| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cytochrome P450, family 2, subfamily C, polypeptide 9|This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1559) |
| External Link | https://ncbi.nlm.nih.gov/gene/1559 |
| Similar Terms | |
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499 genes differentially expressed following the CYP2C9 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0204255 |
| MGP | matrix Gla protein | 0.0196462 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.016704 |
| A2M | alpha-2-macroglobulin | 0.0164139 |
| EMP1 | epithelial membrane protein 1 | 0.0159443 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.015748 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.015278 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.0151483 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0151128 |
| ANXA1 | annexin A1 | 0.0148336 |
| KRT5 | keratin 5, type II | 0.0144662 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.0144122 |
| SPRR1B | small proline-rich protein 1B | 0.0143293 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.0139012 |
| C3 | complement component 3 | 0.0138668 |
| TRIM22 | tripartite motif containing 22 | 0.0132832 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.013283 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0132742 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.013127 |
| ABLIM1 | actin binding LIM protein 1 | 0.0127526 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.0126454 |
| CSTA | cystatin A (stefin A) | 0.0122983 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0120921 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0120661 |
| NRN1 | neuritin 1 | 0.0120151 |
| KRT6A | keratin 6A, type II | 0.0119957 |
| FN1 | fibronectin 1 | 0.011947 |
| KRT6B | keratin 6B, type II | 0.0119321 |
| KRT17 | keratin 17, type I | 0.0118812 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0118385 |
| CFI | complement factor I | 0.0118125 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.0117921 |
| KRT15 | keratin 15, type I | 0.0117559 |
| SPRR3 | small proline-rich protein 3 | 0.0116911 |
| HSPB1 | heat shock 27kDa protein 1 | 0.011544 |
| RGCC | regulator of cell cycle | 0.0114666 |
| XIC | X chromosome inactivation center | 0.0114289 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0113246 |
| HIST1H2AC | histone cluster 1, H2ac | 0.0111859 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.0111689 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.011142 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.0111135 |
| S100A7 | S100 calcium binding protein A7 | 0.0110897 |
| TUBB2A | tubulin, beta 2A class IIa | 0.0109524 |
| IFI44L | interferon-induced protein 44-like | 0.0108763 |
| ITGA6 | integrin, alpha 6 | 0.0107518 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.0107156 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0106619 |
| GNAS | GNAS complex locus | 0.01057 |
| CCN2 | cellular communication network factor 2 | 0.0104943 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.0104577 |
| MMP7 | matrix metallopeptidase 7 | 0.0103659 |
| SPRR2B | small proline-rich protein 2B | 0.010299 |
| IL1RN | interleukin 1 receptor antagonist | 0.0102641 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0102107 |
| S100A2 | S100 calcium binding protein A2 | 0.0101744 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0101513 |
| KRT14 | keratin 14, type I | 0.0100728 |
| TRIM29 | tripartite motif containing 29 | 0.0100482 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0100174 |
| CNN3 | calponin 3, acidic | 0.00997304 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00996548 |
| CHI3L2 | chitinase 3-like 2 | 0.00995051 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00994176 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 | 0.0099306 |
| PALLD | palladin, cytoskeletal associated protein | 0.00988802 |
| CTSB | cathepsin B | 0.0098757 |
| ADM | adrenomedullin | 0.00983997 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00977122 |
| MAOA | monoamine oxidase A | 0.00975589 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00973923 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00972764 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00970083 |
| FZD6 | frizzled class receptor 6 | 0.00968172 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0096252 |
| SPRR1A | small proline-rich protein 1A | 0.00961346 |
| MYO1C | myosin IC | 0.00958689 |
| COG5 | component of oligomeric golgi complex 5 | 0.00958308 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00958224 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00954221 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00949599 |
