| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Canagliflozin perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Canagliflozin_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.103549 |
| RBM39 | RNA binding motif protein 39 | 0.0727546 |
| ZNF292 | zinc finger protein 292 | 0.0648493 |
| SETD5 | SET domain containing 5 | 0.0621525 |
| MSN | moesin | 0.0590413 |
| CAPRIN2 | caprin family member 2 | 0.0569504 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0560432 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0497796 |
| MT2A | metallothionein 2A | 0.0487445 |
| ATP13A3 | ATPase type 13A3 | 0.0476485 |
| MCL1 | myeloid cell leukemia 1 | 0.0470104 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0442957 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | 0.042447 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.041777 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0412124 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.040781 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0402724 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.039477 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.038927 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0388504 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0368436 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0363821 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0351808 |
| RPL37A | ribosomal protein L37a | 0.0340551 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0339628 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.033786 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0336671 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0329834 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0327911 |
| PRELID2 | PRELI domain containing 2 | 0.0327361 |
| FOXJ3 | forkhead box J3 | 0.032328 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0322638 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0322453 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0320559 |
| WDR43 | WD repeat domain 43 | 0.0320352 |
| ASPH | aspartate beta-hydroxylase | 0.0318398 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0317407 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0317087 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0315201 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0307872 |
| YAP1 | Yes-associated protein 1 | 0.0306758 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.030385 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0302855 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.030194 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0301817 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0297218 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0296392 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0295639 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0292713 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0288747 |
| CALU | calumenin | 0.0288274 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0285372 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0284372 |
| MAP1B | microtubule-associated protein 1B | 0.0283498 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0283387 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0280224 |
| KIAA1958 | KIAA1958 | 0.0279484 |
| DTNA | dystrobrevin, alpha | 0.0276422 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0275515 |
| RANBP2 | RAN binding protein 2 | 0.0274166 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0272586 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0272438 |
| SEC24A | SEC24 family member A | 0.0271818 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0270158 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.0266763 |
| CDK17 | cyclin-dependent kinase 17 | 0.0266755 |
| SPAG9 | sperm associated antigen 9 | 0.0262532 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0262086 |
| RPL26 | ribosomal protein L26 | 0.0262083 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0261966 |
| FERMT2 | fermitin family member 2 | 0.0260992 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0260989 |
| SEPTIN2 | septin 2 | 0.0260766 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0256484 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.025504 |
| PDE10A | phosphodiesterase 10A | 0.0254901 |
| DENND4A | DENN/MADD domain containing 4A | 0.0254674 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.0253684 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0253583 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0253252 |
| ATXN1 | ataxin 1 | 0.0249854 |
| RPL37 | ribosomal protein L37 | 0.0247765 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0247504 |
| SNX13 | sorting nexin 13 | 0.0245515 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0245029 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0244288 |
| RPL19 | ribosomal protein L19 | 0.0244099 |
| CCNL1 | cyclin L1 | 0.0241839 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0241597 |
| NUP58 | nucleoporin 58 | 0.024108 |
| ARRDC3 | arrestin domain containing 3 | 0.0240007 |
| HSPA8 | heat shock 70kDa protein 8 | 0.023557 |
| PRKD1 | protein kinase D1 | 0.0233278 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0229913 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0228831 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0226425 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0226157 |
