| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Canagliflozin perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Canagliflozin_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.113767 |
| VMP1 | vacuole membrane protein 1 | 0.0954945 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0808406 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0778071 |
| IFNGR1 | interferon gamma receptor 1 | 0.0676789 |
| SMAD3 | SMAD family member 3 | 0.062447 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0621842 |
| PHF3 | PHD finger protein 3 | 0.0615924 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.060631 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0573535 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0569924 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0554857 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0554139 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0533392 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0531477 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.051867 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0511497 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0510603 |
| KIF16B | kinesin family member 16B | 0.0507692 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0505818 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0504619 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0487821 |
| ERBIN | erbb2 interacting protein | 0.0482853 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0475428 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0438178 |
| RPS6 | ribosomal protein S6 | 0.0436505 |
| MSI2 | musashi RNA-binding protein 2 | 0.0434142 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0433238 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0432473 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0430709 |
| SBF2 | SET binding factor 2 | 0.0424817 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0421988 |
| RPL7 | ribosomal protein L7 | 0.0418019 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0417207 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0416061 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0415252 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0411475 |
| MLPH | melanophilin | 0.041046 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0409352 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0406464 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0403592 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0399926 |
| DIAPH1 | diaphanous-related formin 1 | 0.0398104 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.039024 |
| STK24 | serine/threonine kinase 24 | 0.0390228 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0387816 |
| SPATA13 | spermatogenesis associated 13 | 0.038276 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0371789 |
| RAD51B | RAD51 paralog B | 0.037102 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0369006 |
| ZNF148 | zinc finger protein 148 | 0.0367137 |
| PDS5B | PDS5 cohesin associated factor B | 0.0362537 |
| TOP1 | topoisomerase (DNA) I | 0.0355189 |
| VCL | vinculin | 0.0353838 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0352571 |
| MYO10 | myosin X | 0.0352474 |
| SLK | STE20-like kinase | 0.0349834 |
| TXNIP | thioredoxin interacting protein | 0.0348824 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0346697 |
| AHI1 | Abelson helper integration site 1 | 0.0346533 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0346513 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0337722 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0336572 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0335191 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0333089 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0326091 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0319823 |
| FAT1 | FAT atypical cadherin 1 | 0.0319289 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0316893 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0315597 |
| RBM26 | RNA binding motif protein 26 | 0.0315024 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0313965 |
| RBM33 | RNA binding motif protein 33 | 0.0312037 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0311648 |
| LONP2 | lon peptidase 2, peroxisomal | 0.031118 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0310427 |
| SET | SET nuclear proto-oncogene | 0.0310247 |
| MICU2 | mitochondrial calcium uptake 2 | 0.0305567 |
| NUMB | numb homolog (Drosophila) | 0.0301805 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.029912 |
| MYO5B | myosin VB | 0.0299094 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0297059 |
| SP3 | Sp3 transcription factor | 0.0296775 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0296305 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0295393 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0292093 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0287956 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0287766 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0285689 |
| CUL3 | cullin 3 | 0.0283974 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0283543 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0282253 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0281937 |
| USP15 | ubiquitin specific peptidase 15 | 0.0279861 |
| MED13L | mediator complex subunit 13-like | 0.0275137 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0273985 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.0272428 |
| PRKCE | protein kinase C, epsilon | 0.0271728 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0270418 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0270354 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.141117 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0989791 |
| PERP | PERP, TP53 apoptosis effector | -0.0873106 |
| HLA-B | major histocompatibility complex, class I, B | -0.0834366 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0817599 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0790179 |
| EGR1 | early growth response 1 | -0.0789896 |
| EZR | ezrin | -0.0765046 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0717799 |
| XAF1 | XIAP associated factor 1 | -0.0701305 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0656338 |
| SQSTM1 | sequestosome 1 | -0.0642586 |
| MT2A | metallothionein 2A | -0.0638214 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0598791 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0568574 |
| IRF1 | interferon regulatory factor 1 | -0.0552858 |
| ABLIM1 | actin binding LIM protein 1 | -0.0549615 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0512904 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0500888 |
| S100A10 | S100 calcium binding protein A10 | -0.0490418 |
| PTMA | prothymosin, alpha | -0.0490208 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0483406 |
| EFNB2 | ephrin-B2 | -0.0481877 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0473219 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0462622 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0437375 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0430546 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0430391 |
| HLA-E | major histocompatibility complex, class I, E | -0.0429878 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0427413 |
| ANXA2 | annexin A2 | -0.0425355 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0396487 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0394493 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0390895 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0385917 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0379701 |
| MT1X | metallothionein 1X | -0.0377859 |
| JUN | jun proto-oncogene | -0.0372533 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0369104 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0366573 |
| KRT19 | keratin 19, type I | -0.0364662 |
| VDAC1 | voltage-dependent anion channel 1 | -0.036298 |
| B2M | beta-2-microglobulin | -0.0362503 |
| AGR2 | anterior gradient 2 | -0.0354 |
| LMO7 | LIM domain 7 | -0.0352323 |
| ENO1 | enolase 1, (alpha) | -0.0348147 |
| HLA-A | major histocompatibility complex, class I, A | -0.0341659 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0338407 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0338097 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.033667 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0336139 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0326572 |
| NUCB2 | nucleobindin 2 | -0.0322654 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0314849 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0313714 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0311561 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0305397 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0303564 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0303171 |
| H1-0 | H1.0 linker histone | -0.0300008 |
| HM13 | histocompatibility (minor) 13 | -0.0297576 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0293605 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0293479 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0292219 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0290126 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.028913 |
| WDR45B | WD repeat domain 45B | -0.0284533 |
| NCKAP5 | NCK-associated protein 5 | -0.0284 |
| AHNAK | AHNAK nucleoprotein | -0.0279566 |
| EHF | ets homologous factor | -0.0278152 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0276379 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0275959 |
| POTEF | POTE ankyrin domain family, member F | -0.0275705 |
| CENPF | centromere protein F, 350/400kDa | -0.0272838 |
| APOL1 | apolipoprotein L, 1 | -0.026984 |
| HBP1 | HMG-box transcription factor 1 | -0.0269148 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0267418 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) | -0.0266345 |
| CTSD | cathepsin D | -0.0266209 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0266093 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0264641 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0261786 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0258919 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0257804 |
| UBE4A | ubiquitination factor E4A | -0.0256929 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0256345 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.025604 |
| FBXO32 | F-box protein 32 | -0.0251578 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0250842 |
| TPM4 | tropomyosin 4 | -0.0249296 |
| LCN2 | lipocalin 2 | -0.0249247 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0246145 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0245731 |
| GPX2 | glutathione peroxidase 2 | -0.0243914 |
| TFG | TRK-fused gene | -0.0238777 |
| ARF4 | ADP-ribosylation factor 4 | -0.0237831 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0237356 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0236119 |
| TMSB10 | thymosin beta 10 | -0.0235591 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.023442 |
