| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cytochrome P450, family 3, subfamily A, polypeptide 5|This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] (NCBI Entrez Gene Database, 1577) |
| External Link | https://ncbi.nlm.nih.gov/gene/1577 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the CYP3A5 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERINC5 | serine incorporator 5 | 0.0136467 |
| XIC | X chromosome inactivation center | 0.0130874 |
| KRT13 | keratin 13, type I | 0.0129037 |
| SYT1 | synaptotagmin I | 0.0124996 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0118425 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.0107183 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.010697 |
| KYNU | kynureninase | 0.0102218 |
| S100P | S100 calcium binding protein P | 0.0100647 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0100357 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00998559 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00990179 |
| PHIP | pleckstrin homology domain interacting protein | 0.00981782 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0096979 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00965652 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00965181 |
| CSTA | cystatin A (stefin A) | 0.00956023 |
| NELL2 | NEL-like 2 (chicken) | 0.00945967 |
| FGG | fibrinogen gamma chain | 0.00942216 |
| MX1 | MX dynamin-like GTPase 1 | 0.00935757 |
| C7 | complement component 7 | 0.00932812 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00924853 |
| SPRR3 | small proline-rich protein 3 | 0.00920288 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00914383 |
| MATN2 | matrilin 2 | 0.00914306 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00909706 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.00906111 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00880936 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00873962 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.00831518 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00812756 |
| MGP | matrix Gla protein | 0.00808523 |
| FGF13 | fibroblast growth factor 13 | 0.00798783 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00792244 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00791754 |
| RTCA | RNA 3'-terminal phosphate cyclase | 0.00785648 |
| L1CAM | L1 cell adhesion molecule | 0.00784081 |
| GPX2 | glutathione peroxidase 2 | 0.00782305 |
| DCLK1 | doublecortin-like kinase 1 | 0.00773765 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00770934 |
| RAB25 | RAB25, member RAS oncogene family | 0.00764364 |
| NEFH | neurofilament, heavy polypeptide | 0.00758466 |
| TYRP1 | tyrosinase-related protein 1 | 0.00747671 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00737681 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00734857 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 0.00734345 |
| RPS26 | ribosomal protein S26 | 0.00729649 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00727556 |
| RET | ret proto-oncogene | 0.00724173 |
| SCEL | sciellin | 0.00719427 |
| SPRR1B | small proline-rich protein 1B | 0.00716883 |
| RGS5 | regulator of G-protein signaling 5 | 0.00716079 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00715109 |
| AREG | amphiregulin | 0.00714875 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.0071173 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00710433 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00710081 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00704722 |
| CHGB | chromogranin B | 0.00699535 |
| NEBL | nebulette | 0.00695768 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0069556 |
| PON3 | paraoxonase 3 | 0.00694389 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.00694068 |
| EHD3 | EH-domain containing 3 | 0.00691065 |
| S100A8 | S100 calcium binding protein A8 | 0.0068927 |
| NDNF | neuron-derived neurotrophic factor | 0.00685253 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.00684937 |
| TCTA | T-cell leukemia translocation altered | 0.00682823 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.00681269 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00680637 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00678648 |
| AUTS2 | autism susceptibility candidate 2 | 0.00676213 |
| KRT15 | keratin 15, type I | 0.0067077 |
| ZNF638 | zinc finger protein 638 | 0.00668923 |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | 0.00668046 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | 0.00667827 |
| FN1 | fibronectin 1 | 0.00665627 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00663808 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.00662896 |
| DES | desmin | 0.00659765 |
| ZNF430 | zinc finger protein 430 | 0.0065795 |
| BEX1 | brain expressed, X-linked 1 | 0.00656263 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00655198 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.00655133 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00654175 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.00648569 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00645602 |
| CD93 | CD93 molecule | 0.00642998 |
| NVL | nuclear VCP-like | 0.00640256 |
| GNAS | GNAS complex locus | 0.00637774 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.00637606 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00634073 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00631276 |
| INA | internexin neuronal intermediate filament protein, alpha | 0.00630701 |
| MTF2 | metal response element binding transcription factor 2 | 0.00627315 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00624419 |
| SERINC1 | serine incorporator 1 | 0.0062386 |
