| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Canagliflozin (hemihydrate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Canagliflozin (hemihydrate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0831883 |
| CLU | clusterin | 0.0633943 |
| B2M | beta-2-microglobulin | 0.0613767 |
| SQSTM1 | sequestosome 1 | 0.0507746 |
| PTMA | prothymosin, alpha | 0.0493286 |
| KRT17 | keratin 17, type I | 0.041721 |
| HLA-E | major histocompatibility complex, class I, E | 0.0411589 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0387372 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0365326 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0349435 |
| SQLE | squalene epoxidase | 0.0339372 |
| RPS8 | ribosomal protein S8 | 0.0312618 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0308785 |
| MT2A | metallothionein 2A | 0.0304358 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0302465 |
| RPS12 | ribosomal protein S12 | 0.0290612 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.028255 |
| S100A6 | S100 calcium binding protein A6 | 0.027969 |
| HLA-A | major histocompatibility complex, class I, A | 0.0275212 |
| FTL | ferritin, light polypeptide | 0.027253 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0265471 |
| S100A2 | S100 calcium binding protein A2 | 0.026078 |
| ENO1 | enolase 1, (alpha) | 0.0257484 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0254305 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0245848 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0245143 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0238513 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.0234608 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0226526 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.022142 |
| RPS3 | ribosomal protein S3 | 0.021828 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0216855 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0209718 |
| GOLGA4 | golgin A4 | 0.0209688 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0209412 |
| FLNA | filamin A, alpha | 0.0206187 |
| VMP1 | vacuole membrane protein 1 | 0.0205798 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0204662 |
| IGF2 | insulin-like growth factor 2 | 0.0199542 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 0.0194311 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0192761 |
| RPS7 | ribosomal protein S7 | 0.0189846 |
| CHMP5 | charged multivesicular body protein 5 | 0.018849 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0186067 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0183964 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0182654 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0181708 |
| RPS27 | ribosomal protein S27 | 0.0176782 |
| ANGPTL4 | angiopoietin-like 4 | 0.0174623 |
| NECTIN1 | nectin cell adhesion molecule 1 | 0.0173067 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0169298 |
| RPL21 | ribosomal protein L21 | 0.0169089 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0168558 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0166415 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0164239 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0163667 |
| YBX3 | Y box binding protein 3 | 0.0161177 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0161011 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0160898 |
| RNF145 | ring finger protein 145 | 0.0159431 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0156563 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0154072 |
| SET | SET nuclear proto-oncogene | 0.0153785 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0152104 |
| RACK1 | receptor for activated C kinase 1 | 0.015182 |
| GOLGA2 | golgin A2 | 0.0151169 |
| EGR1 | early growth response 1 | 0.0149789 |
| TBC1D10A | TBC1 domain family, member 10A | 0.0149499 |
| RPLP2 | ribosomal protein, large, P2 | 0.0148755 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0146629 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0145607 |
| PLK2 | polo-like kinase 2 | 0.0145113 |
| RPLP0 | ribosomal protein, large, P0 | 0.0144967 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0143116 |
| RPL18 | ribosomal protein L18 | 0.0142516 |
| HYOU1 | hypoxia up-regulated 1 | 0.0142491 |
| CSTB | cystatin B (stefin B) | 0.0141619 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0141502 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0140306 |
| RPL12 | ribosomal protein L12 | 0.0139882 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0139693 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0138687 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0138503 |
| CAMLG | calcium modulating ligand | 0.0137442 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0137176 |
| CAVIN1 | caveolae associated protein 1 | 0.0136845 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0135416 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.0135203 |
| SLK | STE20-like kinase | 0.0135186 |
| MT1E | metallothionein 1E | 0.013384 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0131801 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0131747 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0131386 |
| RPL37 | ribosomal protein L37 | 0.0129484 |
| RPS13 | ribosomal protein S13 | 0.0128497 |
| SNX3 | sorting nexin 3 | 0.0128451 |
| CREBRF | CREB3 regulatory factor | 0.0128066 |
