Cachexia Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Severe weight loss, wasting of muscle, loss of appetite, and general debility related to a chronic disease. (Human Phenotype Ontology, HP_0004326)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D002100
Similar Terms
Downloads & Tools

Genes

46 genes/proteins associated with the disease Cachexia from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
TNF tumor necrosis factor 2.88009
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.88009
ZFP36 ZFP36 ring finger protein 2.88009
GHRL ghrelin/obestatin prepropeptide 2.88009
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 2.88009
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.88009
IL6 interleukin 6 2.88009
CXCL8 chemokine (C-X-C motif) ligand 8 2.88009
CD27 CD27 molecule 2.88009
PTHLH parathyroid hormone-like hormone 2.88009
IL1B interleukin 1, beta 1.4583
CCL2 chemokine (C-C motif) ligand 2 1.37132
PPARA peroxisome proliferator-activated receptor alpha 1.33022
CCL3 chemokine (C-C motif) ligand 3 1.32935
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.32935
CCL5 chemokine (C-C motif) ligand 5 1.29533
IL10 interleukin 10 1.26856
ICAM1 intercellular adhesion molecule 1 1.26052
EDN1 endothelin 1 1.21271
CAT catalase 1.19999
CXCL10 chemokine (C-X-C motif) ligand 10 1.1977
NOS2 nitric oxide synthase 2, inducible 1.19146
COL3A1 collagen, type III, alpha 1 1.16368
IL1RN interleukin 1 receptor antagonist 1.16236
TIMP1 TIMP metallopeptidase inhibitor 1 1.13552
FABP4 fatty acid binding protein 4, adipocyte 1.13143
MMP3 matrix metallopeptidase 3 1.13041
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.1136
COL1A1 collagen, type I, alpha 1 1.10872
VCAM1 vascular cell adhesion molecule 1 1.10734
CALCA calcitonin-related polypeptide alpha 1.09681
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.09154
TGFB1 transforming growth factor, beta 1 1.09011
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.08868
IL1A interleukin 1, alpha 1.08019
IL18 interleukin 18 1.07983
IGF1 insulin-like growth factor 1 (somatomedin C) 1.06625
VEGFA vascular endothelial growth factor A 1.0637
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.059
SOD2 superoxide dismutase 2, mitochondrial 1.05461
LPL lipoprotein lipase 1.04978
NOS3 nitric oxide synthase 3 (endothelial cell) 1.04757
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.03641
IFNG interferon, gamma 1.02896
FN1 fibronectin 1 1.01966
MMP8 matrix metallopeptidase 8 1.01814