| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Canagliflozin perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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89 genes differentially expressed following the Canagliflozin_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.373696 |
| SETD5 | SET domain containing 5 | 0.176861 |
| XPO1 | exportin 1 | 0.161626 |
| EGFR | epidermal growth factor receptor | 0.156475 |
| ACTG1 | actin gamma 1 | 0.136981 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.128082 |
| HELZ | helicase with zinc finger | 0.126397 |
| PTMA | prothymosin, alpha | 0.119057 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.110413 |
| PDE10A | phosphodiesterase 10A | 0.109533 |
| DSCAM | Down syndrome cell adhesion molecule | 0.109442 |
| RPS16 | ribosomal protein S16 | 0.105569 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0924292 |
| ENO1 | enolase 1, (alpha) | 0.0867907 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0823552 |
| ASPH | aspartate beta-hydroxylase | 0.078913 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0735654 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.068813 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0678439 |
| RPL11 | ribosomal protein L11 | 0.061536 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0611674 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0587991 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0586423 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0559005 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0532679 |
| RPL37 | ribosomal protein L37 | 0.0490377 |
| APP | amyloid beta (A4) precursor protein | 0.0422355 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0415973 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0403078 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0368956 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0355976 |
| JMJD1C | jumonji domain containing 1C | 0.0317589 |
| FTL | ferritin, light polypeptide | 0.0305517 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0297854 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0286471 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0270388 |
| ANXA2 | annexin A2 | 0.0255197 |
| FN1 | fibronectin 1 | 0.0226194 |
| LMO7 | LIM domain 7 | 0.0139215 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0130289 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.00877363 |
| RPS6 | ribosomal protein S6 | 0.00763041 |
| RPS21 | ribosomal protein S21 | 0.00739999 |
| H3-3B | H3.3 histone B | 0.00728264 |
| RPLP0 | ribosomal protein, large, P0 | 0.00162778 |
| RPS12 | ribosomal protein S12 | 8.12357E-4 |
| MEIS2 | Meis homeobox 2 | 3.01932E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | -0.24987 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.228485 |
| HMGA2 | high mobility group AT-hook 2 | -0.225008 |
| STC1 | stanniocalcin 1 | -0.145383 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.139569 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.139059 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.136241 |
| PRKCA | protein kinase C, alpha | -0.128161 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.116555 |
| RIGI | RNA sensor RIG-I | -0.114541 |
| RPL23 | ribosomal protein L23 | -0.113089 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0900709 |
| VIM | vimentin | -0.0861441 |
| MT2A | metallothionein 2A | -0.0816056 |
| RPL12 | ribosomal protein L12 | -0.0722908 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0687243 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0664459 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0650985 |
| COL5A2 | collagen, type V, alpha 2 | -0.0593599 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0572747 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0541933 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0537717 |
| RPLP1 | ribosomal protein, large, P1 | -0.0507885 |
| RUNX1 | runt-related transcription factor 1 | -0.0491748 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0471043 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0458298 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0416904 |
| RNF213 | ring finger protein 213 | -0.0416261 |
| NDRG1 | N-myc downstream regulated 1 | -0.0410052 |
| PKM | pyruvate kinase, muscle | -0.0402808 |
| CDH13 | cadherin 13 | -0.0395987 |
| RPLP2 | ribosomal protein, large, P2 | -0.0373844 |
| TMSB10 | thymosin beta 10 | -0.0369573 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0348933 |
| RPS8 | ribosomal protein S8 | -0.0334637 |
| LDHA | lactate dehydrogenase A | -0.0284931 |
| EFNA5 | ephrin-A5 | -0.0192486 |
| RPL5 | ribosomal protein L5 | -0.0137802 |
| GPC6 | glypican 6 | -0.013714 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0120131 |
| IER3 | immediate early response 3 | -0.00999 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.00338383 |
