| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cytochrome P450, family 2, subfamily E, polypeptide 1|This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1571) |
| External Link | https://ncbi.nlm.nih.gov/gene/1571 |
| Similar Terms | |
| Downloads & Tools |
497 genes differentially expressed following the CYP2E1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SFRP4 | secreted frizzled-related protein 4 | 0.0173119 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.0151766 |
| RGS4 | regulator of G-protein signaling 4 | 0.0141376 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.014136 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0138315 |
| HTRA1 | HtrA serine peptidase 1 | 0.0137575 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0127866 |
| LCN2 | lipocalin 2 | 0.0126523 |
| CTSD | cathepsin D | 0.0124734 |
| PROM1 | prominin 1 | 0.0123647 |
| HIST1H2BD | histone cluster 1, H2bd | 0.0123142 |
| MT1X | metallothionein 1X | 0.0120253 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.0116818 |
| PTK2B | protein tyrosine kinase 2 beta | 0.0116695 |
| CALB1 | calbindin 1, 28kDa | 0.0114799 |
| H1-2 | H1.2 linker histone, cluster member | 0.0112533 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.0111599 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.0109888 |
| WDR7 | WD repeat domain 7 | 0.0109679 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0109194 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0108561 |
| S100A8 | S100 calcium binding protein A8 | 0.0105625 |
| IER5 | immediate early response 5 | 0.0105495 |
| HIST1H2AC | histone cluster 1, H2ac | 0.0102882 |
| THBS1 | thrombospondin 1 | 0.010279 |
| DIPK1A | divergent protein kinase domain 1A | 0.0101816 |
| GAS1 | growth arrest-specific 1 | 0.00991249 |
| PITX3 | paired-like homeodomain 3 | 0.00985108 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00984789 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00980626 |
| NOTCH1 | notch 1 | 0.00977995 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | 0.0096965 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00965229 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00959638 |
| METRN | meteorin, glial cell differentiation regulator | 0.00957972 |
| INHBA | inhibin, beta A | 0.0095522 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.00954573 |
| MT1H | metallothionein 1H | 0.00952497 |
| APOD | apolipoprotein D | 0.00950301 |
| MT1E | metallothionein 1E | 0.00945843 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00942689 |
| MBD2 | methyl-CpG binding domain protein 2 | 0.00940844 |
| RRAGD | Ras-related GTP binding D | 0.00937169 |
| SNAI2 | snail family zinc finger 2 | 0.00936716 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00935966 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00929819 |
| MT1F | metallothionein 1F | 0.00924968 |
| EFHD1 | EF-hand domain family, member D1 | 0.00918653 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00912103 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00911619 |
| FST | follistatin | 0.0091016 |
| BGN | biglycan | 0.00909461 |
| IPO13 | importin 13 | 0.00905659 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.00896255 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00895584 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00894785 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00892891 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.00886001 |
| CRYAB | crystallin, alpha B | 0.00884978 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 0.00880475 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00877799 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.0087421 |
| KRT23 | keratin 23, type I | 0.00869476 |
| DPEP1 | dipeptidase 1 (renal) | 0.00868585 |
| MT1G | metallothionein 1G | 0.00866318 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.0086439 |
| ADD3 | adducin 3 (gamma) | 0.00864239 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.00864193 |
| STK38 | serine/threonine kinase 38 | 0.00861076 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00860663 |
| AREG | amphiregulin | 0.00856809 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0085498 |
| DCN | decorin | 0.00850321 |
| SCPEP1 | serine carboxypeptidase 1 | 0.00847775 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00842608 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00837455 |
| GATA6 | GATA binding protein 6 | 0.00835169 |
| EHD1 | EH-domain containing 1 | 0.00832297 |
| BLNK | B-cell linker | 0.00823432 |
| KLF2 | Kruppel-like factor 2 | 0.00820133 |
| RTN3 | reticulon 3 | 0.00816309 |
| TSLIG3A | tRNA splicing ligase complex subunit 3A | 0.00812788 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.0080839 |
| OAT | ornithine aminotransferase | 0.00802272 |
| GAS6 | growth arrest-specific 6 | 0.00801104 |
| NID2 | nidogen 2 (osteonidogen) | 0.00801076 |
| ECM1 | extracellular matrix protein 1 | 0.00799354 |
| AOC1 | amine oxidase, copper containing 1 | 0.0079552 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00791061 |
| RPS27L | ribosomal protein S27-like | 0.00789238 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00783332 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.00779532 |
| CAST | calpastatin | 0.00777313 |
| QPRT | quinolinate phosphoribosyltransferase | 0.00772242 |
| FSCN1 | fascin actin-bundling protein 1 | 0.00771719 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00765907 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00765133 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00764526 |