| NFIB | nuclear factor I/B | 0.00949461 |
| MT1X | metallothionein 1X | 0.00947574 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00942349 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00940222 |
| KRT13 | keratin 13, type I | 0.00936353 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00931089 |
| GIMAP5 | GTPase, IMAP family member 5 | 0.00930957 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00929393 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00928303 |
| MX1 | MX dynamin-like GTPase 1 | 0.00923342 |
| PERP | PERP, TP53 apoptosis effector | 0.00922512 |
| PALMD | palmdelphin | 0.00921736 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00921271 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.00917739 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00917564 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00916309 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00914526 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00914483 |
| RRAGA | Ras-related GTP binding A | 0.00912 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.00911177 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00910927 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00910715 |
| METTL7A | methyltransferase like 7A | 0.00909162 |
| JAG1 | jagged 1 | 0.00909007 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.00905599 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.00900347 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00899798 |
| CHPT1 | choline phosphotransferase 1 | 0.00896858 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00885411 |
| LAMB3 | laminin, beta 3 | 0.00882094 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00875076 |
| HLA-B | major histocompatibility complex, class I, B | 0.00874432 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00872819 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.00870624 |
| PHF11 | PHD finger protein 11 | 0.00870253 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.00870213 |
| C1S | complement component 1, s subcomponent | 0.00864208 |
| CD163 | CD163 molecule | 0.00863683 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.00863473 |
| KLHL24 | kelch-like family member 24 | 0.00859429 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.00854066 |
| TGM2 | transglutaminase 2 | 0.0085286 |
| IFNGR1 | interferon gamma receptor 1 | 0.0085264 |
| FCGBP | Fc fragment of IgG binding protein | 0.00851914 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00851042 |
| IFI44 | interferon-induced protein 44 | 0.00850311 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00848974 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00847481 |
| LAMC2 | laminin, gamma 2 | 0.00846013 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00844596 |
| NMB | neuromedin B | 0.00840419 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.00837945 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00837641 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00836009 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00834429 |
| MMP12 | matrix metallopeptidase 12 | 0.00829112 |
| PKP1 | plakophilin 1 | 0.00826022 |
| OPHN1 | oligophrenin 1 | 0.00822063 |
| TMEM100 | transmembrane protein 100 | 0.00821833 |
| MPZL2 | myelin protein zero-like 2 | 0.00821732 |
| MT1G | metallothionein 1G | 0.00820985 |
| CFB | complement factor B | 0.00814718 |
| KLK10 | kallikrein-related peptidase 10 | 0.00814235 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00810417 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00806252 |
| IRF6 | interferon regulatory factor 6 | 0.00805276 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00803483 |
| S100A8 | S100 calcium binding protein A8 | 0.00802888 |
| CD9 | CD9 molecule | 0.00798447 |
| SP110 | SP110 nuclear body protein | 0.00790724 |
| SP100 | SP100 nuclear antigen | 0.00789277 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00788114 |
| GIMAP4 | GTPase, IMAP family member 4 | 0.00787874 |
| DSG3 | desmoglein 3 | 0.0078607 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00783336 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00782165 |
| SERINC5 | serine incorporator 5 | 0.00775054 |
| IL6ST | interleukin 6 signal transducer | 0.00774757 |
| MSMB | microseminoprotein, beta- | 0.00774561 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00773169 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 0.00760841 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00758811 |
| TBX3 | T-box 3 | 0.00758126 |
| SCEL | sciellin | 0.0075268 |
| IQCG | IQ motif containing G | 0.00752646 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | 0.00749871 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00749703 |
