| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Canagliflozin (hemihydrate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Canagliflozin (hemihydrate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.11177 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0966648 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0914616 |
| HDAC9 | histone deacetylase 9 | 0.073697 |
| STC1 | stanniocalcin 1 | 0.0537383 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0483241 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0471752 |
| VEGFA | vascular endothelial growth factor A | 0.0452246 |
| CDK19 | cyclin-dependent kinase 19 | 0.0424965 |
| ADM | adrenomedullin | 0.0376603 |
| HLA-E | major histocompatibility complex, class I, E | 0.036529 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0362731 |
| JMJD1C | jumonji domain containing 1C | 0.035414 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0351307 |
| CREBRF | CREB3 regulatory factor | 0.0346087 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0333318 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0325547 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.030148 |
| GOLGA4 | golgin A4 | 0.0293363 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0277908 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0271974 |
| MSN | moesin | 0.0271519 |
| PLIN2 | perilipin 2 | 0.027051 |
| VIM | vimentin | 0.026985 |
| STC2 | stanniocalcin 2 | 0.0257879 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0257313 |
| PHF21A | PHD finger protein 21A | 0.0254742 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0253686 |
| PCBP2 | poly(rC) binding protein 2 | 0.0247688 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0243155 |
| VMP1 | vacuole membrane protein 1 | 0.0240596 |
| JUN | jun proto-oncogene | 0.0234782 |
| RND3 | Rho family GTPase 3 | 0.0233089 |
| ATP13A3 | ATPase type 13A3 | 0.0228398 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0227597 |
| TMEM14B | transmembrane protein 14B | 0.0226076 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0225827 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0225492 |
| MICU1 | mitochondrial calcium uptake 1 | 0.0223374 |
| SNX3 | sorting nexin 3 | 0.0222717 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0222256 |
| SEC24A | SEC24 family member A | 0.0222157 |
| EEA1 | early endosome antigen 1 | 0.0222029 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0221219 |
| BRD2 | bromodomain containing 2 | 0.0221091 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0220758 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0218811 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0218399 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0217923 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0217428 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0212373 |
| EGR1 | early growth response 1 | 0.0210497 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0208325 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0205944 |
| OFD1 | oral-facial-digital syndrome 1 | 0.019926 |
| EGFR | epidermal growth factor receptor | 0.0197273 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0196811 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.019622 |
| TMF1 | TATA element modulatory factor 1 | 0.019586 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | 0.0193028 |
| LYST | lysosomal trafficking regulator | 0.019249 |
| LOX | lysyl oxidase | 0.0192013 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.0191633 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0191321 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0189381 |
| MYO9A | myosin IXA | 0.0188644 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.018823 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0182051 |
| HMGA2 | high mobility group AT-hook 2 | 0.0182029 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0181377 |
| FNBP4 | formin binding protein 4 | 0.0180008 |
| COPA | coatomer protein complex, subunit alpha | 0.017919 |
| ZNF292 | zinc finger protein 292 | 0.0178626 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0176111 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.017411 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0173872 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0173444 |
| SERINC1 | serine incorporator 1 | 0.0170789 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0170585 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0170541 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0168515 |
| UBAP2 | ubiquitin associated protein 2 | 0.0167962 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0167784 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0166215 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0164485 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0164294 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0163066 |
| MCL1 | myeloid cell leukemia 1 | 0.01629 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0162712 |
| FLNB | filamin B, beta | 0.0161542 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0161111 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0160692 |
| ARRDC3 | arrestin domain containing 3 | 0.0160565 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0160502 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.0160071 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0158055 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.015792 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0157432 |