| EPCAM | epithelial cell adhesion molecule | 0.0062354 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00622262 |
| HEATR1 | HEAT repeat containing 1 | 0.00621418 |
| SVIL | supervillin | 0.00620722 |
| EGFL6 | EGF-like-domain, multiple 6 | 0.00619304 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.00618268 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00617652 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.00613982 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00613567 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00612901 |
| TMEM255A | transmembrane protein 255A | 0.00609166 |
| TGFA | transforming growth factor, alpha | 0.00609059 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.00606462 |
| RHCG | Rh family, C glycoprotein | 0.00604756 |
| ZNF721 | zinc finger protein 721 | 0.0060412 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.00602746 |
| AFF1 | AF4/FMR2 family, member 1 | 0.00600202 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.00598127 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.0059719 |
| EIF6 | eukaryotic translation initiation factor 6 | 0.00595507 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00595462 |
| POU4F1 | POU class 4 homeobox 1 | 0.00590477 |
| TP63 | tumor protein p63 | 0.00589274 |
| BMP7 | bone morphogenetic protein 7 | 0.00588823 |
| PRPH | peripherin | 0.00588728 |
| EMP2 | epithelial membrane protein 2 | 0.00588186 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 0.00588091 |
| KRT6A | keratin 6A, type II | 0.00588061 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00586124 |
| SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 | 0.00585771 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | 0.00584387 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.00583474 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00583124 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00582533 |
| ATF3 | activating transcription factor 3 | 0.00579058 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.00578787 |
| CTBP2 | C-terminal binding protein 2 | 0.00578717 |
| FCN3 | ficolin (collagen/fibrinogen domain containing) 3 | 0.00578449 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00578238 |
| PDLIM1 | PDZ and LIM domain 1 | 0.00578229 |
| IRS2 | insulin receptor substrate 2 | 0.00576819 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.00576594 |
| MSMB | microseminoprotein, beta- | 0.00575514 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) | 0.00575083 |
| PTK6 | protein tyrosine kinase 6 | 0.00574904 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.00573831 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00573641 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.00572625 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.00572132 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00570929 |
| OGA | O-GlcNAcase | 0.00570023 |
| NCOA3 | nuclear receptor coactivator 3 | 0.00569803 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.00567495 |
| YME1L1 | YME1-like 1 ATPase | 0.00567478 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00567199 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00567066 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.00566893 |
| BAG3 | BCL2-associated athanogene 3 | 0.00564337 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00563306 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.00563204 |
| SDC1 | syndecan 1 | 0.00560485 |
| MYO1D | myosin ID | 0.00560125 |
| SELE | selectin E | 0.00559608 |
| ALOX15B | arachidonate 15-lipoxygenase, type B | 0.00559244 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00557509 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.00557212 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 | 0.00556635 |
| TFF1 | trefoil factor 1 | 0.00555666 |
| LPIN1 | lipin 1 | 0.0055563 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0055524 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00555133 |
| PRKCH | protein kinase C, eta | 0.00555038 |
| COQ8A | coenzyme Q8A | 0.00553311 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.00552917 |
| INSR | insulin receptor | 0.00552509 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 0.00550214 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.00549965 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00549117 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0054888 |
| C1ORF56 | chromosome 1 open reading frame 56 | 0.00548191 |
| CLCA2 | chloride channel accessory 2 | 0.00546176 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0054572 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | 0.0054546 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | 0.00545385 |
| TGM2 | transglutaminase 2 | 0.00544603 |
| TNS1 | tensin 1 | 0.0054451 |
| PLCB4 | phospholipase C, beta 4 | 0.00544455 |
| PERP | PERP, TP53 apoptosis effector | 0.00544387 |
| DUSP4 | dual specificity phosphatase 4 | 0.00544305 |
| HEBP2 | heme binding protein 2 | 0.00543418 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.00542831 |
| SARAF | store-operated calcium entry-associated regulatory factor | 0.00541812 |
| SFTPC | surfactant protein C | 0.00541381 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00540576 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00540512 |
| NAGK | N-acetylglucosamine kinase | 0.00540381 |
| RBM5 | RNA binding motif protein 5 | 0.00539972 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00539156 |
| SPRR1A | small proline-rich protein 1A | 0.00535166 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | 0.00533745 |
| GPR143 | G protein-coupled receptor 143 | 0.00532919 |
| KLK11 | kallikrein-related peptidase 11 | 0.00532251 |
