| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cabozantinib (S-malate) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cabozantinib (S-malate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.182615 |
| TNS3 | tensin 3 | 0.0648308 |
| NAV2 | neuron navigator 2 | 0.0642279 |
| HDAC4 | histone deacetylase 4 | 0.0625133 |
| CDH13 | cadherin 13 | 0.0499624 |
| ATXN1 | ataxin 1 | 0.0498097 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0487685 |
| AOPEP | aminopeptidase O (putative) | 0.0447372 |
| PLEC | plectin | 0.0430937 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0412313 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0404812 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0391012 |
| RUNX1 | runt-related transcription factor 1 | 0.0390734 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0375642 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0352142 |
| RAD51B | RAD51 paralog B | 0.034474 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0339234 |
| EXOC4 | exocyst complex component 4 | 0.0323966 |
| ACTG1 | actin gamma 1 | 0.0316747 |
| SPATA13 | spermatogenesis associated 13 | 0.0316619 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.0314873 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0314694 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0314161 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0304517 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0301389 |
| DST | dystonin | 0.0294693 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0293461 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0293105 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.029057 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0286049 |
| CMIP | c-Maf inducing protein | 0.028523 |
| KIZ | kizuna centrosomal protein | 0.0281198 |
| KRT18 | keratin 18, type I | 0.0267518 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0266922 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0259073 |
| ZNF638 | zinc finger protein 638 | 0.0258417 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | 0.0255651 |
| PROX1 | prospero homeobox 1 | 0.0253902 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0251875 |
| SMAD3 | SMAD family member 3 | 0.0243117 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0242463 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0234476 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0230605 |
| BPTF | bromodomain PHD finger transcription factor | 0.0229707 |
| APP | amyloid beta (A4) precursor protein | 0.0225544 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0225423 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0219333 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0218937 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0218248 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0216374 |
| FLNB | filamin B, beta | 0.0215886 |
| NEBL | nebulette | 0.0212471 |
| OGA | O-GlcNAcase | 0.0212054 |
| SETD5 | SET domain containing 5 | 0.0210479 |
| SMOC2 | SPARC related modular calcium binding 2 | 0.0210092 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0209331 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0208032 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0203169 |
| SMYD3 | SET and MYND domain containing 3 | 0.0203002 |
| KRT8 | keratin 8, type II | 0.0202292 |
| NONO | non-POU domain containing, octamer-binding | 0.0198812 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0198063 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0197338 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.0196716 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0192888 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0189427 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0188214 |
| SEPTIN9 | septin 9 | 0.0187922 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0186916 |
| SERINC5 | serine incorporator 5 | 0.0186232 |
| MSI2 | musashi RNA-binding protein 2 | 0.0185896 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0184888 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0183142 |
| VGLL4 | vestigial-like family member 4 | 0.0182176 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0179216 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0175751 |
| ITGB4 | integrin, beta 4 | 0.017559 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0174242 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0173312 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0171882 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0168935 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0168431 |
| ACTN4 | actinin, alpha 4 | 0.0167777 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0163964 |
| TRAF5 | TNF receptor-associated factor 5 | 0.0163635 |
| TNRC18 | trinucleotide repeat containing 18 | 0.01628 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0162219 |
| CDK13 | cyclin-dependent kinase 13 | 0.0160893 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0160394 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0159929 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.015759 |
| HDAC8 | histone deacetylase 8 | 0.0156824 |
| EPHB2 | EPH receptor B2 | 0.0154527 |
| CEP250 | centrosomal protein 250kDa | 0.0153882 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | 0.0153318 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0153104 |
