| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Canagliflozin (hemihydrate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Canagliflozin (hemihydrate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0753172 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0451052 |
| SERINC5 | serine incorporator 5 | 0.0449158 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0392507 |
| ZNF292 | zinc finger protein 292 | 0.0373793 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0358013 |
| LIMA1 | LIM domain and actin binding 1 | 0.0356558 |
| RNF149 | ring finger protein 149 | 0.0346781 |
| FNIP2 | folliculin interacting protein 2 | 0.033358 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0322327 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0320195 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0306216 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0302335 |
| RPS6 | ribosomal protein S6 | 0.0289825 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0284772 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0282687 |
| HMGB2 | high mobility group box 2 | 0.027788 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0273687 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0265596 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0254195 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0251562 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0245383 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0237798 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0237693 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0232679 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0227859 |
| KLHL24 | kelch-like family member 24 | 0.0227238 |
| RPS3 | ribosomal protein S3 | 0.0223451 |
| SET | SET nuclear proto-oncogene | 0.0222609 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0220579 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0220281 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0219885 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0219747 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0218545 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.021614 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0214912 |
| PTMA | prothymosin, alpha | 0.0211591 |
| EREG | epiregulin | 0.0210063 |
| FAT1 | FAT atypical cadherin 1 | 0.0209295 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0204447 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | 0.0200967 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.020061 |
| TMEM51 | transmembrane protein 51 | 0.0200247 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0200084 |
| KLF6 | Kruppel-like factor 6 | 0.0199334 |
| DENND4C | DENN/MADD domain containing 4C | 0.0198125 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.0195299 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0191427 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0190074 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0189976 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0189378 |
| CDK19 | cyclin-dependent kinase 19 | 0.0187081 |
| STK24 | serine/threonine kinase 24 | 0.0183781 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | 0.0183012 |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 | 0.0182921 |
| SYF2 | SYF2 pre-mRNA-splicing factor | 0.0182633 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0179206 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0179147 |
| DNM2 | dynamin 2 | 0.0178833 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0178274 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0176709 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0174664 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0172711 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0172209 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0171619 |
| TPR | translocated promoter region, nuclear basket protein | 0.0171257 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) | 0.0171108 |
| TPM3 | tropomyosin 3 | 0.017076 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0170246 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0170054 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0168904 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0168794 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0167534 |
| DSTN | destrin (actin depolymerizing factor) | 0.0166898 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0166537 |
| CREBRF | CREB3 regulatory factor | 0.0165099 |
| MAVS | mitochondrial antiviral signaling protein | 0.016449 |
| RPL12 | ribosomal protein L12 | 0.0164171 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0163986 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.016289 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.016212 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0161132 |
| USP34 | ubiquitin specific peptidase 34 | 0.0160698 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0159026 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0158196 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0158004 |
| CLSTN1 | calsyntenin 1 | 0.0156686 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0156659 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0156545 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.015642 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0155823 |
| STAG2 | stromal antigen 2 | 0.0155576 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0155482 |
| GPATCH8 | G patch domain containing 8 | 0.0154908 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0154382 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0153422 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0152835 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 0.0151479 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.01513 |
| MKRN1 | makorin ring finger protein 1 | 0.0150823 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.185819 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.17106 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.150965 |
| EGR1 | early growth response 1 | -0.135026 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.133832 |
| RUNX1 | runt-related transcription factor 1 | -0.108634 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.107822 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.106689 |
| RIGI | RNA sensor RIG-I | -0.0979062 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0957214 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0907341 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0894894 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0787583 |
| EPHB2 | EPH receptor B2 | -0.0777278 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0750728 |
| GOLGB1 | golgin B1 | -0.0740333 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0733823 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0708585 |
| ANXA2 | annexin A2 | -0.0707006 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0706874 |
| UBC | ubiquitin C | -0.0687102 |
| HLA-B | major histocompatibility complex, class I, B | -0.0669613 |
| MX2 | MX dynamin-like GTPase 2 | -0.065132 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0641738 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0634775 |
| IRF1 | interferon regulatory factor 1 | -0.0602438 |
| FNDC3B | fibronectin type III domain containing 3B | -0.059926 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0587449 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0560665 |
| RRBP1 | ribosome binding protein 1 | -0.0559125 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.054116 |
| NDRG1 | N-myc downstream regulated 1 | -0.0536238 |
| EZR | ezrin | -0.0520536 |
| MORF4L2 | mortality factor 4 like 2 | -0.0515134 |
| PLSCR1 | phospholipid scramblase 1 | -0.049456 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0493765 |
| LYZ | lysozyme | -0.0489124 |
| PRKCA | protein kinase C, alpha | -0.0488204 |
| TRIM2 | tripartite motif containing 2 | -0.0487216 |
| SPATA13 | spermatogenesis associated 13 | -0.0479756 |
| AGR2 | anterior gradient 2 | -0.047277 |
| B3GALT5 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 | -0.0460749 |
| SP100 | SP100 nuclear antigen | -0.0455288 |
| MX1 | MX dynamin-like GTPase 1 | -0.0454831 |
| XAF1 | XIAP associated factor 1 | -0.0453069 |
| CANX | calnexin | -0.0452049 |
| ANXA1 | annexin A1 | -0.0447085 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0446062 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0446021 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0440899 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0440632 |
| MSI2 | musashi RNA-binding protein 2 | -0.0435965 |
| RNF213 | ring finger protein 213 | -0.0432572 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0432546 |
| ATXN1 | ataxin 1 | -0.0428999 |
| INTS6 | integrator complex subunit 6 | -0.0427629 |
| H1-0 | H1.0 linker histone | -0.0416498 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0416343 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0414781 |
| ITGA6 | integrin, alpha 6 | -0.0413366 |
| MCU | mitochondrial calcium uniporter | -0.0403734 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0397617 |
| LCN2 | lipocalin 2 | -0.0388404 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0384953 |
| CCNL1 | cyclin L1 | -0.0383699 |
| RAB7A | RAB7A, member RAS oncogene family | -0.036702 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.036552 |
| B2M | beta-2-microglobulin | -0.0364491 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0363728 |
| COG6 | component of oligomeric golgi complex 6 | -0.0361985 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0356689 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0356528 |
| ATP11A | ATPase, class VI, type 11A | -0.0353655 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0353549 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0352638 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0352037 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0350571 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0350319 |
| MECOM | MDS1 and EVI1 complex locus | -0.034815 |
| FOXP1 | forkhead box P1 | -0.0340202 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0339991 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0339002 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0334957 |
| MYO1E | myosin IE | -0.0329951 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0329359 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0326087 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0325049 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0324918 |
| JUN | jun proto-oncogene | -0.0324318 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0322904 |
| PERP | PERP, TP53 apoptosis effector | -0.0321156 |
| HM13 | histocompatibility (minor) 13 | -0.0320651 |
| AHNAK | AHNAK nucleoprotein | -0.0320175 |
| MEIS2 | Meis homeobox 2 | -0.0319771 |
| EFNB2 | ephrin-B2 | -0.0319163 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0318723 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0318161 |
| ZNRF3 | zinc and ring finger 3 | -0.0316809 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0316738 |
| UTRN | utrophin | -0.031653 |