| PCP4 | Purkinje cell protein 4 | 0.00531286 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.00531175 |
| ZNF84 | zinc finger protein 84 | 0.00531076 |
| NPTX2 | neuronal pentraxin II | 0.00530546 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.00529661 |
| F9 | coagulation factor IX | 0.00528417 |
| NAP1L2 | nucleosome assembly protein 1-like 2 | 0.00528357 |
| MAGEA4 | melanoma antigen family A4 | 0.00527563 |
| MPZL2 | myelin protein zero-like 2 | 0.0052734 |
| RREB1 | ras responsive element binding protein 1 | 0.00526442 |
| LOC105375355 | uroplakin-3b | 0.00526122 |
| RASA4 | RAS p21 protein activator 4 | 0.00525782 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00524824 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.00522511 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.00522191 |
| CLDN1 | claudin 1 | 0.00522189 |
| APOD | apolipoprotein D | 0.00521854 |
| CES1 | carboxylesterase 1 | 0.00519754 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00517652 |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) | 0.00516993 |
| HBB | hemoglobin, beta | 0.00516827 |
| PSAP | prosaposin | 0.00516804 |
| IVL | involucrin | 0.00516739 |
| MPDZ | multiple PDZ domain protein | 0.00516501 |
| SLC38A2 | solute carrier family 38, member 2 | 0.00515208 |
| WDR26 | WD repeat domain 26 | 0.00514938 |
| MAGEA12 | melanoma antigen family A12 | 0.00513737 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00512827 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00512745 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.0051213 |
| SERTAD2 | SERTA domain containing 2 | 0.00512125 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00512122 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00511964 |
| ATG3 | autophagy related 3 | 0.00511911 |
| CTTN | cortactin | 0.00511273 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00510857 |
| PRRC2C | proline-rich coiled-coil 2C | 0.00510485 |
| RBM26 | RNA binding motif protein 26 | 0.00509111 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00508394 |
| OFD1 | oral-facial-digital syndrome 1 | 0.00508302 |
| SYNPO | synaptopodin | 0.00508239 |
| TRIM29 | tripartite motif containing 29 | 0.00506954 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | 0.00506826 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00506336 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00505957 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.00505514 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | 0.00502962 |
| ACP3 | acid phosphatase 3 | 0.00501671 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.0050008 |
| CD99 | CD99 molecule | 0.00499098 |
| AZIN1 | antizyme inhibitor 1 | 0.00498339 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.0187117 |
| RNF167 | ring finger protein 167 | -0.0132752 |
| NNMT | nicotinamide N-methyltransferase | -0.0120972 |
| CHP1 | calcineurin-like EF-hand protein 1 | -0.0117668 |
| POSTN | periostin, osteoblast specific factor | -0.0115144 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0108523 |
| LOX | lysyl oxidase | -0.0107323 |
| GPX1 | glutathione peroxidase 1 | -0.0100442 |
| CA12 | carbonic anhydrase XII | -0.0100424 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00974881 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | -0.00952975 |
| CCND1 | cyclin D1 | -0.00925782 |
| METRN | meteorin, glial cell differentiation regulator | -0.00913194 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -0.0091079 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00901096 |
| BSG | basigin (Ok blood group) | -0.00893089 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00885519 |
| GOLM1 | golgi membrane protein 1 | -0.0087356 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00872255 |
| EMP3 | epithelial membrane protein 3 | -0.00863811 |
| MT1E | metallothionein 1E | -0.00854136 |
| TGFB1 | transforming growth factor, beta 1 | -0.00852637 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00850147 |
| GFAP | glial fibrillary acidic protein | -0.00846362 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.0084072 |
| RPA3 | replication protein A3, 14kDa | -0.0083946 |
| CD320 | CD320 molecule | -0.0083774 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00835979 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00835322 |
| EFHD1 | EF-hand domain family, member D1 | -0.00832404 |
| COMP | cartilage oligomeric matrix protein | -0.00830074 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00820263 |
| EVI2A | ecotropic viral integration site 2A | -0.00817924 |
| UBE2S | ubiquitin-conjugating enzyme E2S | -0.0081639 |
| MRPL12 | mitochondrial ribosomal protein L12 | -0.00814695 |
| SIRT3 | sirtuin 3 | -0.00807675 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00806903 |
| TMEM14A | transmembrane protein 14A | -0.00804324 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0080339 |
| CRLF1 | cytokine receptor-like factor 1 | -0.0079718 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00795589 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.00795542 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00794831 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00788439 |
| CALR | calreticulin | -0.00784681 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.00783323 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00783116 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00777684 |
| HNMT | histamine N-methyltransferase | -0.00767757 |
| LTF | lactotransferrin | -0.00767586 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.0076577 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00762643 |