| ANXA1 | annexin A1 | 0.00763745 |
| CLIC3 | chloride intracellular channel 3 | 0.00759979 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00759481 |
| EPCAM | epithelial cell adhesion molecule | 0.00754789 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.00750698 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00746185 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.00745668 |
| ZNF91 | zinc finger protein 91 | 0.00744933 |
| AZU1 | azurocidin 1 | 0.00742883 |
| SCG5 | secretogranin V | 0.00738259 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00731982 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.00731635 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00730525 |
| METTL7A | methyltransferase like 7A | 0.00728699 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.0072865 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00727473 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 | 0.00721905 |
| S100P | S100 calcium binding protein P | 0.00721881 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00720019 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00719804 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00719024 |
| SGCE | sarcoglycan, epsilon | 0.00718681 |
| MFAP5 | microfibrillar associated protein 5 | 0.00718557 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0071825 |
| CLDN3 | claudin 3 | 0.007142 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.00713174 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.00712801 |
| OSBPL1A | oxysterol binding protein-like 1A | 0.00709733 |
| FOXD1 | forkhead box D1 | 0.00708946 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.00705012 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00700167 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00699997 |
| ZIC1 | Zic family member 1 | 0.00695844 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00695454 |
| GOLGA8A | golgin A8 family, member A | 0.00694204 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00693296 |
| ZNF423 | zinc finger protein 423 | 0.00684373 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.0068288 |
| COL10A1 | collagen, type X, alpha 1 | 0.00682345 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00680865 |
| CCN2 | cellular communication network factor 2 | 0.00677146 |
| TSPO | translocator protein (18kDa) | 0.00673785 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.00673594 |
| PRSS3 | protease, serine, 3 | 0.00672053 |
| RCAN1 | regulator of calcineurin 1 | 0.00671326 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.00671009 |
| KLK10 | kallikrein-related peptidase 10 | 0.00667446 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00667319 |
| VNN1 | vanin 1 | 0.00666468 |
| ADIRF | adipogenesis regulatory factor | 0.0066587 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00663882 |
| PBLD | phenazine biosynthesis-like protein domain containing | 0.00657387 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 0.00656194 |
| S100A9 | S100 calcium binding protein A9 | 0.00655823 |
| ZNF652 | zinc finger protein 652 | 0.00655468 |
| PEG3 | paternally expressed 3 | 0.00655461 |
| RTN2 | reticulon 2 | 0.00654378 |
| TAGLN | transgelin | 0.00653956 |
| EDN1 | endothelin 1 | 0.0065207 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.00651885 |
| DIO1 | deiodinase, iodothyronine, type I | 0.00650813 |
| TRAPPC6A | trafficking protein particle complex 6A | 0.00648547 |
| VPREB1 | pre-B lymphocyte 1 | 0.00646724 |
| KRT19 | keratin 19, type I | 0.00645331 |
| AMOTL2 | angiomotin like 2 | 0.00644127 |
| MICB | MHC class I polypeptide-related sequence B | 0.00644038 |
| ICAM2 | intercellular adhesion molecule 2 | 0.00642852 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | 0.00642218 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00641824 |
| PPIF | peptidylprolyl isomerase F | 0.00641267 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.00640524 |
| UMOD | uromodulin | 0.00640408 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.00639784 |
| BBX | bobby sox homolog (Drosophila) | 0.00637717 |
| MAL | mal, T-cell differentiation protein | 0.0063661 |
| GOLGA8H | golgin A8 family, member H | 0.00634214 |
| CLTB | clathrin, light chain B | 0.00632553 |
| RRAGC | Ras-related GTP binding C | 0.00632226 |
| BAX | BCL2-associated X protein | 0.00630933 |
| G0S2 | G0/G1 switch 2 | 0.00629816 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.00628405 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | 0.00627518 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.0062679 |
| VEGFC | vascular endothelial growth factor C | 0.00626146 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0062575 |
| ZNF329 | zinc finger protein 329 | 0.00619318 |
| HOMER3 | homer scaffolding protein 3 | 0.00618789 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.0061854 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00618484 |
| NUTF2 | nuclear transport factor 2 | 0.00617703 |
| C7 | complement component 7 | 0.00617461 |
| STC2 | stanniocalcin 2 | 0.0061618 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.00613958 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00613891 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.00613562 |
| E2F2 | E2F transcription factor 2 | 0.00611754 |
| WASL | Wiskott-Aldrich syndrome-like | 0.00610622 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00609328 |
| CUTA | cutA divalent cation tolerance homolog (E. coli) | 0.00605523 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00603014 |