| CD38 | CD38 molecule | 0.00748245 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00746921 |
| FHL1 | four and a half LIM domains 1 | 0.00745606 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00744278 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00743504 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00743251 |
| MREG | melanoregulin | 0.00743242 |
| HLA-DOB | major histocompatibility complex, class II, DO beta | 0.00739846 |
| GLUL | glutamate-ammonia ligase | 0.0073955 |
| THBD | thrombomodulin | 0.0073831 |
| SERINC1 | serine incorporator 1 | 0.00736842 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00736442 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00733451 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00733167 |
| IGSF1 | immunoglobulin superfamily, member 1 | 0.00730917 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00730452 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00730093 |
| SSX1 | synovial sarcoma, X breakpoint 1 | 0.00729276 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.00728733 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00727759 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.00724844 |
| ZNF277 | zinc finger protein 277 | 0.0072416 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.00723489 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00721393 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.00720103 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.00719229 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00716431 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00715294 |
| RTCA | RNA 3'-terminal phosphate cyclase | 0.007152 |
| FAM189A2 | family with sequence similarity 189, member A2 | 0.0071426 |
| RIN2 | Ras and Rab interactor 2 | 0.0071413 |
| ATP9A | ATPase, class II, type 9A | 0.00712153 |
| HBP1 | HMG-box transcription factor 1 | 0.00707885 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 0.00706856 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00706777 |
| AREG | amphiregulin | 0.00706131 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.00705706 |
| TP63 | tumor protein p63 | 0.00704049 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.0070283 |
| CANX | calnexin | 0.00702132 |
| PRAME | preferentially expressed antigen in melanoma | 0.00700204 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.00698116 |
| LAMA3 | laminin, alpha 3 | 0.00697958 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00697062 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0069582 |
| GLRX | glutaredoxin (thioltransferase) | 0.00694987 |
| TGFA | transforming growth factor, alpha | 0.00694696 |
| TPD52L1 | tumor protein D52-like 1 | 0.00693038 |
| CAV2 | caveolin 2 | 0.00691749 |
| VAMP5 | vesicle-associated membrane protein 5 | 0.00691294 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00691139 |
| RNASET2 | ribonuclease T2 | 0.00690987 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00686889 |
| MT1H | metallothionein 1H | 0.00686824 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | 0.00686572 |
| LY96 | lymphocyte antigen 96 | 0.00685214 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 0.0068409 |
| APOL1 | apolipoprotein L, 1 | 0.00683286 |
| B2M | beta-2-microglobulin | 0.006825 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00680526 |
| STX12 | syntaxin 12 | 0.00679469 |
| GRAMD2B | GRAM domain containing 2B | 0.00678753 |
| MBD2 | methyl-CpG binding domain protein 2 | 0.00678382 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00677573 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00677167 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00673912 |
| VWF | von Willebrand factor | 0.00673699 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00673229 |
| MAL | mal, T-cell differentiation protein | 0.00669318 |
| STOM | stomatin | 0.00669128 |
| RGS10 | regulator of G-protein signaling 10 | 0.0066735 |
| TSPAN7 | tetraspanin 7 | 0.00665771 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00662615 |
| PDCD10 | programmed cell death 10 | 0.0066219 |
| GPC3 | glypican 3 | 0.0066186 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00661026 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.006605 |
| AHNAK | AHNAK nucleoprotein | 0.00658345 |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.0065741 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 | 0.00656931 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.00656077 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | 0.00655006 |
| Symbol | Name | Standardized Value |
|---|---|---|
