| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Canagliflozin perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Canagliflozin_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.129348 |
| BCL2L1 | BCL2-like 1 | 0.0827621 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0813142 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0809812 |
| MSN | moesin | 0.0730726 |
| FOXO1 | forkhead box O1 | 0.0714211 |
| MCL1 | myeloid cell leukemia 1 | 0.0580261 |
| MYOF | myoferlin | 0.05559 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0555252 |
| PLEC | plectin | 0.0533282 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0531714 |
| ITGA6 | integrin, alpha 6 | 0.0505276 |
| PLAT | plasminogen activator, tissue | 0.0467735 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0450854 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0436772 |
| TGM2 | transglutaminase 2 | 0.0408203 |
| YBX3 | Y box binding protein 3 | 0.0389056 |
| NEK7 | NIMA-related kinase 7 | 0.0380186 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0379257 |
| SULF1 | sulfatase 1 | 0.0378889 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0376478 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0370288 |
| AFAP1 | actin filament associated protein 1 | 0.0365897 |
| PRELID2 | PRELI domain containing 2 | 0.0365062 |
| ASPH | aspartate beta-hydroxylase | 0.0359878 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.035966 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0355902 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0343468 |
| SMAD3 | SMAD family member 3 | 0.0343263 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0339725 |
| KIAA1217 | KIAA1217 | 0.0336929 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0314647 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0313156 |
| MYO10 | myosin X | 0.0310837 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0309953 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0306642 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.030641 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.030084 |
| CUL4B | cullin 4B | 0.0297362 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.029675 |
| CAPRIN2 | caprin family member 2 | 0.0291759 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0289153 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0287307 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0285224 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0285153 |
| ARRDC3 | arrestin domain containing 3 | 0.0283476 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0278897 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0271085 |
| DOK5 | docking protein 5 | 0.0270967 |
| ANXA11 | annexin A11 | 0.0268158 |
| RBM39 | RNA binding motif protein 39 | 0.0266142 |
| RNF19B | ring finger protein 19B | 0.0263046 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0262075 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0259496 |
| CLIC4 | chloride intracellular channel 4 | 0.0253368 |
| PODXL | podocalyxin-like | 0.0245838 |
| IGF2 | insulin-like growth factor 2 | 0.0243698 |
| BLCAP | bladder cancer associated protein | 0.0243096 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0241365 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0239267 |
| ANLN | anillin, actin binding protein | 0.0236956 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0236618 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0235797 |
| PLEKHG5 | pleckstrin homology domain containing, family G (with RhoGef domain) member 5 | 0.0233589 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.023326 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.023239 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0231013 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0230511 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0227105 |
| SERINC3 | serine incorporator 3 | 0.0225534 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0224855 |
| CCNL1 | cyclin L1 | 0.0224508 |
| TXNIP | thioredoxin interacting protein | 0.0222578 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0222287 |
| RTN4 | reticulon 4 | 0.0221684 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0220209 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0214136 |
| SEPTIN9 | septin 9 | 0.02136 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0213143 |
| SEPTIN11 | septin 11 | 0.0212517 |
| FOXP1 | forkhead box P1 | 0.0211634 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0211115 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0209909 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0209816 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0209039 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0208449 |
| OGA | O-GlcNAcase | 0.020842 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0203986 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.0199887 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0199351 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0199128 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0198903 |
| EZR | ezrin | 0.0198619 |
| NUP58 | nucleoporin 58 | 0.0198409 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0197929 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0197366 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0196957 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0196323 |
| FOSL1 | FOS-like antigen 1 | 0.0195973 |
| VMP1 | vacuole membrane protein 1 | 0.0194236 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.154966 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.14542 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.11289 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0920183 |
| LMO7 | LIM domain 7 | -0.0893327 |
| RPS6 | ribosomal protein S6 | -0.0669828 |
| CD44 | CD44 molecule (Indian blood group) | -0.0658646 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0624981 |
| RPS8 | ribosomal protein S8 | -0.0604219 |
| HM13 | histocompatibility (minor) 13 | -0.0562515 |
| INTS6 | integrator complex subunit 6 | -0.0556997 |
| RAI14 | retinoic acid induced 14 | -0.0542096 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0541774 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0537013 |
| MTSS1 | metastasis suppressor 1 | -0.0487467 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0478248 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0468139 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0466575 |
| RPLP1 | ribosomal protein, large, P1 | -0.0464219 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0459919 |
| STC1 | stanniocalcin 1 | -0.0454795 |
| CDK6 | cyclin-dependent kinase 6 | -0.0447335 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0443139 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0433704 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0433614 |
| GOLGB1 | golgin B1 | -0.0420539 |
| RASAL2 | RAS protein activator like 2 | -0.0418632 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0410638 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0391761 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0380925 |
| CANX | calnexin | -0.0380697 |
| PALLD | palladin, cytoskeletal associated protein | -0.0367976 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0366952 |
| GNAS | GNAS complex locus | -0.0366257 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.035001 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0345313 |
| HLA-E | major histocompatibility complex, class I, E | -0.0345243 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0337451 |
| PLS3 | plastin 3 | -0.0336215 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0335297 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0335027 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0330882 |
| EGFR | epidermal growth factor receptor | -0.032952 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0328771 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.0323569 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0320928 |
| HMGA2 | high mobility group AT-hook 2 | -0.0319581 |
| PRSS23 | protease, serine, 23 | -0.031207 |
| RPL39 | ribosomal protein L39 | -0.0311209 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.030653 |
| SQSTM1 | sequestosome 1 | -0.0301636 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0299787 |
| AHNAK | AHNAK nucleoprotein | -0.0296552 |
| RND3 | Rho family GTPase 3 | -0.0294614 |
| DST | dystonin | -0.0283697 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0283252 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0282414 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0280359 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0279839 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0275455 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0274147 |
| HLA-B | major histocompatibility complex, class I, B | -0.0272582 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0272154 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0270972 |
| MTDH | metadherin | -0.0269961 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0266755 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0264579 |
| CALB1 | calbindin 1, 28kDa | -0.0264122 |
| POTEF | POTE ankyrin domain family, member F | -0.0263712 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.025961 |
| S100A9 | S100 calcium binding protein A9 | -0.0253077 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0246181 |
| CUX1 | cut-like homeobox 1 | -0.0242156 |
| TRAM1 | translocation associated membrane protein 1 | -0.0241949 |
| JMJD1C | jumonji domain containing 1C | -0.024092 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0239415 |
| RPL12 | ribosomal protein L12 | -0.0238412 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0237583 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0233479 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0232415 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0228846 |
| ACTG1 | actin gamma 1 | -0.0227981 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0227942 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0224515 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0224284 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0223988 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa | -0.0223985 |
| FNIP1 | folliculin interacting protein 1 | -0.0221769 |
| ANXA1 | annexin A1 | -0.0221766 |
| ENO1 | enolase 1, (alpha) | -0.0218116 |
| RPLP2 | ribosomal protein, large, P2 | -0.0217843 |
| ASTN2 | astrotactin 2 | -0.0217643 |
| RPS27 | ribosomal protein S27 | -0.0215053 |
| FBXO11 | F-box protein 11 | -0.0214957 |
| HDLBP | high density lipoprotein binding protein | -0.0214476 |
| ATF4 | activating transcription factor 4 | -0.0210511 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0209555 |
| ATF6 | activating transcription factor 6 | -0.0209102 |
| TBCA | tubulin folding cofactor A | -0.0204447 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0202736 |