| PLK2 | polo-like kinase 2 | 0.00602845 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.00602335 |
| SP100 | SP100 nuclear antigen | 0.00600648 |
| GUCY2C | guanylate cyclase 2C | 0.00600457 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00600185 |
| ZNF264 | zinc finger protein 264 | 0.00597089 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00596483 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00594954 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00594927 |
| RHOBTB1 | Rho-related BTB domain containing 1 | 0.00593489 |
| ZNF706 | zinc finger protein 706 | 0.00592477 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 | 0.0059176 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.00591191 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0059105 |
| SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporter), member 1 | 0.00590447 |
| HIST1H2BH | histone cluster 1, H2bh | 0.00589469 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00588477 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) | 0.00587039 |
| CAPN1 | calpain 1, (mu/I) large subunit | 0.0058505 |
| CYTH1 | cytohesin 1 | 0.00583521 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00582979 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00582342 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | 0.00581328 |
| EBNA1BP2 | EBNA1 binding protein 2 | 0.00580511 |
| USP25 | ubiquitin specific peptidase 25 | 0.0057981 |
| MRC2 | mannose receptor, C type 2 | 0.00578402 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.00574691 |
| NCF1C | neutrophil cytosolic factor 1C pseudogene | 0.00574286 |
| LAMB1 | laminin, beta 1 | 0.0057339 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.00572831 |
| ZNF271P | zinc finger protein 271, pseudogene | 0.00571255 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.00570022 |
| NRCAM | neuronal cell adhesion molecule | 0.0057002 |
| TWIST1 | twist family bHLH transcription factor 1 | 0.00568623 |
| PHF1 | PHD finger protein 1 | 0.00568577 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00567746 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.00565809 |
| IRS1 | insulin receptor substrate 1 | 0.00565296 |
| SCAND1 | SCAN domain containing 1 | 0.00564791 |
| TXNL1 | thioredoxin-like 1 | 0.00564527 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00563584 |
| XYLT1 | xylosyltransferase I | 0.0055975 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.0055858 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.00555641 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0055447 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F | 0.00552262 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 | 0.00552137 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.00551459 |
| TOB1 | transducer of ERBB2, 1 | 0.00550729 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00549604 |
| RAP2A | RAP2A, member of RAS oncogene family | 0.00549315 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.0143752 |
| A2M | alpha-2-macroglobulin | -0.0138054 |
| TNC | tenascin C | -0.0133339 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.0118869 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0115552 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -0.0114329 |
| COPS7A | COP9 signalosome subunit 7A | -0.0113042 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0110484 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.010828 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0106688 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.0106585 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.0105637 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.0105591 |
| TGM2 | transglutaminase 2 | -0.0105239 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.0104647 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0104007 |
| COL15A1 | collagen, type XV, alpha 1 | -0.0102885 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | -0.0102264 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.0101364 |
| CD2 | CD2 molecule | -0.0100438 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00963209 |
| SNX10 | sorting nexin 10 | -0.00962992 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00946289 |
| PDHX | pyruvate dehydrogenase complex, component X | -0.00927691 |
| C1S | complement component 1, s subcomponent | -0.0091844 |
| PRDX2 | peroxiredoxin 2 | -0.0091447 |
| CD99 | CD99 molecule | -0.00913167 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00911758 |
| RAB38 | RAB38, member RAS oncogene family | -0.00882155 |
| RHOA | ras homolog family member A | -0.00875875 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00871788 |
| GPC3 | glypican 3 | -0.0084963 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00849435 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00846696 |
| PHB2 | prohibitin 2 | -0.00846654 |
| RETREG1 | reticulophagy regulator 1 | -0.00840447 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00839677 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00839264 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00836082 |
| YBX3 | Y box binding protein 3 | -0.00834153 |
| IL2RB | interleukin 2 receptor, beta | -0.00831728 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00823775 |
| PRAME | preferentially expressed antigen in melanoma | -0.00821916 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.00818676 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.00812152 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00809606 |
| CHN1 | chimerin 1 | -0.008068 |