| METRN | meteorin, glial cell differentiation regulator | -0.0140048 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.0139936 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.0135744 |
| CA2 | carbonic anhydrase II | -0.0121057 |
| MLPH | melanophilin | -0.0114705 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0112551 |
| MAP7 | microtubule-associated protein 7 | -0.0110654 |
| RTN2 | reticulon 2 | -0.010449 |
| STK10 | serine/threonine kinase 10 | -0.0104215 |
| CDC20 | cell division cycle 20 | -0.0100717 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00992606 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0097079 |
| THY1 | Thy-1 cell surface antigen | -0.0095535 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00934531 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00908323 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00906108 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00904985 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00900133 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00899976 |
| ESR1 | estrogen receptor 1 | -0.00893777 |
| HMGN5 | high mobility group nucleosome binding domain 5 | -0.00885558 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00884735 |
| AURKB | aurora kinase B | -0.00876677 |
| EREG | epiregulin | -0.00868454 |
| HBD | hemoglobin, delta | -0.00867877 |
| ELANE | elastase, neutrophil expressed | -0.00867792 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00867684 |
| PRDX2 | peroxiredoxin 2 | -0.00861419 |
| CTH | cystathionine gamma-lyase | -0.00855711 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0085423 |
| FZD2 | frizzled class receptor 2 | -0.00853375 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00852081 |
| RUNX3 | runt-related transcription factor 3 | -0.00851514 |
| COMP | cartilage oligomeric matrix protein | -0.00838958 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00835178 |
| PROM1 | prominin 1 | -0.00834733 |
| ANXA6 | annexin A6 | -0.00816425 |
| DUSP2 | dual specificity phosphatase 2 | -0.00812571 |
| TMSB15A | thymosin beta 15a | -0.00809755 |
| LRRC15 | leucine rich repeat containing 15 | -0.00809476 |
| LIN28A | lin-28 homolog A (C. elegans) | -0.00804688 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | -0.00804639 |
| NKG7 | natural killer cell granule protein 7 | -0.00803771 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00799929 |
| NVL | nuclear VCP-like | -0.00793759 |
| IRX5 | iroquois homeobox 5 | -0.0078721 |
| SCG5 | secretogranin V | -0.00784901 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.0078039 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00773234 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.00768627 |
| NPTX2 | neuronal pentraxin II | -0.00765277 |
| NEFH | neurofilament, heavy polypeptide | -0.00759248 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00758426 |
| PDZK1 | PDZ domain containing 1 | -0.00750042 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00749215 |
| GAS1 | growth arrest-specific 1 | -0.00748468 |
| HOMER3 | homer scaffolding protein 3 | -0.00747726 |
| MRPL12 | mitochondrial ribosomal protein L12 | -0.00746787 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00746538 |
| PLK1 | polo-like kinase 1 | -0.00745711 |
| ASRGL1 | asparaginase like 1 | -0.00744992 |
| FBXO11 | F-box protein 11 | -0.00743688 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | -0.0074065 |
| WT1 | Wilms tumor 1 | -0.00737337 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00729668 |
| CLC | Charcot-Leyden crystal galectin | -0.00729295 |
| CTSG | cathepsin G | -0.00725921 |
| TGFB1 | transforming growth factor, beta 1 | -0.00724963 |
| CDA | cytidine deaminase | -0.00723737 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.0072319 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00722896 |
| H2AX | H2A.X variant histone | -0.00722233 |
| LMNB2 | lamin B2 | -0.00721211 |
| KAZN | kazrin, periplakin interacting protein | -0.00717776 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | -0.00713726 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00713564 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00712623 |
| APMAP | adipocyte plasma membrane associated protein | -0.00708473 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00706673 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | -0.00705701 |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | -0.00702946 |
| CCND1 | cyclin D1 | -0.00698105 |
| TSPAN12 | tetraspanin 12 | -0.00696442 |
| ZNF329 | zinc finger protein 329 | -0.00694492 |
| RXRA | retinoid X receptor, alpha | -0.00693177 |
| PRTN3 | proteinase 3 | -0.00692589 |
| PFAS | phosphoribosylformylglycinamidine synthase | -0.00691175 |
