adenosine deaminase, tRNA-specific 1 0.00423841
FANCI Fanconi anemia, complementation group I 0.00423777
CD1D CD1d molecule 0.00423541
CDC45 cell division cycle 45 0.00423392
DSG3 desmoglein 3 0.00423338
TADA2A transcriptional adaptor 2A 0.00422784
NUSAP1 nucleolar and spindle associated protein 1 0.00422255
ITM2C integral membrane protein 2C 0.00422077

decreased expression

Symbol Name Standardized Value
HSPA1A heat shock 70kDa protein 1A -0.0133273
APOD apolipoprotein D -0.0128843
TM4SF1 transmembrane 4 L six family member 1 -0.0123763
MAP7 microtubule-associated protein 7 -0.0122617
TGFBI transforming growth factor, beta-induced, 68kDa -0.0116508
AKR1C2 aldo-keto reductase family 1, member C2 -0.0116407
DSP desmoplakin -0.0104483
SNAP25 synaptosomal-associated protein, 25kDa -0.0103467
HSPB1 heat shock 27kDa protein 1 -0.0102598
TENT5A terminal nucleotidyltransferase 5A -0.0102241
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.0101066
KRT18 keratin 18, type I -0.00985559
PLIN2 perilipin 2 -0.00979575
KRT7 keratin 7, type II -0.0097394
MMP1 matrix metallopeptidase 1 -0.00967869
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00958399
DYNLL1 dynein, light chain, LC8-type 1 -0.0095178
AKR1C1 aldo-keto reductase family 1, member C1 -0.00944755
F3 coagulation factor III (thromboplastin, tissue factor) -0.00944726
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00940725
CFB complement factor B -0.00939614
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.0093723
TPSAB1 tryptase alpha/beta 1 -0.00936273
WDR7 WD repeat domain 7 -0.00926529
AHR aryl hydrocarbon receptor -0.00905659
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00902002
KRT19 keratin 19, type I -0.00864928
SIK1 salt-inducible kinase 1 -0.00861486
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00847263
PIEZO2 piezo-type mechanosensitive ion channel component 2 -0.00834529
GPNMB glycoprotein (transmembrane) nmb -0.00832685
CHKA choline kinase alpha -0.00832584
H1-2 H1.2 linker histone, cluster member -0.00819234
CXCL2 chemokine (C-X-C motif) ligand 2 -0.0081295
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00810594
SOX9 SRY (sex determining region Y)-box 9 -0.00809904
PERP PERP, TP53 apoptosis effector -0.008025
AGR2 anterior gradient 2 -0.00801121
KRT17 keratin 17, type I -0.00793688
AKR1C3 aldo-keto reductase family 1, member C3 -0.00782925
MT1M metallothionein 1M -0.0078279
STXBP2 syntaxin binding protein 2 -0.00781214
KLF9 Kruppel-like factor 9 -0.00778567
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00759349
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -0.00759227
MT1E metallothionein 1E -0.00757096
FN1 fibronectin 1 -0.00755724
CHN2 chimerin 2 -0.00754034
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00753588
COL15A1 collagen, type XV, alpha 1 -0.00743773
TOX3 TOX high mobility group box family member 3 -0.00737819
EPCAM epithelial cell adhesion molecule -0.00735708
TUBA4A tubulin, alpha 4a -0.00731384
SPP1 secreted phosphoprotein 1 -0.00729213
PXDC1 PX domain containing 1 -0.00728434
GLRX2 glutaredoxin 2 -0.00725829
S100A2 S100 calcium binding protein A2 -0.00724701
BIK BCL2-interacting killer (apoptosis-inducing) -0.00723167
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00722693
PDHX pyruvate dehydrogenase complex, component X -0.0072186
CD36 CD36 molecule (thrombospondin receptor) -0.00717112
AQP3 aquaporin 3 (Gill blood group) -0.00708325
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.00701656
BASP1 brain abundant, membrane attached signal protein 1 -0.00701143
MT1G metallothionein 1G -0.00700136
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00694036
KRT8 keratin 8, type II -0.00693307
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00691714
PEG10 paternally expressed 10 -0.00689678
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.0068575
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00677035
TNNT1 troponin T type 1 (skeletal, slow) -0.00676523
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00671381
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.00671274
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00671108
SCGN secretagogin, EF-hand calcium binding protein -0.00670763