| SHTN1 | shootin 1 | -0.00800464 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00794753 |
| FOXF1 | forkhead box F1 | -0.00787273 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00787201 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.00772945 |
| PRF1 | perforin 1 (pore forming protein) | -0.00764409 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00763069 |
| CST3 | cystatin C | -0.00758758 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.00752662 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0075096 |
| MOCOS | molybdenum cofactor sulfurase | -0.00749848 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00749297 |
| FABP6 | fatty acid binding protein 6, ileal | -0.00749214 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00748297 |
| MLF2 | myeloid leukemia factor 2 | -0.0074811 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00747825 |
| APOC2 | apolipoprotein C-II | -0.00745911 |
| YME1L1 | YME1-like 1 ATPase | -0.00745032 |
| CCND1 | cyclin D1 | -0.00738113 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.00735829 |
| SPRR1B | small proline-rich protein 1B | -0.0073491 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.00734737 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00732726 |
| KRT1 | keratin 1, type II | -0.0072529 |
| BCHE | butyrylcholinesterase | -0.00721942 |
| OLFM1 | olfactomedin 1 | -0.0071978 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | -0.00715083 |
| ACTB | actin, beta | -0.00713745 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.00712062 |
| GANAB | glucosidase, alpha; neutral AB | -0.00708449 |
| TXNL4B | thioredoxin-like 4B | -0.00708088 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -0.00707041 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.00704944 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00703072 |
| PMF1 | polyamine-modulated factor 1 | -0.0070179 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | -0.00701517 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0069912 |
| GIMAP5 | GTPase, IMAP family member 5 | -0.00696236 |
| CADM1 | cell adhesion molecule 1 | -0.00695643 |
| HBB | hemoglobin, beta | -0.00695296 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00695287 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00694765 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | -0.00693452 |
| AIM2 | absent in melanoma 2 | -0.00693258 |
| LAMA4 | laminin, alpha 4 | -0.00690914 |
| NRN1 | neuritin 1 | -0.00687909 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.0068684 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.00686212 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.00685841 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00685538 |
| GIMAP4 | GTPase, IMAP family member 4 | -0.00680641 |
| NIBAN1 | niban apoptosis regulator 1 | -0.006801 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00679066 |
| CCR7 | chemokine (C-C motif) receptor 7 | -0.00676298 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | -0.00674279 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00673743 |
| ACP3 | acid phosphatase 3 | -0.00671336 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.00669229 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.00668183 |
| NPTX2 | neuronal pentraxin II | -0.00666227 |
| IRF8 | interferon regulatory factor 8 | -0.00661561 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00659876 |
| CD8A | CD8a molecule | -0.00659788 |
| GPX3 | glutathione peroxidase 3 | -0.00658828 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.00658024 |
| C3 | complement component 3 | -0.00657657 |
| SEPTIN10 | septin 10 | -0.00657617 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | -0.0065532 |
| MREG | melanoregulin | -0.00647422 |
| HSPB8 | heat shock 22kDa protein 8 | -0.0064665 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein | -0.00645631 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.00642367 |
| TAGLN2 | transgelin 2 | -0.00641525 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.00641471 |
| CD163 | CD163 molecule | -0.00641468 |
| TP63 | tumor protein p63 | -0.00635997 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | -0.0063528 |
| COL4A2 | collagen, type IV, alpha 2 | -0.00631433 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00630991 |
| EPAS1 | endothelial PAS domain protein 1 | -0.00630412 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00628939 |
| C1R | complement component 1, r subcomponent | -0.00627523 |
| KIF20A | kinesin family member 20A | -0.00626316 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00624906 |
| NTS | neurotensin | -0.00624352 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.00620208 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00618761 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00617868 |
| SELL | selectin L | -0.00616682 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | -0.00616269 |
| TPI1 | triosephosphate isomerase 1 | -0.00614438 |
| SRP9 | signal recognition particle 9kDa | -0.00614224 |
| PRMT1 | protein arginine methyltransferase 1 | -0.00612585 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00609786 |
| COPA | coatomer protein complex, subunit alpha | -0.00607408 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.0060551 |
| AXL | AXL receptor tyrosine kinase | -0.00604945 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | -0.00604804 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.00604486 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | -0.00603707 |
