| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Canagliflozin perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Canagliflozin_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0870217 |
| NDRG1 | N-myc downstream regulated 1 | 0.0796359 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0750965 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.070596 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0697332 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0536103 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0464738 |
| FAM13A | family with sequence similarity 13, member A | 0.0450414 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0395185 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.037866 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0328308 |
| ZNF292 | zinc finger protein 292 | 0.0322635 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0314274 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0309038 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0306723 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0279245 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0278064 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0273332 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0267717 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0266349 |
| NUP58 | nucleoporin 58 | 0.026283 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0262558 |
| B2M | beta-2-microglobulin | 0.0262293 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0257666 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0253549 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0245838 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.024527 |
| PTK2 | protein tyrosine kinase 2 | 0.0244627 |
| INSIG2 | insulin induced gene 2 | 0.0244103 |
| HELZ | helicase with zinc finger | 0.0243692 |
| TPD52 | tumor protein D52 | 0.0242158 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.024166 |
| PCBP2 | poly(rC) binding protein 2 | 0.0238539 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0238394 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0233501 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0231471 |
| ANXA5 | annexin A5 | 0.0226045 |
| MYOF | myoferlin | 0.0224758 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0222478 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0215128 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0213633 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0209157 |
| FOSL1 | FOS-like antigen 1 | 0.0208249 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0201241 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0201052 |
| CADM1 | cell adhesion molecule 1 | 0.0199906 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0195201 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.01939 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.019146 |
| RAB1A | RAB1A, member RAS oncogene family | 0.019087 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0190417 |
| MYO1B | myosin IB | 0.0188573 |
| FMNL2 | formin-like 2 | 0.0186792 |
| XPO1 | exportin 1 | 0.0186511 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0185292 |
| PLIN2 | perilipin 2 | 0.0184645 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0181204 |
| CD109 | CD109 molecule | 0.0181101 |
| TFG | TRK-fused gene | 0.0180684 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0180449 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0179387 |
| WDR43 | WD repeat domain 43 | 0.0178323 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0178302 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0177979 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.017674 |
| PRELID2 | PRELI domain containing 2 | 0.0176044 |
| GOLGA4 | golgin A4 | 0.0172549 |
| ARRDC3 | arrestin domain containing 3 | 0.0172141 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0170346 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0169627 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.016827 |
| NOP58 | NOP58 ribonucleoprotein | 0.0165009 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.016438 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0164334 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0162506 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0161974 |
| NKTR | natural killer cell triggering receptor | 0.0161205 |
| DENND4C | DENN/MADD domain containing 4C | 0.0160152 |
| YAP1 | Yes-associated protein 1 | 0.0158607 |
| MCL1 | myeloid cell leukemia 1 | 0.0158349 |
| RYBP | RING1 and YY1 binding protein | 0.0156138 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0155485 |
| CCNL1 | cyclin L1 | 0.0154535 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0153585 |
| MSN | moesin | 0.0153456 |
| COG5 | component of oligomeric golgi complex 5 | 0.0153262 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0152925 |
| ENO1 | enolase 1, (alpha) | 0.0152056 |
| NBAS | neuroblastoma amplified sequence | 0.0152036 |
| ZNF148 | zinc finger protein 148 | 0.0150676 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0150584 |
| YEATS2 | YEATS domain containing 2 | 0.0149311 |
| FLNB | filamin B, beta | 0.0147737 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0145795 |
| ARF4 | ADP-ribosylation factor 4 | 0.0145387 |
| RIOK3 | RIO kinase 3 | 0.0145011 |
| SUCO | SUN domain containing ossification factor | 0.0143585 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0142585 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0142174 |