S100A4 S100 calcium binding protein A4 -0.00669559
FTH1 ferritin, heavy polypeptide 1 -0.0066829
CLDN4 claudin 4 -0.00662477
KYNU kynureninase -0.006614
TSPAN13 tetraspanin 13 -0.0065781
RNF43 ring finger protein 43 -0.0065682
MXRA5 matrix-remodelling associated 5 -0.00656181
C8ORF4 chromosome 8 open reading frame 4 -0.00656171
MMP12 matrix metallopeptidase 12 -0.00655832
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00654111
CPB1 carboxypeptidase B1 (tissue) -0.00653908
KRAS Kirsten rat sarcoma viral oncogene homolog -0.00652199
CTSH cathepsin H -0.00650377
MBD2 methyl-CpG binding domain protein 2 -0.00649972
HIST1H2BK histone cluster 1, H2bk -0.00647159
CXADR coxsackie virus and adenovirus receptor -0.00646924
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00644702
JUNB jun B proto-oncogene -0.00642753
PON3 paraoxonase 3 -0.0064004
NEU1 sialidase 1 (lysosomal sialidase) -0.00637004
SCGB1D2 secretoglobin, family 1D, member 2 -0.00636179
PMP22 peripheral myelin protein 22 -0.00634328
MMP9 matrix metallopeptidase 9 -0.00632607
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00632462
MT1X metallothionein 1X -0.00629431
PEG3 paternally expressed 3 -0.00628448
CYB5A cytochrome b5 type A (microsomal) -0.00625847
CPE carboxypeptidase E -0.0062376
MYO6 myosin VI -0.00623612
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00621553
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00621004
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00620089
NUAK1 NUAK family, SNF1-like kinase, 1 -0.00611896
IRS1 insulin receptor substrate 1 -0.00608918
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 -0.00607606
SNX10 sorting nexin 10 -0.00606575
ETNK1 ethanolamine kinase 1 -0.0060629
KCTD14 potassium channel tetramerization domain containing 14 -0.0060619
FNDC3B fibronectin type III domain containing 3B -0.00605323
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00604099
MGST2 microsomal glutathione S-transferase 2 -0.00603965
RTN2 reticulon 2 -0.00603883
S100P S100 calcium binding protein P -0.00596481
TYMP thymidine phosphorylase -0.00594643
CLEC3B C-type lectin domain family 3, member B -0.00591648
TCTA T-cell leukemia translocation altered -0.00590403
WASL Wiskott-Aldrich syndrome-like -0.00589832
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.00587772
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00586184
PLXND1 plexin D1 -0.00584611
IPCEF1 interaction protein for cytohesin exchange factors 1 -0.00584092
PPARG peroxisome proliferator-activated receptor gamma -0.00583979
GMDS GDP-mannose 4,6-dehydratase -0.00581317
IL1RN interleukin 1 receptor antagonist -0.00580048
CCNG2 cyclin G2 -0.00579123
SFN stratifin -0.00577233
CYTL1 cytokine-like 1 -0.0057655
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00574957
HK1 hexokinase 1 -0.00574687
TPD52L1 tumor protein D52-like 1 -0.00573156
MRPS30 mitochondrial ribosomal protein S30 -0.00569253
LSR lipolysis stimulated lipoprotein receptor -0.00568616
SDC4 syndecan 4 -0.00568214
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00567322
PHLDA2 pleckstrin homology-like domain, family A, member 2 -0.00565022
STK26 serine/threonine protein kinase 26 -0.00561153
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00560649
SDC2 syndecan 2 -0.00560613
SMAD7 SMAD family member 7 -0.00560154
IRS2 insulin receptor substrate 2 -0.00558461
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.00557119
CORO1B coronin, actin binding protein, 1B -0.00557061
MMP13 matrix metallopeptidase 13 -0.00556473
CCNA2 cyclin A2 -0.00555659
SOCS2 suppressor of cytokine signaling 2 -0.00551966
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00551012
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -0.00550621
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00548928
RELN reelin -0.00547644
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00544849
CYBA cytochrome b-245, alpha polypeptide -0.00542057
MT1H metallothionein 1H -0.00539021
OSBPL10 oxysterol binding protein-like 10 -0.00538829
GSN gelsolin -0.00537632
KLHL24 kelch-like family member 24 -0.00537312
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00537008
RRAS related RAS viral (r-ras) oncogene homolog -0.00536915