| YTHDC1 | YTH domain containing 1 | 0.0127483 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.0126293 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0126173 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.19716 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.183914 |
| FLNB | filamin B, beta | -0.168784 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.164627 |
| AHNAK | AHNAK nucleoprotein | -0.14593 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.135573 |
| DPYD | dihydropyrimidine dehydrogenase | -0.116696 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.107555 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0864469 |
| ASPH | aspartate beta-hydroxylase | -0.0752824 |
| PTK2 | protein tyrosine kinase 2 | -0.0689263 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0686838 |
| MTSS1 | metastasis suppressor 1 | -0.067019 |
| CD44 | CD44 molecule (Indian blood group) | -0.0668173 |
| SULF1 | sulfatase 1 | -0.0665471 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0662663 |
| PODXL | podocalyxin-like | -0.0611522 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0606998 |
| RBM39 | RNA binding motif protein 39 | -0.0603546 |
| MYOF | myoferlin | -0.0589606 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0583759 |
| EMP1 | epithelial membrane protein 1 | -0.0567996 |
| POTEF | POTE ankyrin domain family, member F | -0.05667 |
| RIN2 | Ras and Rab interactor 2 | -0.0548987 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0543676 |
| RAI14 | retinoic acid induced 14 | -0.054336 |
| LMO7 | LIM domain 7 | -0.0543222 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0528993 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0527952 |
| PGK1 | phosphoglycerate kinase 1 | -0.0523904 |
| MYO10 | myosin X | -0.0511712 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0508229 |
| BLCAP | bladder cancer associated protein | -0.0505577 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0501267 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0497642 |
| RASAL2 | RAS protein activator like 2 | -0.0492792 |
| OSMR | oncostatin M receptor | -0.0488899 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0484612 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0484592 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0481987 |
| S100A10 | S100 calcium binding protein A10 | -0.0481978 |
| H1-0 | H1.0 linker histone | -0.0475811 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0475274 |
| CUL4B | cullin 4B | -0.0472502 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0470074 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0469898 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.046699 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0459322 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0457566 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0454271 |
| MEF2A | myocyte enhancer factor 2A | -0.0449142 |
| KIAA1217 | KIAA1217 | -0.0446093 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.044255 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.043994 |
| CANX | calnexin | -0.0432347 |
| CDK6 | cyclin-dependent kinase 6 | -0.0432251 |
| MECOM | MDS1 and EVI1 complex locus | -0.0431669 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.043095 |
| PALLD | palladin, cytoskeletal associated protein | -0.0423509 |
| TMSB4X | thymosin beta 4, X-linked | -0.0421329 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0421145 |
| NEK7 | NIMA-related kinase 7 | -0.041731 |
| AOPEP | aminopeptidase O (putative) | -0.0416684 |
| FOXO1 | forkhead box O1 | -0.0409328 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0408999 |
| FOXP1 | forkhead box P1 | -0.0402021 |
| LOC112694756 | uncharaterized LOC112694756 | -0.039762 |
| PRELID2 | PRELI domain containing 2 | -0.0397212 |
| ACTN4 | actinin, alpha 4 | -0.0395574 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0394902 |
| AMOTL1 | angiomotin like 1 | -0.0386582 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0384342 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0375385 |
| NRG1 | neuregulin 1 | -0.0374246 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0373396 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0372581 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.036734 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0367019 |
| FNIP1 | folliculin interacting protein 1 | -0.0366321 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0364624 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0361031 |
| UBC | ubiquitin C | -0.0354607 |
| DST | dystonin | -0.0351273 |
| ITGA6 | integrin, alpha 6 | -0.0350007 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0344408 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0343724 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0340901 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0338693 |
| NAV2 | neuron navigator 2 | -0.033841 |
| UTRN | utrophin | -0.0336357 |
| SULF2 | sulfatase 2 | -0.0336351 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0335359 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.03351 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.033063 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0327105 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0324304 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0323366 |
| FN1 | fibronectin 1 | -0.0320813 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0316275 |
| EGFR | epidermal growth factor receptor | -0.0315907 |