| CUX1 | cut-like homeobox 1 | 0.0151722 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0150744 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0150692 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0149842 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.151007 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.123757 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0561237 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0447951 |
| VIM | vimentin | -0.0407161 |
| LDHA | lactate dehydrogenase A | -0.0397387 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0395911 |
| ENO1 | enolase 1, (alpha) | -0.0389324 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0381057 |
| PTMA | prothymosin, alpha | -0.0359012 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0356688 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0338863 |
| TUBA1B | tubulin, alpha 1b | -0.0331027 |
| RPS24 | ribosomal protein S24 | -0.0330587 |
| TMSB10 | thymosin beta 10 | -0.0324781 |
| ANLN | anillin, actin binding protein | -0.0288194 |
| NDRG1 | N-myc downstream regulated 1 | -0.028455 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0273327 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0270811 |
| HMGA1 | high mobility group AT-hook 1 | -0.0257879 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0257715 |
| RPLP1 | ribosomal protein, large, P1 | -0.0255986 |
| RPLP0 | ribosomal protein, large, P0 | -0.0244513 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.023601 |
| RPS8 | ribosomal protein S8 | -0.0231738 |
| POTEF | POTE ankyrin domain family, member F | -0.0229649 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0227983 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0227265 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0226223 |
| CBX3 | chromobox homolog 3 | -0.0223401 |
| S100A10 | S100 calcium binding protein A10 | -0.0212846 |
| TMEM123 | transmembrane protein 123 | -0.0211662 |
| RACK1 | receptor for activated C kinase 1 | -0.0207972 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0206564 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.019956 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0194818 |
| FTL | ferritin, light polypeptide | -0.0192612 |
| RPL12 | ribosomal protein L12 | -0.0192008 |
| PKM | pyruvate kinase, muscle | -0.0189424 |
| PFN1 | profilin 1 | -0.0180892 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0179402 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0172715 |
| HMGB1 | high mobility group box 1 | -0.0169076 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0168811 |
| ANXA2 | annexin A2 | -0.0168628 |
| MT2A | metallothionein 2A | -0.0167156 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0166772 |
| SNX9 | sorting nexin 9 | -0.01666 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0165973 |
| RPL7 | ribosomal protein L7 | -0.0165611 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0160532 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0159829 |
| DSPP | dentin sialophosphoprotein | -0.0159594 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0159562 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0158827 |
| ARF4 | ADP-ribosylation factor 4 | -0.0155992 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0155766 |
| TPI1 | triosephosphate isomerase 1 | -0.0154359 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0153818 |
| GNAS | GNAS complex locus | -0.0152805 |
| FOSL1 | FOS-like antigen 1 | -0.0151818 |
| RPS19 | ribosomal protein S19 | -0.0151515 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.015108 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0150112 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0149147 |
| H3-3B | H3.3 histone B | -0.014637 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0142054 |
| RPS5 | ribosomal protein S5 | -0.0141692 |
| IER3 | immediate early response 3 | -0.0139486 |
| CENPF | centromere protein F, 350/400kDa | -0.0137524 |
| RPS2 | ribosomal protein S2 | -0.0134751 |
| RPL5 | ribosomal protein L5 | -0.0132527 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0132043 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0131692 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0129562 |
| MORF4L2 | mortality factor 4 like 2 | -0.0129178 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0127734 |
| RBP1 | retinol binding protein 1, cellular | -0.0126596 |
| IPO7 | importin 7 | -0.0125036 |
| EZR | ezrin | -0.0124913 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0124637 |
| CCND1 | cyclin D1 | -0.012305 |
| KRT19 | keratin 19, type I | -0.0122135 |
| RYBP | RING1 and YY1 binding protein | -0.0122096 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0120672 |
| RPS25 | ribosomal protein S25 | -0.0117891 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0117678 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0117611 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.011683 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0116184 |
| TFRC | transferrin receptor | -0.011575 |
| KLF6 | Kruppel-like factor 6 | -0.0114683 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0113383 |
| SEPTIN7 | septin 7 | -0.0113299 |
| VCL | vinculin | -0.0112629 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0111619 |
| RPL27A | ribosomal protein L27a | -0.0111462 |
| RPS13 | ribosomal protein S13 | -0.0110974 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.01092 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.010766 |