| DACH1 | dachshund family transcription factor 1 | -0.00688215 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | -0.00687961 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | -0.00687284 |
| INSM1 | insulinoma-associated 1 | -0.0068582 |
| PKM | pyruvate kinase, muscle | -0.00682765 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00682607 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.0067728 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -0.00674575 |
| MGLL | monoglyceride lipase | -0.00674025 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00673589 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00672961 |
| AMH | anti-Mullerian hormone | -0.00670429 |
| PLK2 | polo-like kinase 2 | -0.00667812 |
| PDE4A | phosphodiesterase 4A, cAMP-specific | -0.00666472 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | -0.0066528 |
| TK1 | thymidine kinase 1, soluble | -0.00661922 |
| MB | myoglobin | -0.006617 |
| TRAPPC4 | trafficking protein particle complex 4 | -0.00661047 |
| TARP | TCR gamma alternate reading frame protein | -0.00660966 |
| HAL | histidine ammonia-lyase | -0.00659502 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -0.00658873 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00655833 |
| PFKM | phosphofructokinase, muscle | -0.00653022 |
| C9 | complement component 9 | -0.00650236 |
| STXBP2 | syntaxin binding protein 2 | -0.00647877 |
| DTYMK | deoxythymidylate kinase (thymidylate kinase) | -0.0064734 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | -0.00647138 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -0.00646432 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.00645367 |
| ALDOA | aldolase A, fructose-bisphosphate | -0.00644574 |
| HAS2 | hyaluronan synthase 2 | -0.00644382 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00643323 |
| PODXL | podocalyxin-like | -0.0064043 |
| CFP | complement factor properdin | -0.00640204 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00639503 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) | -0.00639097 |
| TPI1 | triosephosphate isomerase 1 | -0.00638886 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00636651 |
| CRTAM | cytotoxic and regulatory T cell molecule | -0.00635085 |
| NANOG | Nanog homeobox | -0.0063468 |
| KRT8 | keratin 8, type II | -0.00634571 |
| NXN | nucleoredoxin | -0.00631226 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | -0.00631105 |
| EGR2 | early growth response 2 | -0.00630314 |
| TECR | trans-2,3-enoyl-CoA reductase | -0.00629248 |
| ZNF45 | zinc finger protein 45 | -0.00626683 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00626593 |
| CBS | cystathionine-beta-synthase | -0.00625559 |
| TUBA4A | tubulin, alpha 4a | -0.00624036 |
| PXDN | peroxidasin | -0.00623299 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00621993 |
| GLB1L2 | galactosidase, beta 1-like 2 | -0.00621894 |
| ABHD17A | abhydrolase domain containing 17A | -0.0062114 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00615908 |
| GAMT | guanidinoacetate N-methyltransferase | -0.00613216 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0060903 |
| TUFT1 | tuftelin 1 | -0.0060817 |
| KLRC3 | killer cell lectin-like receptor subfamily C, member 3 | -0.00608027 |
| QDPR | quinoid dihydropteridine reductase | -0.00608001 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00607243 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00607001 |
| TRHDE | thyrotropin-releasing hormone degrading enzyme | -0.00605987 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00604429 |
| CHKB | choline kinase beta | -0.00604113 |
| VCPKMT | valosin containing protein lysine (K) methyltransferase | -0.00603503 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | -0.00601251 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00596302 |
| EIF4E | eukaryotic translation initiation factor 4E | -0.00596026 |
| HAUS3 | HAUS augmin-like complex, subunit 3 | -0.00593356 |
| SPATA20 | spermatogenesis associated 20 | -0.00593185 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 | -0.00593147 |
| NNMT | nicotinamide N-methyltransferase | -0.00592946 |
| HAUS7 | HAUS augmin-like complex, subunit 7 | -0.00589099 |
| TST | thiosulfate sulfurtransferase (rhodanese) | -0.00589005 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00588954 |
| COL10A1 | collagen, type X, alpha 1 | -0.00588823 |
| AP1M2 | adaptor-related protein complex 1, mu 2 subunit | -0.00588808 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00588597 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0058829 |
| KLRF1 | killer cell lectin-like receptor subfamily F, member 1 | -0.00585128 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00585044 |