| SRGN | serglycin | -0.00757628 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | -0.00751996 |
| PCLAF | PCNA clamp associated factor | -0.00750303 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00750263 |
| GPR88 | G protein-coupled receptor 88 | -0.00745775 |
| MMP11 | matrix metallopeptidase 11 | -0.00738523 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | -0.00738268 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00736809 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00736597 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00735884 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00734903 |
| PKM | pyruvate kinase, muscle | -0.0072924 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.00725638 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00718736 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00716918 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00716582 |
| HPGDS | hematopoietic prostaglandin D synthase | -0.00710815 |
| IL32 | interleukin 32 | -0.00710215 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00706385 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -0.00704019 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.00702083 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00701593 |
| CNN3 | calponin 3, acidic | -0.00696864 |
| PIH1D1 | PIH1 domain containing 1 | -0.00696051 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00694258 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | -0.00693992 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00693441 |
| MTA1 | metastasis associated 1 | -0.00692838 |
| MMP7 | matrix metallopeptidase 7 | -0.00689332 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00688913 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00686698 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00686332 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00684388 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | -0.00684254 |
| BAD | BCL2-associated agonist of cell death | -0.00682434 |
| RANBP1 | RAN binding protein 1 | -0.00680314 |
| NINJ2 | ninjurin 2 | -0.00678848 |
| MRPS12 | mitochondrial ribosomal protein S12 | -0.00678249 |
| LACTB2 | lactamase, beta 2 | -0.00675829 |
| ZNF580 | zinc finger protein 580 | -0.00674147 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | -0.00673877 |
| UBE2M | ubiquitin-conjugating enzyme E2M | -0.00672924 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I | -0.00670758 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00670082 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | -0.00668431 |
| LRRC17 | leucine rich repeat containing 17 | -0.00665313 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00663809 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | -0.00663503 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00660932 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.0066082 |
| SST | somatostatin | -0.00660544 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.00657538 |
| IL17RB | interleukin 17 receptor B | -0.00655579 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00655318 |
| HMGB3 | high mobility group box 3 | -0.00651775 |
| C1QBP | complement component 1, q subcomponent binding protein | -0.0064798 |
| DAD1 | defender against cell death 1 | -0.00644812 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00644422 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 | -0.00641477 |
| CA2 | carbonic anhydrase II | -0.00639507 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00636031 |
| SLC44A4 | solute carrier family 44, member 4 | -0.00634756 |
| EXOSC4 | exosome component 4 | -0.00634015 |
| PLK1 | polo-like kinase 1 | -0.00633203 |
| HOXB2 | homeobox B2 | -0.0063218 |
| WBP5 | WW domain binding protein 5 | -0.00630079 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | -0.00627539 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 | -0.00625398 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00624236 |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 | -0.0062131 |
| GRAMD2B | GRAM domain containing 2B | -0.00621176 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.00620017 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0061811 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00617383 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | -0.00614889 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | -0.00613899 |
| S100A4 | S100 calcium binding protein A4 | -0.00613623 |
| NME1 | NME/NM23 nucleoside diphosphate kinase 1 | -0.00612412 |
| LSM1 | LSM1, U6 small nuclear RNA associated | -0.00611874 |
| FTL | ferritin, light polypeptide | -0.00611539 |
| THAP12 | THAP domain containing 12 | -0.00609311 |
| MXRA7 | matrix-remodelling associated 7 | -0.00608225 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | -0.00605533 |
| DUSP2 | dual specificity phosphatase 2 | -0.00604652 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | -0.0059974 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.00598906 |
| CDC20 | cell division cycle 20 | -0.00598886 |
| SKP1 | S-phase kinase-associated protein 1 | -0.00598835 |
| LEPROT | leptin receptor overlapping transcript | -0.00598752 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00597046 |
| BANF1 | barrier to autointegration factor 1 | -0.00596155 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | -0.00594117 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | -0.00592045 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00591163 |
| PENK | proenkephalin | -0.0058868 |
| PLAT | plasminogen activator, tissue | -0.00587131 |