| RPL7A | ribosomal protein L7a | 0.0225732 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.0225484 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0224274 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.286825 |
| VIM | vimentin | -0.127189 |
| GNAS | GNAS complex locus | -0.0701813 |
| TMSB10 | thymosin beta 10 | -0.0644366 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0447042 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.039326 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0375508 |
| RPLP1 | ribosomal protein, large, P1 | -0.0363838 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0358627 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0343567 |
| MYO9A | myosin IXA | -0.0333458 |
| CANX | calnexin | -0.033026 |
| DEK | DEK proto-oncogene | -0.0326942 |
| SGO2 | shugoshin 2 | -0.0319516 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.031901 |
| HMGA2 | high mobility group AT-hook 2 | -0.0318276 |
| PHF3 | PHD finger protein 3 | -0.0315163 |
| R3HDM1 | R3H domain containing 1 | -0.0314657 |
| SQSTM1 | sequestosome 1 | -0.0308322 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0297234 |
| TAOK1 | TAO kinase 1 | -0.0296956 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0292303 |
| IGF2 | insulin-like growth factor 2 | -0.0291293 |
| TMEM263 | transmembrane protein 263 | -0.0287294 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0286983 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0282918 |
| PCNX4 | pecanex 4 | -0.0280666 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0277312 |
| SVIL | supervillin | -0.027388 |
| SFSWAP | splicing factor, suppressor of white-apricot family | -0.027318 |
| ARF1 | ADP-ribosylation factor 1 | -0.0271049 |
| TUBB | tubulin, beta class I | -0.0267222 |
| TMEM123 | transmembrane protein 123 | -0.0267057 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0266309 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0263496 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.026347 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0260145 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0258502 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0258391 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0257912 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0254723 |
| SDC4 | syndecan 4 | -0.0253293 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0252059 |
| RPL12 | ribosomal protein L12 | -0.0252007 |
| ZNF721 | zinc finger protein 721 | -0.0251675 |
| RNF213 | ring finger protein 213 | -0.0249966 |
| BSG | basigin (Ok blood group) | -0.0247571 |
| CDK12 | cyclin-dependent kinase 12 | -0.0243927 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0241817 |
| TOM1L2 | target of myb1-like 2 (chicken) | -0.0238617 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.0237932 |
| TBCA | tubulin folding cofactor A | -0.0237147 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0236486 |
| CAVIN1 | caveolae associated protein 1 | -0.0236141 |
| HDAC9 | histone deacetylase 9 | -0.0235986 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | -0.0235645 |
| CD44 | CD44 molecule (Indian blood group) | -0.0235603 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.02333 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0232779 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0229702 |
| ZNF217 | zinc finger protein 217 | -0.0228645 |
| SATB2 | SATB homeobox 2 | -0.0227944 |
| EGFR | epidermal growth factor receptor | -0.0227248 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0226755 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0226385 |
| HMGB1 | high mobility group box 1 | -0.0225946 |
| NIN | ninein (GSK3B interacting protein) | -0.0224582 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0224397 |
| AHNAK | AHNAK nucleoprotein | -0.0223127 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0222056 |
| MED13 | mediator complex subunit 13 | -0.022177 |
| REST | RE1-silencing transcription factor | -0.0221128 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0219241 |
| RIN2 | Ras and Rab interactor 2 | -0.0218642 |
| CCAR1 | cell division cycle and apoptosis regulator 1 | -0.0218024 |
| SEPTIN7 | septin 7 | -0.0216538 |
| ANXA1 | annexin A1 | -0.021545 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0214287 |
| TCF12 | transcription factor 12 | -0.0213227 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0210757 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0210591 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0209118 |
| TPM4 | tropomyosin 4 | -0.0206985 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0206311 |
| CBX3 | chromobox homolog 3 | -0.0205336 |
| FTL | ferritin, light polypeptide | -0.0205042 |
| RSF1 | remodeling and spacing factor 1 | -0.0204871 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0204746 |
| TUT4 | terminal uridylyl transferase 4 | -0.0204039 |
| EXOC4 | exocyst complex component 4 | -0.0203714 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0203264 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0202927 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0202718 |
| RPS8 | ribosomal protein S8 | -0.0202684 |
| NPR2 | natriuretic peptide receptor 2 | -0.0202426 |
| MICA | MHC class I polypeptide-related sequence A | -0.0201198 |
| ATXN2 | ataxin 2 | -0.0201045 |
| EFNA5 | ephrin-A5 | -0.0199894 |
| RPLP0 | ribosomal protein, large, P0 | -0.0199333 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0198864 |
