| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Canagliflozin perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Canagliflozin_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0817614 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0692162 |
| ZNF292 | zinc finger protein 292 | 0.0624503 |
| EZR | ezrin | 0.0617437 |
| PDGFC | platelet derived growth factor C | 0.0538863 |
| CCNL1 | cyclin L1 | 0.0460449 |
| B2M | beta-2-microglobulin | 0.043632 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0429431 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.042486 |
| ECT2 | epithelial cell transforming 2 | 0.0405729 |
| UBC | ubiquitin C | 0.0396082 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0378032 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0376179 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0359936 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0357949 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0353698 |
| MT2A | metallothionein 2A | 0.0353395 |
| NUP58 | nucleoporin 58 | 0.0348991 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0338601 |
| TXNIP | thioredoxin interacting protein | 0.0338516 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0333426 |
| FAT1 | FAT atypical cadherin 1 | 0.0323805 |
| TFG | TRK-fused gene | 0.0321737 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0317498 |
| RPL3 | ribosomal protein L3 | 0.0313364 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0307746 |
| RPS19 | ribosomal protein S19 | 0.0304398 |
| RPL36 | ribosomal protein L36 | 0.0303813 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0296977 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0291083 |
| HELZ | helicase with zinc finger | 0.029064 |
| PFN1 | profilin 1 | 0.0287858 |
| RBM39 | RNA binding motif protein 39 | 0.0283305 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0275552 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0275333 |
| RPS11 | ribosomal protein S11 | 0.0266097 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0265839 |
| RPLP2 | ribosomal protein, large, P2 | 0.0264448 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0259495 |
| TJP1 | tight junction protein 1 | 0.0253019 |
| RPL7 | ribosomal protein L7 | 0.0251229 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0250095 |
| NDRG1 | N-myc downstream regulated 1 | 0.0250011 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0248109 |
| LOXL3 | lysyl oxidase-like 3 | 0.0241264 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0236781 |
| RPL21 | ribosomal protein L21 | 0.023627 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0231167 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0230274 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0229737 |
| BRD2 | bromodomain containing 2 | 0.0226206 |
| SERINC1 | serine incorporator 1 | 0.0225847 |
| ZNF608 | zinc finger protein 608 | 0.0225002 |
| PKM | pyruvate kinase, muscle | 0.0224701 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0224661 |
| CDK19 | cyclin-dependent kinase 19 | 0.0224622 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.022368 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0221581 |
| PLK2 | polo-like kinase 2 | 0.022112 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0216498 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0215976 |
| RPL18 | ribosomal protein L18 | 0.0214308 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0214155 |
| PDE8A | phosphodiesterase 8A | 0.0213946 |
| NCKAP1 | NCK-associated protein 1 | 0.0213775 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0213634 |
| APP | amyloid beta (A4) precursor protein | 0.0213295 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0213243 |
| YBX3 | Y box binding protein 3 | 0.0211872 |
| INSIG2 | insulin induced gene 2 | 0.0211441 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0210868 |
| TXNL1 | thioredoxin-like 1 | 0.0209568 |
| MRPL3 | mitochondrial ribosomal protein L3 | 0.0207562 |
| MORF4L1 | mortality factor 4 like 1 | 0.020735 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0207197 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0205277 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0204045 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.020332 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0202759 |
| DAPK3 | death-associated protein kinase 3 | 0.0202663 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.0201329 |
| BMP2K | BMP2 inducible kinase | 0.0197122 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0196287 |
| RACK1 | receptor for activated C kinase 1 | 0.0195998 |
| SFTPA2 | surfactant protein A2 | 0.019586 |
| HMGB2 | high mobility group box 2 | 0.0195207 |
| RHEB | Ras homolog enriched in brain | 0.0195188 |
| RPS2 | ribosomal protein S2 | 0.0194677 |
| RPL7A | ribosomal protein L7a | 0.0194419 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0192128 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0190829 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0188504 |
| CRY1 | cryptochrome circadian clock 1 | 0.0187738 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0187056 |
| SERF2 | small EDRK-rich factor 2 | 0.0185641 |
| ARRDC3 | arrestin domain containing 3 | 0.0185476 |
| RPL12 | ribosomal protein L12 | 0.0185282 |
| QKI | QKI, KH domain containing, RNA binding | 0.0185244 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | 0.0184642 |