| COL3A1 | collagen, type III, alpha 1 | -0.0058698 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00586803 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.0058665 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.0058425 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.00583681 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | -0.00583603 |
| CHKB | choline kinase beta | -0.00580828 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.00579715 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | -0.00579318 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 | -0.00578708 |
| BIN2 | bridging integrator 2 | -0.00577067 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0057618 |
| DCK | deoxycytidine kinase | -0.00573642 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00570963 |
| COPE | coatomer protein complex, subunit epsilon | -0.00569574 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00569132 |
| PTMS | parathymosin | -0.00568865 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00567015 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.00566914 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00566454 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -0.00566445 |
| AK4 | adenylate kinase 4 | -0.00566444 |
| TMEM126B | transmembrane protein 126B | -0.00565972 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | -0.00564927 |
| PHB | prohibitin | -0.00561863 |
| CST3 | cystatin C | -0.00561774 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | -0.00561661 |
| NXT2 | nuclear transport factor 2-like export factor 2 | -0.00558257 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | -0.00556874 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00556202 |
| PITX3 | paired-like homeodomain 3 | -0.0055577 |
| CIDEC | cell death-inducing DFFA-like effector c | -0.00554575 |
| PNPLA2 | patatin-like phospholipase domain containing 2 | -0.00553264 |
| DIO2 | deiodinase, iodothyronine, type II | -0.00552939 |
| ATP13A3 | ATPase type 13A3 | -0.00551422 |
| RRAGA | Ras-related GTP binding A | -0.00551328 |
| TTC38 | tetratricopeptide repeat domain 38 | -0.00550652 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00549744 |
| ARL2 | ADP-ribosylation factor-like 2 | -0.00549144 |
| CD69 | CD69 molecule | -0.00549103 |
| COX11 | COX11 cytochrome c oxidase copper chaperone | -0.00548112 |
| GAMT | guanidinoacetate N-methyltransferase | -0.00547933 |
| KLF13 | Kruppel-like factor 13 | -0.00547261 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 | -0.00545729 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -0.00544352 |
| EMC6 | ER membrane protein complex subunit 6 | -0.00543899 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -0.0054316 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 | -0.00542315 |
| VASP | vasodilator-stimulated phosphoprotein | -0.00540756 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00539727 |
| FASN | fatty acid synthase | -0.00539648 |
| SMYD3 | SET and MYND domain containing 3 | -0.00538674 |
| PFN2 | profilin 2 | -0.0053795 |
| ADORA2B | adenosine A2b receptor | -0.00537251 |
| PRMT1 | protein arginine methyltransferase 1 | -0.00537145 |
| NPR3 | natriuretic peptide receptor 3 | -0.00536943 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.00534522 |
| STXBP2 | syntaxin binding protein 2 | -0.00533305 |
| PFN1 | profilin 1 | -0.005326 |
| COL5A1 | collagen, type V, alpha 1 | -0.00532554 |
| CNTN1 | contactin 1 | -0.00532192 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00529075 |
| TLCD3A | TLC domain containing 3A | -0.00528328 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00527135 |
| CFB | complement factor B | -0.00526983 |
| S100A2 | S100 calcium binding protein A2 | -0.00524301 |
| EVA1B | eva-1 homolog B (C. elegans) | -0.00524153 |
| TMEM106C | transmembrane protein 106C | -0.00523774 |
| MEX3D | mex-3 RNA binding family member D | -0.00522751 |
| RUVBL1 | RuvB-like AAA ATPase 1 | -0.00521356 |
| LYPLA1 | lysophospholipase I | -0.00521168 |
| TOX | thymocyte selection-associated high mobility group box | -0.00520533 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00520286 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00520254 |
| TRIP6 | thyroid hormone receptor interactor 6 | -0.00518509 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -0.00518116 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00515597 |
| RUVBL2 | RuvB-like AAA ATPase 2 | -0.00515066 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00514443 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00513204 |
| TECR | trans-2,3-enoyl-CoA reductase | -0.00512402 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00512176 |
| MRPL17 | mitochondrial ribosomal protein L17 | -0.00511741 |
| LIMA1 | LIM domain and actin binding 1 | -0.00509794 |
| CTSG | cathepsin G | -0.00508848 |
| KLHDC3 | kelch domain containing 3 | -0.00508508 |
| ZWINT | ZW10 interacting kinetochore protein | -0.00507764 |
| RFK | riboflavin kinase | -0.00505108 |
| DENND2B | DENN domain containing 2B | -0.00505072 |
| LOXL2 | lysyl oxidase-like 2 | -0.00502837 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00502676 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | -0.00501396 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.00500701 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.00500347 |
| TSPOAP1 | TSPO associated protein 1 | -0.00499538 |
| NPC2 | Niemann-Pick disease, type C2 | -0.00498037 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 | -0.00497671 |
| NSL1 | NSL1, MIS12 kinetochore complex component | -0.00497396 |
| CLCA1 | chloride channel accessory 1 | -0.00495937 |
| GTPBP8 | GTP-binding protein 8 (putative) | -0.00493595 |
| TMEM165 | transmembrane protein 165 | -0.0049338 |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | -0.00491186 |