| PRKCB | protein kinase C, beta | -0.00603418 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00601722 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.00601591 |
| APOC1 | apolipoprotein C-I | -0.0060141 |
| PGD | phosphogluconate dehydrogenase | -0.00600884 |
| RNF130 | ring finger protein 130 | -0.00599602 |
| TIMELESS | timeless circadian clock | -0.00596672 |
| KRT13 | keratin 13, type I | -0.00593379 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00593297 |
| MAP3K7CL | MAP3K7 C-terminal like | -0.00592505 |
| RBPMS | RNA binding protein with multiple splicing | -0.00591567 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | -0.00591362 |
| TMX1 | thioredoxin-related transmembrane protein 1 | -0.00590746 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00590409 |
| CSF1R | colony stimulating factor 1 receptor | -0.00588703 |
| PRL | prolactin | -0.00588348 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00586872 |
| TYRP1 | tyrosinase-related protein 1 | -0.00582983 |
| MAGEA4 | melanoma antigen family A4 | -0.0058283 |
| COL1A2 | collagen, type I, alpha 2 | -0.00582808 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00582668 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.00581577 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00580592 |
| CLDND1 | claudin domain containing 1 | -0.00577422 |
| SORD | sorbitol dehydrogenase | -0.00576731 |
| IL32 | interleukin 32 | -0.00575775 |
| NELL2 | NEL-like 2 (chicken) | -0.00573388 |
| ACACA | acetyl-CoA carboxylase alpha | -0.00572833 |
| RHOB | ras homolog family member B | -0.00572767 |
| PMP22 | peripheral myelin protein 22 | -0.00572056 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00571053 |
| NNT | nicotinamide nucleotide transhydrogenase | -0.00570501 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.00570215 |
| SPON2 | spondin 2, extracellular matrix protein | -0.0057014 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.00569113 |
| FASN | fatty acid synthase | -0.00566044 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00565806 |
| PRC1 | protein regulator of cytokinesis 1 | -0.00565592 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.00565137 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00563561 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.0056342 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | -0.00561712 |
| TMEM176B | transmembrane protein 176B | -0.00560979 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.00560498 |
| CTSH | cathepsin H | -0.00559373 |
| LIG1 | ligase I, DNA, ATP-dependent | -0.00558914 |
| RHOH | ras homolog family member H | -0.00558091 |
| PMM2 | phosphomannomutase 2 | -0.00557325 |
| CH25H | cholesterol 25-hydroxylase | -0.00556158 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00555657 |
| TLR2 | toll-like receptor 2 | -0.00555461 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | -0.00555071 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.00551889 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -0.00551482 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) | -0.00551447 |
| CD34 | CD34 molecule | -0.00551413 |
| GYG2 | glycogenin 2 | -0.00550158 |
| TNS1 | tensin 1 | -0.00549538 |
| VWF | von Willebrand factor | -0.00549536 |
| SRSF7 | serine/arginine-rich splicing factor 7 | -0.0054928 |
| FABP7 | fatty acid binding protein 7, brain | -0.00548541 |
| COL4A6 | collagen, type IV, alpha 6 | -0.00548449 |
| PLTP | phospholipid transfer protein | -0.00546728 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | -0.00546244 |
| TMEM45A | transmembrane protein 45A | -0.00544964 |
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 | -0.00541381 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.00541329 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00540346 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00540306 |
| TRAF1 | TNF receptor-associated factor 1 | -0.00539881 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00539863 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.00539223 |
| NMT2 | N-myristoyltransferase 2 | -0.00539168 |
| CA9 | carbonic anhydrase IX | -0.00538906 |
| CAPNS1 | calpain, small subunit 1 | -0.00538104 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 | -0.00537836 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00536623 |
| HOMER2 | homer scaffolding protein 2 | -0.00536613 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -0.0053568 |
| TSPAN6 | tetraspanin 6 | -0.00535535 |
| NEK7 | NIMA-related kinase 7 | -0.00535446 |
| SCARB1 | scavenger receptor class B, member 1 | -0.00534048 |
| SRP72 | signal recognition particle 72kDa | -0.00533545 |
| CD164 | CD164 molecule, sialomucin | -0.0053259 |
| RLN1 | relaxin 1 | -0.00532413 |
| PEX19 | peroxisomal biogenesis factor 19 | -0.0053139 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.00531178 |
| ZNF266 | zinc finger protein 266 | -0.00530737 |
| CCR2 | chemokine (C-C motif) receptor 2 | -0.00530383 |
| LAG3 | lymphocyte-activation gene 3 | -0.00530248 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00530207 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | -0.0052923 |
| CALML5 | calmodulin-like 5 | -0.00529148 |
| PGC | progastricsin (pepsinogen C) | -0.00528929 |
| RAPSN | receptor-associated protein of the synapse | -0.00528137 |
| UTRN | utrophin | -0.0052784 |
| MAPK1 | mitogen-activated protein kinase 1 | -0.00526809 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | -0.00526196 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.00525852 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.00525097 |
| CTSC | cathepsin C | -0.00524463 |
