CaR-1 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description Human rectal carcinoma cell line. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003131)
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Genes

357 genes with high or low expression in CaR-1 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
DUSP14 dual specificity phosphatase 14 3.60177
NUP160 nucleoporin 160kDa 3.35708
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 2.64618
CCL2 chemokine (C-C motif) ligand 2 2.59957
CXCL5 chemokine (C-X-C motif) ligand 5 2.55527
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 2.53646
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 2.53646
ANXA2P2 annexin A2 pseudogene 2 2.42484
USP25 ubiquitin specific peptidase 25 2.36613
CNOT6 CCR4-NOT transcription complex, subunit 6 2.20931
ITGB8 integrin, beta 8 2.20631
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 2.17951
PKP4 plakophilin 4 2.15639
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 2.09474
CAST calpastatin 2.07753
BTG3 BTG family, member 3 2.07405
TLR6 toll-like receptor 6 2.04357
TADA2A transcriptional adaptor 2A 2.03154
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 2.01433
KISS1 KiSS-1 metastasis-suppressor 2.01423
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 2.01165
MAPK9 mitogen-activated protein kinase 9 2.01065
TCHH trichohyalin 1.98007
PTTG1IP pituitary tumor-transforming 1 interacting protein 1.95943
OTUD4 OTU deubiquitinase 4 1.94075
CXCL3 chemokine (C-X-C motif) ligand 3 1.93674
BID BH3 interacting domain death agonist 1.93504
CHMP3 charged multivesicular body protein 3 1.92842
MRPL33 mitochondrial ribosomal protein L33 1.91728
CALB1 calbindin 1, 28kDa 1.91666
SNX24 sorting nexin 24 1.90781
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 1.90265
GALR2 galanin receptor 2 1.88335
CFLAR CASP8 and FADD-like apoptosis regulator 1.86762
PANX1 pannexin 1 1.84946
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 1.8392
PDE4B phosphodiesterase 4B, cAMP-specific 1.82695
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 1.81437
TLR1 toll-like receptor 1 1.80068
PDE8A phosphodiesterase 8A 1.77229
VNN1 vanin 1 1.75398
ECHDC1 ethylmalonyl-CoA decarboxylase 1 1.75374
KLK5 kallikrein-related peptidase 5 1.74324
TMED7 transmembrane emp24 protein transport domain containing 7 1.74024
SAA1 serum amyloid A1 1.72999
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.71762
ANXA2P3 annexin A2 pseudogene 3 1.71721
AKTIP AKT interacting protein 1.715
ADAM10 ADAM metallopeptidase domain 10 1.69585
GRAMD3 GRAM domain containing 3 1.69237
H3F3B H3 histone, family 3B (H3.3B) 1.6871
STEAP4 STEAP family member 4 1.68032
PLA2G16 phospholipase A2, group XVI 1.67377
PMEPA1 prostate transmembrane protein, androgen induced 1 1.66533
THBS1 thrombospondin 1 1.65938
HDAC9 histone deacetylase 9 1.65033
LCN2 lipocalin 2 1.64594
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 1.62717
ICMT isoprenylcysteine carboxyl methyltransferase 1.62693
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.62382
PHLDA3 pleckstrin homology-like domain, family A, member 3 1.62266
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.61222
SUMO4 small ubiquitin-like modifier 4 1.60771
MMP7 matrix metallopeptidase 7 1.60719
SAA4 serum amyloid A4, constitutive 1.60578
UGCG UDP-glucose ceramide glucosyltransferase 1.59644
TMOD3 tropomodulin 3 (ubiquitous) 1.5949
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 1.5915
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 1.59057
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 1.58721
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 1.58673
ART3 ADP-ribosyltransferase 3 1.58386
INHBA inhibin, beta A 1.58077
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.57891
EDN1 endothelin 1 1.57767
CTSV cathepsin V 1.57508
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 1.57393
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 1.57145
ITGB6 integrin, beta 6 1.56887
PDGFB platelet-derived growth factor beta polypeptide 1.56663
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 1.56009
SOCS6 suppressor of cytokine signaling 6 1.55832
ADAM9 ADAM metallopeptidase domain 9 1.5566
ICT1 immature colon carcinoma transcript 1 1.55029
ZW10 zw10 kinetochore protein 1.54283
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 1.53412
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 1.53134
