Cancer immunotherapy by PD 1 blockade Gene Set

Dataset WikiPathways Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://www.wikipathways.org/pathways/WP4585.html
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Genes

23 proteins participating in the Cancer immunotherapy by PD 1 blockade pathway from the WikiPathways Pathways 2024 dataset.

Symbol Name
BATF basic leucine zipper transcription factor, ATF-like
CD274 CD274 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD8A CD8a molecule
CD8B CD8b molecule
HLA-A major histocompatibility complex, class I, A
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IFNG interferon, gamma
JUN jun proto-oncogene
LCK LCK proto-oncogene, Src family tyrosine kinase
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa