| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Canagliflozin (hemihydrate) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Canagliflozin (hemihydrate)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.112088 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0701909 |
| RPS12 | ribosomal protein S12 | 0.0581148 |
| VMP1 | vacuole membrane protein 1 | 0.0543863 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0517813 |
| SET | SET nuclear proto-oncogene | 0.0453856 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | 0.0447038 |
| EFNA5 | ephrin-A5 | 0.0442844 |
| HMGB2 | high mobility group box 2 | 0.0438067 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0424539 |
| ENO1 | enolase 1, (alpha) | 0.0413175 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0409028 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0385465 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0361295 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0360793 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0349966 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0346203 |
| RPS3 | ribosomal protein S3 | 0.0321101 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0318403 |
| PNN | pinin, desmosome associated protein | 0.0318192 |
| RPS7 | ribosomal protein S7 | 0.031817 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0308548 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0308176 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0303857 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0297206 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.029186 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0291794 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0290462 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0289858 |
| SOX2 | SRY (sex determining region Y)-box 2 | 0.0282339 |
| NUP58 | nucleoporin 58 | 0.0277488 |
| SNX3 | sorting nexin 3 | 0.0275134 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0273784 |
| ZNF608 | zinc finger protein 608 | 0.0259023 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0257934 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0256983 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0256865 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0256268 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0251768 |
| ZNF146 | zinc finger protein 146 | 0.0251547 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0248193 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0242028 |
| RPS2 | ribosomal protein S2 | 0.0238021 |
| URI1 | URI1, prefoldin-like chaperone | 0.0234078 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0231101 |
| CDH18 | cadherin 18, type 2 | 0.0228865 |
| FHIT | fragile histidine triad | 0.0228003 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0224762 |
| TMF1 | TATA element modulatory factor 1 | 0.02243 |
| HHIP | hedgehog interacting protein | 0.0222718 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0222123 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0221832 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0220756 |
| TOX | thymocyte selection-associated high mobility group box | 0.0219966 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.0214974 |
| MATR3 | matrin 3 | 0.0212858 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0211745 |
| AGO4 | argonaute RISC catalytic component 4 | 0.020889 |
| KIF5B | kinesin family member 5B | 0.0208864 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0208539 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0208334 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.020659 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0206201 |
| NXN | nucleoredoxin | 0.020568 |
| CBX3 | chromobox homolog 3 | 0.0204728 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0203754 |
| UBE2J2 | ubiquitin-conjugating enzyme E2, J2 | 0.0200769 |
| RAD51B | RAD51 paralog B | 0.0200275 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | 0.0199998 |
| SMAD4 | SMAD family member 4 | 0.0199134 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0199023 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0198738 |
| RPL35 | ribosomal protein L35 | 0.0198563 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0197935 |
| TMED4 | transmembrane emp24 protein transport domain containing 4 | 0.0197533 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0197111 |
| RPL22L1 | ribosomal protein L22-like 1 | 0.0196803 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0196797 |
| RYK | receptor-like tyrosine kinase | 0.0192559 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0192273 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0191436 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0191377 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0190736 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0190117 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0189664 |
| RPL27A | ribosomal protein L27a | 0.0188586 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0186104 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0185676 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0183881 |
| KMT5B | lysine methyltransferase 5B | 0.018388 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | 0.0183757 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0181626 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.0180123 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) | 0.0179977 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.017962 |
| ITGA6 | integrin, alpha 6 | 0.0179597 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0178596 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0178471 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0178254 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0178252 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.379535 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.148802 |
| ACTG1 | actin gamma 1 | -0.118507 |
| TENM3 | teneurin transmembrane protein 3 | -0.0844274 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.073314 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0681849 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0660866 |
| TMSB10 | thymosin beta 10 | -0.0632012 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0627178 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0618721 |
| RPL28 | ribosomal protein L28 | -0.0611441 |
| DEK | DEK proto-oncogene | -0.0571653 |
| SMYD3 | SET and MYND domain containing 3 | -0.0566496 |
| UBC | ubiquitin C | -0.0564686 |
| GNAS | GNAS complex locus | -0.0563284 |
| LOC112694756 | uncharaterized LOC112694756 | -0.055671 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0547475 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.054391 |
| RPL34 | ribosomal protein L34 | -0.0520112 |
| RPS6 | ribosomal protein S6 | -0.0503731 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0499178 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.049315 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0489845 |
| RPS19 | ribosomal protein S19 | -0.0487539 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0484466 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0481909 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0474659 |
| RPL35A | ribosomal protein L35a | -0.0452695 |
| RPLP1 | ribosomal protein, large, P1 | -0.0436295 |
| RPS11 | ribosomal protein S11 | -0.0434886 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0433533 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0433355 |
| RIGI | RNA sensor RIG-I | -0.0424475 |
| RPS4X | ribosomal protein S4, X-linked | -0.0421818 |
| MLIP | muscular LMNA-interacting protein | -0.0415601 |
| NFIA | nuclear factor I/A | -0.0415389 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0409328 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0406866 |
| FMNL2 | formin-like 2 | -0.0404856 |
| AUTS2 | autism susceptibility candidate 2 | -0.0402816 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0395612 |
| YBX1 | Y box binding protein 1 | -0.0392405 |
| MED13 | mediator complex subunit 13 | -0.0390905 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0378478 |
| TPD52 | tumor protein D52 | -0.0375708 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0372049 |
| RPL8 | ribosomal protein L8 | -0.0371728 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0369848 |
| H1-0 | H1.0 linker histone | -0.0369703 |
| FBXO11 | F-box protein 11 | -0.0360484 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0359897 |
| EGR1 | early growth response 1 | -0.0359004 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0357637 |
| TCF12 | transcription factor 12 | -0.0349935 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0341342 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0340361 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0335849 |
| S100A10 | S100 calcium binding protein A10 | -0.0333972 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0329915 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0328081 |
| QKI | QKI, KH domain containing, RNA binding | -0.032588 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0324483 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0319392 |
| RPS29 | ribosomal protein S29 | -0.0318822 |
| RPS21 | ribosomal protein S21 | -0.0318637 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.031789 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0313215 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0311604 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0303114 |
| HDLBP | high density lipoprotein binding protein | -0.0302706 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0300899 |
| RPL4 | ribosomal protein L4 | -0.0300213 |
| RPS15 | ribosomal protein S15 | -0.0300193 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0295944 |
| PKM | pyruvate kinase, muscle | -0.0295387 |
| FOXO3 | forkhead box O3 | -0.0294858 |
| CDK12 | cyclin-dependent kinase 12 | -0.0293803 |
| DST | dystonin | -0.0292076 |
| TXNRD1 | thioredoxin reductase 1 | -0.0290872 |
| SNX14 | sorting nexin 14 | -0.0290602 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0289678 |
| ADAR | adenosine deaminase, RNA-specific | -0.0289216 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0289042 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0288298 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.028787 |
| RHOA | ras homolog family member A | -0.0287373 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0284643 |
| RPL19 | ribosomal protein L19 | -0.0279505 |
| HMGB1 | high mobility group box 1 | -0.027636 |
| PGK1 | phosphoglycerate kinase 1 | -0.0275194 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0273373 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0270178 |
| RPL38 | ribosomal protein L38 | -0.0268396 |
| RBM39 | RNA binding motif protein 39 | -0.0264418 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0262441 |
| NGLY1 | N-glycanase 1 | -0.0261091 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0260339 |
| RPS24 | ribosomal protein S24 | -0.0260291 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0257792 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0257091 |