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 1.52275
IGBP1 immunoglobulin (CD79A) binding protein 1 1.51614
KRT6B keratin 6B, type II 1.50145
TRIM2 tripartite motif containing 2 1.49662
SLC39A8 solute carrier family 39 (zinc transporter), member 8 1.49072
MYO1E myosin IE 1.49061
MPZL1 myelin protein zero-like 1 1.48278
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.47925
VTCN1 V-set domain containing T cell activation inhibitor 1 1.47566
NT5C2 5'-nucleotidase, cytosolic II 1.4753
MAP3K2 mitogen-activated protein kinase kinase kinase 2 1.47124
TGFA transforming growth factor, alpha 1.46854
TXNDC9 thioredoxin domain containing 9 1.46543
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 1.45777
RGS10 regulator of G-protein signaling 10 1.45741
SRI sorcin 1.45679
GPR87 G protein-coupled receptor 87 1.44914
PPCS phosphopantothenoylcysteine synthetase 1.44606
BIRC2 baculoviral IAP repeat containing 2 1.44413
EXOSC9 exosome component 9 1.44228
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding) 1.44219
NT5C 5', 3'-nucleotidase, cytosolic 1.44002
SSFA2 sperm specific antigen 2 1.43447
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 1.43132
PHKB phosphorylase kinase, beta 1.43084
CST6 cystatin E/M 1.42736
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 1.42541
GPC4 glypican 4 1.41791

low expression

Symbol Name Standardized Value
NT5M 5',3'-nucleotidase, mitochondrial -3.46634
TOB2 transducer of ERBB2, 2 -3.46336
PAN2 PAN2 poly(A) specific ribonuclease subunit -3.42797
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 -3.01564
WNT2B wingless-type MMTV integration site family, member 2B -2.92063
CD4 CD4 molecule -2.91511
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 -2.87183
KDM8 lysine (K)-specific demethylase 8 -2.84263
ACVRL1 activin A receptor type II-like 1 -2.75271
SPPL2B signal peptide peptidase like 2B -2.72247
KLF8 Kruppel-like factor 8 -2.58629
MEPE matrix extracellular phosphoglycoprotein -2.58249
GCM1 glial cells missing homolog 1 (Drosophila) -2.51772
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 -2.47798
DROSHA drosha, ribonuclease type III -2.47213
WDR59 WD repeat domain 59 -2.46909
BAZ2A bromodomain adjacent to zinc finger domain, 2A -2.44823
MAGEB4 melanoma antigen family B4 -2.44312
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma -2.44096
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 -2.41672
BRD8 bromodomain containing 8 -2.41218
PRDM8 PR domain containing 8 -2.4092
NF2 neurofibromin 2 (merlin) -2.4079
SEMG2 semenogelin II -2.39289
NPY neuropeptide Y -2.37643
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) -2.36892
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -2.35774
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 -2.32178
BANP BTG3 associated nuclear protein -2.2923
METTL3 methyltransferase like 3 -2.27892
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 -2.26942
STK11 serine/threonine kinase 11 -2.25123
NTNG1 netrin G1 -2.24814
ZNF135 zinc finger protein 135 -2.24085
WDR60 WD repeat domain 60 -2.21997
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 -2.20611
KIAA0907 KIAA0907 -2.18991
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -2.13911
ZNF682 zinc finger protein 682 -2.137
WDR25 WD repeat domain 25 -2.13187
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 -2.12955
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 -2.12433
NELL2 NEL-like 2 (chicken) -2.11684
ABHD6 abhydrolase domain containing 6 -2.11428
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon -2.10844
LARS2 leucyl-tRNA synthetase 2, mitochondrial -2.10225
IL25 interleukin 25 -2.10149
TXNL4B thioredoxin-like 4B -2.07532
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -2.06901
NIN ninein (GSK3B interacting protein) -2.06366
SCTR secretin receptor -2.04719
NOL12 nucleolar protein 12 -2.04205
EEF1G eukaryotic translation elongation factor 1 gamma -2.04139
OPRD1 opioid receptor, delta 1 -2.03481
HIST1H3B histone cluster 1, H3b -2.02715
ZNF14 zinc finger protein 14 -2.02704
TBCD tubulin folding cofactor D -2.02001
ANKRD7 ankyrin repeat domain 7 -2.01144
KLHL3 kelch-like family member 3 -2.00159
LOC399491 -1.98809
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene -1.97485
ZNF248 zinc finger protein 248 -1.96204
YME1L1 YME1-like 1 ATPase -1.96093
FASLG Fas ligand (TNF superfamily, member 6) -1.95803
MAGEC3 melanoma antigen family C3 -1.95367