| SEPTIN7 | septin 7 | 0.0141804 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.229182 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.203377 |
| FN1 | fibronectin 1 | -0.167947 |
| EXT1 | exostosin glycosyltransferase 1 | -0.117213 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.114761 |
| GLIS3 | GLIS family zinc finger 3 | -0.0950172 |
| VCL | vinculin | -0.0841805 |
| ASPH | aspartate beta-hydroxylase | -0.0766946 |
| SQSTM1 | sequestosome 1 | -0.0754652 |
| ITGA1 | integrin, alpha 1 | -0.072207 |
| NTN4 | netrin 4 | -0.0717732 |
| NRG1 | neuregulin 1 | -0.0696711 |
| OSMR | oncostatin M receptor | -0.0687978 |
| SYT1 | synaptotagmin I | -0.065782 |
| NRP1 | neuropilin 1 | -0.0621667 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0579321 |
| TMEM156 | transmembrane protein 156 | -0.0487604 |
| HMGA2 | high mobility group AT-hook 2 | -0.0455685 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0450129 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0446345 |
| CANX | calnexin | -0.0442893 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0406039 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0398358 |
| ETV6 | ets variant 6 | -0.0387595 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0375028 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0374763 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0373806 |
| RAB31 | RAB31, member RAS oncogene family | -0.037092 |
| HLA-B | major histocompatibility complex, class I, B | -0.0360128 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0353594 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0347635 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0343294 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.033681 |
| AOPEP | aminopeptidase O (putative) | -0.0333795 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0333713 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0331171 |
| TPR | translocated promoter region, nuclear basket protein | -0.032373 |
| PALLD | palladin, cytoskeletal associated protein | -0.0321435 |
| KSR1 | kinase suppressor of ras 1 | -0.0314302 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0302996 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0302714 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0302135 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0300045 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0293256 |
| CD44 | CD44 molecule (Indian blood group) | -0.0293231 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0286554 |
| ETV1 | ets variant 1 | -0.0284629 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0280956 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0280468 |
| KLHL5 | kelch-like family member 5 | -0.0279535 |
| RAI14 | retinoic acid induced 14 | -0.0278769 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0269509 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0269323 |
| MYO10 | myosin X | -0.0268517 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0266455 |
| FHL2 | four and a half LIM domains 2 | -0.0262012 |
| RIGI | RNA sensor RIG-I | -0.0256685 |
| RNF213 | ring finger protein 213 | -0.0250778 |
| FTL | ferritin, light polypeptide | -0.0250025 |
| EFNA5 | ephrin-A5 | -0.0249229 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0247452 |
| ETNK1 | ethanolamine kinase 1 | -0.0246147 |
| PTMA | prothymosin, alpha | -0.0245791 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0245478 |
| BPTF | bromodomain PHD finger transcription factor | -0.0244127 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0242428 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0237346 |
| TMSB10 | thymosin beta 10 | -0.0235627 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0235219 |
| RAB10 | RAB10, member RAS oncogene family | -0.023336 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0232677 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0231949 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0227294 |
| SVIL | supervillin | -0.022549 |
| MKI67 | marker of proliferation Ki-67 | -0.0220873 |
| RRBP1 | ribosome binding protein 1 | -0.022081 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0220624 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0219501 |
| RASAL2 | RAS protein activator like 2 | -0.021907 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.021739 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.021711 |
| FOXP1 | forkhead box P1 | -0.0213485 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0209916 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0209784 |
| TOP1 | topoisomerase (DNA) I | -0.0208869 |
| ZNF644 | zinc finger protein 644 | -0.0207839 |
| THBS1 | thrombospondin 1 | -0.020443 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0202144 |
| GLCCI1 | glucocorticoid induced 1 | -0.0197415 |
| TNS3 | tensin 3 | -0.019641 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0196042 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0195304 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0194507 |
| LMNA | lamin A/C | -0.0192742 |
| HMGB3 | high mobility group box 3 | -0.0192009 |
| SEPTIN9 | septin 9 | -0.019176 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0191536 |
| SSH1 | slingshot protein phosphatase 1 | -0.0190604 |
| BICC1 | BicC family RNA binding protein 1 | -0.0190593 |
| ATXN1 | ataxin 1 | -0.0190231 |
