| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cabozantinib (S-malate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cabozantinib (S-malate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | 0.140357 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0632443 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0564581 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0537043 |
| ADM | adrenomedullin | 0.0521278 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0486918 |
| HLA-A | major histocompatibility complex, class I, A | 0.0484072 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0434356 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0420377 |
| HLA-C | major histocompatibility complex, class I, C | 0.0400689 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0397287 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0395615 |
| AOPEP | aminopeptidase O (putative) | 0.0377621 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0375169 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0373413 |
| GPC6 | glypican 6 | 0.0372947 |
| RNF145 | ring finger protein 145 | 0.0371578 |
| FTL | ferritin, light polypeptide | 0.0365541 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.035417 |
| FAM13A | family with sequence similarity 13, member A | 0.0352281 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0351918 |
| XPO1 | exportin 1 | 0.0346753 |
| RPL35A | ribosomal protein L35a | 0.0346098 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0339769 |
| RAD51B | RAD51 paralog B | 0.033489 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0333049 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0328639 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0325762 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0324925 |
| FOXJ3 | forkhead box J3 | 0.0323631 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0320394 |
| APP | amyloid beta (A4) precursor protein | 0.0313186 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0312388 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0310726 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0306427 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0304989 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0300668 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.030019 |
| NAV2 | neuron navigator 2 | 0.029926 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0296598 |
| PRELID2 | PRELI domain containing 2 | 0.0295784 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0289194 |
| MED15 | mediator complex subunit 15 | 0.0289057 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0282302 |
| NRXN3 | neurexin 3 | 0.0282056 |
| PARD3 | par-3 family cell polarity regulator | 0.0280946 |
| COG5 | component of oligomeric golgi complex 5 | 0.0280344 |
| GSE1 | Gse1 coiled-coil protein | 0.0280008 |
| ZNF638 | zinc finger protein 638 | 0.0277557 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0275942 |
| NDRG1 | N-myc downstream regulated 1 | 0.027522 |
| GGT7 | gamma-glutamyltransferase 7 | 0.0274932 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0274804 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0268966 |
| KIF13A | kinesin family member 13A | 0.026894 |
| SETD5 | SET domain containing 5 | 0.0268082 |
| DST | dystonin | 0.0267175 |
| TGFB1 | transforming growth factor, beta 1 | 0.0265774 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0261975 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0261834 |
| RPL11 | ribosomal protein L11 | 0.0259782 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0259741 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.0258768 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.025862 |
| RPS19 | ribosomal protein S19 | 0.0257044 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0256714 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0252408 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0252205 |
| PGK1 | phosphoglycerate kinase 1 | 0.0251439 |
| VEGFA | vascular endothelial growth factor A | 0.0251214 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0249509 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0248261 |
| VMP1 | vacuole membrane protein 1 | 0.0245806 |
| FNIP1 | folliculin interacting protein 1 | 0.0245677 |
| PLEC | plectin | 0.0244011 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0244008 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0243813 |
| NF1 | neurofibromin 1 | 0.024361 |
| FMNL2 | formin-like 2 | 0.0241346 |
| OGA | O-GlcNAcase | 0.0239092 |
| WDR26 | WD repeat domain 26 | 0.0239027 |
| KIF16B | kinesin family member 16B | 0.0238644 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0237705 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0237505 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0237187 |
| B2M | beta-2-microglobulin | 0.0236556 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0235526 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0235439 |
| KYNU | kynureninase | 0.0235385 |
| SNX9 | sorting nexin 9 | 0.0234458 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0233431 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0232653 |
| MORF4L1 | mortality factor 4 like 1 | 0.0232353 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0230599 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0229399 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0228892 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0228392 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0227607 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0227437 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0227019 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.175609 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.1723 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.153186 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.143283 |
| FN1 | fibronectin 1 | -0.11681 |
| ENO1 | enolase 1, (alpha) | -0.11203 |
| TMSB10 | thymosin beta 10 | -0.105143 |
| LOX | lysyl oxidase | -0.0965609 |
| MT2A | metallothionein 2A | -0.0913957 |
| POTEF | POTE ankyrin domain family, member F | -0.0888068 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0840159 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0830533 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0812433 |
| LDHA | lactate dehydrogenase A | -0.0807401 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0770161 |
| UBC | ubiquitin C | -0.0734409 |
| MAP1B | microtubule-associated protein 1B | -0.0692474 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0662162 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0651879 |
| SDC4 | syndecan 4 | -0.0650742 |
| COL1A2 | collagen, type I, alpha 2 | -0.0636732 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0634943 |
| CALU | calumenin | -0.0629987 |
| TPM4 | tropomyosin 4 | -0.0627363 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0626222 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0617084 |
| CDH13 | cadherin 13 | -0.0612701 |
| IL6 | interleukin 6 | -0.0604721 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0589323 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.053479 |
| AHNAK | AHNAK nucleoprotein | -0.0534697 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0532383 |
| ANXA5 | annexin A5 | -0.0487349 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0487337 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.047887 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0475362 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0469086 |
| SEPTIN7 | septin 7 | -0.0466611 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0464743 |
| CLTC | clathrin, heavy chain (Hc) | -0.0463634 |
| CANX | calnexin | -0.0455498 |
| PTMA | prothymosin, alpha | -0.0436973 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0431739 |
| SPAG9 | sperm associated antigen 9 | -0.0428905 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0418633 |
| FAM3C | family with sequence similarity 3, member C | -0.040935 |
| HMGA2 | high mobility group AT-hook 2 | -0.0406311 |
| SEC24D | SEC24 family member D | -0.0404705 |
| VCL | vinculin | -0.0401215 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0398914 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0389487 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0380558 |
| SEC61G | Sec61 gamma subunit | -0.0373883 |
| CCNI | cyclin I | -0.0369725 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0369574 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0360097 |
| HDLBP | high density lipoprotein binding protein | -0.035777 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0356554 |
| TXNIP | thioredoxin interacting protein | -0.0350333 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0346246 |
| JUN | jun proto-oncogene | -0.0331517 |
| FLNB | filamin B, beta | -0.0329259 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0326961 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0323529 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0323189 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0319843 |
| CD44 | CD44 molecule (Indian blood group) | -0.0317177 |
| ZNF207 | zinc finger protein 207 | -0.031692 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0316619 |
| STK17A | serine/threonine kinase 17a | -0.0310132 |
| CDK6 | cyclin-dependent kinase 6 | -0.0304982 |
| MTPN | myotrophin | -0.0304897 |
| CALR | calreticulin | -0.0303674 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0302956 |
| MYO10 | myosin X | -0.0300781 |
| GNAS | GNAS complex locus | -0.0298319 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0296615 |
| CENPF | centromere protein F, 350/400kDa | -0.0290997 |
| TLN1 | talin 1 | -0.0289153 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.028855 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0286687 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0284987 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0284328 |
| TUBA1B | tubulin, alpha 1b | -0.0283915 |
| ECE1 | endothelin converting enzyme 1 | -0.0283034 |
| WTAP | Wilms tumor 1 associated protein | -0.027648 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0276148 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0274457 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.02734 |
| PKM | pyruvate kinase, muscle | -0.0271734 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0269248 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0265498 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0264113 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0259772 |
| CUL4B | cullin 4B | -0.0259613 |
| PRSS23 | protease, serine, 23 | -0.0257277 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0256584 |
| IPO7 | importin 7 | -0.0256141 |
| PTGES2 | prostaglandin E synthase 2 | -0.0254873 |
| MSN | moesin | -0.0254555 |