CLEC16A C-type lectin domain family 16, member A -1.94882
PITX3 paired-like homeodomain 3 -1.94607
TIGD6 tigger transposable element derived 6 -1.94601
HSPB2 heat shock 27kDa protein 2 -1.91325
RND2 Rho family GTPase 2 -1.9086
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -1.89891
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 -1.89658
HIBADH 3-hydroxyisobutyrate dehydrogenase -1.88693
PDGFRB platelet-derived growth factor receptor, beta polypeptide -1.86946
ESYT1 extended synaptotagmin-like protein 1 -1.86876
NELL1 NEL-like 1 (chicken) -1.86108
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 -1.85726
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 -1.85336
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -1.85194
AOC3 amine oxidase, copper containing 3 -1.84992
GRIK5 glutamate receptor, ionotropic, kainate 5 -1.84842
CASC5 cancer susceptibility candidate 5 -1.8445
TYRP1 tyrosinase-related protein 1 -1.84193
NXF1 nuclear RNA export factor 1 -1.82856
FAM53C family with sequence similarity 53, member C -1.82591
ZNF692 zinc finger protein 692 -1.81347
CEP152 centrosomal protein 152kDa -1.80935
PSRC1 proline/serine-rich coiled-coil 1 -1.80504
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -1.80402
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide -1.80293
DNTT DNA nucleotidylexotransferase -1.80282
MRPL2 mitochondrial ribosomal protein L2 -1.79822
FKBP11 FK506 binding protein 11, 19 kDa -1.79521
LTB4R leukotriene B4 receptor -1.79307
NPFF neuropeptide FF-amide peptide precursor -1.78745
SYP synaptophysin -1.78372
DUS2 dihydrouridine synthase 2 -1.78348
FMNL2 formin-like 2 -1.76984
SPHK2 sphingosine kinase 2 -1.76543
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 -1.7648
PYY2 peptide YY, 2 (pseudogene) -1.7604
LIMD2 LIM domain containing 2 -1.76037
CD163 CD163 molecule -1.75836
CAPRIN2 caprin family member 2 -1.74421
HOXD4 homeobox D4 -1.7384
C1QB complement component 1, q subcomponent, B chain -1.72679
UBP1 upstream binding protein 1 (LBP-1a) -1.71859
PCDHGA9 protocadherin gamma subfamily A, 9 -1.7183
CHIT1 chitinase 1 (chitotriosidase) -1.71792
LTB4R2 leukotriene B4 receptor 2 -1.71635
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) -1.71064
PLA2R1 phospholipase A2 receptor 1, 180kDa -1.71003
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase -1.70979
TAS2R16 taste receptor, type 2, member 16 -1.70745
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) -1.70461
CSNK1D casein kinase 1, delta -1.69835
GLT8D1 glycosyltransferase 8 domain containing 1 -1.69769
EDA ectodysplasin A -1.69731
SPRY4 sprouty homolog 4 (Drosophila) -1.69333
MAST3 microtubule associated serine/threonine kinase 3 -1.68918
GPR17 G protein-coupled receptor 17 -1.68918
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 -1.68764
TRIM58 tripartite motif containing 58 -1.68722
RHOBTB2 Rho-related BTB domain containing 2 -1.68703
FAM110D family with sequence similarity 110, member D -1.68585
NOMO2 NODAL modulator 2 -1.68347
SLC45A2 solute carrier family 45, member 2 -1.68054
TAS2R14 taste receptor, type 2, member 14 -1.68041
TMEM39B transmembrane protein 39B -1.6775
PTGDS prostaglandin D2 synthase 21kDa (brain) -1.67486
UPB1 ureidopropionase, beta -1.67364
TCF3 transcription factor 3 -1.67159
ZFR2 zinc finger RNA binding protein 2 -1.66857
SETD1B SET domain containing 1B -1.66815
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 -1.66707
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -1.66679
ANGPT2 angiopoietin 2 -1.6639
FBXL8 F-box and leucine-rich repeat protein 8 -1.66383
WAC WW domain containing adaptor with coiled-coil -1.6632
LUC7L LUC7-like (S. cerevisiae) -1.66299
ACIN1 apoptotic chromatin condensation inducer 1 -1.65637
CD6 CD6 molecule -1.64926
KANK3 KN motif and ankyrin repeat domains 3 -1.64607
ZFHX2 zinc finger homeobox 2 -1.64567
CNGB1 cyclic nucleotide gated channel beta 1 -1.64515
TBC1D10B TBC1 domain family, member 10B -1.64127
MUM1 melanoma associated antigen (mutated) 1 -1.63486
PRAMEF10 PRAME family member 10 -1.63319
MED23 mediator complex subunit 23 -1.63014
CSAG2 CSAG family, member 2 -1.61836
MUSK muscle, skeletal, receptor tyrosine kinase -1.61173
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) -1.60811
NRXN3 neurexin 3 -1.60621
NECAB2 N-terminal EF-hand calcium binding protein 2 -1.60264
S100PBP S100P binding protein -1.60237
IFNA13 interferon, alpha 13 -1.5999