| RPL3 | ribosomal protein L3 | 0.0156763 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0156168 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.18544 |
| FN1 | fibronectin 1 | -0.145467 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.118635 |
| TMSB10 | thymosin beta 10 | -0.104018 |
| HLA-B | major histocompatibility complex, class I, B | -0.102795 |
| NAV2 | neuron navigator 2 | -0.100005 |
| CD44 | CD44 molecule (Indian blood group) | -0.0975842 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0961137 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0903533 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0862072 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0830516 |
| AHNAK | AHNAK nucleoprotein | -0.0747221 |
| PGK1 | phosphoglycerate kinase 1 | -0.0733699 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0710137 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0677289 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0662729 |
| BICC1 | BicC family RNA binding protein 1 | -0.0629353 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.060353 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0602813 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0566102 |
| SMAD3 | SMAD family member 3 | -0.0552138 |
| THBS1 | thrombospondin 1 | -0.054199 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0531861 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0529236 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0520319 |
| TNS3 | tensin 3 | -0.0519955 |
| ANXA2 | annexin A2 | -0.0505015 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0502594 |
| RPLP2 | ribosomal protein, large, P2 | -0.0484094 |
| RIGI | RNA sensor RIG-I | -0.0480887 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.047632 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0451737 |
| FRMD4A | FERM domain containing 4A | -0.0449122 |
| CENPF | centromere protein F, 350/400kDa | -0.0446142 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0442908 |
| RRBP1 | ribosome binding protein 1 | -0.0440698 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0434912 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0424007 |
| MKI67 | marker of proliferation Ki-67 | -0.0423375 |
| ANLN | anillin, actin binding protein | -0.0415324 |
| RNF213 | ring finger protein 213 | -0.0414899 |
| RTN4 | reticulon 4 | -0.0414716 |
| RPS24 | ribosomal protein S24 | -0.0414692 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0412346 |
| NAV1 | neuron navigator 1 | -0.0399573 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0398783 |
| RPL35A | ribosomal protein L35a | -0.0396137 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0385378 |
| QKI | QKI, KH domain containing, RNA binding | -0.0384751 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0383675 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0383549 |
| OSMR | oncostatin M receptor | -0.0383068 |
| MX1 | MX dynamin-like GTPase 1 | -0.0374953 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0374211 |
| RPL26 | ribosomal protein L26 | -0.0373697 |
| RPS6 | ribosomal protein S6 | -0.0370391 |
| TPM1 | tropomyosin 1 (alpha) | -0.0361107 |
| AFDN | afadin, adherens junction formation factor | -0.0359315 |
| RPL37A | ribosomal protein L37a | -0.0356572 |
| TUBB | tubulin, beta class I | -0.0354451 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0354167 |
| RBM39 | RNA binding motif protein 39 | -0.0353916 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0353885 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0350744 |
| DEK | DEK proto-oncogene | -0.035065 |
| RPL32 | ribosomal protein L32 | -0.0349677 |
| PKM | pyruvate kinase, muscle | -0.0344915 |
| RPL36 | ribosomal protein L36 | -0.0342658 |
| SPAG9 | sperm associated antigen 9 | -0.0340529 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0328226 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0327312 |
| LOXL2 | lysyl oxidase-like 2 | -0.0326425 |
| ARF4 | ADP-ribosylation factor 4 | -0.032255 |
| RPLP1 | ribosomal protein, large, P1 | -0.032082 |
| HLA-C | major histocompatibility complex, class I, C | -0.0314906 |
| RPS4X | ribosomal protein S4, X-linked | -0.031433 |
| DENND5A | DENN/MADD domain containing 5A | -0.0313694 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0311946 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0309476 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0303645 |
| RPL11 | ribosomal protein L11 | -0.0301774 |
| RPL19 | ribosomal protein L19 | -0.0299908 |
| TAPBP | TAP binding protein (tapasin) | -0.0297082 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0296994 |
| KLHL5 | kelch-like family member 5 | -0.0293927 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0293563 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.029353 |
| IER3 | immediate early response 3 | -0.0292273 |
| PHIP | pleckstrin homology domain interacting protein | -0.0290177 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0287701 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0287495 |
| RPL4 | ribosomal protein L4 | -0.0287072 |
| ADAR | adenosine deaminase, RNA-specific | -0.0285935 |
| PLSCR1 | phospholipid scramblase 1 | -0.0283085 |
| TXNRD1 | thioredoxin reductase 1 | -0.0282169 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0279463 |
| YBX1 | Y box binding protein 1 | -0.027848 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0270458 |
| ACTG1 | actin gamma 1 | -0.0270355 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0269058 |