| RPS12 | ribosomal protein S12 | 0.01842 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.168657 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.154353 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.150658 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.14259 |
| FOXP1 | forkhead box P1 | -0.131297 |
| PTMA | prothymosin, alpha | -0.120951 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.111063 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.102755 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0986937 |
| NBEA | neurobeachin | -0.0940971 |
| EGFR | epidermal growth factor receptor | -0.0834989 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0786318 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0728787 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.071579 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0644574 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0638263 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0608589 |
| EFNA5 | ephrin-A5 | -0.0601897 |
| NFIA | nuclear factor I/A | -0.0580454 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0579637 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.057126 |
| CCND1 | cyclin D1 | -0.0545822 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0540138 |
| SBF2 | SET binding factor 2 | -0.049781 |
| FLNB | filamin B, beta | -0.0458198 |
| JMJD1C | jumonji domain containing 1C | -0.0445288 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0441789 |
| GPHN | gephyrin | -0.0435271 |
| GLI3 | GLI family zinc finger 3 | -0.043068 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0405119 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0399289 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0396706 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0391385 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0378696 |
| CUX1 | cut-like homeobox 1 | -0.0371271 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0363893 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0362641 |
| ZNF438 | zinc finger protein 438 | -0.0359449 |
| HDLBP | high density lipoprotein binding protein | -0.0357806 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0357606 |
| TRERF1 | transcriptional regulating factor 1 | -0.034972 |
| RHBDD1 | rhomboid domain containing 1 | -0.0349125 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0346002 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0343022 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0335708 |
| RPL35A | ribosomal protein L35a | -0.0335099 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0334141 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0334027 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0332411 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0331922 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0330868 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0328866 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0323582 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0323569 |
| BPTF | bromodomain PHD finger transcription factor | -0.0322048 |
| PDE7B | phosphodiesterase 7B | -0.0316378 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0315504 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0314726 |
| PHF14 | PHD finger protein 14 | -0.0312985 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0310491 |
| AK1 | adenylate kinase 1 | -0.0308957 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0303019 |
| SMYD3 | SET and MYND domain containing 3 | -0.0300634 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0292539 |
| RPS24 | ribosomal protein S24 | -0.0290354 |
| EHBP1 | EH domain binding protein 1 | -0.0283964 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0283058 |
| INTS6 | integrator complex subunit 6 | -0.0281307 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0279117 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0278908 |
| TCF12 | transcription factor 12 | -0.0275906 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0274714 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0274322 |
| ATXN2 | ataxin 2 | -0.0274198 |
| NOP56 | NOP56 ribonucleoprotein | -0.0269436 |
| RPL9 | ribosomal protein L9 | -0.0266343 |
| GPATCH8 | G patch domain containing 8 | -0.0265203 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0264502 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0263706 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0262534 |
| FNBP4 | formin binding protein 4 | -0.0261295 |
| SEPTIN9 | septin 9 | -0.0261217 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | -0.026014 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0259477 |
| DIAPH2 | diaphanous-related formin 2 | -0.0259336 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0259287 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0258766 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0257978 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0257526 |
| DGKH | diacylglycerol kinase, eta | -0.0257238 |
| ASPH | aspartate beta-hydroxylase | -0.0256746 |
| RPLP1 | ribosomal protein, large, P1 | -0.0256662 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0256252 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0255104 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa | -0.025349 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.025057 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0248005 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0247378 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.024641 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0245948 |
