| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Capivasertib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Capivasertib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.0740815 |
| TLE4 | transducin-like enhancer of split 4 | 0.0662652 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0614672 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0556246 |
| FNDC3B | fibronectin type III domain containing 3B | 0.055344 |
| FAM13A | family with sequence similarity 13, member A | 0.0496329 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0493462 |
| HELZ | helicase with zinc finger | 0.0458626 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0455366 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0440991 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0430753 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0430388 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0427498 |
| MEIS2 | Meis homeobox 2 | 0.0399108 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0349219 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.034897 |
| EXT1 | exostosin glycosyltransferase 1 | 0.034419 |
| VMP1 | vacuole membrane protein 1 | 0.0339444 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0332674 |
| PLAT | plasminogen activator, tissue | 0.0323409 |
| MED13 | mediator complex subunit 13 | 0.0321363 |
| GLCCI1 | glucocorticoid induced 1 | 0.030794 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0302831 |
| OGA | O-GlcNAcase | 0.0302395 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0296052 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0283181 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0278488 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.027799 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0275972 |
| LPIN1 | lipin 1 | 0.0274243 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0271654 |
| GOLGA4 | golgin A4 | 0.0270206 |
| FERMT2 | fermitin family member 2 | 0.0263963 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0258566 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0255185 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0254338 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0247139 |
| SMAD3 | SMAD family member 3 | 0.0239047 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0238335 |
| STK38L | serine/threonine kinase 38 like | 0.0237917 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0233779 |
| FNBP1 | formin binding protein 1 | 0.0230262 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.022836 |
| MEF2A | myocyte enhancer factor 2A | 0.0226016 |
| ITPKB | inositol-trisphosphate 3-kinase B | 0.0225534 |
| PDE10A | phosphodiesterase 10A | 0.0224157 |
| HMGB2 | high mobility group box 2 | 0.0221691 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.022134 |
| ZNF638 | zinc finger protein 638 | 0.0219303 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0218927 |
| INTS6 | integrator complex subunit 6 | 0.0216537 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0215701 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0214244 |
| SYNPO2 | synaptopodin 2 | 0.0214184 |
| FLNB | filamin B, beta | 0.0211191 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0209802 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0208966 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0207958 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.020732 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0207023 |
| RNF150 | ring finger protein 150 | 0.0206735 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0204846 |
| COPA | coatomer protein complex, subunit alpha | 0.0203867 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0203724 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0202252 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0201296 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0200994 |
| JMJD1C | jumonji domain containing 1C | 0.0198834 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0198209 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0197853 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0195555 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0195507 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0195486 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0194913 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0194125 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0192851 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0191721 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0184024 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0183482 |
| HOMER1 | homer scaffolding protein 1 | 0.0182114 |
| SIK3 | SIK family kinase 3 | 0.0179464 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0178955 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0177554 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0176451 |
| ZNF292 | zinc finger protein 292 | 0.0176278 |
| FOXO3 | forkhead box O3 | 0.0175521 |
| CUL3 | cullin 3 | 0.0174859 |
| TPR | translocated promoter region, nuclear basket protein | 0.0173873 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0173309 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0173176 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0171613 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0171359 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0170606 |
| ETNK1 | ethanolamine kinase 1 | 0.0168483 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0168407 |
| FHL2 | four and a half LIM domains 2 | 0.0166507 |
| FRYL | FRY-like | 0.0165958 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0164275 |
| DTNA | dystrobrevin, alpha | 0.0164266 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.016424 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.305474 |
| IGF2 | insulin-like growth factor 2 | -0.239632 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.150717 |
| LSAMP | limbic system-associated membrane protein | -0.138286 |
| VIM | vimentin | -0.116016 |
| PTMA | prothymosin, alpha | -0.0965463 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0659503 |
| SYT1 | synaptotagmin I | -0.056727 |
| TMSB10 | thymosin beta 10 | -0.0549352 |
| RPL23 | ribosomal protein L23 | -0.0537761 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0520195 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0507547 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0488086 |
| RPL34 | ribosomal protein L34 | -0.0485624 |
| FTL | ferritin, light polypeptide | -0.0482367 |
| RPS6 | ribosomal protein S6 | -0.0475166 |
| RPLP1 | ribosomal protein, large, P1 | -0.0474164 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.045496 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0454228 |
| RPL35A | ribosomal protein L35a | -0.0412959 |
| CADM2 | cell adhesion molecule 2 | -0.0397234 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0396306 |
| ZNF804A | zinc finger protein 804A | -0.0394902 |
| ACTG1 | actin gamma 1 | -0.0377194 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0375651 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0373384 |
| NDRG1 | N-myc downstream regulated 1 | -0.0371007 |
| BPTF | bromodomain PHD finger transcription factor | -0.0362016 |
| NRG1 | neuregulin 1 | -0.0360098 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0358162 |
| RPL19 | ribosomal protein L19 | -0.0347554 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0324537 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0321794 |
| RPS14 | ribosomal protein S14 | -0.0316766 |
| MAP1B | microtubule-associated protein 1B | -0.0316252 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0311513 |
| RPS19 | ribosomal protein S19 | -0.0309411 |
| CRH | corticotropin releasing hormone | -0.0309036 |
| FMN1 | formin 1 | -0.0303517 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0302224 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0294136 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.029395 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0293853 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0290439 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0279563 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0279235 |
| B2M | beta-2-microglobulin | -0.0279057 |
| RPS27 | ribosomal protein S27 | -0.0276927 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0275229 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0254793 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0254684 |
| S100A9 | S100 calcium binding protein A9 | -0.0249822 |
| RPL12 | ribosomal protein L12 | -0.0249746 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0246215 |
| RACK1 | receptor for activated C kinase 1 | -0.0245377 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0245229 |
| NREP | neuronal regeneration related protein | -0.0244221 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0243826 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.024169 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0240669 |
| RPS8 | ribosomal protein S8 | -0.0236632 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0235412 |
| RPL31 | ribosomal protein L31 | -0.0234176 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0230071 |
| COL1A1 | collagen, type I, alpha 1 | -0.0228401 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0227298 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0226715 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0224216 |
| ENO1 | enolase 1, (alpha) | -0.022301 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.021988 |
| RPS23 | ribosomal protein S23 | -0.0219876 |
| SPAG16 | sperm associated antigen 16 | -0.0219561 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0216077 |
| COL3A1 | collagen, type III, alpha 1 | -0.0214185 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0213523 |
| RPL18 | ribosomal protein L18 | -0.0211798 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.021148 |
| POTEF | POTE ankyrin domain family, member F | -0.0208646 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0208612 |
| RPS20 | ribosomal protein S20 | -0.0207614 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0207221 |
| CCND1 | cyclin D1 | -0.0207048 |
| SP100 | SP100 nuclear antigen | -0.0206008 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0204774 |
| DNM3 | dynamin 3 | -0.0202645 |
| EGR1 | early growth response 1 | -0.0199682 |
| TRIM24 | tripartite motif containing 24 | -0.019792 |
| RPL7 | ribosomal protein L7 | -0.0196351 |
| FN1 | fibronectin 1 | -0.0194684 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0193678 |
| RIGI | RNA sensor RIG-I | -0.0193648 |
| RPL38 | ribosomal protein L38 | -0.018922 |
| IER3 | immediate early response 3 | -0.0187568 |
| RPS17 | ribosomal protein S17 | -0.0187444 |
| GNAS | GNAS complex locus | -0.0187203 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.018707 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0187053 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.018643 |
| RPL39 | ribosomal protein L39 | -0.0186236 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0184143 |