SPHK1 sphingosine kinase 1 -0.00536508
CD163 CD163 molecule -0.0053518
CLU clusterin -0.00534362
DUSP10 dual specificity phosphatase 10 -0.00533961
EXPH5 exophilin 5 -0.00533663
C3 complement component 3 -0.00531899
PRSS8 protease, serine, 8 -0.00531776
DCLK1 doublecortin-like kinase 1 -0.00531368
HMGA1 high mobility group AT-hook 1 -0.00529576
CRYAB crystallin, alpha B -0.0052837
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00527418
HK2 hexokinase 2 -0.00526189
TXNL1 thioredoxin-like 1 -0.00525013
NEBL nebulette -0.00522983
RND3 Rho family GTPase 3 -0.00521845
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00521803
TGFA transforming growth factor, alpha -0.00521675
CCDC86 coiled-coil domain containing 86 -0.00520545
C1S complement component 1, s subcomponent -0.00519417
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00519176
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.00518845
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00518118
PDK3 pyruvate dehydrogenase kinase, isozyme 3 -0.00517425
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00517231
MECOM MDS1 and EVI1 complex locus -0.00513423
AACS acetoacetyl-CoA synthetase -0.00512951
CHKB choline kinase beta -0.00512647
CHMP4A charged multivesicular body protein 4A -0.00511048
PRSS23 protease, serine, 23 -0.00510948
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.00510178
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -0.00509228
EHF ets homologous factor -0.00508316
GOLT1B golgi transport 1B -0.00508182
ANGPT1 angiopoietin 1 -0.005077
SOWAHC sosondowah ankyrin repeat domain family member C -0.00506757
NPEPL1 aminopeptidase-like 1 -0.00505633
RBM47 RNA binding motif protein 47 -0.00503782
COMP cartilage oligomeric matrix protein -0.00503322
IL6 interleukin 6 -0.0050228
TGFB1 transforming growth factor, beta 1 -0.00502082
VAMP8 vesicle-associated membrane protein 8 -0.00501401
CCL19 chemokine (C-C motif) ligand 19 -0.00500875
SNAI2 snail family zinc finger 2 -0.00500212
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa -0.00500166
PDLIM4 PDZ and LIM domain 4 -0.00500163
ZCCHC2 zinc finger, CCHC domain containing 2 -0.00499981
RHOBTB3 Rho-related BTB domain containing 3 -0.0049973
PKM pyruvate kinase, muscle -0.00498739
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00498736
SPATS2L spermatogenesis associated, serine-rich 2-like -0.00498115
GPC3 glypican 3 -0.00495315
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -0.00495308
TES testin LIM domain protein -0.00493631
KIF5B kinesin family member 5B -0.00493581
NEFH neurofilament, heavy polypeptide -0.00491668
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B -0.00491445
CCL8 chemokine (C-C motif) ligand 8 -0.00491025
ADIRF adipogenesis regulatory factor -0.00490641
GOLIM4 golgi integral membrane protein 4 -0.00489829
COL9A3 collagen, type IX, alpha 3 -0.00488905
RCAN2 regulator of calcineurin 2 -0.004887
MARCKSL1 MARCKS-like 1 -0.00488229
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -0.00487505
ELN elastin -0.0048723
IL1R1 interleukin 1 receptor, type I -0.00486946
LDHA lactate dehydrogenase A -0.00486601
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00485635
TBX3 T-box 3 -0.00484896
AMBP alpha-1-microglobulin/bikunin precursor -0.00484771
SCRG1 stimulator of chondrogenesis 1 -0.00484386
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00483397
LIMS1 LIM and senescent cell antigen-like domains 1 -0.00483228
PTGDS prostaglandin D2 synthase 21kDa (brain) -0.00482858
CTSD cathepsin D -0.00480228
PRSS21 protease, serine, 21 (testisin) -0.00480024
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -0.00479846
COMT catechol-O-methyltransferase -0.00479685
ACSL3 acyl-CoA synthetase long-chain family member 3 -0.00478132
YAP1 Yes-associated protein 1 -0.00477899
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) -0.0047772
FSCN1 fascin actin-bundling protein 1 -0.00475774
APOLD1 apolipoprotein L domain containing 1 -0.00475253
MEST mesoderm specific transcript -0.00475008
MAPK6 mitogen-activated protein kinase 6 -0.0047416
NECTIN2 nectin cell adhesion molecule 2 -0.00473516
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00472168