| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cabozantinib (S-malate) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cabozantinib (S-malate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 0.160282 |
| NFIB | nuclear factor I/B | 0.134196 |
| PDGFC | platelet derived growth factor C | 0.133772 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.106819 |
| MEOX2 | mesenchyme homeobox 2 | 0.0947624 |
| BOC | BOC cell adhesion associated, oncogene regulated | 0.0856398 |
| COL1A2 | collagen, type I, alpha 2 | 0.0844348 |
| RANBP17 | RAN binding protein 17 | 0.0806753 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.080008 |
| PEG10 | paternally expressed 10 | 0.0761697 |
| OGA | O-GlcNAcase | 0.0761166 |
| PTMA | prothymosin, alpha | 0.0721795 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0709815 |
| MEST | mesoderm specific transcript | 0.0704993 |
| CALR | calreticulin | 0.0702339 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0690249 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0685245 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0682487 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0676127 |
| MGP | matrix Gla protein | 0.0662563 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.065884 |
| RPS6 | ribosomal protein S6 | 0.0625303 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0616469 |
| NFIA | nuclear factor I/A | 0.0610628 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0593794 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0584512 |
| ZNF608 | zinc finger protein 608 | 0.0581233 |
| MATR3 | matrin 3 | 0.0572572 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0556617 |
| UTRN | utrophin | 0.0552332 |
| KAZN | kazrin, periplakin interacting protein | 0.0541053 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0540633 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0540244 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0498432 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0491995 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0488311 |
| HOXA3 | homeobox A3 | 0.0477698 |
| GSE1 | Gse1 coiled-coil protein | 0.0472661 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0470807 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0468932 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0465077 |
| RPL13A | ribosomal protein L13a | 0.0464704 |
| RNF145 | ring finger protein 145 | 0.0444954 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0443018 |
| SHROOM3 | shroom family member 3 | 0.043765 |
| SMYD3 | SET and MYND domain containing 3 | 0.0429188 |
| RAD51B | RAD51 paralog B | 0.0428812 |
| RPS20 | ribosomal protein S20 | 0.0418124 |
| ZNF292 | zinc finger protein 292 | 0.040915 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0409088 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0407853 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0402752 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0401899 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0400014 |
| B2M | beta-2-microglobulin | 0.0396617 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0391766 |
| SET | SET nuclear proto-oncogene | 0.0391124 |
| DIPK2A | divergent protein kinase domain 2A | 0.0389883 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0384542 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0381429 |
| RPS3 | ribosomal protein S3 | 0.0381174 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0377884 |
| NCOR2 | nuclear receptor corepressor 2 | 0.037767 |
| TMSB4X | thymosin beta 4, X-linked | 0.0375869 |
| RPLP0 | ribosomal protein, large, P0 | 0.0372617 |
| ZNF148 | zinc finger protein 148 | 0.0367592 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0366035 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0365747 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0365038 |
| HIP1 | huntingtin interacting protein 1 | 0.0355682 |
| TNS3 | tensin 3 | 0.0355564 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0352313 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0348862 |
| WWOX | WW domain containing oxidoreductase | 0.0345454 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0345112 |
| ATRNL1 | attractin-like 1 | 0.0344209 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0335121 |
| LNX1 | ligand of numb-protein X 1, E3 ubiquitin protein ligase | 0.0333703 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0332206 |
| MLEC | malectin | 0.0331761 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0329571 |
| VEGFA | vascular endothelial growth factor A | 0.0328977 |
| HELLS | helicase, lymphoid-specific | 0.0326381 |
| RPL8 | ribosomal protein L8 | 0.0324057 |
| YBX1 | Y box binding protein 1 | 0.032404 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0323482 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0323113 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0322593 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0322359 |
| RBM33 | RNA binding motif protein 33 | 0.032066 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0320404 |
| HYOU1 | hypoxia up-regulated 1 | 0.0319934 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0319729 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0317379 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0316873 |
| MMS22L | MMS22-like, DNA repair protein | 0.0316636 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0316463 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0315022 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0314831 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0314303 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.133235 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0957379 |
