| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cabozantinib (S-malate) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cabozantinib (S-malate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CEP250 | centrosomal protein 250kDa | 0.0835051 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0745025 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0682566 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0676504 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0658145 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0650354 |
| SETD5 | SET domain containing 5 | 0.0613249 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0593662 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0557644 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0534301 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0511938 |
| PTMA | prothymosin, alpha | 0.0505992 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0503241 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0499779 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0487574 |
| TBC1D5 | TBC1 domain family, member 5 | 0.047458 |
| GOLGA2 | golgin A2 | 0.0459662 |
| HLA-A | major histocompatibility complex, class I, A | 0.0449843 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0449565 |
| PCBP2 | poly(rC) binding protein 2 | 0.0445661 |
| HLA-B | major histocompatibility complex, class I, B | 0.0434277 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0419814 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0419612 |
| SNX14 | sorting nexin 14 | 0.0413449 |
| RPS3 | ribosomal protein S3 | 0.040635 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0401447 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0399683 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0398789 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0390456 |
| RNF145 | ring finger protein 145 | 0.0387897 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0382118 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.038174 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0377022 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0372838 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0370038 |
| MATR3 | matrin 3 | 0.036997 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0363386 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0363149 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0362676 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0362173 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0361582 |
| SRPK2 | SRSF protein kinase 2 | 0.036052 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0357246 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0344919 |
| CALR | calreticulin | 0.0344465 |
| HDGF | hepatoma-derived growth factor | 0.0343864 |
| OGA | O-GlcNAcase | 0.0343694 |
| NAV2 | neuron navigator 2 | 0.0342237 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0336985 |
| MAP1B | microtubule-associated protein 1B | 0.0330658 |
| RPS20 | ribosomal protein S20 | 0.0329217 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0327483 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0325127 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0324641 |
| INSIG1 | insulin induced gene 1 | 0.0318949 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0317908 |
| NUCB2 | nucleobindin 2 | 0.0316277 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0315727 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0312632 |
| CALU | calumenin | 0.0311344 |
| PFN1 | profilin 1 | 0.0310389 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0308352 |
| EXOC5 | exocyst complex component 5 | 0.0307988 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0307597 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0302334 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0301735 |
| DEK | DEK proto-oncogene | 0.0301169 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0298185 |
| NUP58 | nucleoporin 58 | 0.0296903 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0295356 |
| B2M | beta-2-microglobulin | 0.0294467 |
| USP37 | ubiquitin specific peptidase 37 | 0.0293908 |
| KIF2A | kinesin heavy chain member 2A | 0.0289048 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.028824 |
| PARD3 | par-3 family cell polarity regulator | 0.0287846 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0287799 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0287093 |
| SMAD3 | SMAD family member 3 | 0.0280567 |
| USP3 | ubiquitin specific peptidase 3 | 0.0276031 |
| XPO6 | exportin 6 | 0.0275197 |
| CCNY | cyclin Y | 0.0275 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0274331 |
| SMYD3 | SET and MYND domain containing 3 | 0.02742 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0272831 |
| ZNF609 | zinc finger protein 609 | 0.0271865 |
| RPS8 | ribosomal protein S8 | 0.0271475 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0270108 |
| TMEM41B | transmembrane protein 41B | 0.0269755 |
| MT2A | metallothionein 2A | 0.0269566 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0269528 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0268589 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0268583 |
| TPM3 | tropomyosin 3 | 0.026789 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0267397 |
| SET | SET nuclear proto-oncogene | 0.0262723 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0262375 |
| XPO1 | exportin 1 | 0.0260906 |
| HLTF | helicase-like transcription factor | 0.0259852 |
| HJURP | Holliday junction recognition protein | 0.0259833 |
| PDS5B | PDS5 cohesin associated factor B | 0.0258814 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.155915 |
| OSMR | oncostatin M receptor | -0.0984937 |
| CD44 | CD44 molecule (Indian blood group) | -0.0914519 |
| LDHA | lactate dehydrogenase A | -0.0845944 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0833244 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0759616 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0732748 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0730489 |
| VIM | vimentin | -0.0682074 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0678279 |
| VCL | vinculin | -0.0626134 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0610197 |
| HDAC9 | histone deacetylase 9 | -0.0605711 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0598963 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0561407 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0517718 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0510054 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0509291 |
| DST | dystonin | -0.0503044 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0498495 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0489614 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.048895 |
| FMN1 | formin 1 | -0.0471598 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0453087 |
| SLC36A4 | solute carrier family 36 (proton/amino acid symporter), member 4 | -0.0448026 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0438615 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0436878 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0428163 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0425873 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0417362 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0406017 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0403762 |
| HMGA2 | high mobility group AT-hook 2 | -0.0401312 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0386091 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0383455 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0380274 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.037064 |
| NF1 | neurofibromin 1 | -0.0366568 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0362447 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0360363 |
| LOC112694756 | uncharaterized LOC112694756 | -0.035725 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0353476 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0352666 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0347513 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0339379 |
| RPS25 | ribosomal protein S25 | -0.0339107 |
| ANKRD28 | ankyrin repeat domain 28 | -0.033339 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0333357 |
| INTS6 | integrator complex subunit 6 | -0.0332696 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0330306 |
| TPM4 | tropomyosin 4 | -0.0328434 |
| USP34 | ubiquitin specific peptidase 34 | -0.0319064 |
| NAV3 | neuron navigator 3 | -0.0318892 |
| ANXA2 | annexin A2 | -0.0318148 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.031717 |
| NALCN | sodium leak channel, non selective | -0.0314795 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0310716 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0309617 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0309217 |
| DIAPH3 | diaphanous-related formin 3 | -0.0305248 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0303608 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0302714 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0299639 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0298786 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0297993 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0296944 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0296162 |
| IL6ST | interleukin 6 signal transducer | -0.0294858 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0293844 |
| FERMT2 | fermitin family member 2 | -0.0292644 |
| FNIP1 | folliculin interacting protein 1 | -0.0290324 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0289826 |
| BRCA2 | breast cancer 2, early onset | -0.0280856 |
| RAB33B | RAB33B, member RAS oncogene family | -0.0278572 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0278258 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0277707 |
| RANBP17 | RAN binding protein 17 | -0.0275395 |
| WDR26 | WD repeat domain 26 | -0.0275103 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0274983 |
| ACER3 | alkaline ceramidase 3 | -0.0272937 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0271939 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0271183 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0268968 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0266283 |
| AHNAK | AHNAK nucleoprotein | -0.0265719 |
| FRYL | FRY-like | -0.0264476 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | -0.0261968 |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | -0.0261348 |
| ABI2 | abl-interactor 2 | -0.0260617 |
| POTEF | POTE ankyrin domain family, member F | -0.0260175 |
| NABP1 | nucleic acid binding protein 1 | -0.0259837 |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | -0.0259688 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0259053 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0257458 |
| DTNA | dystrobrevin, alpha | -0.0252329 |
| YIPF4 | Yip1 domain family, member 4 | -0.0250365 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0245641 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.024543 |
| ERBIN | erbb2 interacting protein | -0.02402 |
| KPNB1 | karyopherin (importin) beta 1 | -0.023914 |