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1 -1.59843
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -1.59499
KIN Kin17 DNA and RNA binding protein -1.59045
ALOX12B arachidonate 12-lipoxygenase, 12R type -1.58528
MUC13 mucin 13, cell surface associated -1.5824
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) -1.57978
KIAA1467 KIAA1467 -1.57915
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -1.57789
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -1.57657
SIN3B SIN3 transcription regulator family member B -1.5692
ZFP64 ZFP64 zinc finger protein -1.5677
ZBTB24 zinc finger and BTB domain containing 24 -1.56302
SLC30A4 solute carrier family 30 (zinc transporter), member 4 -1.56162
JMJD6 jumonji domain containing 6 -1.56122
POLRMT polymerase (RNA) mitochondrial (DNA directed) -1.56068
NGF nerve growth factor (beta polypeptide) -1.55934
LY86 lymphocyte antigen 86 -1.55751
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A -1.55654
TMEM161A transmembrane protein 161A -1.55652
COL14A1 collagen, type XIV, alpha 1 -1.55399
MXD4 MAX dimerization protein 4 -1.55103
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6 -1.54728
PUS1 pseudouridylate synthase 1 -1.54599
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) -1.53548
LPAL2 lipoprotein, Lp(a)-like 2, pseudogene -1.53262
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) -1.5312
LINC00652 long intergenic non-protein coding RNA 652 -1.5305
RBMXL2 RNA binding motif protein, X-linked-like 2 -1.53044
THAP3 THAP domain containing, apoptosis associated protein 3 -1.52135
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) -1.51904
PGLYRP4 peptidoglycan recognition protein 4 -1.51753
MSH5 mutS homolog 5 -1.51492
POU3F4 POU class 3 homeobox 4 -1.51486
WSB1 WD repeat and SOCS box containing 1 -1.51407
ZNF444 zinc finger protein 444 -1.51097
EBF2 early B-cell factor 2 -1.50623
OXT oxytocin/neurophysin I prepropeptide -1.50532
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 -1.50347
MEP1B meprin A, beta -1.50177
ZMYND8 zinc finger, MYND-type containing 8 -1.49956
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) -1.48852
ABI3BP ABI family, member 3 (NESH) binding protein -1.48824
ACTR6 ARP6 actin-related protein 6 homolog (yeast) -1.48353
TOP2B topoisomerase (DNA) II beta 180kDa -1.48041
PQLC3 PQ loop repeat containing 3 -1.47753
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) -1.4771
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) -1.47373
ARID1A AT rich interactive domain 1A (SWI-like) -1.4719
CRYBA1 crystallin, beta A1 -1.47034
TNPO2 transportin 2 -1.46917
HBZ hemoglobin, zeta -1.46677
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 -1.4662
CLEC10A C-type lectin domain family 10, member A -1.46386
WIZ widely interspaced zinc finger motifs -1.45971
IL17B interleukin 17B -1.45902
PIAS4 protein inhibitor of activated STAT, 4 -1.45656
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme -1.45295
DPF1 D4, zinc and double PHD fingers family 1 -1.45216
PEX5 peroxisomal biogenesis factor 5 -1.45061
SUGP2 SURP and G patch domain containing 2 -1.44778
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 -1.44684
CABIN1 calcineurin binding protein 1 -1.44572
HEYL hes-related family bHLH transcription factor with YRPW motif-like -1.44472
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 -1.44126
MXD1 MAX dimerization protein 1 -1.43954
XPO6 exportin 6 -1.4394
ARSF arylsulfatase F -1.43874
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -1.43625
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) -1.43583
CARD8 caspase recruitment domain family, member 8 -1.43465
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa -1.4335
HAPLN2 hyaluronan and proteoglycan link protein 2 -1.43348
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2 -1.43219
PCDH9 protocadherin 9 -1.43167
PTTG2 pituitary tumor-transforming 2 -1.43157
GYS2 glycogen synthase 2 (liver) -1.43086
NUP43 nucleoporin 43kDa -1.42771
NABP2 nucleic acid binding protein 2 -1.42626
PLEKHO1 pleckstrin homology domain containing, family O member 1 -1.42455
MEN1 multiple endocrine neoplasia I -1.424
VENTXP1 VENT homeobox pseudogene 1 -1.42363
CSNK1G2 casein kinase 1, gamma 2 -1.42352
FLI1 Fli-1 proto-oncogene, ETS transcription factor -1.42329
ANGPT4 angiopoietin 4 -1.42141
TNP1 transition protein 1 (during histone to protamine replacement) -1.41846
PRR14 proline rich 14 -1.41597