| IER3 | immediate early response 3 | -0.0829323 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0789489 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0689527 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0658698 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0644851 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0622521 |
| FNIP1 | folliculin interacting protein 1 | -0.0585617 |
| MYOF | myoferlin | -0.0532799 |
| SEPTIN11 | septin 11 | -0.0528369 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0452711 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0444989 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0406024 |
| FRMD6 | FERM domain containing 6 | -0.0403435 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.0396539 |
| HMGA1 | high mobility group AT-hook 1 | -0.0390731 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0390475 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0390468 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0380341 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.036731 |
| HMGA2 | high mobility group AT-hook 2 | -0.0366457 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0362931 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0362796 |
| ANO6 | anoctamin 6 | -0.0349134 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0341164 |
| RPS24 | ribosomal protein S24 | -0.0339499 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0324897 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.032251 |
| RAI1 | retinoic acid induced 1 | -0.0315435 |
| DENND5A | DENN/MADD domain containing 5A | -0.0306691 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.03035 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0301639 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0293781 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0291198 |
| CREM | cAMP responsive element modulator | -0.0289965 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0289775 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0282654 |
| TRIM9 | tripartite motif containing 9 | -0.0278969 |
| INTS6 | integrator complex subunit 6 | -0.0276595 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0274461 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | -0.0272327 |
| CTBP2 | C-terminal binding protein 2 | -0.0271529 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0271387 |
| RCOR1 | REST corepressor 1 | -0.0269085 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.026716 |
| FBXO11 | F-box protein 11 | -0.0267043 |
| RYBP | RING1 and YY1 binding protein | -0.0263166 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0261704 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0256647 |
| ATP11A | ATPase, class VI, type 11A | -0.0255667 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0253928 |
| SPPL3 | signal peptide peptidase like 3 | -0.0252192 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0251929 |
| MICU1 | mitochondrial calcium uptake 1 | -0.0251293 |
| PHF3 | PHD finger protein 3 | -0.0250135 |
| SERTAD2 | SERTA domain containing 2 | -0.0248388 |
| SMAP1 | small ArfGAP 1 | -0.0246907 |
| SKP1 | S-phase kinase-associated protein 1 | -0.023711 |
| SBF2 | SET binding factor 2 | -0.0235502 |
| CHKA | choline kinase alpha | -0.02301 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0226525 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0225054 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0223956 |
| CLMP | CXADR-like membrane protein | -0.0219559 |
| UVRAG | UV radiation resistance associated | -0.0215139 |
| JAM3 | junctional adhesion molecule 3 | -0.0211765 |
| TFRC | transferrin receptor | -0.0211581 |
| SHISA3 | shisa family member 3 | -0.0211558 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0209922 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.020936 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0208557 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0203735 |
| UBAP2 | ubiquitin associated protein 2 | -0.0200526 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0200455 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0200233 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0198494 |
| HMGB1 | high mobility group box 1 | -0.0198375 |
| THBS1 | thrombospondin 1 | -0.0197721 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | -0.0192622 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | -0.0191781 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.018842 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0188311 |
| TMEM45A | transmembrane protein 45A | -0.0186911 |
| CLTC | clathrin, heavy chain (Hc) | -0.0186705 |
| FLNB | filamin B, beta | -0.0186198 |
| COL5A2 | collagen, type V, alpha 2 | -0.0184711 |
| IGF2 | insulin-like growth factor 2 | -0.0184529 |
| SNX14 | sorting nexin 14 | -0.0183763 |
| ATXN2 | ataxin 2 | -0.0183239 |
| IPO7 | importin 7 | -0.0183218 |
| ARHGAP19 | Rho GTPase activating protein 19 | -0.0182017 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0181858 |
| PRLR | prolactin receptor | -0.0181672 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0181607 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0180928 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0180696 |
| ADIPOR2 | adiponectin receptor 2 | -0.0180216 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0179958 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0179836 |