| GEMIN4 | gem (nuclear organelle) associated protein 4 | -0.00582923 |
| FST | follistatin | -0.00581573 |
| TFF1 | trefoil factor 1 | -0.00580776 |
| TBL1X | transducin (beta)-like 1X-linked | -0.00579643 |
| PRPF3 | pre-mRNA processing factor 3 | -0.00578622 |
| BLVRB | biliverdin reductase B | -0.00578406 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | -0.00576153 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.00575677 |
| CLGN | calmegin | -0.00575189 |
| PDZD8 | PDZ domain containing 8 | -0.00574729 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.0057331 |
| SMAD7 | SMAD family member 7 | -0.00573291 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | -0.00571942 |
| L1TD1 | LINE-1 type transposase domain containing 1 | -0.00571855 |
| SCAF4 | SR-related CTD-associated factor 4 | -0.00571712 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.00571044 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) | -0.00570238 |
| CRP | C-reactive protein, pentraxin-related | -0.00570068 |
| CRYM | crystallin, mu | -0.00568058 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00567389 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00566754 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00565438 |
| SRRT | serrate, RNA effector molecule | -0.00565097 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00563939 |
| HMBS | hydroxymethylbilane synthase | -0.00563741 |
| CTPS1 | CTP synthase 1 | -0.00563073 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00562679 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | -0.0055938 |
| FEN1 | flap structure-specific endonuclease 1 | -0.00558884 |
| UBE2M | ubiquitin-conjugating enzyme E2M | -0.00558683 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.00557262 |
| FAM149A | family with sequence similarity 149, member A | -0.00556885 |
| PTPRC | protein tyrosine phosphatase, receptor type, C | -0.00555916 |
| INAVA | innate immunity activator | -0.00555836 |
| PKN1 | protein kinase N1 | -0.00555719 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | -0.00555718 |
| FASN | fatty acid synthase | -0.00555593 |
| SELENBP1 | selenium binding protein 1 | -0.00555165 |
| RCAN2 | regulator of calcineurin 2 | -0.00554744 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.00554392 |
| POU5F1P3 | POU class 5 homeobox 1 pseudogene 3 | -0.00553787 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.00552856 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00551037 |
| LETM1 | leucine zipper-EF-hand containing transmembrane protein 1 | -0.00550966 |
| FTO | fat mass and obesity associated | -0.00549934 |
| NAPA | N-ethylmaleimide-sensitive factor attachment protein, alpha | -0.00547439 |
| MRPS2 | mitochondrial ribosomal protein S2 | -0.00546086 |
| GNMT | glycine N-methyltransferase | -0.00545503 |
| PDE10A | phosphodiesterase 10A | -0.0054494 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 | -0.00544352 |
| KIF18B | kinesin family member 18B | -0.00543737 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | -0.00543443 |
| SLC16A6 | solute carrier family 16, member 6 | -0.00541832 |
| XYLT1 | xylosyltransferase I | -0.00540905 |
| PCGF3 | polycomb group ring finger 3 | -0.0054087 |
| NKX2-2 | NK2 homeobox 2 | -0.00540474 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | -0.00539839 |
| RAB17 | RAB17, member RAS oncogene family | -0.00538665 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -0.00538306 |
| CENPB | centromere protein B, 80kDa | -0.00537474 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00537226 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.00537123 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00536905 |
| RHOF | ras homolog family member F (in filopodia) | -0.00536456 |
| TTC38 | tetratricopeptide repeat domain 38 | -0.00536314 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 | -0.00535969 |
| MOK | MOK protein kinase | -0.00535795 |
| CD8A | CD8a molecule | -0.00535711 |
| RECQL4 | RecQ protein-like 4 | -0.00535652 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00533907 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | -0.00533407 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.0053261 |
| ROR2 | receptor tyrosine kinase-like orphan receptor 2 | -0.00532395 |
| HTRA1 | HtrA serine peptidase 1 | -0.00532232 |
| NELFB | negative elongation factor complex member B | -0.00531722 |
| TRIM37 | tripartite motif containing 37 | -0.00529933 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.00528314 |
| DCTD | dCMP deaminase | -0.00528085 |
| LAT2 | linker for activation of T cells family, member 2 | -0.00528084 |
| RNF4 | ring finger protein 4 | -0.00527841 |
| GSE1 | Gse1 coiled-coil protein | -0.005275 |
